Nanostructured toxins for the selective destruction of drug-resistant human CXCR4style+ colorectal cancer stem cells

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Nanostructured toxins for the selective destruction of drug-resistant human CXCR4style+ colorectal cancer stem cells   A novel toxin-based nanoparticle drug specifically is designed to attack colorectal cancer stem cells with overexpression of the chemokine receptor CXCR4.

Rapid genomic profiling of colon cancers can improve therapy   Genomic mutation testing is critical to the therapeutic selection and management of patients with colorectal cancer.         Study reveals key biochemical processes that advance understanding of colorectal cancer   A new insight into cell signals that control cancer growth and migration could help in the search for effective anti-cancer drugs. A McGill-led study reveals key biochemical processes that advance our understanding of colorectal cancer, the third most common cancer among Canadians.

Chronic inflammation disrupts tissue structure of the colon, study finds   In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.       Vitamin D shows promise to alleviate side effects of chemotherapy   As many cancer patients will confirm, the chemotherapy prescribed to kill the disease is often more debilitating than the cancer itself, with a range of horrendous side effects.       Abnormal expression of Zeb2 protein in epithelial cells can induce colorectal cancer   A collaborative study by research groups from the VIB-UGent Center for Inflammation Research and Ghent University uncovered a new mechanism causing colorectal cancer.       Study: Hypertension medications can also reduce risk of colorectal cancer   Medications commonly prescribed to treat high blood pressure may also reduce patients' colorectal cancer risk, according to new research published today in Hypertension, an American Heart Association journal.

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