National Guideline Clearinghouse | The 2012 hormone therapy position statement of The North American Menopause Society.

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National Guideline Clearinghouse | The 2012 hormone therapy position statement of The North American Menopause Society.

Guideline Title

The 2012 hormone therapy position statement of The North American Menopause Society.

 

 

Bibliographic Source(s)

The North American Menopause Society. The 2012 hormone therapy position statement of the North American Menopause Society. Menopause 2012 Mar;19(3):257-71. [173 references] PubMed

 

 

Guideline Status

This is the current release of the guideline.
This guideline updates a previous version: North American Menopause Society. Estrogen and progestogen use in postmenopausal women: 2010 position statement of The North American Menopause Society. Menopause 2010 Mar;17(2):242-55.

Menopause. 2012 Mar;19(3):257-71.

The 2012 hormone therapy position statement of: The North American Menopause Society.

North American Menopause Society.

Collaborators (36)

Gass ML, Heights M, Manson JE, Cosman F, Hayes H, Grodstein F, Lab C, Jordan V, Karas RH, Kaunitz AM, Maki PM, Schmidt PJ, Shifren JL, Stuenkel CA, Utian WH, Wisch KJ, Bilancini AM, Clarkson TB, Gass ML, Heights M, Goldstein SR, Kagan R, Kaunitz AM, Maki PM, Manson JE, Pace DT, Schiff I, Meigs JV, Obstetrics V, Schnatz PF, Shapiro M, Shifren JL, Obstetrics V, Sievert LL, Utian WH, Warren MP.

Abstract

OBJECTIVE:

This position statement aimed to update the evidence-based position statement published by The North American Menopause Society (NAMS) in 2010 regarding recommendations for hormone therapy (HT) for postmenopausal women. This updated position statement further distinguishes the emerging differences in the therapeutic benefit-risk ratio between estrogen therapy (ET) and combined estrogen-progestogen therapy (EPT) at various ages and time intervals since menopause onset.

METHODS:

An Advisory Panel of expert clinicians and researchers in the field of women's health was enlisted to review the 2010 NAMS position statement, evaluate new evidence, and reach consensus on recommendations. The Panel's recommendations were reviewed and approved by the NAMS Board of Trustees as an official NAMS position statement.

RESULTS:

Current evidence supports the use of HT for perimenopausal and postmenopausal women when the balance of potential benefits and risks is favorable for the individual woman. This position statement reviews the effects of ET and EPT on many aspects of women's health and recognizes the greater safety profile associated with ET.

CONCLUSIONS:

Recent data support the initiation of HT around the time of menopause to treat menopause-related symptoms and to prevent osteoporosis in women at high risk of fracture. The more favorable benefit-risk ratio for ET allows more flexibility in extending the duration of use compared with EPT, where the earlier appearance of increased breast cancer risk precludes a recommendation for use beyond 3 to 5 years.

PMID:

22367731

[PubMed - in process]

The 2012 hormone therapy position statement of: Th... [Menopause. 2012] - PubMed - NCBI