Smoking Cessation: Public Health & Genetic Insights

Genomics|Update|Current

Smoking Cessation: Public Health & Genetic Insights

Increases in smoking cessation interventions after a feedback and improvement initiative using electronic health records — 19 community health centers, New York City, October 2010–March 2012 
Sheryl L. Silfen, et al. MMWR 2014;63:921-4

The genetic architecture of smoking and smoking cessation 
dbGaP Study Accession: phs000404.v1.p1 This study includes samples from two projects:

Genomics and personalized medicine: CHRNA5-CHRNA3-CHRNB4 and smoking cessation treatment. 
Chen LS, Bierut LJ. J Food Drug Anal. 2013 Dec;21(4):S87-S90.

Interplay of genetic risk (CHRNA5) and environmental risk (partner smoking) on cigarette smoking reduction. 
Chen LS, et al. Drug Alcohol Depend. 2014 Oct 1;143:36-43.

Impact of genetic notification on smoking cessation: Systematic review and pooled-analysis. 
Sylviane de Viron et al. PLOS One, 2012

CHRNA5 variant predicts smoking cessation in patients with acute myocardial infarction. 
Chen LS, et al. Nicotine Tob Res. 2014 Sep;16(9):1224-31

Environmental and genomic factors influencing smoking cessation: A systematic review of reviews and a proposed working model
de Viron S et al. Public Health Genomics (2013)

CDC blog post (2012): Smokescreen: What's genomics got to do with smoking?

Find out about genetic conditions and tests associated with smoking from the NIH Genetic Testing Registry

Did you know? There are thousands of genes reported in relation to smoking addiction and adverse health outcomes, including > 100 genomewide association studies. Check out the HuGE Navigator