Genomics|Update|Current: CANCER

Genomics|Update|Current

Cancer

Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations
Hongmei Nan, et al. JNCI, Dec 7

BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface 
Lee AJ, et al. Br J Cancer 2013 Dec

Cancer genetic counselor information needs for risk communication: A qualitative evaluation of interview transcripts 
Overby CL, et al. J Pers Med 2013;3(3)

Consortium launches genotyping effort 
Cancer Discov 2013 Dec;3(12):1321-2

Network formed to discover new cancer susceptibility variants, NCI Cancer Epidemiology Matters News, Dec 2013

Do BRCA1 and BRCA2 mutation carriers have earlier natural menopause than their noncarrier relatives? Results from the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer.
Collins IM, et al. J Clin Oncol. 2013 Nov 1;31(31):3920-5.

Identifying potential cancer driver genes by genomic data integration
Yong Chen et al. Nature, 2013 Dec 18 

Outcome of unexpected adnexal neoplasia discovered during risk reduction salpingo-oophorectomy in women with germ-line BRCA1 or BRCA2 mutations 
Conner JR, et al. Gynecol Oncol 2013 Dec

Optimizing recruitment to a prostate cancer surveillance program among male BRCA1 mutation carriers: invitation by mail or by telephone 
Galor A, et al. Hered Cancer Clin Pract 2013 Dec;11(1):17

When will genomics cure cancer? A conversation with the biogeneticist Eric S. Lander about how genetic advances are transforming medical treatment, by James Fallows, the Atlantic, Dec 22

In BRCA, tamoxifen may reduce contralateral breast cancer risk, Clinical Oncology, Dec 2013

Angelina didn't help educate people about breast cancer risk, by Maanvi Singh, National Public Radio Dec 20

Communication and technology in genetic counseling for familial cancer.
Lynch HT,  et al Clin Genet. 2013 Nov 8

Somatic mutations in MLH1 and MSH2 are a frequent cause of mismatch-repair deficiency in Lynch syndrome-like tumors.
Gastroenterology. 2013 Dec 9

Risk management options elected by women after testing positive for a BRCA mutation 
Garcia C, et al. Gynecol Oncol 2013 Dec