CIENCIASMEDICASNEWS: How to Ensure Quantitative Accuracy in PET

jueves, 16 de abril de 2020

How to Ensure Quantitative Accuracy in PET

	Drug Discovery and Production
	The latest drug discovery news from News Medical

How to Ensure Quantitative Accuracy in PET

Image quality is only one aspect of functional imaging with PET and SPECT. The ability to reproducibly extract quantitative information from our images is critical to research.

Discover in this webinar:

The importance of QC for scanners: calibration, reconstruction, and corrections.
PMOD’s software package for multimodality image analysis: data QC after loading or import, important aspects of segmentation and their effect on SUV, time-activity curves and kinetic modeling.
Important PET/SPECT image formats and their metadata.

Overcoming PROTAC Evaporation Bottlenecks

An evolving class of therapeutics has the potential to allow the design of new drugs targeting “undruggable” proteins which make up to 85% of the proteome. They are called PROteolysis TArgeting Chimeras (PROTACs). Yet, synthesis of PROTACs needs several evaporation steps, leading to bottlenecks in their workflow and a reduction in the speed of the drug development process. Many have researched PROTACs and the benefits they can offer to the drug discovery field. Further discussions have investigated the issues with their synthesis, and how this can be overcome.

Learn More

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