jueves, 31 de julio de 2025

Infant brain activity shows faster maturation after general anesthesia

https://www.news-medical.net/news/20250730/Infant-brain-activity-shows-faster-maturation-after-general-anesthesia.aspx

Several healthy eating patterns may reduce the risk of type 2 diabetes across diverse ethnic groups

https://www.news-medical.net/news/20250730/Several-healthy-eating-patterns-may-reduce-the-risk-of-type-2-diabetes-across-diverse-ethnic-groups.aspx

CPADS enables comprehensive analysis of drug resistance across 44 cancer types

https://www.news-medical.net/news/20250730/CPADS-enables-comprehensive-analysis-of-drug-resistance-across-44-cancer-types.aspx

Immunocompromised people are susceptible to skin cancer caused directly by beta-HPV

https://www.news-medical.net/news/20250730/Immunocompromised-people-susceptible-to-skin-cancer-caused-directly-by-beta-HPV.aspx

Perceived sickness activates real immune responses

https://www.news-medical.net/news/20250731/Perceived-sickness-activates-real-immune-responses.aspx In a new experiment, scientists used virtual reality to show that the brain can sense virtual infection to trigger the body’s immune system, before the first microbe ever makes contact.

Cancer cells use energy surge to survive physical squeezing

https://www.news-medical.net/news/20250731/Cancer-cells-use-energy-surge-to-survive-physical-squeezing.aspx

Promising treatment slows liver cancer by inhibiting fat enzyme

https://www.news-medical.net/news/20250731/Promising-treatment-slows-liver-cancer-by-inhibiting-fat-enzyme.aspx

Scarred liver tissue creates fertile ground for cancer development

https://www.news-medical.net/news/20250731/Scarred-liver-tissue-creates-fertile-ground-for-cancer-development.aspx

AI uncovers new lipid-lowering effects in existing FDA-approved drugs

https://www.news-medical.net/news/20250731/AI-uncovers-new-lipid-lowering-effects-in-existing-FDA-approved-drugs.aspx

Cancer-associated fibroblasts exhibit paradoxical effects on immunotherapy

https://www.news-medical.net/news/20250731/Cancer-associated-fibroblasts-exhibit-paradoxical-effects-on-immunotherapy.aspx

Novel insights from lymphoid structures: Lessons from colorectal cancer research

https://www.news-medical.net/news/20250731/Novel-insights-from-lymphoid-structures-Lessons-from-colorectal-cancer-research.aspx

An overview of FeNO guidelines in clinical practice

https://www.news-medical.net/whitepaper/20250728/An-overview-of-FeNO-guidelines-in-clinical-practice.aspx Fractional exhaled Nitric Oxide (FeNO) is widely used in both primary and secondary care settings across the world. Many regions recommend incorporating FeNO-guided management into their clinical standards, and resulting FeNO-related guidelines can vary across the UK and other countries. The following explores and compares these approaches.

L-Theanine Benefits: Does This Green Tea Amino Acid Really Reduce Stress and Anxiety?

https://www.news-medical.net/health/L-Theanine-Benefits-Does-This-Green-Tea-Amino-Acid-Really-Reduce-Stress-and-Anxiety.aspx

Do Collagen Supplements Work? Science-Backed Benefits for Skin, Joints, and Muscles

https://www.news-medical.net/health/Do-Collagen-Supplements-Work-Science-Backed-Benefits-for-Skin-Joints-and-Muscles.aspx

Why Is Plague Still a Threat? Historical Lessons and Future Preparedness

https://www.news-medical.net/health/Why-Is-Plague-Still-a-Threat-Historical-Lessons-and-Future-Preparedness.aspx

Beta-HPV can directly cause skin cancer in immunocompromised people NIH case study finds virus drives creation of cancer cells in context of defective T cells.

https://www.nih.gov/news-events/news-releases/beta-hpv-can-directly-cause-skin-cancer-immunocompromised-people

Pemphigoid or Psoriasis? 65-Year-Old’s Remote Diagnosis Race Pauline Koniarczyk Medscape UK July 30, 2025

https://www.medscape.com/viewarticle/pemphigoid-or-psoriasis-65-year-olds-remote-diagnosis-race-2025a1000k55

Myeloma Expert: Is Early Immunotherapy a Game Changer? Mary Ellen Schneider July 31, 2025 ++++

https://www.medscape.com/viewarticle/myeloma-expert-early-immunotherapy-game-changer-2025a1000kcz Me-Too Cancer Drugs Not Often Compared to Original Edited by Gargi Mukherjee https://www.medscape.com/viewarticle/me-too-cancer-drugs-not-often-compared-original-2025a1000kat July 31, 2025 Dupilumab Helps Sustain Cancer Treatment by Controlling ADC Skin Toxicities Edited by Deepa Varma https://www.medscape.com/viewarticle/dupilumab-helps-sustain-cancer-treatment-controlling-adc-2025a1000kal July 30, 2025 Novel Combo Boosts Survival in IDH1-Mutated AML Edited by Susan Ruel, PhD https://www.medscape.com/viewarticle/novel-combo-boosts-survival-idh1-mutated-aml-2025a1000kam July 30, 2025

One Team, One Goal: The Key to Better Patient Outcomes in Early Breast Cancer Management Authors: Fatima Cardoso, MD, FESMO, ESCO; Nadia Harbeck, MD, PhD; Shani Paluch, MBBS, MSc

https://www.medscape.org/viewarticle/1002593_sidebar11?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_250731-ES_LANG-HONC-1002593-cta

Absolute and relative risks of mental disorders in families: a Danish register-based study + +... +

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00196-8/abstract?utm_campaign=update-lanpsy&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanpsy&_hsenc=p2ANqtz-8tognIlQrPC6Be1TcBmBvkeP2pAETLaoOynZcUTQa_dvYnE4eGP_jwF_nugSWGTggIS99xBcryEVVKf1-s-RIXCQ96KQ&_hsmi=373683497&utm_content=372960347&utm_source=hs_email Editorial p543 Mental health in all policies The Lancet Psychiatry https://www.thelancet.com/journals/lanpsy/issue/vol12no8/PIIS2215-0366(25)X0008-0 Real-world effectiveness of clozapine augmentation with antidepressants: within-subject data evidence from two European nationwide cohorts https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00163-4/abstract?utm_campaign=update-lanpsy&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanpsy&_hsenc=p2ANqtz--jKETkNPz5vRR-eXGu3XqUNo3GiAbqHs3i0cBEGhM5Qoa-p6jdUOY0-diZCrerm6Ios4nGdyZbYBwGE3TCGWImXW_Lyg&_hsmi=373683497&utm_content=372960347&utm_source=hs_email

Editorial Daring to dream of long-acting HIV prevention + + +...

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00194-8/fulltext?dgcid=raven_jbs_etoc_email Aug 2025 Volume 12Number 8e537-e602 https://www.thelancet.com/journals/lanhiv/issue/vol12no8/PIIS2352-3018(25)X0008-4 Safety and immunogenicity of investigational tuberculosis vaccine M72/AS01E–4 in people living with HIV in South Africa: an observer-blinded, randomised, controlled, phase 2 trial https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00124-9/fulltext?dgcid=raven_jbs_etoc_feature_lanhiv

miércoles, 30 de julio de 2025

A 15-year study reveals which diets best protect your brain and heart in later life

https://www.news-medical.net/news/20250729/A-15-year-study-reveals-which-diets-best-protect-your-brain-and-heart-in-later-life.aspx

Volunteer for Clinical Studies

https://www.niaid.nih.gov/?utm_campaign=+65772947&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

Eating Right for Chronic Kidney Disease

https://www.nih.gov/?utm_campaign=+65772947&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial +...

https://www.thelancet.com/journals/landia/article/PIIS2213-8587(25)00092-0/abstract?utm_campaign=update-landia&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_landia&_hsenc=p2ANqtz--ZCWxoSYbfW_hoPZEZ8PxFih0e9l3oIMTlYwp1DqA7I_-g-MKK7nN6VJVN6BCtaWDjIe3Znn437RGmMH2G7ncFLgBPKg&_hsmi=373496280&utm_content=372959207&utm_source=hs_email Aug 2025 Volume 13Number 8p635-722, e11 https://www.thelancet.com/journals/landia/issue/vol13no8/PIIS2213-8587(25)X0008-5

Editorial Embracing the challenges in asthma care through innovation

https://www.thelancet.com/journals/lanres/issue/vol13no8/PIIS2213-2600(25)X0008-4

Global Epidemiology of Chronic Respiratory Disease

https://www.thelancet.com/series-do/global-epidemiology-chronic-respiratory-disease?dgcid=raven_jbs_etoc_feature_lanrescrd25

How Nature’s Symmetry Might Help Us See Early Warning Signs of Cancer July 30, 2025 By: Ming Zheng

https://www.nist.gov/blogs/taking-measure/how-natures-symmetry-might-help-us-see-early-warning-signs-cancer

Long-term survival and cure fraction estimates for paediatric central nervous system tumours in 31 European countries (EUROCARE-6): a population-based study +...

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00297-9/abstract?dgcid=raven_jbs_etoc_feature_lanonc Editorial p981 Cancer drug discovery at warp speed: can AI deliver? The Lancet Oncology https://www.thelancet.com/journals/lanonc/issue/vol26no8/PIIS1470-2045(25)X0008-5

The OurFutures Vaping eHealth intervention to prevent e-cigarette use among adolescent students in Australia: a cluster randomised controlled trial +...

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00145-8/fulltext?dcig=raven_jbs_etoc_feature_lanpub Aug 2025 Volume 10Number 8e640-e721 https://www.thelancet.com/journals/lanpub/issue/vol10no8/PIIS2468-2667(25)X0008-6

Optimizing Outcomes for Thyroid Cancer With NTRK Gene Fusions: Precision Care, Patient Impact Authors: Jaume Capdevila, MD, PhD; Gary Bloom; Umberto Malapelle, PhD; Lori J. Wirth, MD

https://www.medscape.org/viewarticle/1002660?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250729-OUS-HONC-1002660-cta

Advancing Treatment for HER2-Positive Advanced Breast Cancer: Expert Analysis of the Latest Developments Authors: Judy King, MRCP, PhD; Peter Fasching, MD

https://www.medscape.org/viewarticle/1002765

Advanced HER2-Positive Gastric/GEJ Cancers: Expert Insights on Current and Future Strategies Authors: Frédérique Penault-Llorca, MD, PhD; Elizabeth Smyth, MD; Eric Van Cutsem, MD, PhD

https://www.medscape.org/viewarticle/1002494?src=wgt_dfp_popup_org_1002494&src=layer_105_medscape.com

New Antibody-Drug Conjugates Expand Treatment Options for HER2+ and MET+ Lung Cancer Mark G. Kris, MD July 29, 2025

https://www.medscape.com/viewarticle/new-antibody-drug-conjugates-expand-treatment-options-her2-2025a1000igm

Targeted but Toxic? Addressing the Safety Challenges of Antibody-Drug Conjugates in Metastatic Breast Cancer Suchandrima Bhowmik, MSc July 30, 2025

https://www.medscape.com/viewarticle/targeted-toxic-addressing-safety-challenges-antibody-drug-2025a1000imj

Stereotactic Radiation Cuts Neurologic Deaths in SCLC and Brain Metastases Edited by Gargi Mukherjee July 30, 2025

https://www.medscape.com/viewarticle/stereotactic-radiation-cuts-neurologic-deaths-sclc-and-brain-2025a1000k6i

Deaths From Prostate Cancer vs Other Causes: Long-Term Data on NCCN-Based Care Megan Brooks July 30, 2025

https://www.medscape.com/viewarticle/deaths-prostate-cancer-vs-other-causes-long-term-data-nccn-2025a1000k68

Cannabis and Lung Cancer: A Link Stronger Than It Appears Stephanie Lavaud July 30, 2025

https://www.medscape.com/viewarticle/cannabis-and-lung-cancer-link-stronger-than-it-appears-2025a1000k6v

Patients With IBD and PSC Face Elevated CRC Risk Edited by Mandeep Singh Rawat Medscape UK July 30, 2025

https://www.medscape.com/viewarticle/patients-ibd-and-psc-face-elevated-crc-risk-2025a1000jvf

EMA Backs First Oral, On-Demand Treatment for Hereditary Angioedema Zeel Mehta Published July 28, 2025 Updated July 29, 2025

https://www.medscape.com/viewarticle/ema-backs-first-oral-treatment-hereditary-angioedema-2025a1000jvq?ecd=wnl_edit_tpal_etid7604992&uac=148436CN&impID=7604992

Novel Long-Term Findings for Post-HRT Fracture Risk in Menopausal Women Marcia Frellick July 29, 2025

https://www.medscape.com/viewarticle/novel-long-term-findings-post-hrt-fracture-risk-menopausal-2025a1000jyi?ecd=wnl_edit_tpal_etid7604992&uac=148436CN&impID=7604992

martes, 29 de julio de 2025

Understanding Different Types of Dementia

https://www.nia.nih.gov/sites/default/files/understanding-types-dementia_0.pdf?&utm_source=nia-eblast&utm_medium=email&utm_campaign=general-20250729

From Johnson to Reagan: Experts Unpack the Rhetoric That Framed Medicare’s Birth Edited by Lisa Gillespie July 29, 2025

https://www.medscape.com/viewarticle/johnson-reagan-experts-unpack-rhetoric-framed-medicares-2025a1000jwo

More Data Cement COVID’s Impact on Patients With Cancer Edited by Gargi Mukherjee July 28, 2025

https://www.medscape.com/viewarticle/more-data-cement-covids-impact-patients-cancer-2025a1000jst

EMA Greenlights Voranigo for IDH-Mutant Grade 2 Glioma Joyani Das July 28, 2025

https://www.medscape.com/viewarticle/ema-greenlights-voranigo-idh-mutant-grade-2-glioma-2025a1000jvb

Doctors’ Own End-of-Life Choices Defy Common Medical Practice Cristina Ferrario July 29, 2025

https://www.medscape.com/viewarticle/doctors-own-end-life-choices-defy-common-medical-practice-2025a1000k01

Cilta-cel CAR T: Myeloma ‘Cure’ and Conjecture Manni Mohyuddin, MD July 28, 2025

https://www.medscape.com/viewarticle/cilta-cel-car-t-myeloma-cure-and-conjecture-2025a1000jnp

Older Patients With Breast Cancer Face Inconsistent Bone Health Management Across Centres Edited by Vineeta Teotia Medscape UK July 28, 2025

https://www.medscape.com/viewarticle/older-patients-breast-cancer-face-inconsistent-bone-health-2025a1000jl7

EMA Recommends Romvimza for Tenosynovial Giant Cell Tumor Zeel Mehta July 28, 2025

https://www.medscape.com/viewarticle/ema-recommends-romvimza-tenosynovial-giant-cell-tumor-2025a1000jw3

Alcohol and Pancreatic Cancer: New Evidence About Risk Amy Norton July 29, 2025

https://www.medscape.com/viewarticle/alcohol-and-pancreatic-cancer-new-evidence-about-risk-2025a1000jzi

Educating, Empowering, and Engaging: A Focus on HER2-Activating Mutations in NSCLC Authors: Eric K. Singhi, MD; Thomas Newsom-Davis, FRCP, PhD; Soo-Ryum (Stewart) Yang, MD

https://www.medscape.org/viewarticle/1002375?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250729-OUS-HONC-1002375-cta

Clinical Advances in the Management of Lung Cancer

https://www.medscape.org/sites/advances/management-lung-cancer?sso=true&uac=148436CN&src=mkmcmr_driv_clinad_mscpedu

lunes, 28 de julio de 2025

Which GLP-1 meds have the most side effects? Study of 60,000 Facebook posts gives answers

https://www.news-medical.net/news/20250728/Which-GLP-1-meds-have-the-most-side-effects-Study-of-60000-Facebook-posts-gives-answers.aspx

NIH researchers develop AI agent that improves accuracy of gene set analysis by leveraging expert-curated databases

https://www.nih.gov/news-events/news-releases/nih-researchers-develop-ai-agent-improves-accuracy-gene-set-analysis-leveraging-expert-curated-databases

Advancing Patient-Centered Care in mCRPC: Exploring PARP Inhibitor Combinations Authors: Neeraj Agarwal, MD, FASCO; Karim Fizazi, MD, PhD

https://www.medscape.org/viewarticle/1002353?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250728-OUS-HONC-1002353-cta

FDA Expert Panel on Menopause and Hormone Replacement Therapy for Women

World Hepatitis Day: Reducing the Risk of Hepatitis C

https://www.hiv.gov/blog/world-hepatitis-day-reducing-the-risk-of-hepatitis-c?j=2736826&sfmc_sub=6992026&l=6498_HTML&u=67449027&mid=100006181&jb=0

Armoring up CAR T cells to fight solid tumors ArsenalBio equips T cells with multiple weapons to identify, attack, and persist against tumors, bringing the power of CAR T cell technology to solid cancers.

https://www.drugdiscoverynews.com/armoring-up-car-t-cells-to-fight-solid-tumors-16276?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-8IKWpHd7Maql4R02R3PQ_XIRMr6NDj9wrbe1Kc12A7aTzMeo6zEahBEpoRRNaVEHQFtLs0oukn4ke9VlsHis05zRNXiw&_hsmi=372996550&utm_content=372996550&utm_source=hs_email

Tracking inflammation across tissues with a targeted PET probe Researchers developed a PET probe that targets all immune cells to help diagnose and monitor inflammatory diseases.

https://www.drugdiscoverynews.com/tracking-inflammation-across-tissues-with-a-targeted-pet-probe-16287?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--EZy35HmvaA4IPGM_BvOhgm-2wmVJvodjgOFZXru34a-b5BtMDYO0tQVyfSSKXuxbvzc1uhbMg_oF0_vOIx5iszQQKsg&_hsmi=372996550&utm_content=372996550&utm_source=hs_email

Machine learning drives progress in fibrosis treatment Insilico’s Phase 2a trial of an AI-designed therapy marks a milestone in data-driven drug development.

https://www.drugdiscoverynews.com/machine-learning-drives-progress-in-fibrosis-treatment-16515?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9tNMD9PiAxVORbc4q3E1Zp7wjCX65yBTkYbyosVe-Jqg0qIfZvfDRLSfJaUZNZAUWUwkUZXXPT43TN_PTZ_qQTEIs1-Q&_hsmi=372996550&utm_content=372996550&utm_source=hs_email

Clinical Case: Kidney Cancer Hides in 6-mm Breast Lesion Wolfgang Paik Medscape UK July 28, 2025

https://www.medscape.com/viewarticle/clinical-case-kidney-cancer-hides-6-mm-breast-lesion-2025a1000jt5

Don’t Forget These Infectious Disease Screenings +++++ ++ +++++

News Don't Forget These Infectious Disease Screenings https://www.medscape.com/viewarticle/dont-forget-these-infectious-risk-based-disease-screenings-2025a1000f2o?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Europe's Hepatitis A Outbreak: What You Need to Know https://www.medscape.com/viewarticle/europes-hepatitis-outbreak-what-you-need-know-2025a1000h53?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Most Kids Never Get the Cure for Hepatitis C https://www.medscape.com/viewarticle/clinicians-can-prescribe-cure-hepatitis-c-most-kids-never-2025a1000a42?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Does Metabolic Dysfunction Affect Liver Fibrosis in Hep B? https://www.medscape.com/viewarticle/does-metabolic-dysfunction-associated-steatotic-liver-2025a1000hwa?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Preventing Hepatitis B Reactivation: Updated Guidance https://www.medscape.com/viewarticle/preventing-hepatitis-b-reactivation-updated-clinical-2025a10005oi?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Vaccines Hepatitis A Vaccine Inactivated https://reference.medscape.com/drug/vaqta-havrix-hepatitis-a-vaccine-inactivated-343150?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Hepatitis A/B Vaccine https://reference.medscape.com/drug/twinrix-hepatitis-a-b-vaccine-343152?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Overview & Treatment Hepatitis A https://emedicine.medscape.com/article/177484-overview?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Hepatitis B https://emedicine.medscape.com/article/177632-overview?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Hepatitis C https://emedicine.medscape.com/article/177792-overview?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Hepatitis D https://emedicine.medscape.com/article/178038-overview?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337 Hepatitis E https://emedicine.medscape.com/article/178140-overview?ecd=mkm_ret_250728_mscpmrk-OUS_InFocus_etid7594337&uac=148436CN&impID=7594337

domingo, 27 de julio de 2025

Patient involvement in clinical trials: a paradigm shift in research +...

https://ojrd.biomedcentral.com/https://ojrd.biomedcentral.com/

#26: Issuing a Report with a Breast Density Assessment that is Phrased in the Singular, or is Neither Singular Nor Plural

https://www.fda.gov/radiation-emitting-products/regulations-mqsa/26-issuing-report-breast-density-assessment-phrased-singular-or-neither-singular-nor-plural?utm_medium=email&utm_source=govdelivery

Editorial p827 A commission on vector-borne infections The Lancet Infectious Diseases +...

https://www.thelancet.com/issue/S1473-3099(25)X0008-6 TheLancet.com will undergo maintenance on Sunday July 27th, from approximately, 5.30am to 1.30pm US EST. During this time, some of the site functionality will be paused, we apologise for the inconvenience.

Lay health worker-delivered case management for early episodes of psychosis in Bangkok, Thailand (Lay-CARE): a single-centre, pragmatic, randomised controlled trial

https://www.thelancet.com/journals/lansea/article/PIIS2772-3682(25)00088-5/fulltext?dgcid=hubspot_email_infocusalerts-psychiatry_feature&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz-9BVGMt8rlsLkKctiYPK0V6Uybz6EGOWbgrOZdKoA6qnpVmw-wffbv3C75KdTHYLVOChUFxfTcbAZN8IoicWjrTI7liDg&_hsmi=373110504&utm_content=372952145&utm_source=hs_email Editorial Drowning: a preventable crisis in the region The Lancet Regional Health – Southeast Asia https://www.thelancet.com/journals/lansea/issue/vol38nonull/PIIS2772-3682(25)X0006-8 TheLancet.com will undergo maintenance on Sunday July 27th, from approximately, 5.30am to 1.30pm US EST. During this time, some of the site functionality will be paused, we apologise for the inconvenience.

Thora Halldórsdóttir and Kristín Sigurdardottir on autism, ADHD, and autism-ADHD June 10, 2025 • The Lancet

https://thelancetchildadol.buzzsprout.com/1135472/episodes/17274673-thora-halldorsdottir-and-kristin-sigurdardottir-on-autism-adhd-and-autism-adhd?utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz--MOdGCqX0khp2TlYZjq8wzRDIfBu5NLO5dHiQY3li70sptImDH6NKZkmf-r_VifcJBvPWTPEb08GH_2anq447jTLjrug&_hsmi=373110504&utm_content=372952145&utm_source=hs_email

Long-acting oral weekly risperidone (LYN-005) for schizophrenia in the USA (STARLYNG-1): a multicentre, open-label, non-randomised phase 3 trial ++...

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00135-X/fulltext?dgcid=hubspot_email_infocusalerts-psychiatry_feature&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz-8idcQzGPjydfpqEs0VZq_thJNnOB7EF-9XmWxxrWgJpV3XjgXwrU1awouNqOTfGVKQ65SzH3vgvn8pE2fI-CnKwN8kkg&_hsmi=373110504&utm_content=372952145&utm_source=hs_email Editorial p475 Division and integration The Lancet Psychiatry https://www.thelancet.com/journals/lanpsy/issue/vol12no7/PIIS2215-0366(25)X0007-9 TheLancet.com will undergo maintenance on Sunday July 27th, from approximately, 5.30am to 1.30pm US EST. During this time, some of the site functionality will be paused, we apologise for the inconvenience.

Wenqing Li on transcriptome risk scores to decipher susceptibility genes for risk stratification of gastric cancer July 07, 2025 • The Lancet Group

https://ebiomedicine.buzzsprout.com/1809873/episodes/17429693-wenqing-li-on-transcriptome-risk-scores-to-decipher-susceptibility-genes-for-risk-stratification-of-gastric-cancer?utm_campaign=update-ebiom&utm_medium=email&_hsenc=p2ANqtz---f2hgkwm8tfq0P6AvYry18Ij13RAe5YZYJwpb1NHSSeP0C3H40106HxAGGBYKD39uMe9ZPNI6G5NOAiBT1N884zs2KQ&_hsmi=372659914&utm_content=372380424&utm_source=hs_email TheLancet.com will undergo maintenance on Sunday July 27th, from approximately, 5.30am to 1.30pm US EST. During this time, some of the site functionality will be paused, we apologise for the inconvenience.

A diet rich in fibre and vegetable protein during gestation and lactation shapes maternal immunity, intestinal microbiota and lipid metabolism

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00228-2/fulltext?dgcid=hubspot_update_feature_updatealerts_ebiom&utm_campaign=update-ebiom&utm_medium=email&_hsenc=p2ANqtz-9LqISl_9PIC8XeuZ_JyL4_LoPKUa0UN8UYZBVVKVJ4v4Aum3kecGp4P8PxY6ax7pK3UtWsFsFxc0cK4JOwQlO83Uk_eQ&_hsmi=372659914&utm_content=372380424&utm_source=hs_email TheLancet.com will undergo maintenance on Sunday July 27th, from approximately, 5.30am to 1.30pm US EST. During this time, some of the site functionality will be paused, we apologise for the inconvenience.

Phthalate exposure from plastics and cardiovascular disease: global estimates of attributable mortality and years life lost + +...

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00174-4/fulltext?dgcid=hubspot_update_feature_updatealerts_ebiom&utm_campaign=update-ebiom&utm_medium=email&_hsenc=p2ANqtz-9n9vRJiSvG1X3KOVaeL9adTxhV1rVQUko6h-OXIsGQhG4dnuhR3r5cKZ-dIwUKGLyMPwEmnRWEI5Jyf2R-9333PhHczg&_hsmi=372659914&utm_content=372380424&utm_source=hs_email Editorial The careful use of opioids and alternatives for pain management eBioMedicine https://www.thelancet.com/journals/ebiom/issue/vol117nonull/PIIS2352-3964(25)X0006-2 TheLancet.com will undergo maintenance on Sunday July 27th, from approximately, 5.30am to 1.30pm US EST. During this time, some of the site functionality will be paused, we apologise for the inconvenience.

Viewpoint: How Greta Thunberg’s doomsday degrowth messaging dangerously fanned hopelessness in younger generations Chelsea Follett | Cato Institute | July 25, 2025

https://geneticliteracyproject.org/2025/07/25/viewpoint-how-greta-thunbergs-doomsday-degrowth-messaging-dangerously-fanned-hopelessness-in-younger-generations/?mc_cid=14379e053b&mc_eid=b73600b7ac

Lab-grown meat labels: USDA finalizing rules on cell-cultivated meat amid protests Stephanie Gravalese | Food and Wine | July 24, 2025

https://geneticliteracyproject.org/2025/07/24/lab-grown-meat-labels-usda-finalizing-rules-on-cell-cultivated-meat-amid-protests/?mc_cid=14379e053b&mc_eid=b73600b7ac

Viewpoint: Agricultural gene editing should not go unregulated Lara Pacillo | Phys.org | July 24, 2025

https://geneticliteracyproject.org/2025/07/24/viewpoint-agricultural-gene-editing-should-not-go-unregulated/?mc_cid=14379e053b&mc_eid=b73600b7ac

Why are so many unapproved chemicals found in European-grown organic food? Food Safety Magazine | July 25, 2025

https://geneticliteracyproject.org/2025/07/25/why-are-so-many-unapproved-chemicals-found-in-european-grown-organic-food/?mc_cid=14379e053b&mc_eid=b73600b7ac

6 (relatively) recent examples proving that humans are still evolving Maria Faith Saligumba | Newsbreak | July 25, 2025

https://geneticliteracyproject.org/2025/07/25/6-relatively-recent-examples-proving-that-humans-are-still-evolving/

GLP podcast: Questionable COVID response fueled the MAHA movement. How should scientists respond? Cameron English, Liza Dunn | July 24, 2025

https://geneticliteracyproject.org/2025/07/24/glp-podcast-questionable-covid-response-fueled-the-maha-movement-how-should-scientists-respond/

Genetic tests can now predict childhood obesity, especially in whites—and could be employed to sharply curtail it University of Copenhagen | July 25, 2025

https://geneticliteracyproject.org/2025/07/25/genetic-tests-can-now-predict-childhood-obesity-especially-in-whites-and-could-be-employed-to-sharply-curtail-it/?mc_cid=14379e053b&mc_eid=b73600b7ac

Clinical Trials in CLL and MCL: Expert In-Depth Analysis Authors: Chan Cheah, MBBS, DMSc; Nirav N. Shah, MD; Jennifer A. Woyach, M

https://www.medscape.org/viewarticle/1002400?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250727-OUS-HONC-1002400-cta

Cushing’s Syndrome Treatment Research Highlights: ENDO 2024

https://checkrare.com/learning/p-cushings-syndrome-treatment-research-highlights-endo-2024/

FDA Investigating Death of 8-Year-Old Boy Who Received Elevidys

https://www.fda.gov/news-events/press-announcements/fda-investigating-death-8-year-old-boy-who-received-elevidys?utm_medium=email&utm_source=govdelivery FDA Investigating Death of 8-Year-Old Boy Who Received Elevidys The U.S. Food and Drug Administration is investigating the death of an 8-year-old boy who received Elevidys, a Sarepta Therapeutics gene therapy for Duchenne muscular dystrophy. The death occurred on June 7, 2025. The FDA has requested and received voluntary suspension of product distribution as it investigates the safety concerns. Elevidys is an adeno-associated virus vector-based gene therapy using Sarepta Therapeutics, Inc.’s AAVrh74 Platform Technology for the treatment of Duchenne muscular dystrophy. The product is administered as a single intravenous dose. Duchenne muscular dystrophy is a rare genetic condition characterized by progressive muscular weakness. The disease occurs due to a defective gene.

sábado, 26 de julio de 2025

Long sitting hours raise breast cancer odds for inactive obese women

https://www.news-medical.net/news/20250715/Long-sitting-hours-raise-breast-cancer-odds-for-inactive-obese-women.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_22_july_2025

Discovery of TAF1's role could revolutionize cancer treatment

https://www.news-medical.net/news/20250726/Discovery-of-TAF1s-role-could-revolutionize-cancer-treatment.aspx

Study reveals stigmatizing responses in LLMs for addiction-related queries / large language models (LLMs)

https://www.news-medical.net/news/20250726/Study-reveals-stigmatizing-responses-in-LLMs-for-addiction-related-queries.aspx

Research uncovers ME/CFS's systemic impact for targeted therapies +++

https://www.news-medical.net/news/20250726/Research-uncovers-MECFSs-systemic-impact-for-targeted-therapies.aspx New model predicts mRNA protein production, accelerating drug and vaccine discovery https://www.news-medical.net/news/20250726/New-model-predicts-mRNA-protein-production-accelerating-drug-and-vaccine-discovery.aspx Researchers pinpoint PRMT5 as a promising target for cancer drugs https://www.news-medical.net/news/20250726/Researchers-pinpoint-PRMT5-as-a-promising-target-for-cancer-drugs.aspx

Uncovering origins of autism, depression, Parkinson's in fetal brain

https://www.news-medical.net/news/20250726/Uncovering-origins-of-autism-depression-Parkinsons-in-fetal-brain.aspx

Editorial A better future through primary health care The Lancet Primary Care +...

https://www.thelancet.com/journals/lanprc/issue/vol1no1/PIIS3050-5143(25)X0002-9

Most Read Papers - Cancer Science & Oncogenesis

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_250725

New research identifies critical gene for treatment

https://www.news-medical.net/news/20250726/New-research-identifies-critical-gene-for-treatment.aspx

Editorial p543 Mental health in all policies The Lancet Psychiatry +...

https://www.thelancet.com/issue/S2215-0366(25)X0008-0

Rilzabrutinib in the Treatment of IgG4-Related Diseases John Stone, MD, Professor of Medicine at Harvard… +...

https://checkrare.com/

Designing the Optimal Care Plan for the Patient With Metastatic Castration-Resistant Prostate Cancer Authors: Bertrand Tombal, MD, PhD; Jonathan D. Tward, MD, PhD, FASTRO

https://www.medscape.org/viewarticle/1002397?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250726-OUS-HONC-1002397-cta

Linerixibat Reduces Itching in Patients with PBC By: Madaline Spencer|

https://checkrare.com/linerixibat-reduces-itching-in-patients-with-pbc/

Phase 3 GLISTEN Trial in Patients With Primary Biliary Cholangitis

https://checkrare.com/phase-3-glisten-trial-in-patients-with-primary-biliary-cholangitis/

Efficacy of Amivanatamab to Treat Left-Sided RAS/BRAF Wild-Type Metastatic Colorectal Cancer

https://checkrare.com/efficacy-of-amivanatamab-to-treat-left-sided-ras-braf-wild-type-metastatic-colorectal-cancer/

Editorial p625 Accelerating the path towards a cure for Parkinson's disease The Lancet Neurology +...

https://www.thelancet.com/journals/laneur/issue/vol24no8/PIIS1474-4422(25)X0008-9 Safety and efficacy of fenebrutinib in relapsing multiple sclerosis (FENopta): a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial and open-label extension study Amit Bar-OrMichal DufekHrvoje BudincevicJelena DrulovicMario HabekLe H Huaand others The Lancet NeurologyVol. 24No. 8p656–666 https://www.thelancet.com/collections/neurology?dgcid=hubspot_email_infocusalerts-neurology_feature&parent=001585&startPage=&ContentItemType=fla&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-9HtE8sxUgnm93GBIByy7KsqTc8yPeSLgZuyTXRoJEJI4h6BVDldWMh6DMp_jwbZc0xFRPiAjWQ92t6kZwLNN3h1rxG5g&_hsmi=373022104&utm_content=372951459&utm_source=hs_email Published: August, 2025

Fast Five Quiz: Assessing Early Breast Cancer in High-Risk Individuals Elwyn C. Cabebe, MD; Stefania Morganti, MD; Giuseppe Curigliano, MD, PhD; Maurie Markman, MD | July 24, 2025

https://reference.medscape.com/viewarticle/fast-five-quiz-assessing-early-breast-cancer-high-risk-2025a1000e5d?_gl=1*x30e39*_gcl_au*MTczMzE3MjAxOS4xNzQ2NzI0NDU0

Quickfire Updates on Gastric/GEJ Cancers: Latest Data in Perioperative Immunotherapy Authors: Geoffrey Ku, MD; Elizabeth Smyth, MD

https://www.medscape.org/viewarticle/1002710

Primary Central Nervous System Lymphoma Disease Education: The First Step to Advancing Outcomes Authors: Lakshmi Nayak, MD; Christopher R. D'Angelo, MD

https://www.medscape.org/viewarticle/primary-central-nervous-system-lymphoma-disease-education-2025a1000isn?page=1

Navigating Myelofibrosis and Anemia: Today's Challenges, Tomorrow’s Solutions Authors: John Mascarenhas, MD; Haifa Kathrin Al-Ali, MD; Francesco Passamonti, MD; Nona C. Baker, Dip.CounsMBACP

https://www.medscape.org/viewarticle/1002681

Personalized Care Is Pivotal: Navigating the Evolving Landscape for Advanced Urothelial Carcinoma Authors: Alison J. Birtle, MD, FRCP, FRCR, DipLCM; Philippe Barthélémy, MD, PhD; Enrique Grande, MD, PhD; Syed A. Hussain, MBBS, MSc, MD

https://www.medscape.org/viewarticle/1002453?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250725-OUS-HONC-1002453-cta

viernes, 25 de julio de 2025

For many Duchenne families, halt to gene therapy is heartbreak upon heartbreak A muscular dystrophy disease is devastating on its own, but a Sarepta treatment had offered hope

https://www.statnews.com/2025/07/24/duchenne-muscular-dystrophy-families-sarepta-elevydis/?utm_campaign=daily_recap&utm_medium=email&_hsenc=p2ANqtz--H-2H1QvT4N0uzTqBc_607GComNWYl6au7-16LDHbC_7UWd4uWjarZ5mm906sBrReRj8j_li75bgZvnIbVFFQhFcijTQ&_hsmi=372878121&utm_content=372878121&utm_source=hs_email

Hemophilia B: Gene Therapy Shows 5-Year Success Edited by Susan Ruel, PhD July 25, 2025

https://www.medscape.com/viewarticle/hemophilia-b-gene-therapy-shows-5-year-success-2025a1000jof

NIH Launches First Agency-Wide Plan for Autoimmune Disease Research Lucy Hicks July 25, 2025

https://www.medscape.com/viewarticle/nih-launches-first-agency-wide-plan-autoimmune-disease-2025a1000joi

Patient Portals and Teens: How Much Access Should Parents Have? Meg Barbor July 25, 2025

https://www.medscape.com/viewarticle/patient-portals-and-teens-how-much-access-should-parents-2025a1000joo

Breast Cancer Recurrence Low in Young Women Edited by Gargi Mukherjee July 25, 2025

https://www.medscape.com/viewarticle/breast-cancer-recurrence-low-young-women-2025a1000jpm

ASCO 2025 Recap: Melanoma Highlights on TILs, Toxicity, and Diet-Driven Outcomes Teresa Amaral, MD, PhD | July 24, 2025

https://www.medscape.com/viewarticle/asco-2025-recap-melanoma-highlights-tils-toxicity-and-diet-2025a1000id7

Emergence of Clade Ib Monkeypox Virus - Current State of Evidence Authors: Panayampalli S. Satheshkumar, PhD; Crystal M. Gigante, PhD; Placide Mbala-Kingebeni, MD, MSPH, PhD; Yoshinori Nakazawa, PhD; Mark Anderson, MD, MPH; Stephen Balinandi, MSc, PhD; Sophia Mulei, BS; James Fuller, PhD; Jennifer H. McQuiston, MS, DVM; Andrea M. McCollum, PhD; Christina L. Hutson, MS, PhD

https://www.medscape.org/viewarticle/1002705?sso=true&impID=7592286&uac=148436CN&src=wnl_tpal_250724_mscpedu

Decoding PD-L1 Scoring: Guiding Immunotherapy for Gastroesophageal Cancers Authors: Samuel J. Klempner, MD, FASCO; Matteo Fassan, MD, PhD; Mar Iglesias, MD

https://www.medscape.org/viewarticle/1002476?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250724-OUS-HONC-1002476-cta

Worms | Men’s Reproductive Health | Measuring Aging | Cleft Lip & Palate | Eye Doctor National Institutes of Health (NIH)

https://content.govdelivery.com/accounts/USNIH/bulletins/3ea6894?reqfrom=share

Is There a Role For GLP-1s in Psoriasis? Role of GLP-1 Drugs in Psoriasis Tx ++++++ ++

TRENDING ON PSORIASIS Re-defining Remission in Plaque Psoriasis https://www.medscape.com/viewarticle/experts-reach-consensus-defining-treatment-remission-plaque-2025a1000i0g?ecd=WNL_conf_Derm_Psoriasis-GRAPPA-NON-SPON_250725_MSCPEDIT_etid7592345&uac=148436CN&impID=7592345 Current and Future Uses for AI in Dermatology https://www.medscape.com/viewarticle/current-and-future-uses-ai-dermatology-experts-view-2025a1000f1k?ecd=WNL_conf_Derm_Psoriasis-GRAPPA-NON-SPON_250725_MSCPEDIT_etid7592345&uac=148436CN&impID=7592345 Drug Shows Sustained Improvement of GPP Symptoms https://www.medscape.com/viewarticle/spesolimab-provides-sustained-improvement-gpp-symptoms-and-2025a1000e5e?ecd=WNL_conf_Derm_Psoriasis-GRAPPA-NON-SPON_250725_MSCPEDIT_etid7592345&uac=148436CN&impID=7592345 Biologic Safety in Psoriasis Patients With Cancer https://www.medscape.com/viewarticle/il-23-inhibitors-appear-safe-psoriasis-cancer-2025a1000gho?ecd=WNL_conf_Derm_Psoriasis-GRAPPA-NON-SPON_250725_MSCPEDIT_etid7592345&uac=148436CN&impID=7592345 Rethinking Topical Therapy for Psoriasis https://www.medscape.com/viewarticle/1002116?ecd=WNL_conf_Derm_Psoriasis-GRAPPA-NON-SPON_250725_MSCPEDIT_etid7592345&uac=148436CN&impID=7592345 Volume, Not Price, Drives Derm Drug Costs https://www.medscape.com/viewarticle/volume-not-price-fueling-rise-part-d-specialty-derm-drug-2025a1000j39?ecd=WNL_conf_Derm_Psoriasis-GRAPPA-NON-SPON_250725_MSCPEDIT_etid7592345&uac=148436CN&impID=7592345 CLINICAL RESOURCES What Do You Know About Generalized Pustular Psoriasis? Test Your Knowledge https://reference.medscape.com/viewarticle/fast-five-quiz-what-do-you-know-about-generalized-pustular-2025a1000bai?ecd=WNL_conf_Derm_Psoriasis-GRAPPA-NON-SPON_250725_MSCPEDIT_etid7592345&uac=148436CN&impID=7592345 Painful, Rupturing Lesions in a 40-Year-Old Man: What is Your Dx? https://reference.medscape.com/viewarticle/painful-rupturing-lesions-40-year-old-man-2025a1000f4s?ecd=WNL_conf_Derm_Psoriasis-GRAPPA-NON-SPON_250725_MSCPEDIT_etid7592345&uac=148436CN&impID=7592345

Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) 2025 Annual Meeting and Trainee Symposium

https://www.medscape.com/viewcollection/37851?ecd=WNL_conf_Derm_Psoriasis-GRAPPA-NON-SPON_250725_MSCPEDIT_etid7592345&uac=148436CN&impID=7592345

FOOD MATTERS

Food Matters By Ivanhoe Broadcast News on July 25, 2025 https://www.ivanhoe.com/family-health/food-matters/

A NEW THERAPY FOR MELANOMA: WHEN ALL ELSE FAILS

A New Therapy for Melanoma: When All Else Fails By Ivanhoe Broadcast News on July 21, 2025 https://www.ivanhoe.com/family-health/a-new-therapy-for-melanoma-when-all-else-fails/

SCIENTISTS DISCOVER NEW DANGERS OF MICROPLASTICS

Scientists Discover New Dangers of Microplastics By Ivanhoe Broadcast News on July 22, 2025 https://www.ivanhoe.com/family-health/scientists-discover-new-dangers-of-microplastics/

REWIRING RECOVERY: VIVISTIM FOR STROKE SURVIVORS

Rewiring Recovery: Vivistim for Stroke Survivors By Ivanhoe Broadcast News on July 24, 2025 https://www.ivanhoe.com/family-health/rewiring-recovery-vivistim-for-stroke-survivors/

HELPING YOUR CHILD BUILD THEIR RESILIENCE MUSCLE

Helping Your Child Build Their Resilience Muscle By Ivanhoe Broadcast News on August 1, 2025 https://www.ivanhoe.com/?p=35782&preview=1&_ppp=1a4f41bd38

IDEAS FOR US: ECO-ACTION EMPOWERING PEOPLE

IDEAS For Us: Eco-Action Empowering People By Ivanhoe Broadcast News on July 31, 2025 https://www.ivanhoe.com/?p=35780&preview=1&_ppp=1dab57719d

WHEN HEAT TURNS DEADLY: WHAT PARENTS NEED TO KNOW

When Heat Turns Deadly: What Parents Need to Know By Ivanhoe Broadcast News on July 30, 2025 https://www.ivanhoe.com/?p=35777&preview=1&_ppp=01b139beba

PLANTING PURPOSE & CULTIVATING CONNECTION

Planting Purpose & Cultivating Connection By Ivanhoe Broadcast News on July 29, 2025 https://www.ivanhoe.com/?p=35774&preview=1&_ppp=6af5626602

SPOTTING PROSTATE CANCER EARLIER

Spotting Prostate Cancer Earlier By Ivanhoe Broadcast News on July 28, 2025 https://www.ivanhoe.com/?p=35752&preview=1&_ppp=d73ab44229

jueves, 24 de julio de 2025

Digging into the past: What ancient proteins say about real medieval meals

https://www.news-medical.net/news/20250724/Digging-into-the-past-What-ancient-proteins-say-about-real-medieval-meals.aspx

Low-gluten diets disrupt gut health by depleting key bacteria

https://www.news-medical.net/news/20250724/Low-gluten-diets-disrupt-gut-health-by-depleting-key-bacteria.aspx Scientists uncover how long-term gluten reduction, often seen as a health boost, can actually upset gut balance, strip away key microbes, and trigger ethanol build-up tied to inflammation and metabolic risks.

AGS releases new guide for safer medication alternatives in older adults

https://www.news-medical.net/news/20250724/AGS-releases-new-guide-for-safer-medication-alternatives-in-older-adults.aspx

Innovative immunotherapy trial opens for newly-diagnosed glioblastoma patients

https://www.news-medical.net/news/20250724/Innovative-immunotherapy-trial-opens-for-newly-diagnosed-glioblastoma-patients.aspx

Scientists discover neuron-like communication system in the gut

https://www.news-medical.net/news/20250724/Scientists-discover-neuron-like-communication-system-in-the-gut.aspx

Walking 7,000 steps per day associated with reductions in risk of several serious health problems

https://www.news-medical.net/news/20250724/Walking-7000-steps-per-day-associated-with-reductions-in-risk-of-several-serious-health-problems.aspx

Ibogaine treatment shows major breakthrough for veterans with brain injuries

https://www.news-medical.net/news/20250724/Ibogaine-treatment-shows-major-breakthrough-for-veterans-with-brain-injuries.aspx

Ketamine's antidepressant effects involve the brain's opioid system

https://www.news-medical.net/news/20250724/Ketamines-antidepressant-effects-involve-the-brains-opioid-system.aspx

Hendra Virus: An Emerging Zoonotic Threat in a Warming World

https://www.news-medical.net/health/Hendra-Virus-An-Emerging-Zoonotic-Threat-in-a-Warming-World.aspx

Sesame Oil Health Benefits: Examining the Diverse Roles of Lignans and Lipids

https://www.news-medical.net/health/Sesame-Oil-Health-Benefits-Examining-the-Diverse-Roles-of-Lignans-and-Lipids.aspx

What Are Nootropics? Mechanisms, Efficacy, and Safety of Cognitive Enhancers

https://www.news-medical.net/health/What-Are-Nootropics-Mechanisms-Efficacy-and-Safety-of-Cognitive-Enhancers.aspx

Study reveals pandemic life made brains age faster, even without catching COVID-19

https://www.news-medical.net/news/20250723/Study-reveals-pandemic-life-made-brains-age-faster-even-without-catching-COVID-19.aspx New research reveals that social isolation and stress during the COVID-19 pandemic accelerated the aging of the brains of older adults, regardless of whether they contracted the virus, highlighting the urgent need for protective strategies beyond infection control.

HHS, FDA and USDA Address the Health Risks of Ultra-Processed Foods

https://www.fda.gov/news-events/press-announcements/hhs-fda-and-usda-address-health-risks-ultra-processed-foods?utm_medium=email&utm_source=govdelivery

Use of Anti-Amyloid Therapies in the Setting of Mild Cognitive Impairment: A Patient-Clinician Vignette Authors: B. Joy Snider, MD, PhD

https://www.medscape.org/viewarticle/1002553_sidebar9?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_250724-ES_LANG-NEUR-1002553-cta

Guiding Our Patient's Path: Managing First Relapse in Diffuse Large B-Cell Lymphoma Outside of CAR Ts Authors: Wendy Osborne, MBBS (Hons), MRCP, FRCPath; Natacha Bolaños; Gareth Gregory, MBBS, PhD; Gilles Salles, MD, PhD

https://www.medscape.org/viewarticle/1002120_sidebar9?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_250724-ES_LANG-HONC-1002120-cta

Taurine: From Energy Drink Darling to Cancer Suspect? Anke Brodmerkel July 24, 2025

https://www.medscape.com/viewarticle/taurine-energy-drink-darling-cancer-suspect-2025a1000jkx

DLBCL: FDA Rejects BLA for Second-Line Glofitamab Combo Sharon Worcester July 24, 2025

https://www.medscape.com/viewarticle/dlbcl-fda-rejects-bla-second-line-glofitamab-combo-2025a1000jm4

Rare Disease Focus: Heart Disease +++ +++ +

CLINICAL PERSPECTIVES Marfan Syndrome: Diagnosis and Management https://checkrare.com/marfan-syndrome-diagnosis-and-management/ David Liang, MD, PhD, Cardiologist at Hoag Hospital, discusses the diagnosis and management of Marfan syndrome. Evolving Policy Landscapes for Rare Disease Access https://checkrare.com/evolving-policy-landscapes-for-rare-disease-access/ Deb Jennings, Head of North America Patient Services Operations at Kyowa Kirin, discusses evolving policy landscapes for rare disease access. The Role of Mental Health in Rare Disease Patient Outcomes https://checkrare.com/the-role-of-mental-health-in-rare-disease-patient-outcomes/ Sumira Riaz, PhD, Health Psychologist & Patient Engagement Consultant at Unboxed Psychology, discusses the role of mental health in rare disease patient outcomes. Disease Severity and Progression in Patients With ENPP1 Deficiency https://checkrare.com/disease-severity-and-progression-in-patients-with-enpp1-deficiency/ Matt Winton, PhD, Senior Vice President and Chief Operating Officer of Inozyme Pharma, discusses results from an analysis characterizing disease severity and progression in patients with ENPP1 deficiency. The Undiagnosed Disease Network https://checkrare.com/the-undiagnosed-disease-network/ Kimberly LeBlanc, Genetic Counselor, Director of the Undiagnosed Diseases Network (UDN) Coordinating Center at Harvard Medical School, discusses approaching variants of uncertain significance in rare diseases. Ethical Concerns in Rare Diseases and Expanded Access Programs https://checkrare.com/ethical-concerns-in-rare-diseases-and-expanded-access-programs/ Alison Bateman-House, PhD, Assistant Professor Division of Medical Ethics at NYU Grossman School of Medicine, discusses ethical concerns in rare diseases and expanded access programs. The Diversity of Patient Advocacy Group Initiatives https://checkrare.com/the-diversity-of-patient-advocacy-group-initiatives/ Connie Lee, PsyD, Chief Executive Officer of Alliance to Cure Cavernous Malformations, discusses cerebral cavernous malformation (CMM) and the diversity of patient advocacy group initiatives.

The global landscape and development pipeline for childhood cancer medicines: a comprehensive analysis with dashboard generation +...

https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(25)00142-7/abstract?utm_campaign=update-lanchi&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanchi&_hsenc=p2ANqtz-__QKaBPTCgE5OrCNkibfyad1p9G1PjyPQ3xANjT0q_G9ndQi_P983dKRTwwC7AVlBtODsIDeaiCq8bRjIjvdbUaG9vgw&_hsmi=372642248&utm_content=372379837&utm_source=hs_email Editorial p519 Research-driven neonatology for equitable neonatal health The Lancet Child & Adolescent Health https://www.thelancet.com/journals/lanchi/issue/vol9no8/PIIS2352-4642(25)X0008-0 The Lancet Child & Adolescent Health Commission on the future of neonatology https://www.thelancet.com/commissions-do/future-neonatology?dgcid=hubspot_update_feature_lanchineonatalrd25&utm_campaign=update-lanchi&utm_medium=email&_hsenc=p2ANqtz-8n6JVObgK59dJ1sqVxJJjBpoWuGpXqt1xrgy8aNSazIUzPMD2aei0GHlxoLu8hGZ63pdJWw3Ecw5z58HM8iGIprPztWg&_hsmi=372642248&utm_content=372379837&utm_source=hs_email Trends and predictions to 2030 in demographic structures and metabolic health for children and adolescents in China: analysis of national school health surveys from 2000 to 2019 https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(25)00140-3/abstract?utm_campaign=update-lanchi&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanchi&_hsenc=p2ANqtz-_oV3jp8EXDg9zsj_IndINFHE4gjBmWJ1Y-3gT6Y3p7Ayvp7e7eiuHWEf0plC_9NK8Efds5-5b4dpfZZrzNVEIGVFQeGA&_hsmi=372642248&utm_content=372379837&utm_source=hs_email

A commission on vector-borne infections The Lancet Infectious Diseases +...

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00430-X/fulltext?dgcid=raven_jbs_etoc_email Issue cover for Volume 25, Issue 8 Aug 2025 Volume 25Number 8p827-946, e439-e490 https://www.thelancet.com/journals/laninf/issue/vol25no8/PIIS1473-3099(25)X0008-6 Immunogenicity and safety of an Escherichia coli-produced bivalent human papillomavirus vaccine (Cecolin) in girls aged 9–14 years in Ghana and Bangladesh: a randomised, controlled, open-label, non-inferiority, phase 3 trial https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00031-3/fulltext?dcig=raven_jbs_etoc_feature_laninf

miércoles, 23 de julio de 2025

'Western diet' blamed for growing risk of GI cancers among young adults By Ashley J. DiMella Fox News Published July 16, 2025 8:36am EDT

'Western diet' blamed for growing risk of GI cancers among young adults Processed meats, sugary drinks and refined grains identified as potential risk factors Ashley J. DiMella By Ashley J. DiMella Fox News Published July 16, 2025 8:36am EDT https://www.foxnews.com/health/western-diet-blamed-growing-risk-gi-cancers-among-young-adults

Texas psychiatrist reveals mental health challenges facing flood disaster survivors By Rachel Wolf Fox News Published July 16, 2025 12:19pm EDT

Texas psychiatrist reveals mental health challenges facing flood disaster survivors 'The reality for these families is that once the camera crews are gone and once the aid organizations are packing up, they’re still going to be living with the repercussions of this,' Dr. Browne said Rachel Wolf By Rachel Wolf Fox News Published July 16, 2025 12:19pm EDT https://www.foxnews.com/health/texas-psychiatrist-reveals-mental-health-challenges-facing-flood-disaster-survivors

Here's what marijuana really does to the developing brain, according to a psychiatrist By Angelica Stabile Fox News Published July 18, 2025 2:58pm EDT

Here's what marijuana really does to the developing brain, according to a psychiatrist Cognitive specialist Dr. Amen warns that cannabis can age the brain and cause mental health issues Angelica Stabile By Angelica Stabile Fox News Published July 18, 2025 2:58pm EDT https://www.foxnews.com/health/heres-what-marijuana-really-does-developing-brain-according-psychiatrist

Alzheimer's risk could rise with specific sleep pattern, experts warn By Angelica Stabile Fox News Published July 21, 2025 5:00am EDT

Alzheimer's risk could rise with specific sleep pattern, experts warn Delayed REM sleep may indicate cognitive decline, study suggests Angelica Stabile By Angelica Stabile Fox News Published July 21, 2025 5:00am EDT https://www.foxnews.com/health/alzheimers-risk-could-rise-specific-sleep-pattern-experts-warn

Higher cancer rates linked to WWII radioactive waste in Midwestern creek By Angelica Stabile Fox News Published July 22, 2025 5:07pm EDT

Higher cancer rates linked to WWII radioactive waste in Midwestern creek Missouri's Coldwater Creek leaves lasting health legacy for those who grew up there Angelica Stabile By Angelica Stabile Fox News Published July 22, 2025 5:07pm EDT https://www.foxnews.com/health/higher-cancer-rates-linked-wwii-radioactive-waste-midwestern-creek

Children's National Hospital in DC to end gender transition medical interventions By Danielle Wallace Fox News Published July 21, 2025 8:57am EDT

Children's National Hospital in DC to end gender transition medical interventions Children's National cites 'escalating legal and regulatory risks' as Justice Department investigates pediatric transgender procedures Danielle Wallace By Danielle Wallace Fox News Published July 21, 2025 8:57am EDT https://www.foxnews.com/health/childrens-national-hospital-dc-end-gender-transition-medical-interventions

Experts reveal 5-step approach to a healthier gut and stronger immunity By Amy McGorry Fox News Published July 17, 2025 5:00am EDT

Experts reveal 5-step approach to a healthier gut and stronger immunity Medical experts reveal how the '5R' plan can boost immunity and reduce inflammation By Amy McGorry Fox News Published July 17, 2025 5:00am EDT https://www.foxnews.com/health/experts-reveal-5-step-approach-healthier-gut-stronger-immunity

Eating foods in this order could help with weight loss and blood sugar, experts say By Amy McGorry Fox News Published July 20, 2025 4:23pm EDT

Eating foods in this order could help with weight loss and blood sugar, experts say ‘Meal sequencing’ technique has been shown to benefit those with diabetes By Amy McGorry Fox News Published July 20, 2025 4:23pm EDT https://www.foxnews.com/health/eating-foods-order-could-help-weight-loss-blood-sugar-experts-say

Mitochondria and health

https://www.nih.gov/news-events/nih-research-matters/mitochondria-health

E21 Inclusion of Pregnant and Breastfeeding Women in Clinical Trials Draft Guidance for Industry July 2025

https://www.fda.gov/regulatory-information/search-fda-guidance-documents/e21-inclusion-pregnant-and-breastfeeding-women-clinical-trials?utm_medium=email&utm_source=govdelivery Download the draft guidance document (PDF, 430KB) https://www.fda.gov/media/187755/download?utm_medium=email&utm_source=govdelivery

Man's deadly brain cancer tumor disappears after experimental drug trial Two years after treatment with ipilimumab, patient shows no signs of glioblastoma Melissa Rudy By Melissa Rudy Fox News Published July 22, 2025 5:00am EDT

Man's deadly brain cancer tumor disappears after experimental drug trial Two years after treatment with ipilimumab, patient shows no signs of glioblastoma Melissa Rudy By Melissa Rudy Fox News Published July 22, 2025 5:00am EDT https://www.foxnews.com/health/mans-deadly-brain-cancer-tumor-disappears-after-experimental-drug-trial

Never enter an MRI machine with any of these hazardous items, experts warn New York man's death highlights critical MRI safety protocols Angelica Stabile By Angelica Stabile Fox News Published July 21, 2025 3:27pm EDT

Never enter an MRI machine with any of these hazardous items, experts warn New York man's death highlights critical MRI safety protocols Angelica Stabile By Angelica Stabile Fox News Published July 21, 2025 3:27pm EDT https://www.foxnews.com/health/never-enter-mri-machine-any-hazardous-items-experts-warn?lid=zncn76nmijkl

Detecting menstrual blood biomarkers directly on sanitary pads Point-of-care tests that detect biomarkers from menstrual blood can enable broader access to disease monitoring and diagnosis.

https://www.drugdiscoverynews.com/detecting-menstrual-blood-biomarkers-directly-on-sanitary-pads-16510?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--WQBfgRV24TXBjtPOBn3_FqidrhMqyWRhBBcSR-2P8YNoHOcIFwWfEmcg9JXppNnTZ6_pURzGe901KGoJbGaOJbWPnlg&_hsmi=372603124&utm_content=372603124&utm_source=hs_email

Is RFK. Jr. protecting or endangering pregnant women by blocking the CDC from recommending COVID vaccines? Jackie Fortiér | July 23, 2025

https://geneticliteracyproject.org/2025/07/23/is-rfk-jr-protecting-or-endangering-pregnant-women-by-blocking-the-cdc-from-recommending-covid-vaccines/?mc_cid=1bec13e719&mc_eid=b73600b7ac

The impact of living with a rare disease: barriers and enablers of independent living and social participation +++

https://www.eurordis.org/publications/rb-dailylife-report/ EURORDIS responds to European Commission’s proposed 2028-34 budget July 2025 17 July 2025, Brussels – The European Commission has unveiled its long-term budget proposal for the 2028–2034 Multiannual Financial Framework (MFF). The proposal sets out the Union’s roughly €1.8 trillion budget and spending priorities for the seven-year period, including investments in competitiveness, social cohesion, public health, and research. https://www.eurordis.org/eurordis-responds-to-eu-commissions-proposed-2028-34-budget/ Recognising the disabilities of those living with rare diseases July 2025 Between July and September 2024, EURORDIS–Rare Diseases Europe’s Rare Barometer programme carried out one of the widest-reaching surveys to date on the intersection between rare diseases and disability. https://www.eurordis.org/recognising-rare-disease-disabilities/

Chronic Inflammatory Demyelinating Polyradiculoneuropathy: What to Expect From New Treatments Authors: Jeffrey A. Allen, MD; Thomas Harbo, MD, PhD

https://www.medscape.org/viewarticle/1002649_sidebar9?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_250723-1002649_ES_NEUR

Women’s Health, Unstuck Where Broad Institute of MIT and Harvard 415 Main Street Cambridge, MA 02142 When Monday, August 4, 2025 5:30 p.m. - 8:20 p.m. GMT-3

https://www.statnews.com/event/womens-health-unstuck/?utm_campaign=womens-health-unstuck-Aug25&utm_medium=email&_hsenc=p2ANqtz--Vcaieu4DC1eQOCJv1ce9QuClx-5N1o8JDjLRPV30f2wD-Q9n08b6JC10qA6EekRonOwYsidx1wB35fVV8n8_8zrB6bA&_hsmi=372665305&utm_source=events_nns

Editorial Whole-genome sequencing for every newborn in the UK: promise and practicalities eClinicalMedicine +...

https://www.thelancet.com/journals/eclinm/issue/vol85nonull/PIIS2589-5370(25)X0006-7

Editorial p701 Exercise for colon cancer: from supportive care to therapy The Lancet Gastroenterology & Hepatology +...

https://www.thelancet.com/journals/langas/issue/vol10no8/PIIS2468-1253(25)X0007-8

Beyond Baby KJ: Next Steps in Manufacturing Genome Editing Cures Wednesday, July 30, 2025 9:00 am PT, 12:00 pm ET, 18:00 CEST

https://www.genengnews.com/multimedia/beyond-baby-kj-next-steps-in-manufacturing-genome-editing-cures/?utm_campaign=15735301-GEN_GEN_Live_20250730&utm_medium=email&_hsenc=p2ANqtz-_xvOAUKG2p4KdRdbi2NsfE8bof_3qboBP99tJfi8mWve8-JVTuRpbYdxUpvspPy11laT-IBX4khaJicE_RjumSQeD6IQ&_hsmi=372453060&utm_content=372400580&utm_source=hs_email Last month, for the first time, a baby with a rare genetic disorder known as “Baby KJ” was treated with a gene-editing therapy tailored to his rare mutation. The milestone made headlines—and marked a win for the genome editing field, offering new promise for the future of genomic medicine. But there is another layer to the story: how the treatment was manufactured. Developing a single, personalized therapy required a coordinated sprint from teams at IDT, Aldevron, and Danaher, working under intense pressure to produce the gene-editing payload and its delivery system. Now, the real challenge lies ahead—delivering treatments like this to more patients. On this GEN Live, we take a close look at the work behind this successful treatment and perhaps more importantly, we explore how this can be done on a larger scale in the future. We will discuss the challenges that lie ahead, including scale and cost, and how some companies are thinking about solving those.

martes, 22 de julio de 2025

Weight regain observed in patients after ending obesity drug treatment

https://www.news-medical.net/news/20250722/Weight-regain-observed-in-patients-after-ending-obesity-drug-treatment.aspx

Extreme childhood obesity drives liver and diabetes risks

https://www.news-medical.net/news/20250722/Extreme-childhood-obesity-drives-liver-and-diabetes-risks.aspx

Mount Sinai researcher uncovers how brain and body interact in aging and depression

https://www.news-medical.net/news/20250722/Mount-Sinai-researcher-uncovers-how-brain-and-body-interact-in-aging-and-depression.aspx

Viewpoint: MAHA supporters and anti-vaxxers are spreading chemophobia through the mainstream Janna Mandell | Beauty Matter | July 22, 2025

https://geneticliteracyproject.org/2025/07/22/viewpoint-maha-supporters-and-anti-vaxxers-are-spreading-chemophobia-through-the-mainstream/?mc_cid=514cd8885c&mc_eid=b73600b7ac

GLP Spaces on X: Misinfo from the mainstream. Hypocritical pediatricians blast RFK Jr.’s anti-vaxx stance while flouting consensus on GMOs Cameron English, Jon Entine, Liza Dunn | July 22, 2025

https://geneticliteracyproject.org/2025/07/22/glp-spaces-on-x-misinfo-from-the-mainstream-hypocritical-pediatricians-blast-rfk-jr-s-anti-vaxx-stance-while-flouting-consensus-on-gmos/?mc_cid=514cd8885c&mc_eid=b73600b7ac

National Cancer Institute—world’s premier cancer research center—victim of RFK’s cuts and chaos agenda Arthur Allen, Rachana Pradhan | July 22, 2025

https://geneticliteracyproject.org/2025/07/22/national-cancer-institute-worlds-premier-cancer-research-center-victim-of-rfks-cuts-and-chaos-agenda/?mc_cid=514cd8885c&mc_eid=b73600b7ac

Myelofibrosis-Associated Anemia: Burden, Management, and Future Directions Authors: Francesca Palandri, MD; Jean-Jacques Kiladjian, MD, PhD; Jon Mathias

https://www.medscape.org/viewarticle/1002370?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250721-OUS-HONC-1002370-cta

Advancing Patient-Centered Care in mCRPC: Exploring PARP Inhibitor Combinations Authors: Neeraj Agarwal, MD, FASCO; Karim Fizazi, MD, PhD

https://www.medscape.org/viewarticle/1002353?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250722-OUS-HONC-1002353-cta

The evolving treatment landscape in Still's disease The Lancet Rheumatology + + +...

https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(25)00192-4/fulltext?dgcid=raven_jbs_etoc_email Aug 2025 Volume 7Number 8e521-e590 https://www.thelancet.com/journals/lanrhe/issue/vol7no8/PIIS2665-9913(25)X0008-4 Sarilumab in relapsing polymyalgia rheumatica: patient-reported outcomes from a phase 3, double-blind, randomised controlled trial https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(25)00041-4/abstract?dgcid=raven_jbs_etoc_feature_lanrhe

Virtual Simulations: Managing the Patient With HR+/HER2- Early Breast Cancer Through a Multidisciplinary Approach Authors: Manali Bhave, MD; Jane Meisel, MD

https://www.medscape.org/viewarticle/1002474?sso=true&uac=148436CN&src=mkmcmr_driv_psims_mscpedu_250722-OUS-HONC-1002474-cta

Nasopharyngeal Carcinoma in Clinical Context: Maximizing Treatment Outcomes

https://www.medscape.org/advances/enhancing-npc-care-2025a100047d?src=ban_driv_250331_mscpedu_420171.01_ace

IMPACT CLL & MCL: IMPlementing Advances in Cancer Treatment for Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma

https://www.medscape.org/advances/impact-cll-mcl-2025a1000ar6?src=ban_driv_250527_mscpedu_421115.01_ace

Breast Growth: Cancer or Coincidence in 42-Year-Old? Wolfgang Paik Medscape UK July 21, 2025

https://www.medscape.com/viewarticle/breast-growth-cancer-or-coincidence-42-year-old-2025a1000j6h

Rapid Review: Bladder Cancer Kyle A. Richards, MD | July 22, 2025

https://reference.medscape.com/viewarticle/bladder-cancer-rapid-review-2025a1000itv?_gl=1*11qnudb*_gcl_au*MTczMzE3MjAxOS4xNzQ2NzI0NDU0

Air Pollution Linked to Increased CNS Tumor Risk Edited by Anushree Chaphalkar July 22, 2025

https://www.medscape.com/viewarticle/air-pollution-linked-increased-cns-tumor-risk-2025a1000jbr

QOL Deserves More Than a Footnote in Cancer Trials Cristina Ferrario July 22, 2025

https://www.medscape.com/viewarticle/qol-deserves-more-than-footnote-cancer-trials-2025a1000jbv

Cancer Risk in Mycophenolate-Treated Patients Differs by Indication Edited by Deepa Varma July 22, 2025

https://www.medscape.com/viewarticle/cancer-risk-mycophenolate-treated-patients-differs-2025a1000jbi

Gas vs Charcoal: Which Barbecue Causes Less Harm? Nathalie Haidlauf July 22, 2025

https://www.medscape.com/viewarticle/gas-vs-charcoal-which-barbecue-causes-less-harm-2025a1000jef

FDA Advisory Panel Votes NO on Belantamab for Myeloma Sharon Worcester July 21, 2025

https://www.medscape.com/viewarticle/fda-advisory-panel-votes-no-belantamab-myeloma-2025a1000j6y

Could It Be Progressive Familial Intrahepatic Cholestasis? A Diagnostic Journey Authors: Lorenzo D'Antiga, MD; Jesus Quintero Bernabeu, MD, PhD; Giuseppe Indolfi, MD, PhD; Richard J. Thompson, MD, PhD

https://www.medscape.org/viewarticle/1002612_sidebar3

lunes, 21 de julio de 2025

Insurance-Survival Gap Growing in Immunotherapy Era Edited by Gargi Mukherjee July 21, 2025 ++++

https://www.medscape.com/viewarticle/insurance-survival-gap-growing-immunotherapy-era-2025a1000j7e Safe to Skip Postop Radioiodine in Most Low-Risk Thyroid Cancers Edited by Gargi Mukherjee https://www.medscape.com/viewarticle/safe-skip-postop-radioiodine-most-low-risk-thyroid-cancers-2025a1000j7z July 21, 2025 FDA Advisory Panel Votes NO on Belantamab for Myeloma Sharon Worcester https://www.medscape.com/viewarticle/fda-advisory-panel-votes-no-belantamab-myeloma-2025a1000j6y July 21, 2025 The Impact of Prevention, Screening, and Treatment on Cancer Death Reduction Maurie Markman, MD https://www.medscape.com/viewarticle/impact-prevention-screening-and-treatment-cancer-death-2025a1000i47 | July 21, 2025

ILD Associated With Increased Risk for Lung Cancer Edited by Gargi Mukherjee July 21, 2025

https://www.medscape.com/viewarticle/ild-associated-increased-risk-lung-cancer-2025a1000j84

Total Neoadjuvant Therapy Shows Consistent Efficacy Across Different Regimens in Locally Advanced Rectal Cancer Edited by Gargi Mukherjee Medscape UK article logo July 21, 2025Total Neoadjuvant Therapy Shows Consistent Efficacy Across Different Regimens in Locally Advanced Rectal Cancer Edited by Gargi Mukherjee Medscape UK July 21, 2025

https://www.medscape.com/viewarticle/total-neoadjuvant-therapy-shows-consistent-efficacy-across-2025a1000iye

Post-traumatic stress disorder in older adults: a global collaboration on setting the future research agenda +...

https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(25)00039-X/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhl&utm_campaign=update-lanhl&utm_medium=email&_hsenc=p2ANqtz-_AUFdG_mUV75DdMdCWzHm2ota1-bj-t6qvI-v8ralXQFgP9dB2bnr3zdgc-bU2VOVR_pm2DSp4t5kIpsahKl4YXQG3LA&_hsmi=372138574&utm_content=371908342&utm_source=hs_email Editorial Adult social care: insufficient funding and financial pressures The Lancet Healthy Longevity https://www.thelancet.com/journals/lanhl/issue/vol6no6/PIIS2666-7568(25)X0007-6

Blocking GAPDH aggregation protects brain cells and opens new path for stroke therapy

https://www.news-medical.net/news/20250720/Blocking-GAPDH-aggregation-protects-brain-cells-and-opens-new-path-for-stroke-therapy.aspx A novel study reveals that targeting a single protein’s aggregation can dramatically reduce brain injury after stroke, potentially transforming how acute ischemic strokes are treated.

Novel polysaccharide from Albizzia julibrissin shows promise against pancreatic cancer

https://www.news-medical.net/news/20250721/Novel-polysaccharide-from-Albizzia-julibrissin-shows-promise-against-pancreatic-cancer.aspx

Can probiotics help you sleep better?

Could the key to better sleep and brighter mood lie in your gut? New research suggests probiotic supplements may safely ease insomnia and depressive symptoms, but more studies are needed to pinpoint who benefits most. https://www.news-medical.net/news/20250720/Can-probiotics-help-you-sleep-better.aspx

Erythritol alters brain vessel function and may raise stroke risk

Scientists show how a common zero-calorie sweetener found in many diet drinks may harm the brain's vascular system by increasing oxidative stress and impairing vital blood vessel functions. https://www.news-medical.net/news/20250721/Erythritol-alters-brain-vessel-function-and-may-raise-stroke-risk.aspx

Study uncovers a specialized gut-brain pathway for glucose sensing

https://www.news-medical.net/news/20250721/Study-uncovers-a-specialized-gut-brain-pathway-for-glucose-sensing.aspx

Meat hummus lowers microbes and raises nutrition

https://www.news-medical.net/news/20250721/Meat-hummus-lowers-microbes-and-raises-nutrition.aspx Scientists show that lamb-infused hummus packs more protein, iron, and flavor while staying fresher, offering flexitarians and athletes a nutrient-rich twist on the classic dip.

Gut microbes synthesize a potential antidiabetic target Targeting a gut microbial enzyme could potentially improve treatment for type 2 diabetes.

https://www.drugdiscoverynews.com/gut-microbes-synthesize-a-potential-antidiabetic-target-15872?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--4OmHMMBVdouBYkhI5I6ECEjoDCSVF5uOj5ZPORc1Pf7cBbsRXdcTOOHApm6YbuKvnR-dpqErkceGUDVSic4qZvarJEw&_hsmi=372197073&utm_content=372197073&utm_source=hs_email

A gut microbe for curbing sugar cravings Targeting a gut bacterial species or its metabolites could potentially improve diabetes management by reducing sugar preferences.

https://www.drugdiscoverynews.com/a-gut-microbe-for-curbing-sugar-cravings-16241?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-8vwZ8rSpuCV1aiG2Kd2ovS6Lz8Q3F_67PEGFGRu3Kb8pV8Clu7ox7YbM_nzq5mqm-YqZ6zmv7hoACg7dPBWC9JYRZVsA&_hsmi=372197073&utm_content=372197073&utm_source=hs_email

Proteome analysis reveals personalized diabetes signatures Researchers showed that insulin resistance exists on a spectrum among diabetics and healthy controls.

https://www.drugdiscoverynews.com/proteome-analysis-reveals-personalized-diabetes-signatures-16502?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-8idn5WbUTvCV8P5kurmPdBxRJSYNOMqLFatPx7CoFW4wh8tkhXvb8TY7vJYdD3cYwg8bzKSypsSwkjMDF41sjBw5yZPg&_hsmi=372197073&utm_content=372197073&utm_source=hs_email

Alkermes drug helped narcolepsy patients stay awake in Phase 2 trial Company says results suggest treatment could also help improve fatigue and cognition

https://www.statnews.com/2025/07/21/alkermes-drug-narcolepsy-alixorexton-results/

My mother refused treatment for her breast cancer. Her doctors should have respected her choice Instead, they dismissed her — and criticized me

https://www.statnews.com/2025/07/21/breast-cancer-refusing-treatment-palliative-care-hospice-insurance/

Transforming women's health, empowerment, and gender equality with digital health: evidence-based policy and practice +++

https://www.thelancet.com/journals/landig/article/PIIS2589-7500(25)00022-6/fulltext?dgcid=hubspot_update_feature_updatealerts_landig&utm_campaign=update-landig&utm_medium=email&_hsenc=p2ANqtz--y5ThKdmWsr522dF72AL_HTJbq6BQLghLVx067Hfs4CdoO6FtT06YV6ykdWhAz9M27CBObVS4GbPDk2E_EsY_jRG0omA&_hsmi=371433429&utm_content=371147702&utm_source=hs_email Jun 2025 Volume 7Number 6 https://www.thelancet.com/journals/landig/issue/vol7no6/PIIS2589-7500(25)X0006-6 Online video versus face-to-face preoperative consultation for major abdominal surgery (VIDEOGO): a multicentre, open-label, randomised, controlled, non-inferiority trial https://www.thelancet.com/journals/landig/article/PIIS2589-7500(25)00039-1/fulltext?dgcid=hubspot_update_feature_updatealerts_landig&utm_campaign=update-landig&utm_medium=email&_hsenc=p2ANqtz-8REhcdwvhQxPfkrt9Xrf7erAQmpeV3uo94nXGv_kA9pzHECWZXfjpIf34i25411v1ryQLKNb74de8_DALxXb58E4pqPA&_hsmi=371433429&utm_content=371147702&utm_source=hs_email

Evolving patterns of macrolide and fluoroquinolone resistance in Mycoplasma genitalium: an updated systematic review and meta-analysis ++

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(24)00315-X/fulltext?dgcid=hubspot_update_feature_updatealerts_lanmic&utm_campaign=update-lanmic&utm_medium=email&_hsenc=p2ANqtz-_65tQBVHjkPN9CbWHkEzFhGGT5ZjJfzReQ--Y61eZi0P_nrmEG-vR9sKVFImkqGAsGNCMTXEoSDjiC8stWQGRd-lFkAw&_hsmi=371442107&utm_content=371147167&utm_source=hs_email Population-level impact of mass drug administration against schistosomiasis with anthelmintic drugs targeting juvenile schistosomes: a modelling study https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(24)00333-1/fulltext?dgcid=hubspot_update_feature_updatealerts_lanmic&utm_campaign=update-lanmic&utm_medium=email&_hsenc=p2ANqtz-8ypR31Xo2ALEiGgxfIcgPLJ7siNMkOYHErxCU_joLFUUUPm2Hz4YqoTQ6p8djJ8UWCtosJJpVTbEGDVJbK1R-hdR5qUQ&_hsmi=371442107&utm_content=371147167&utm_source=hs_email

Performance of stool Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis among adults living with HIV: a multicentre, prospective diagnostic study +...

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00013-8/fulltext?dgcid=hubspot_update_feature_updatealerts_lanmic&utm_campaign=update-lanmic&utm_medium=email&_hsenc=p2ANqtz-9qmLr_-bEUj7hWlqi91ZBC13uNxXw4kmykZqoaB5ZslDbUq3gif308MpPJQ0_awqw8uWiR47PYDMs-Q2XbVW-NFZRE9w&_hsmi=371442107&utm_content=371147167&utm_source=hs_email Editorial Overcoming the dilemma of dengue diagnostics The Lancet Microbe https://www.thelancet.com/journals/lanmic/issue/vol6no7/PIIS2666-5247(25)X0007-0

Broken smiles: Why have some humans evolved to have crooked teeth Leah Worthington | National Geographic | July 21, 2025

https://geneticliteracyproject.org/2025/07/21/broken-smiles-why-have-some-humans-evolved-to-have-crooked-teeth/

Challenging RFK. Jr.’s misstatements on aluminum in vaccines: ‘No, the microscopic amounts play no role in autism’ Judy George | MedPage Today | July 21, 2025

https://geneticliteracyproject.org/2025/07/21/challenging-rfk-jr-s-misstatements-on-aluminum-in-vaccines-no-the-microscopic-amounts-play-no-role-in-autism/

Expanding appreciation for the patient journey

https://rarerevolutionmagazine.com/expanding-appreciation-for-the-patient-journey/

domingo, 20 de julio de 2025

Common medications impact gut microbiome and promote pathogen growth

https://www.news-medical.net/news/20250716/Common-medications-impact-gut-microbiome-and-promote-pathogen-growth.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=gastroenterology_newsletter_17_july_2025

Fast Facts: Inflammatory Bowel DiseaseFree By David S. Rampton; Fergus Shanahan

https://karger.com/books/book/6019/Fast-Facts-Inflammatory-Bowel-Disease?utm_source=email&utm_medium=external&utm_campaign=azo_newsletter_gastro The seventh edition of Fast Facts: Inflammatory Bowel Disease offers an updated overview of Crohn’s disease and ulcerative colitis, highlighting microbiome research and evolving treatment strategies. It covers the use of immunomodulators, biologics, and emerging therapies. Designed for non-specialist doctors, nurses, dietitians, and other healthcare professionals, this concise guide supports those involved in the care of patients with IBD.

Rapid Review: Endometrial Cancer Maurie Markman, MD

https://reference.medscape.com/viewarticle/endometrial-cancer-rapid-review-2025a1000ihn?_gl=1*5vevzu*_gcl_au*MTczMzE3MjAxOS4xNzQ2NzI0NDU0

Thimerosal in Vaccines: Myths vs. Medical Facts

https://www.news-medical.net/health/Thimerosal-in-Vaccines-Myths-vs-Medical-Facts.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=pharmacy_and_pharmacology_newsletter_18_july_2025

Retrospective analyses indicate Ozempic’s protective effects against stroke fatality

https://www.news-medical.net/news/20250718/Retrospective-analyses-indicate-Ozempice28099s-protective-effects-against-stroke-fatality.aspx

Study identifies SDR42E1's role in vitamin D pathway

https://www.news-medical.net/news/20250718/Study-identifies-SDR42E1s-role-in-vitamin-D-pathway.aspx

Study reveals complex patterns of burden and survival among people with digestive system cancers in China

https://www.news-medical.net/news/20250718/Study-reveals-complex-patterns-of-burden-and-survival-among-people-with-digestive-system-cancers-in-China.aspx

Diabetic nerve damage weakens bones by disrupting cell communication

https://www.news-medical.net/news/20250718/Diabetic-nerve-damage-weakens-bones-by-disrupting-cell-communication.aspx

Sound stress alone induces pain sensitivity and brain inflammation

https://www.news-medical.net/news/20250718/Sound-stress-alone-induces-pain-sensitivity-and-brain-inflammation.aspx

Innovative dynamic biomarker system unlocks new pathways in thyroid cancer management

https://www.news-medical.net/news/20250718/Innovative-dynamic-biomarker-system-unlocks-new-pathways-in-thyroid-cancer-management.aspx

Intratumoral microbiota reshape our understanding of cancer biology

https://www.news-medical.net/news/20250718/Intratumoral-microbiota-reshape-our-understanding-of-cancer-biology.aspx

Rethinking childhood obesity through gentle nutrition and emotional support

https://www.news-medical.net/news/20250718/Rethinking-childhood-obesity-through-gentle-nutrition-and-emotional-support.aspx

New insights into diagnosis and treatment of tibial tubercle avulsion fractures in young athletes

https://www.news-medical.net/news/20250718/New-insights-into-diagnosis-and-treatment-of-tibial-tubercle-avulsion-fractures-in-young-athletes.aspx

Agricultural dust exposure may pose significant risks to gut health

https://www.news-medical.net/news/20250718/Agricultural-dust-exposure-may-pose-significant-risks-to-gut-health.aspx

Women and Health: Uncovering Health-Care Disparities

https://www.thelancet.com/video-do/women-and-health?dgcid=hubspot_email_infocusalerts-obgyn_feature_infocuswomenhealth-video&utm_campaign=infocusalerts-obgyn&utm_medium=email&_hsenc=p2ANqtz-9pKLaLu1RU7n6oqjS489dTBkEJH8AQlpQj8tnVG1N9wKwwK1q6i4kOBbEZlPjz989YE7i2o-jS_nLHhXHr60ZAcB7neA&_hsmi=371955293&utm_content=371341608&utm_source=hs_email

Perspectives Accelerating women's health research and innovation Bola Grace

https://www.thelancet.com/journals/lanogw/onlinefirst?dgcid=hubspot_email_infocusalerts-obgyn_feature_lanogwlaunch&utm_campaign=infocusalerts-obgyn&utm_medium=email&_hsenc=p2ANqtz-9fvzIWMWZpz_HifYOus3QtC1tp1Ap_SKkuR5FGyIu55PDI1AuaBvbwmrXAcEs1thZHrb-SWxT3pxT4i1cdCqF-avDFhQ&_hsmi=371955293&utm_content=371341608&utm_source=hs_email

Use of Anti-Amyloid Therapies in the Setting of Mild Cognitive Impairment: A Patient-Clinician Vignette Authors: B. Joy Snider, MD, PhD

https://www.medscape.org/viewarticle/1002553_sidebar9?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_250719-1002553_ES_Lang_NEUR

Jul 18, 2025 This Week in Cardiology Podcast John M. Mandrola, MD July 18, 2025Jul 18, 2025

https://www.medscape.com/viewarticle/1002729?ecd=wnl_edit_tpal_etid7580536&uac=148436CN&impID=7580536

Educating, Empowering, and Engaging: A Focus on HER2-Activating Mutations in NSCLC Authors: Eric K. Singhi, MD; Thomas Newsom-Davis, FRCP, PhD; Soo-Ryum (Stewart) Yang, MD

https://www.medscape.org/viewarticle/1002375?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250719-OUS-HONC-1002375-cta

Designing the Optimal Care Plan for the Patient With Metastatic Castration-Resistant Prostate Cancer Authors: Bertrand Tombal, MD, PhD; Jonathan D. Tward, MD, PhD, FASTRO

https://www.medscape.org/viewarticle/1002397?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250720-OUS-HONC-1002397-cta