Manual for the Surveillance of Vaccine-Preventable Diseases

4th Edition, 2008-2009 & 5th Edition, 2011

As the 5th edition chapters become available, they will replace the 4th edition.

The Manual for the Surveillance of Vaccine-Preventable Diseases provides current guidelines for those directly involved in surveillance of vaccine-preventable diseases, especially personnel at the local health departments. For each of the vaccine-preventable diseases, this manual includes a chapter describing the importance of rapid case identification; the importance of surveillance; disease reduction goals; case definitions (including clinical description and case classifications); epidemiologically important data to be collected during case investigation; activities for enhancing surveillance; activities for case investigation; and activities for outbreak control. Other chapters include information on surveillance indicators; surveillance data analyses; reporting adverse events following vaccination; and enhancing surveillance. In addition, the manual includes a section reserved for insertion of state-specific guidance for VPD surveillance and extensive appendices.

List of Chapters

Chapter 1: (5th edition) Diphtheria (Updated Aug 2011)
Chapter 2 (5th edition): Haemophilus influenzae type b
(Updated Jun 2011)
Chapter 3: (5th edition) Hepatitis A (Updated Aug 2011)
Chapter 4: (5th edition) Hepatitis B (Updated Aug 2011)
Chapter 5: (5th edition) HPV (Updated Aug 2011)
Chapter 6: (5th edition) Influenza (Updated Apr 2011)
Chapter 7: Measles (Updated Apr 2009)
Chapter 8: (5th edition) Meningococcal (Updated Aug 2011)
Chapter 9: Mumps (Updated Apr 2010)
Note: See note in chapter about superseded info.
Chapter 10: (5th edition) Pertussis (Updated Jul 2011)
Chapter 11: Pneumococcal
Chapter 12: Polio Note: This chapter is not yet available.
Meanwhile, please consult last edition's Polio Chapter .

Chapter 13: (5th edition) Rotavirus (Updated Aug 2011)
Chapter 14: Rubella
Chapter 15: Congenital Rubella Syndrome
Chapter 16: (5th edition) Tetanus (Updated Oct 2011)
Chapter 17: (5th edition) Varicella (Updated Jul 2011)
Chapter 18: Surveillance Indicators
Chapter 19: Enhancing Surveillance
Chapter 20: Analysis of Surveillance Data
Chapter 21: (5th edition) Surveillance for Adverse Events Following Vaccination (Updated Oct 2011)
Chapter 22: Laboratory Support for the Surveillance of Vaccine-Preventable Diseases
Chapter 23: National Surveillance of Vaccine-Preventable Diseases
Chapter 24: (5th edition) State-Specific Surveillance of Vaccine-Preventable Diseases (Updated Oct 2011)

List of Appendices

Below is a list of appendices for the Manual of Surveillance of Vaccine-Preventable Diseases. As they are completed, a link will be provided to the appendix. Please check back often. If you wish to be notified by email when this web page is updated and hence when appendices are added, please use the Get Email Updates link located at the top of this page.

Appendix 1: Collection of Specimens for Isolation of C. diphtheriae (Ch. 1) removed temporarily for corrections
Appendix 2: Guidelines for managing a suspected case of diphtheria and for managing contacts (Ch. 1) removed temporarily for corrections
Appendix 3: CDC Diphtheria Worksheet (Ch. 1)
Appendix 4: Haemophilus influenzae Surveillance Worksheet (Ch. 2)
- Abbreviated Worksheet Option [159 KB, 1 page] (updated Nov 2010)
- Expanded Worksheet Option [83 KB, 3 pages] (updated Nov 2010)
Appendix 5: Haemophilus influenzae type b Vaccine and Extended Information Worksheet (Ch. 2) removed - Haemophilus influenzae type b Worksheet is no longer in use.
Appendix 6: Hepatitis Data Collection Worksheet [807 KB, 6 pages] (Ch. 3 and 4) (Feb 23, 2009)
Appendix 7: Measles Virus Isolation Instructions [298 KB, 4 pages] (Ch. 7) Jan 2009
Appendix 8: Measles Surveillance Worksheet (Ch. 7)
- Instructions [166 KB, 2 pages] Jan 2009
- Worksheet [385 KB, 2 pages] Jan 2009
Appendix 9: Meningococcal Disease Surveillance Worksheet (Ch. 8)
- Version 1 (formerly NETSS) [166 KB, 2 pages] Jan 2009
- Version 2 (formerly NEDSS) [385 KB, 2 pages] Jan 2009
Appendix 10: Mumps Surveillance Worksheet (Ch. 9)
- Instructions [166 KB, 2 pages] Jan 2009
- Worksheet [385 KB, 2 pages] Jan 2009
Appendix 11: Pertussis Surveillance Worksheet (Ch. 10)
- Instructions [166 KB, 2 pages] Jan 2009
- Worksheet [385 KB, 2 pages] Jan 2009
Appendix 12: Pertussis Death Worksheet (Ch. 10) removed - Pertussis Death Worksheet is no longer in use.
Appendix 13: Streptococcus pneumoniae Surveillance Worksheet [85 KB, 2 pages](Ch. 11) (Feb 2009)
Appendix 14: Suspected Polio Case worksheet Investigation of suspected case of poliomyelitis (Ch. 12)
- Worksheet [69 KB, 3 pages] May 2010
Appendix 15: Collection of Specimens for Typing of Rubella Virus (Ch. 14) Jan 2009
Appendix 16: Rubella Surveillance Worksheet (Ch. 14)
- Instructions [195 KB, 2 pages] Feb 2009
- Worksheet [616 KB, 2 pages] Feb 2009
Appendix 17: Congenital Rubella Syndrome Case Report [72 KB, 2 pages] (Ch. 15) Feb 2009
Appendix 18: Tetanus Surveillance Worksheet (Ch. 16)
- Instructions [209 KB, 2 pages] Feb 2009
- Worksheet [76 KB, 2 pages] Feb 2009
Appendix 19: Varicella Death Investigation Worksheet (Ch. 17)
- Instructions [263 KB, 2 pages] Feb 2009
- Worksheet [206 KB, 2 pages] Feb 2009
Appendix 20: Varicella Outbreak Reporting & Surveillance Worksheets (Ch. 17)
- Reporting Worksheet [176 KB, 1 page]
- Surveillance Worksheet [281 KB, 3 pages]
Appendix 21: Updated Guidelines for Evaluating Public Health Surveillance Systems [90 KB, 1 page] (Ch. 18) Jan 2009
Appendix 22: VAERS Form [70 KB, 1 page] (Ch. 21) Jan 2009
Appendix 23: CDC Specimen Submission Form [393 KB, 1 page] (Ch. 22) Jan 2009
Appendix 24: Interstate Shipment of Etiologic Agents / Packaging and Shipping of Biomedical Material [532 KB, 4 pages] (Ch. 22) Feb 2009