Selective Serotonin Reuptake Inhibitor Toxicity

https://emedicine.medscape.com/article/821737-overview?ecd=WNL_conf_psych_APA-NON-SPON_250607_MSCPEDIT_etid7477289&uac=148436CN&impID=7477289 Selective serotonin reuptake inhibitors (SSRIs), widely prescribed medications for the treatment of depression, obsessive-compulsive disorder, bulimia, anorexia nervosa, panic disorder, anxiety, and social phobia, have a high therapeutic-to-toxicity ratio. However, although they are associated with less toxicity than tricyclic antidepressants (TCAs), they are often involved in co-ingestions that can precipitate the potentially lethal serotonin syndrome (SS). (See Etiology.)