Human Infections with Borrelia miyamotoi, Japan - Volume 20, Number 8—August 2014 - Emerging Infectious Disease journal - CDC
Volume 20, Number 8—August 2014
Human Infections with Borrelia miyamotoi, Japan
Borrelia miyamotoi, which is genetically grouped with relapsing fever borreliae, was recently identified as a human pathogen in Russia (1), the United States (2–4), and Europe (5). Ticks of the Ixodes persulcatus species complex are transmission vectors. Pathogenic borreliae were discovered in I. persulcatus ticks in Japan (6).
In areas of Japan to which Lyme disease is endemic, wild rodents have been found to be infected with B. miyamotoi (7), although no human infections have been confirmed. B. miyamotoi isolates from Japan are potential human pathogens because they form a monophyletic lineage with isolates from patients in Russia (1). We conducted a retrospective investigation to identify occult cases of human infections with B. miyamotoi in Japan.