viernes, 27 de diciembre de 2013

Genomics|Update|Current: Heart Disease & Genomics: Familial Hypercholesterolemia


Heart Disease & Genomics: Familial Hypercholesterolemia

three hands tearing apart a heart
CDC information: Genomics and heart disease
Circulation. November 2013
  • "The guideline recognizes that adults with primary, severe elevations of LDL–C (≥190 mg/dL) have a high lifetime risk for heart related events. This is due to their lifetime exposure to markedly elevated LDL–C levels arising from genetic causes."
  • "Because the hypercholesterolemia in these high-risk individuals is often genetically determined (e.g. familial hypercholesterolemia), family screening is especially important in this group to identify additional family members who would benefit from assessment and early treatment."

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