Family history is 'a bigger risk factor than lifestyle' for some cancers - Medical News Today
Family history is 'a bigger risk factor than lifestyle' for some cancers
If a person's biological parent had cancer, there was an 80-100% higher chance of them developing the same disease than if their natural parents were free of the cancer.
The genetic factors behind these three major cancers are well established, but this large survey of data published in the European Journal of Cancer has looked a unique group of people in a bid to disentangle familial risk from environmental factors.
By looking at adoptees, the researchers were able to see how being raised in an environment that was independent of hereditary genetics - being brought up by adoptive parents - revealed the true extent of the biological influence exerted by the genes of their real parents.
In effect, the study separated out the cancer effects of family history versus those of the environment.
If a person's biological parent had cancer, there was an 80-100% higher chance of them developing the same disease than if their natural parents were free of the cancer.
Yet the history of adoptive parents had no influence on the risk of developing cancer. If an adoptive parent had cancer, there was no increased effect on the adoptee.
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