PLOS Pathogens: Exposure-Dependent Control of Malaria-Induced Inflammation in Children

PLOS Pathogens: Exposure-Dependent Control of Malaria-Induced Inflammation in Children

Leading Research to Understand, Treat, and Prevent Infectious, Immunologic, and Allergic Diseases

Visit us on the Web

Study Sheds Light on How the Immune System Protects Children from Malaria

Researchers from NIAID and the Mali International Center for Excellence in Research conducted a study in Mali that reveals children who live in regions of the world where malaria is common can mount an immune response to infection with malaria parasites that may enable them to avoid repeated bouts of high fever and illness and partially control the growth of malaria parasites in their bloodstream. The immune response may have evolved to protect young children before they acquire antibodies that reliably protect against the onset of malaria symptoms.

The study was published in PLOS Pathogens: http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1004079.