Telltale hearts. Each year, tens of thousands of young people worldwide die suddenly after their hearts stop beating for no apparent reason. Genetic testing for inherited heart rhythm disorders AKA 'molecular autopsies' are rarely performed.
Jeanne Erdmann. Nature Medicine, Nov 8
Extensive variation in chromatin states across humans
Maya Kasowski et al, Science, Nov 8
Genetics driving epigenetics.
Terrence S. Furey et al. Science, Nov 8
Genome-wide consequences of deleting any single gene
Teng X, et al. Molecular Cell, 2013 Nov 7
The vicious cycle of under-valued cancer biomarkers. Could sweeping changes bring more tests into clinical practice?
Genna Rollins, American Association for Clinical Chemistry, Nov 2013
Blog post: One person, many genomes, by Tom Insel, NIMH Director, Nov 2013
First director named for NHGRI's new Division of Genomics and Society, NIH News, Nov 14
NextCODE Health Mines deCODE's data, and more, to catalyze clinical diagnosis, by Ricki Lewis, DNA Science Blog, Nov 14
When causal disease alleles don't cause disease (or is that the norm?) By Anne Buchanan, The Mermaid's Tale, Nov 13
Can genomics blow up the clinical trial? Technology Review, Nov 12
How much bioinformatics does the new biologist need? By Ayanna Monteverdi, mendelspod, Nov 11
Weak statistical standards implicated in scientific irreproducibility- One-quarter of studies that meet commonly used statistical cutoff may be false. Erika Check Hayden, Nature News , Nov 11
Documentary: Exosomes – the next small thing, by Alexey Bersenev, Nov 9
Receptive to replication: Do replication studies belong in top-tier journals? Nature Biotechnology, Nov 8
Heterogeneity in cancer genomics, Ewan’s Blog, Nov 7
Practicing precision medicine in cancer using genomics - Louis Staudt, Video, Nov 7