The Office of Public Health Genomics (OPHG) provides updated and credible information on how genomic
information and family health history can improve health and influence policy and practice. We highlight
news and information on the use of genomic tests and other applications, including family health history,
in clinical and public health practice and programs, along with relevant data, policy, and legislation. We hope the update is informative to practitioners, policy makers, consumers, and researchers. Please send
your comments to: email@example.com
May is Arthritis Awareness Month
- CDC information: It is the perfect time to pump up your physical activity
- CDC arthritis public health information: Arthritis is the most common cause of disability in the United States
- CDC information: Arthritis risk factors including specific genetic factors
- There are 100+ forms of arthritis. Osteoarthritis and rheumatoid arthritis are most common, Mayo Clinic
- Did you know that 1360 genes have been reported in relation to the risk of arthritis including 124 genomewide association studies. To find out more, visit the HuGE Navigator.
Certain factors have been shown to be associated with a greater risk of arthritis. Some of these risk factors are modifiable while others are not.
Non-modifiable risk factors
- Age: The risk of developing most types of arthritis increases with age.
- Gender: Most types ofarthritis are more common in women; 60% of all people with arthritis are women. Gout is more common in men.
- Genetic: Specific genes are associated with a higher risk of certain types of arthritis, such as rheumatoid arthritis (RA), systemic lupus erythematous (SLE), and ankylosing spondylitis.
Modifiable risk factors
- Overweight and Obesity: Excess weight can contribute to both the onset and progression of knee osteoarthritis.
- Joint Injuries: Damage to a joint can contribute to the development of osteoarthritis in that joint.
- Infection: Many microbial agents can infect joints and potentially cause the development of various forms of arthritis.
- Occupation: Certain occupations involving repetitive knee bending and squatting are associated with osteoarthritis of the knee.