viernes, 14 de agosto de 2020

Monitoring spheroid response to cytotoxic challenge over time with fluorescent proteins

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 Monitoring spheroid response to cytotoxic challenge over time with fluorescent proteinsMonitoring spheroid response to cytotoxic challenge over time with fluorescent proteins
 
Within the cells of a spheroid, the expression of fluorescent proteins provide a readout of cell viability, where cytotoxic challenge will result in a loss of fluorescence signal, and spheroid growth results in an increase in fluorescence. Covering the Brightfield channel allows the objects of interest to be identified.
 
   Using Virtual-freezing to Combine Fluorescence Imaging and Flow CytometryUsing Virtual-freezing to Combine Fluorescence Imaging and Flow Cytometry
 
A team recently determined an imaging method based on optomechanics that overcomes the performance and utility of imaging flow cytometry (IFC).
 
   New Fluorescent Material Could Boost Optics TechnologyNew Fluorescent Material Could Boost Optics Technology
 
Maintaining fluorescence as dyes crystalize to form solids is a problem that has existed in materials for over 100 years. Now, a novel approach to tackling the issue and a revolutionary material could unlock a new age of optics technology.
 
   Chemists Develop the Brightest Known Fluorescent Materials in ExistenceChemists Develop the Brightest Known Fluorescent Materials in Existence
 
By formulating positively charged fluorescent dyes into a new class of materials called small-molecule ionic isolation lattices, a compound's brilliant glow can be seamlessly transferred to a solid, crystalline state, researchers report August 6 in the journal Chem.
 
   Fluorescent molecules in urine can help monitor malignant melanomaFluorescent molecules in urine can help monitor malignant melanoma
 
What if you could simply provide a urine sample rather than undergo a painful surgical procedure to find out if your cancer was responding to treatment? It may seem too good to be true, but researchers at Pavol Jozef šafárik University in Košice, Slovakia, have identified fluorescent molecules in urine that may allow patients with malignant melanoma to do just that.
 
 
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