Protein Nanoparticles for Antigen Display in Vaccines | Office of Technology Transfer, NIH

Protein Nanoparticles for Antigen Display in Vaccines | Office of Technology Transfer, NIH

 Vaccine Development Opportunity:

Protein Nanoparticles for Antigen Display in Vaccines

Structural model of influenza vaccine nanoparticle with scaffold blue and conserved epitope in green. Credit: NIAID



This protein-based nanoparticle platform is based on the hepatitis B virus (HBV) capsid protein and allows presentation of immunogenic molecules such as influenza virus antigens. Influenza antigens can be inserted into an “immunogenic loop” of the HBV capsid proteins to develop nanoparticles that have the potential to be developed into a universal influenza vaccine. Read more about this exciting collaboration/licensing opportunity:https://www.ott.nih.gov/technology/e-089-2002



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