Challenge of Evidence in Individualized Medicine: Abstract and Introduction

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Challenge of Evidence in Individualized Medicine: Abstract and Introduction

From Personalized Medicine

Challenge of Evidence in Individualized Medicine

Kathleen Kraft; Wolfgang Hoffmann

Authors and Disclosures

Posted: 01/17/2012; Personalized Medicine. 2012;9(1):65-71. © 2012 Future Medicine Ltd.

 

• Abstract and Introduction
• Evidence-based Medicine or Individualized Therapy?
• Why Are Guidelines Hardly Applied in Practice?
• Stratification as a Link Between EBM & Individualized Medicine?
• Individualized Medicine in Guidelines?
• Conclusion & Future Perspective

• References
• Sidebar

Abstract and Introduction

Abstract

Tension between standardization and individualization has always been a characteristic of medical activity. However, whether it is better that interventions should be based on guideline recommendations on the basis of large multicenter trials, or on a genetic biomarker in individualized medicine, can be the subject of debate. With the aid of stratification, evidence-based medicine and individualized medicine could be linked. Networks of large research projects, involving clinical, biomedical, molecular and other expertises are necessary for evidence-based evaluation, standardization, and clinical validation of new methods and algorithms.

 

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