lunes, 15 de diciembre de 2025

Academia Drug Development and Pharmacotherapy: a new scientific translational journal focused on personalized therapy Federico Pea* [1,2]

Academia.edu is launching a new scientific journal in the field of drug development and pharmacotherapy. This will be a translational journal focused on all the different aspects which, from bench to bedside, may enable maximizing the likelihood of providing more effective and safe pharmacotherapy in the era of precision medicine. Modern pharmacotherapy is increasingly based on well-defined molecular targets, and this may clearly improve effectiveness, especially in some fields such as oncology. However, there is an urgent need to personalize therapy to each individual patient, escaping from the false contention that “one size may fit all” and moving toward tailored therapies based on predictive models. This has been well-defined in the last twenty years or so, especially in the field of antibiotic therapy, in which both underlying diseases and pathophysiology have been shown to deeply alter the pharmacokinetic–pharmacodynamic behavior of drugs with the consequent need of individualized dosing regimens. Indeed, the same is also expected to occur in other therapeutic areas, and just to mention one among many, recent studies suggest that a paradigm shift to personalized dosing regimens might be applied even to the major topic of therapeutic monoclonal antibodies. https://www.academia.edu/academia-drug-development-and-pharmacotherapy/1/1/10.20935/AcadDrug7906

What are the treatment options for Rheumatoid Arthritis (Medscape AI) +... +++++

https://www.medscape.com/ai-search?query=What%20are%20the%20treatment%20options%20for%20Rheumatoid%20Arthritis&&ecd=mkm_ret_251215_mscpmrk-OUS_InFocus_etid7949649&uac=148436CN&impID=7949649 Could SGLT2 Inhibitors Reduce Rheumatoid Arthritis Flares? https://www.medscape.com/viewarticle/could-sglt2-inhibitors-reduce-rheumatoid-arthritis-flares-2025a1000xvs?ecd=mkm_ret_251215_mscpmrk-OUS_InFocus_etid7949649&uac=148436CN&impID=7949649 Fiber, Bacteria Likely Influence Methotrexate Response in RA https://www.medscape.com/viewarticle/fiber-gut-bacteria-likely-influence-methotrexate-response-2025a1000xyt?ecd=mkm_ret_251215_mscpmrk-OUS_InFocus_etid7949649&uac=148436CN Do Patients With RA on ICIs Have a Higher Mortality Risk? https://www.medscape.com/viewarticle/do-patients-ra-immune-checkpoint-inhibitors-have-higher-2025a1000x5y?ecd=mkm_ret_251215_mscpmrk-OUS_InFocus_etid7949649&uac=148436CN&impID=7949649 Risk Score Validated to Predict Lung Disease in RA https://www.medscape.com/viewarticle/risk-score-validated-predict-lung-disease-rheumatoid-2025a1000x62?ecd=mkm_ret_251215_mscpmrk-OUS_InFocus_etid7949649&uac=148436CN&impID=7949649 Sleep Disorders Common in RA, Many Tied to Disease Activity https://www.medscape.com/viewarticle/sleep-disorders-common-ra-many-tied-disease-activity-2025a1000vue?ecd=mkm_ret_251215_mscpmrk-OUS_InFocus_etid7949649&uac=148436CN&impID=7949649

Addressing Challenges for Patients With HR+/HER2- EBC: Managing AEs and Optimizing Adherence Authors: Sarah Donahue, MPH, NP, AOCNP; Erika Hamilton, MD; Nadia Harbeck, MD, PhD

https://www.medscape.org/viewarticle/1002936?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251215-OUS-HONC-1002936-cta

AI helps radiologists find breast cancers earlier and faster Rather than replacing radiologists, AI is working alongside them to catch cancers earlier and improve screening efficiency.

https://www.drugdiscoverynews.com/ai-helps-radiologists-find-breast-cancers-earlier-and-faster-16830

Why we’re going back to the moon By Bioethics Observatory Published On: November 3rd, 2025

https://bioethicsobservatory.org/2025/11/why-were-going-back-to-the-moon/48159/?utm_source=mailpoet&utm_medium=email&utm_source_platform=mailpoet

Stem cells and organoids: the revolution transforming biomedicine that demands bioethical reflection By Bioethics Observatory Published On: November 28th, 2025

https://bioethicsobservatory.org/2025/11/stem-cells-and-organoids-the-revolution-transforming-biomedicine-that-demands-bioethical-reflection/48221/?utm_source=mailpoet&utm_medium=email&utm_source_platform=mailpoet

Social networks, digital screen exposure, and neurodevelopmental disorders By Bioethics Observatory Published On: December 3rd, 2025

https://bioethicsobservatory.org/2025/12/social-networks-digital-screen-exposure-and-neurodevelopmental-disorders/48247/?utm_source=mailpoet&utm_medium=email&utm_source_platform=mailpoet