Ahead of Print - Novel SARS-like Betacoronaviruses in Bats, China, 2011 - Vol. 19 No. 6 - June 2013 - Emerging Infectious Disease journal - CDC
Volume 19, Number 6—June 2013
Novel SARS-like Betacoronaviruses in Bats, China, 2011
The 2003 outbreak of severe acute respiratory syndrome (SARS) was caused by a novel betacoronavirus and rapidly spread globally, causing ≈8,000 cases and nearly 900 deaths (1,2). In June 2012, a novel betacoronavirus (called human coronavirus EMC [HCoV-EMC]) also was isolated from the sputum of a patient from Saudi Arabia who died of pneumonia and renal failure (3). Similar viruses were detected in 2 additional patients who had severe pneumonia in Qatar in September 2012 and in Saudi Arabia in November 2012 (4,5). The clinical picture was remarkably similar to that of SARS and illustrates the epidemic potential of a novel coronavirus (CoV) to threaten global health. SARS-CoVs and HCoV-EMC were suspected of spreading from bats to humans because these CoVs were most closely related to bat CoVs (1,4). To clarify the evolutionary relationships among betavoronaviruses that infect bats, we analyzed samples collected during 2010–2011 from 14 insectivorous bat species common in 8 provinces in China.