jueves, 4 de diciembre de 2025
The overdiagnosis debate in mental health misses the point Whether or not the criteria for mental health diagnoses are strict enough, people need help
https://www.statnews.com/2025/12/04/mental-illness-overdiagnosis-debate-treatment/
By Miranda WolpertDec. 4, 2025
Wolpert is director of mental health at Wellcome.
Paradigm Health, seeking to use AI to enroll clinical trials, partners with Roche The goal is to reach all kinds of patients, including those who don’t have access to research studies
https://www.statnews.com/2025/12/04/paradigm-health-flatiron-artificial-inteligence/
By Matthew HerperDec. 4, 2025
Senior Writer, Medicine, Editorial Director of Events
AAT Deficiency Often Missed in COPD | Could Respiratory Therapists Do More? ++++++++ +++
LATEST NEWS
AAT Deficiency Often Missed in COPD Patients
https://www.medscape.com/viewarticle/alpha-1-antitrypsin-deficiency-likely-underdiagnosed-copd-2025a1000wvv?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
Could Respiratory Therapists Do More?
https://www.medscape.com/viewarticle/expanding-scope-respiratory-therapist-2025a1000v23?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
When Alcohol and COPD Collide, Lungs Suffer More
https://www.medscape.com/viewarticle/when-alcohol-and-copd-collide-lungs-suffer-more-2025a1000wxf?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
How to Diagnose COPD and OSA in Pediatrics
https://www.medscape.com/viewarticle/diagnosing-copd-and-osa-pediatrics-challenges-and-strategies-2025a1000p5g?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
When it Comes to COPD Symptoms, Are Patients What They Eat?
https://www.medscape.com/viewarticle/when-it-comes-copd-symptoms-are-patients-what-they-eat-2025a1000mkm?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
COPD Diagnosis Reboot Identifies More At-Risk Individuals
https://www.medscape.com/viewarticle/copd-diagnosis-reboot-identifies-more-risk-individuals-2025a1000cpi?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
Mobile-Based Rehab Matches Center-Based Care in COPD
https://www.medscape.com/viewarticle/mobile-based-rehab-matches-center-based-care-copd-2025a1000r38?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
BLVR Candidates Tend Toward Heterogeneity
https://www.medscape.com/viewarticle/blvr-candidates-tend-toward-heterogeneity-2025a1000v6i?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
CLINICAL RESOURCES
Quiz: How Much Do You Know About COPD?
https://reference.medscape.com/viewarticle/865477?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
Drug Spotlight: Omalizumab
https://reference.medscape.com/drug/xolair-omlyclo-omalizumab-343444?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
Drug Interaction Checker
https://reference.medscape.com/drug-interactionchecker?ecd=mkm_ret_251204_mscpmrk_pulm_copd_etid7923171&uac=148436CN&impID=7923171
Mortality-weighted severe maternal morbidity: a novel approach to assessing maternal health outcomes
https://link.springer.com/article/10.1186/s12884-025-08526-8?utm_medium=email&utm_source=govdelivery
The U.S. Department of Health and Human Services (HHS), Office on Women’s Health (OWH) is pleased to announce the release of a new peer-reviewed publication in BMC Pregnancy and Childbirth, “Mortality-Weighted Severe Maternal Morbidity: A Novel Approach to Assessing Maternal Health Outcomes.” This open-access article adds valuable evidence to the growing body of research aimed at improving maternal health outcomes and advancing high-quality care for all pregnant women.
The publication presents a mortality-weighted SMM composite index that accounts for indicator-specific severity and additive harm from co-occurring SMM indicators. The improved SMM metric is relevant to clinicians, community partners, and policymakers in both the assessment and intervention of adverse delivery-related events. The HHS OWH encourages you to reach out and share the article with colleagues and networks working in women’s and maternal health.
Join us for the NCSACW’s Upcoming Webinar: Substance Use Trends – The Effects on Child Safety and Family Risk Factors Wednesday, December 17, 2−3 p.m. ET
Join us for the NCSACW’s Upcoming Webinar: Substance Use Trends – The Effects on Child Safety and Family Risk Factors
Wednesday, December 17, 2−3 p.m. ET
Join the National Center on Substance Abuse and Child Welfare’s (NCSACW) for a webinar exploring how substance use trends affect child safety and family risk factors. National experts will share insights from the National Opioid Environmental Scan, discuss the rise of fentanyl and other substances, and offer strategies to improve outcomes for families. Learn how evolving substance use patterns (e.g., fentanyl, stimulants, cannabis) shape child safety and family well-being.
https://cffutures.zoom.us/webinar/register/WN_jGPJ59jsSZ29KluWiX8GSg?utm_source=SAMHSA&utm_campaign=0afa3bd6b0-EMAIL_CAMPAIGN_2025_11_21_08_17_COPY_02&utm_medium=email&utm_term=0_-e218918fdf-167840245#/registration
This session highlights strategies to reduce stigma and improve parent engagement in services, assess safety and risk factors with families affected by substance use, and strengthen protective capacities in families. It’s designed for professionals across child welfare, substance use treatment, courts, and health care systems.
Topics include:
How do evolving substance use patterns affect children and families?
How does stigma shape access to services and outcomes for families affected by substance use?
What are some strategies to assess safety and risk while building protective capacities in families?
Meet our presenters:
Nancy K. Young, Ph.D., M.S.W, Executive Director of Children and Family Futures
Andrea Sivanich, Ph.D., J.D., Deputy Program Director at the Center for Children and Family Futures (CCFF)
Ultra-processed food: from first tastes to lifelong habits The Lancet Child & Adolescent Health ++... ++ (Jan 2026)
https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(25)00345-1/fulltext?dgcid=raven_jbs_etoc_email
Jan 2026
Volume 10Number 1p1-70, e1-e3
https://www.thelancet.com/journals/lanchi/issue/vol10no1/PIIS2352-4642(25)X0013-4
Global prevalence of hypertension among children and adolescents aged 19 years or younger: an updated systematic review and meta-analysis
https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(25)00281-0/abstract?dgcid=raven_jbs_etoc_feature_lanchi
Quantifying the fatal and non-fatal burden of disease associated with child growth failure, 2000–2023: a systematic analysis from the Global Burden of Disease Study 2023
https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(25)00303-7/fulltext?dgcid=raven_jbs_etoc_feature_lanchi
A day in the life: Vicky, Mum to Tiger-Lily 3 December 2025
https://rarerevolutionmagazine.com/a-day-in-the-life-vicky-mum-to-tiger-lily/
Life as a RARE parent can be a mix of worry, uncertainty and fear, but also of great joy, meaning and love. Vicky gives us an insight into parenting Tiger-Lily—the challenges, the importance of having a care circle and most importantly, of living a life of joy
My alarm goes off at 6.50am, every single morning. That’s the handover point—when the night carer finishes and my day begins with Tiger-Lily.
Life with congenital central hypoventilation syndrome (CCHS) doesn’t come with a pause button. CCHS is a rare neurological condition where the body forgets to breathe automatically, especially during sleep. For Tiger-Lily, it means relying on a ventilator at night, having a tracheostomy, and always needing careful monitoring. But it also means she’s grown up with incredible resilience, and I’ve grown right alongside her.
There are thought to be only about 200 children in the UK with CCHS, and around 5,000 worldwide—although we still think this is an underestimate where cases are non-diagnosed. It’s so rare that most doctors and nurses we meet haven’t come across it before. Parenting a child with CCHS makes you a nurse, an advocate, a cheerleader and a project manager all rolled into one.
Mornings: waking with alarms
Even when brushing my teeth, I’m listening out for the ventilator alarm. It often goes off when Tiger-Lily stirs, and even if it’s nothing serious, my heart still skips. But she’s amazing at managing things herself now—she’ll wake up, take off her oxygen probe and ventilator, and pop on her Swedish nose (a little filter for her trach).
After that, mornings look much like anyone else’s: loo, teeth, clothes, breakfast. The difference is the extra checklist—spare Swedish noses, suction machine, saline, catheters, charger. It’s second nature now, but still a juggling act.
The school run: book bags and beyond
Getting out of the house is always an operation—school bag plus wheely box, suction machine and all the backups. At school she’s greeted by her one-to-one carer and I head to work with my phone on loud, just in case.
Sometimes the phone does ring and my stomach drops. Once she fainted at school due to dehydration. For another child it would’ve been a sick day; for Tiger-Lily, it was an emergency. But those moments are rare. Most days she’s just like her classmates—running into school, seeing friends and learning new things.
Afternoons and evenings
After school, Tiger-Lily might go to a club—she loves dancing and recently shone in a Wizard of Oz show. Seeing her beam on stage made me so proud. On quieter days we’ll head to the park or snuggle up for reading.
Evenings have their rhythm: dinner, bath (extra careful around her trach), then bed. She’s usually asleep by 8pm, with her oxygen monitor on. At 9pm her carer arrives for the night shift, and I can exhale, knowing she’s safe and watched over until morning.
The circle of care
We’re surrounded by people I trust—from carers to school staff. That consistency means I can let Tiger-Lily step out into the world with confidence. Trust is everything, and I’ve learnt that having the right people around us makes the biggest difference.
How it’s changed me
Tiger-Lily has transformed me. I used to be laid-back; now I’m determined and focused. I’ve even become a runner—something I’d never imagined and I’ve now run two 10ks. Running helps me process everything, and it shows both of us that we can keep moving forward, no matter what.
Keep me breathing
One huge source of hope has been Keep Me Breathing, the children’s charity based in Hove. They’re pioneering new technology for kids with CCHS, including the VENTO—a wearable CO₂ monitor that’s 90% lighter and 20 times smaller than the bulky equipment we currently use—and, in the longer term, an advanced breathing pacemaker.
The thought of something portable that could alert me if her breathing dips and then automatically help her to breathe will be life-changing. It would mean less constant fear, more freedom, and even the possibility of things like swimming or travelling abroad once her tracheostomy can be reversed.
Just as importantly, Keep Me Breathing brings families together. When you’re living with something so rare, connecting with people who get it is invaluable. That sense of community has carried me through.
Our normal
Tiger-Lily is seven now and thriving. She’s independent, clever and at that age where hugs at the school gate are so uncool. I secretly love that, because it means she’s just like any other child her age.
Yes, the medical side is always there—alarms, equipment checks, planning. But our life is full of joy too: school runs, homework, bedtime stories, dance shows, days in the park.
This is our normal. Busy, sometimes scary, but overflowing with pride and love. And Tiger-Lily amazes me every single day.
ASH 2025 Preview: Myeloma Abstracts to Watch For +++
News & Perspectives:
ASH 2025 Preview: Myeloma Abstracts to Watch For
ASH 2025 Preview: Myeloma Abstracts to Watch For
Manni Mohyuddin, MD
https://www.medscape.com/viewarticle/ash-2025-preview-myeloma-abstracts-watch-2025a1000wt2?ecd=wnl_edit_tpal_etid7924649&uac=148436CN&impID=7924649
Man in Seventies With Blink-Induced Visual Tilt From Stroke
Man in Seventies With Blink-Induced Visual Tilt From Stroke
Wolfgang Paik
https://www.medscape.com/viewarticle/man-seventies-blink-induced-visual-tilt-stroke-2025a1000xrc?ecd=wnl_edit_tpal_etid7924649&uac=148436CN&impID=7924649
Medscape UK
December 03, 2025
Trump GLP-1 Deal ‘Move in Right Direction’
Trump GLP-1 Deal ‘Move in Right Direction’
Caroline Messer, MD
https://www.medscape.com/viewarticle/trump-glp-1-deal-move-right-direction-2025a1000wt0?ecd=wnl_edit_tpal_etid7924649&uac=148436CN&impID=7924649
December 02, 2025
miércoles, 3 de diciembre de 2025
Microbial warning signs that predict death risk in severe pneumonia
https://www.news-medical.net/news/20251203/Microbial-warning-signs-that-predict-death-risk-in-severe-pneumonia.aspx
Researchers uncover a microbial signature in the lungs of severe pneumonia patients. Could this help explain survival differences and hint at new paths for earlier, more accurate prognosis?
Air pollution weakens the life-extending benefits of exercise
https://www.news-medical.net/news/20251203/Air-pollution-weakens-the-life-extending-benefits-of-exercise.aspx
A large multi-country study identifies the air pollution levels at which the health benefits of regular physical activity start to decline, offering clearer guidance for staying active in areas with rising PM2.5 exposure.
Editorial p1265 Lenacapavir—time to change the game for everyone The Lancet Infectious Diseases +++ +...
Human papillomavirus (HPV) type 16 and type 18 antibody concentrations after a single dose of bivalent HPV vaccine in girls aged 9–14 years compared with three doses of quadrivalent HPV vaccine in women aged 18–25 years in Costa Rica (PRIMAVERA): a non-randomised, open-label, immunobridging, non-inferiority trial
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00284-1/fulltext?dgcid=hubspot_update_feature_updatealerts_laninf&utm_campaign=update-laninf&utm_medium=email&_hsenc=p2ANqtz--L_JGaXKO7ug0oIeUX3ULppCoCTcUTGP1Tr_FT-L2j7c1BtesnbmSWzZF9awNInGpB2H9dcMtife1hXQb20AJGrltheg&_hsmi=392624890&utm_content=392596276&utm_source=hs_email
Estimating measles susceptibility and transmission patterns in Italy: an epidemiological assessment
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00293-2/abstract?utm_campaign=update-laninf&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_laninf&_hsenc=p2ANqtz--n4sI29JZqk_zX2t2pU_23ggeyb_PDKrClL0-NlbBaNORHjsJF9hYInckV6I0r6-_N6lYjp4eyfTofAAbpjlR5g0Av8w&_hsmi=392624890&utm_content=392596276&utm_source=hs_email
The participation of people deprived of liberty in tuberculosis vaccine trials: should they be protected from research, or through research?
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00305-6/abstract?utm_campaign=update-laninf&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_laninf&_hsenc=p2ANqtz-__pg6tk7RuxK_aQ-hdrK6QDwq-QGlqXlDT2Bst8Mby_wGy5lLrvj74SsCX9Cj_OxMoh80-dJB9JsWutLwgIrk7K9wdcQ&_hsmi=392624890&utm_content=392596276&utm_source=hs_email
Editorial
p1265
Lenacapavir—time to change the game for everyone
The Lancet Infectious Diseases
https://www.thelancet.com/journals/laninf/issue/vol25no12/PIIS1473-3099(25)X0012-8
martes, 2 de diciembre de 2025
lunes, 1 de diciembre de 2025
Are Sexual Side Effects Emerging With GLP-1 Agonists? Mónica M. Bernardo +++++ ++ +
Just In
Are Sexual Side Effects Emerging With GLP-1s?
https://www.medscape.com/viewarticle/are-sexual-side-effects-emerging-glp-1-agonists-2025a1000x7g?ecd=wnl_tp10_daily_251128_MSCPEDIT_etid7910876&uac=148436CN&impID=7910876
This May Help Reduce Lead-Related Alzheimer’s Risk
https://www.medscape.com/viewarticle/physical-activity-may-reduce-lead-related-alzheimers-risk-2025a1000x2l?ecd=wnl_tp10_daily_251128_MSCPEDIT_etid7910876&uac=148436CN&impID=7910876
Finerenone Offers Hope for Kidney Disease in T1D
https://www.medscape.com/viewarticle/finerenone-offers-hope-kidney-disease-type-1-diabetes-2025a1000uzi?ecd=wnl_tp10_daily_251128_MSCPEDIT_etid7910876&uac=148436CN&impID=7910876
Youth Turning to Generative AI for Mental Health Advice
https://www.medscape.com/viewarticle/us-youth-turning-generative-ai-mental-health-advice-2025a1000x2g?ecd=wnl_tp10_daily_251128_MSCPEDIT_etid7910876&uac=148436CN&impID=7910876
Germany: A Magnet for Foreign Doctors, but Losing Its Own
https://www.medscape.com/viewarticle/germany-magnet-foreign-doctors-losing-its-own-2025a1000x8b?ecd=wnl_tp10_daily_251128_MSCPEDIT_etid7910876&uac=148436CN&impID=7910876
Most Popular
When to Test for Fungal Infections?
https://www.medscape.com/viewarticle/mycoses-and-misdiagnoses-when-test-fungal-infections-2025a1000w5g?ecd=wnl_tp10_daily_251128_MSCPEDIT_etid7910876&uac=148436CN&impID=7910876
Why Hypersomnias Still Take Years to Diagnose
https://www.medscape.com/viewarticle/8-year-yawn-why-hypersomnia-takes-so-long-diagnose-2025a1000x6l?ecd=wnl_tp10_daily_251128_MSCPEDIT_etid7910876&uac=148436CN&impID=7910876
Fast Five Quiz
Idiopathic Pulmonary Fibrosis Comorbidities & Complications
https://reference.medscape.com/viewarticle/fast-five-quiz-idiopathic-pulmonary-fibrosis-comorbidities-2025a1000dup?ecd=wnl_tp10_daily_251128_MSCPEDIT_etid7910876&uac=148436CN&impID=7910876
Why potatoes and grains can’t replace each other in a healthy diet
https://www.news-medical.net/news/20251201/Why-potatoes-and-grains-cane28099t-replace-each-other-in-a-healthy-diet.aspx
Researchers have shown that white potatoes provide crucial nutrients that Americans lack, yet swapping them for grains triggers significant losses in iron, folate, and other essential nutrients, reshaping our understanding of “healthy carbs.”
Hidden Epidemic: MASLD in Obesity | CRC Risk From Running? ++++++ +++
EXPERT INSIGHTS
Hidden Epidemic: MASLD in Obesity
https://www.medscape.com/viewarticle/obesity-and-masld-epidemic-hiding-plain-sight-2025a1000vsw?ecd=mkm_ret_251130_mscpmrk_gastro_perspectives_etid7912888&uac=148436CN&impID=7912888
Does Long-Distance Running Up CRC Risk?
https://www.medscape.com/viewarticle/does-marathon-running-increase-colorectal-cancer-risk-2025a1000uy6?ecd=mkm_ret_251130_mscpmrk_gastro_perspectives_etid7912888&uac=148436CN&impID=7912888
Nutrition & Health: What We Do and Don't Know
https://www.medscape.com/viewarticle/what-we-know-and-dont-know-about-nutrition-and-health-2025a1000qfa?ecd=mkm_ret_251130_mscpmrk_gastro_perspectives_etid7912888&uac=148436CN&impID=7912888
A Preventive Care Roadmap for IBD
https://www.medscape.com/viewarticle/preventive-care-roadmap-ibd-2025a1000nkr?ecd=mkm_ret_251130_mscpmrk_gastro_perspectives_etid7912888&uac=148436CN&impID=7912888
Diverticular Disease Demystified
https://www.medscape.com/viewarticle/diverticular-disease-demystified-myths-risks-and-modern-care-2025a1000imo?ecd=mkm_ret_251130_mscpmrk_gastro_perspectives_etid7912888&uac=148436CN&impID=7912888
Why Is EPI Often Missed?
https://www.medscape.com/viewarticle/exocrine-pancreatic-insufficiency-risk-awareness-2025a1000lcz?ecd=mkm_ret_251130_mscpmrk_gastro_perspectives_etid7912888&uac=148436CN&impID=7912888
POPULAR COMMENTARIES
‘We’ve Been Misled About Alcohol and Health’
https://www.medscape.com/viewarticle/alcohol-bad-heart-brain-and-cognition-2025a1000qnb?ecd=mkm_ret_251130_mscpmrk_gastro_perspectives_etid7912888&uac=148436CN&impID=7912888
Pancreatic Cancer: Who Should Get Screened?
https://www.medscape.com/viewarticle/pancreatic-cancer-who-should-get-screened-2025a1000r64?ecd=mkm_ret_251130_mscpmrk_gastro_perspectives_etid7912888&uac=148436CN&impID=7912888
The High Road to Avoid Alcohol
https://www.medscape.com/viewarticle/high-road-avoid-alcohol-2025a1000w07?ecd=mkm_ret_251130_mscpmrk_gastro_perspectives_etid7912888&uac=148436CN&impID=7912888
Rare Clinical Spotlight Exploring Castleman Disease, Cold Agglutinin Disease, and Acute Intermittent Porphyria CME/CNE/CPE Hyatt Regency Orlando Friday, December 5, 2025 | 11:30 AM - 1:00 PM ET
https://na.eventscloud.com/website/87038/
Join us for a truly unique 90-minute deep dive into three rare but clinically significant conditions, Castleman disease (CD), cold agglutinin disease (CAD), and acute intermittent porphyria (AIP), led by six expert faculty who specialize in diagnosing and treating these complex disorders.
Important Long-COVID Lessons From AIDS Researchers Sara Novak November 20, 2025 +++++
Important Long-COVID Lessons From AIDS Researchers
Sara Novak
https://www.medscape.com/viewarticle/important-long-covid-lessons-aids-researchers-2025a1000wdc?ecd=mkm_ret_251201_mscpmrk-OUS_InFocus_etid7910620&uac=148436CN&impID=7910620
November 20, 2025
Achieving Lasting Remission for HIV
https://www.medscape.com/s/viewarticle/achieving-lasting-remission-hiv-2025a1000wq1?ecd=mkm_ret_251201_mscpmrk-OUS_InFocus_etid7910620&uac=148436CN&impID=7910620
The Patient Portal That Patients Can’t Navigate
https://www.medscape.com/viewarticle/patient-portal-patients-cant-navigate-2025a1000wbx?ecd=mkm_ret_251201_mscpmrk-OUS_InFocus_etid7910620&uac=148436CN&impID=7910620
Which Regimen Works Best for Late-Diagnosis HIV Care?
https://www.medscape.com/viewarticle/which-regimen-works-best-late-diagnosis-hiv-care-2025a1000sja?ecd=mkm_ret_251201_mscpmrk-OUS_InFocus_etid7910620&uac=148436CN&impID=7910620
‘We Are Getting Closer to Finding a Real Cure for HIV’
https://www.medscape.com/viewarticle/we-are-getting-closer-finding-real-cure-hiv-2025a1000v3j?ecd=mkm_ret_251201_mscpmrk-OUS_InFocus_etid7910620&uac=148436CN&impID=7910620
UK Cuts Aid to Global Disease Initiative by 15% to £850m
https://www.medscape.com/s/viewarticle/uk-cuts-aid-global-disease-initiative-15-850-million-pounds-2025a1000ve6?ecd=mkm_ret_251201_mscpmrk-OUS_InFocus_etid7910620&uac=148436CN&impID=7910620
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