New clinical trial offers hope for patients with advanced “dry” age-related macular degeneration

https://www.news-medical.net/news/20251217/New-clinical-trial-offers-hope-for-patients-with-advanced-e2809cdrye2809d-age-related-macular-degeneration.aspx

Sitting harms blood vessel function, but cocoa flavanols can stop it

https://www.news-medical.net/news/20251217/Sitting-harms-blood-vessel-function-but-cocoa-flavanols-can-stop-it.aspx A simple cocoa-based intervention taken just before long periods of sitting can help preserve blood vessel function in both the arms and the legs. This highlights a practical nutritional strategy to counter the hidden cardiovascular risks of modern sedentary life.

Editorial e927 Acute myeloid leukaemia at the extremes The Lancet Haematology ++ +...

Fixed-duration ibrutinib–venetoclax with MRD-guided ibrutinib–obinutuzumab intensification in first-line chronic lymphocytic leukaemia (HOVON 158/NEXT STEP): primary analysis of a multicentre, open-label, phase 2 trial https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(25)00288-1/abstract?utm_campaign=update-lanhae&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanhae&_hsenc=p2ANqtz-8KGpoy87VI4ht9FYkINihi8PvuSRwkHWCVB3G75Ms9LnxUXLu7fG0wtuA1WLiBXtkOnWj4rImaLvzaCaNVLgE7NWsZ8Q&_hsmi=394395134&utm_content=393827040&utm_source=hs_email Motivators and barriers affecting decisions to participate in sickle cell disease clinical trials in the global Learning and Insights into Sickle Cell Trial Experiences (LISTEN) Survey: global and regional findings https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(25)00295-9/abstract?utm_campaign=update-lanhae&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanhae&_hsenc=p2ANqtz--uO0YWGE69YvRfurJq8h-auWMBUoABX5SKuwQOWl8klgI_CeP54dTefS36F5f1aY3yQkpMkagDkis00W9HgNjRSDAvkA&_hsmi=394395134&utm_content=393827040&utm_source=hs_email Editorial e927 Acute myeloid leukaemia at the extremes The Lancet Haematology https://www.thelancet.com/journals/lanhae/issue/vol12no12/PIIS2352-3026(25)X0012-0

Advancing Treatment for HER2-Positive Advanced Breast Cancer: Expert Analysis of the Latest Developments Authors: Judy King, MRCP, PhD; Peter Fasching, MD

https://www.medscape.org/viewarticle/1002765?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251215-OUS-HONC-1002765-cta

Navigating the Storm of Heavily Pretreated Multiple Myeloma: Calming the Waters With Bispecific Antibodies Authors: Hermann C. Einsele, MD, PhD; Xavier Leleu, MD, PhD; Naresh Bumma, MD

https://www.medscape.org/viewarticle/1002692?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251216-OUS-HONC-1002692-cta

Patients’ Insights Illuminated: A Rapid-Fire Dive Into CLL and MCL Authors: Lorna Warwick; Toby A. Eyre, MBChB, DipMedEd, MRCP, FRCPath, MD; Nicole Lamanna, MD; David Ball; Vivienne Ball

https://www.medscape.org/viewarticle/1002737?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251216-OUS-HONC-1002737-cta

Latest Advances in Tumor-Agnostic Strategies for NTRK Fusion-Positive Cancer: Translating Science Into Clinical Practice Authors: Rahul Gosain, MD, MBA; Rohit Gosain, MD; David S. Hong, MD; Theodore W. Laetsch, MD; Jarushka Naidoo, MB, BCH, MHS

https://www.medscape.org/viewarticle/1002679?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251216-OUS-HONC-1002679-cta