Genomics|Update|Non Communicable Diseases ► Cancer

Genomics|Update|Non Communicable Diseases

Volume 34  Number 22  June 4-11, 2015

Cancer

A risk prediction algorithm for ovarian cancer incorporating BRCA1, BRCA2, common alleles and other familial effects. 
Jervis S et al. J. Med. Genet. 2015 May 29.

Breast and ovarian cancer predisposition due to de novo BRCA1 and BRCA2 mutations. 
Golmard L et al. Oncogene 2015 Jun 1.

Cancer genetics education in a low- to middle-income country: evaluation of an interactive workshop for clinicians in Kenya. 
Hill JA et al. PLoS ONE 10(6) e0129852

Combining three antibodies nullifies feedback-mediated resistance to erlotinib in lung cancer 
Maicol Mancini, et al. Sci. Signal., 2 June 2015

Descriptive analysis of endoscopic findings in patients with a family history of colorectal cancer. 
Álvarez-Cuenllas B et al. Rev Gastroenterol Mex 2015 May 25.

Gene-panel sequencing and the prediction of breast-cancer risk. 
Easton DF et al. N. Engl. J. Med. 2015 May 27.

Genomic profiling: Building a continuum from knowledge to care 
Chen HX, et al. JAMA Oncol. 2015 May 28

HBOC multi-gene panel testing: comparison of two sequencing centers. 
Schroeder C et al. Breast Cancer Res. Treat. 2015 May 29.

Head-to-head comparison and evaluation of 92 plasma protein biomarkers for early detection of colorectal cancer in a true screening setting. 
Chen H et al. Clin. Cancer Res. 2015 May 26.

Hereditary diffuse gastric cancer syndrome: improved performances of the 2015 testing criteria for the identification of probands with a CDH1 germline mutation. 
Benusiglio PR et al. J. Med. Genet. 2015 May 29.

High prevalence of BRCA1 stop mutation c.4183C>T in the Tyrolean population: implications for genetic testing. 
Pölsler L et al. Eur. J. Hum. Genet. 2015 May 27.

Impact of an immunohistochemistry-based universal screening protocol for Lynch syndrome in endometrial cancer on genetic counseling and testing. 
Frolova AI et al. Gynecol. Oncol. 2015 Apr 137(1) 7-13

Multi-institutional external validation of urinary TWIST1 and NID2 methylation as a diagnostic test for bladder cancer. 
Fantony JJ et al. Urol. Oncol. 2015 May 28.

PD-1 blockade in tumors with mismatch-repair deficiency. 
Le Dung T et al. N. Engl. J. Med. 2015 May 30.

The clinical utility of a novel blood-based multi-transcriptome assay for the diagnosis of neuroendocrine tumors of the gastrointestinal tract. 
Modlin IM et al. Am. J. Gastroenterol. 2015 Jun 2.

The cost-effectiveness of routine testing for Lynch syndrome in newly diagnosed patients with colorectal cancer in the United States: corrected estimates. 
Grosse SD et al. Genet. Med. 2015 Jun 17(6) 510-511

The impact of genomic testing on the recommendation for radiation therapy in patients with ductal carcinoma in situ: A prospective clinical utility assessment of the 12-gene DCIS score™ result. 
Alvarado M et al. J Surg Oncol 2015 May 28.

Use of whole genome sequencing for diagnosis and discovery in the cancer genetics clinic. 
Foley SB et al. EBioMedicine 2015 Jan 2(1) 74-81

Whole-exome sequencing of metastatic cancer and biomarkers of treatment response 
Beltran H, et al. JAMA Oncol. 2015 May 28

Willingness of Japanese patients with breast cancer to have genetic testing of BRCA without burden of expenses. 
Nakagomi H et al. Breast Cancer 2015 May 30.