Weekly Rundown: Moderna agrees to record settlement over COVID vaccine patents +++++

Weekly Rundown: Moderna agrees to record settlement over COVID vaccine patents FDA pilot programs, aging discoveries, and diagnostic advances led the week’s headlines. https://www.drugdiscoverynews.com/weekly-rundown-moderna-agrees-to-record-settlement-over-covid-vaccine-patents-17056 How close are scientists to stopping ALS in its tracks? Neflamapimod shows promise in slowing ALS by targeting protein clumps and restoring nerve cell function. https://www.drugdiscoverynews.com/how-close-are-scientists-to-stopping-als-in-its-tracks-17057 AI model trained on 100,000+ species learns to read and design genetic code A new biological foundation model analyzes genomic patterns across the tree of life and may accelerate disease research and synthetic biology. https://www.drugdiscoverynews.com/ai-model-trained-on-100-000-species-learns-to-read-and-design-genetic-code-17054 Engineered macrophages show promise against brain metastases Wake Forest researchers have reprogrammed macrophages to target metastatic tumors in the brain, offering a potential new approach where conventional therapies struggle. https://www.drugdiscoverynews.com/engineered-macrophages-show-promise-against-brain-metastases-17048 Gut bacteria duo may be behind chronic constipation Researchers uncover how microbes targeting the colon’s mucus may explain treatment-resistant constipation in Parkinson’s disease and other patients. https://www.drugdiscoverynews.com/gut-bacteria-duo-may-be-behind-chronic-constipation-17047