viernes, 28 de febrero de 2025

Impact of lockdown on stress eating

https://www.news-medical.net/news/20250228/Impact-of-lockdown-on-stress-eating.aspx

The Science Behind Long COVID Brain Fog

https://www.news-medical.net/health/The-Science-Behind-Long-COVID-Brain-Fog.aspx

Health organizations collaborate to address idiopathic pulmonary fibrosis on Rare Disease Day 2025

https://www.news-medical.net/news/20250228/Health-organizations-collaborate-to-address-idiopathic-pulmonary-fibrosis-on-Rare-Disease-Day-2025.aspx

How social media spreads diet misinformation—and what experts say must change

https://www.news-medical.net/news/20250227/How-social-media-spreads-diet-misinformatione28094and-what-experts-say-must-change.aspx

Management of oligoprogressive and oligopersistent disease in advanced NSCLC.

https://read.qxmd.com/read/39907576/management-of-oligoprogressive-and-oligopersistent-disease-in-advanced-nsclc?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

Novel treatment strategy targeting interleukin-6 induced by cancer associated fibroblasts for peritoneal metastasis of gastric cancer.

https://read.qxmd.com/read/39863722/novel-treatment-strategy-targeting-interleukin-6-induced-by-cancer-associated-fibroblasts-for-peritoneal-metastasis-of-gastric-cancer?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

Unraveling the causal association between inflammatory bowel diseases and uveitis through mendelian randomization analysis.

https://read.qxmd.com/read/39956872/unraveling-the-causal-association-between-inflammatory-bowel-diseases-and-uveitis-through-mendelian-randomization-analysis?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

How to manage sodium-glucose cotransporter-2 inhibitors in the critically ill patient?

https://read.qxmd.com/read/39621048/how-to-manage-sodium-glucose-cotransporter-2-inhibitors-in-the-critically-ill-patient?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

Nelarabine in T-cell acute lymphoblastic leukemia: intracellular metabolism and molecular mode-of-action.

https://read.qxmd.com/read/39962329/nelarabine-in-t-cell-acute-lymphoblastic-leukemia-intracellular-metabolism-and-molecular-mode-of-action?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

Clinical implications of epithelial-to-mesenchymal transition in cancers which potentially spread to peritoneum.

https://read.qxmd.com/read/39775727/clinical-implications-of-epithelial-to-mesenchymal-transition-in-cancers-which-potentially-spread-to-peritoneum?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

Physicochemical and structural insights into lyophilized mRNA-LNP from lyoprotectant and buffer screenings.

https://read.qxmd.com/read/39059500/physicochemical-and-structural-insights-into-lyophilized-mrna-lnp-from-lyoprotectant-and-buffer-screenings?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

Tafasitamab in refractory diffuse large B-cell lymphoma with neurolymphomatosis.

https://read.qxmd.com/read/39934427/tafasitamab-in-refractory-diffuse-large-b-cell-lymphoma-with-neurolymphomatosis?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

The origins of the definition of complete remission in acute myeloid leukemia.

https://read.qxmd.com/read/39895332/the-origins-of-the-definition-of-complete-remission-in-acute-myeloid-leukemia?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

Reduced-volume radiotherapy versus conventional-volume radiotherapy after induction chemotherapy in nasopharyngeal carcinoma: An open-label, noninferiority, multicenter, randomized phase 3 trial.

https://read.qxmd.com/read/39970442/reduced-volume-radiotherapy-versus-conventional-volume-radiotherapy-after-induction-chemotherapy-in-nasopharyngeal-carcinoma-an-open-label-noninferiority-multicenter-randomized-phase-3-trial?uac=148436CN&ecd=wnl_readmost_250228&sso=true&redirected=slug

Most Read Papers - Cancer Science & Oncogenesis

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_250228

NCI Clinical Trials Update for February 2025

https://content.govdelivery.com/accounts/USNIHNCI/bulletins/3cff970?reqfrom=share

Why do we remember some dreams and not others? Lauren Fuge | Cosmos | February 28, 2025

https://geneticliteracyproject.org/2025/02/28/why-do-we-remember-some-dreams-and-not-others/?mc_cid=d7eebbd37b&mc_eid=b73600b7ac

Has PSA Screening Guidance Upped Prostate Cancer Incidence and Mortality? Will Pass February 10, 2025 +++ +++

TRENDING PSA Screening Worsening Outcomes? Has PSA Screening Guidance Upped Prostate Cancer Incidence and Mortality? Will Pass February 10, 2025 https://www.medscape.com/viewarticle/have-anti-psa-screening-guidelines-upped-prostate-cancer-2025a100039w?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665 Cancer Risk & Brews: New Data Coffee and Tea Linked to Reduced Cancer Risk, but the Cup Is Murky Jennie Smith February 10, 2025 https://www.medscape.com/viewarticle/coffee-and-tea-linked-reduced-cancer-risk-cup-murky-2025a10003ca?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665 Is It Ever Safe to Use the Word ‘Cure’? ‘Cure’ in Cancer: Should Oncologists Use the Word? Kate Johnson February 04, 2025 https://www.medscape.com/viewarticle/cure-cancer-should-oncologists-use-word-2025a10002q4?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665 DIAGNOSTIC INSIGHTS Why Identifying Pancreatic Cancer Remains Elusive Identifying Pancreatic Cancer Remains Elusive: Here’s Why Carolyn Crist February 18, 2025 https://www.medscape.com/viewarticle/identifying-pancreatic-cancer-remains-elusive-heres-why-2025a100045t?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665 New Test Promising in Bladder Cancer Detection Urine-Based Test Shows Promise in Detecting Bladder Cancer Edited by Gargi Mukherjee February 07, 2025 https://www.medscape.com/viewarticle/urine-based-test-shows-promise-detecting-bladder-cancer-2025a100034k?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665 Diagnostic Considerations in Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia (CLL) Differential Diagnoses https://emedicine.medscape.com/article/199313-differential?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665

THERAPEUTIC ADVANCES ++++

THERAPEUTIC ADVANCES OTC Med Cuts CRC Recurrence by Half Low-Dose Aspirin Cuts CRC Recurrence Megan Brooks January 28, 2025 https://www.medscape.com/viewarticle/low-dose-aspirin-cuts-crc-recurrence-2025a100022s?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665 The Diet That May Slow Prostate Cancer Diet Changes Show Promise in Early Prostate Cancer Megan Brooks February 20, 2025 https://www.medscape.com/viewarticle/diet-changes-show-promise-early-prostate-cancer-2025a10004gr?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665 New Ovarian Cancer Guidelines: Treatment Shift ASCO Updates Treatment Guidance for Newly Diagnosed, Advanced Ovarian Cancer Christos Evangelou, MSc, PhD February 24, 2025 https://www.medscape.com/viewarticle/asco-updates-treatment-guidance-newly-diagnosed-advanced-2025a10004ox?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665 Drug Duo Enhances Myeloma Outcomes Drug Duo Enhances Myeloma Outcomes Edited by Susan Ruel, PhD January 26, 2025 https://www.medscape.com/viewarticle/drug-duo-enhances-myeloma-outcomes-2025a10001w2?ecd=mkm_ret_250228_mscpmrk_onc_top-content_etid7259665&uac=148436CN&impID=7259665

jueves, 27 de febrero de 2025

New 4D Brain Map reveals potential early warning signs of multiple sclerosis NIH study reveals key players underlying disease onset and repair.

https://www.nih.gov/news-events/news-releases/new-4d-brain-map-reveals-potential-early-warning-signs-multiple-sclerosis

Who Should Take Weight Loss Injections, and Who Shouldn’t?

https://www.news-medical.net/health/Who-Should-Take-Weight-Loss-Injections-and-Who-Shouldne28099t.aspx

Is there an evolutionary explanation for human’s love of music? February 26, 2025

https://geneticliteracyproject.org/2025/02/26/is-there-an-evolutionary-explanation-for-humans-love-of-music-2/?mc_cid=aeb4a2a9dd&mc_eid=b73600b7ac

In the fight against opioid addiction, a new fentanyl vaccine could be an effective weapon Dallas Morning News Editorial | Dallas Morning News | February 26, 2025

https://geneticliteracyproject.org/2025/02/26/in-the-fight-against-opioid-addiction-a-new-fentanyl-vaccine-could-be-an-effective-weapon/?mc_cid=aeb4a2a9dd&mc_eid=b73600b7ac

The anti-vaccination movement claims its first measles victim since 2015—A Texas school child whose parents refused to get vaccinated Steve Schering | American Academy of Pediatrics | February 27, 2025

https://geneticliteracyproject.org/2025/02/27/the-anti-vaccination-movement-claims-its-first-measles-victim-since-2015-a-texas-school-child-whose-parents-refused-to-get-vaccinated/?mc_cid=aeb4a2a9dd&mc_eid=b73600b7ac

Can eating too much protein hurt us? Hillary Kaufman | February 27, 2025

https://geneticliteracyproject.org/2025/02/27/can-eating-too-much-protein-hurt-us/?mc_cid=aeb4a2a9dd&mc_eid=b73600b7ac

Advancing Cancer Care and Research Together

The liver–brain axis in metabolic dysfunction-associated steatotic liver disease

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00320-0/abstract?utm_campaign=update-langas&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_langas&_hsenc=p2ANqtz-_ArDzqd-qTf6B_dYgY7NwswGVqzzOeBLHS12uiTtAAgHbCUz26Sb3_VFkxO4WRPxfEl8nmppYS0jjX6SSSH9f8wUE_hw&_hsmi=348848710&utm_content=348779016&utm_source=hs_email

Management of hepatocellular carcinoma Published: February 21, 2025

https://www.thelancet.com/series/management-of-hepatocellular-carcinoma?dgcid=hubspot_update_feature_langashcc25&utm_campaign=update-langas&utm_medium=email&_hsenc=p2ANqtz-_oK4-8KyYNr14OWoq_waRYshCjxUc_Oa2LW2BR84qNUXxZ4MW80SgrOKb_40wwYw0iJ1t6UtMx5Injq0GKgVeYaPU0aQ&_hsmi=348848710&utm_content=348779016&utm_source=hs_email

Alcohol and cancer risk: bridging the awareness gap The Lancet Gastroenterology & Hepatology

https://www.thelancet.com/journals/langas/issue/vol10no3/PIIS2468-1253(25)X0002-9

Antibiotic treatment versus appendicectomy for acute appendicitis in adults: an individual patient data meta-analysis

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00349-2/abstract?utm_campaign=update-langas&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_langas&_hsenc=p2ANqtz-_C3ZbQZ6R-epsq7crvyLSfMDuv4q_xSKK7R_JsELSfkdX52j3PY1XAxbxih5RFUXx7_HQ532FV78TjkGPP2Q7tGcNVsw&_hsmi=348848710&utm_content=348779016&utm_source=hs_email

Aspirin after completion of standard adjuvant therapy for colorectal cancer (ASCOLT): an international, multicentre, phase 3, randomised, double-blind, placebo-controlled trial

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00387-X/abstract?utm_campaign=update-langas&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_langas&_hsenc=p2ANqtz-_Zv9QsiVqaRjdXRNl3pqfSayY8K4-oslRY0XX8KybAOh2YcYG7lMpp2iC3RrUw3FXYoYeFPa-uAuhL8IJM8m8kJmx_SA&_hsmi=348848710&utm_content=348779016&utm_source=hs_email

Perioperative lung expansion and pulmonary outcomes after abdominal surgery

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00053-0/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_sccm25&_hsenc=p2ANqtz-_0E6s7KUUYterxDejJLtRQ3HF4MBvO4chtluDDDDgSEP9OwCQHKuAnY_708PNfYABm8itCDcknrW4EMb3mtlo2bcNtsw&_hsmi=348788691&utm_content=348788691&utm_source=hs_email

Long-term outcomes and the future of extracorporeal care

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00416-8/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_sccm25&_hsenc=p2ANqtz--QF9CkqMJq3EC08Y_y5ptk0rsuZvBubU055Woe00n6ND4O43TDSR3d5gpod_KXkb875QvjhkfVnIzlU-shGJpWFLsi8Q&_hsmi=348788691&utm_content=348788691&utm_source=hs_email

Perioperative lung expansion and pulmonary outcomes after open abdominal surgery versus usual care in the USA (PRIME-AIR): a multicentre, randomised, controlled, phase 3 trial

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00040-2/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_sccm25&_hsenc=p2ANqtz-8aRim7U2iUtcq5e6kP82mjH5q7EcuPgm8kUDo1J40JVbLcMH9Xig59rAbZzLiADq2Xm0-XV1PTt_GCauip4gE2cz-BKQ&_hsmi=348788691&utm_content=348788691&utm_source=hs_email

In-hospital outcomes and 6-month follow-up results of patients supported with extracorporeal membrane oxygenation for COVID-19 from the second wave to the end of the pandemic (EuroECMO-COVID): a prospective, international, multicentre, observational study

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00369-2/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_sccm25&_hsenc=p2ANqtz--vQG84ReaNC7F21m44AVhmlPmq8xbg_ARLlr3e2HvC0vLFIjeYP1wg8pWwJeihxaAHOBo9FDr-b01tYL3N9zVOT8SoSQ&_hsmi=348788691&utm_content=348788691&utm_source=hs_email

Kyverna Therapeutics tests CAR T cells for autoimmune disease Rheumatologist James Chung leads efforts to expand CAR T cell therapy beyond the oncology field.

https://www.drugdiscoverynews.com/kyverna-therapeutics-tests-car-t-cells-for-autoimmune-disease-15972?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-88PMc42yd4imwfL_MntE6YMvMyGUqhXNQCOksUaljKYvvSTmTMLQj8iysguYdv1HjTEmtjFhDd3Y8u7FeukX0m5MJA3A&_hsmi=349107421&utm_content=349107421&utm_source=hs_email

Viral reactivation may cause CAR T cell-induced neurotoxicity CAR T cell therapies use engineered T cells to fight cancer, but they can sometimes cause neurotoxic side effects. Herpes virus reactivation in donor CAR T cells may be to blame

https://www.drugdiscoverynews.com/viral-reactivation-may-cause-car-t-cell-induced-neurotoxicity-15530?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--JtoklwBj2HQ2m8kFiszyje7OpzliVOtHraM1D4h8s45ZzljGWW9OLQtQbQSnNa9cJuddmu-amrcBlzk7hMIZr-PR_xA&_hsmi=349107421&utm_content=349107421&utm_source=hs_email

T cells nibble at CAR T cells to gain antitumor immunity Researchers revealed for the first time that CAR T cells can transfer their CAR molecules to regular T cells in a process known as trogocytosis.

https://www.drugdiscoverynews.com/t-cells-nibble-at-car-t-cells-to-gain-antitumor-immunity-16246

Advancing immuno-oncology with high-plex Xenium In Situ

https://pages.10xgenomics.com/web-2024-10-mkt-lit-xen-io-promo-content-hub_lp.html?&src=display&lss=drug-discovery-news&utm_term=dis-ddn-2025-02-mkt-lit-xen-xenium-io-promo-pii-enewsletter-8508&useroffertype=marketing-literature&cnm=701VI00000TBHzYYAX&cid=701VI00000TBHzYYAX&usercampaignid=701VI00000TBHzYYAX&utm_campaign=701VI00000TBHzYYAX&utm_medium=display&_hsenc=p2ANqtz-9bVdizWK9FvYuf0JlCaGaEpMlOJJ0vdIuEQrwA2Jj4BIcoR8jgnBXhmenTr6GdPHNJObafubay1h9WbhpYBwoZjgwXIg&_hsmi=349107421&utm_content=marketing-literature&utm_source=drug-discovery-news

Can you trust TikTok for nutrition advice? Study exposes #WhatIEatinaDay

https://www.news-medical.net/news/20250226/Can-you-trust-TikTok-for-nutrition-advice-Study-exposes-WhatIEatinaDay.aspx

miércoles, 26 de febrero de 2025

Do you have high LDL? If so, you may be eligible for a research study This study is evaluating an investigational drug to see whether it is safe and effective in reducing the risk of major adverse cardiovascular events in participants at high cardiovascular risk.

https://www.merckclinicaltrials.com/trial/nct06008756/?utm_source=familyheart&utm_medium=digital&utm_campaign=coralreefadvocacy&utm_term=cc

Bone marrow transplant protects mice from sickle cell–mediated large artery remodeling

https://www.science.org/doi/10.1126/scitranslmed.adp7690

Early sickle cell disease intervention may lower stroke risk

Early sickle cell disease intervention may lower stroke risk: Early sickle cell disease intervention may lower stroke risk Science Highlights February 26, 2025

Spatial -omics and metabolomics in one Scientists coupled mass spectrometry imaging with spatial transcriptomics in a single tissue, allowing for new discoveries in rare samples.

https://www.drugdiscoverynews.com/spatial-omics-and-metabolomics-in-one-15914?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-93fFrmd8cMtRSQvSJvcKeTuM00jXtujWst6uyDUqASPXYbIRkusxzfKUMdBgfWwIskiBcaf76-gpGsYQC_HT8QUO1faw&_hsmi=348927631&utm_content=348927631&utm_source=hs_email

The metabolites that define a bad night’s sleep The link between metabolism and sleep is helping scientists find new biomarkers to detect sleepless nights and diagnose chronic sleep disorders.

https://www.drugdiscoverynews.com/the-metabolites-that-define-a-bad-night-s-sleep-16158?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_hRBOvC5hKFxS7p_JMzmHYkbqfTnvwQSqbSxN2KcwGQuAMDAvL0j_uErAqkCy89WFzH_c12G3USdiZhN1pg1w_lWUshw&_hsmi=348927631&utm_content=348927631&utm_source=hs_email

A gut microbe for curbing sugar cravings Targeting a gut bacterial species or its metabolites could potentially improve diabetes management by reducing sugar preferences.

https://www.drugdiscoverynews.com/a-gut-microbe-for-curbing-sugar-cravings-16241

Predicting postpartum depression during pregnancy Levels of neuroactive steroids during the third trimester of pregnancy may indicate postpartum depression risk.

https://www.drugdiscoverynews.com/predicting-postpartum-depression-during-pregnancy-16242

Metastatic Prostate Cancer | Prenatal Blood Test | Nivolumab via Injection, 02/26/2025

https://content.govdelivery.com/accounts/USNIHNCI/bulletins/3d40d00?reqfrom=share

National Kidney Month 2025

https://www.niddk.nih.gov/health-information/community-health-outreach/national-kidney-month?utm_campaign=nkm+2025&utm_medium=niddk+e-mail&utm_source=Health%20Information%20News

Gallbladder Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/gallbladder/hp/gallbladder-treatment-pdq?cid=eb_govdel#top

Esophageal Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/esophageal/hp/esophageal-treatment-pdq?cid=eb_govdel#top

Gastric Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/stomach/hp/stomach-treatment-pdq?cid=eb_govdel#top

Hodgkin Lymphoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/lymphoma/hp/adult-hodgkin-treatment-pdq?cid=eb_govdel#top

Non-Small Cell Lung Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq?cid=eb_govdel#top

Ovarian Borderline Tumors Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/ovarian/hp/ovarian-borderline-tumors-treatment-pdq?cid=eb_govdel#top

Scratching and allergic skin inflammation

https://www.nih.gov/news-events/nih-research-matters/scratching-allergic-skin-inflammation

Creating an artificial sense of touch

https://www.nih.gov/news-events/nih-research-matters/creating-artificial-sense-touch

Therapy boosts peanut tolerance in allergic kids

https://www.nih.gov/news-events/nih-research-matters/therapy-boosts-peanut-tolerance-allergic-kids

Can AI Help Predict Which Cancer Patients Should Be Treated with Immunotherapy?

https://www.cancer.gov/news-events/cancer-currents-blog/2025/ai-predicts-cancer-immunotherapy-response-survival?cid=eb_govdel

PDQ Updates for Health Professionals +++++++++++ National Cancer Institute

Adult Treatment Acute Lymphoblastic Leukemia Treatment Acute Lymphoblastic Leukemia Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/leukemia/hp/adult-all-treatment-pdq?cid=eb_govdel#top Acute Myeloid Leukemia Treatment Acute Myeloid Leukemia Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/leukemia/hp/adult-aml-treatment-pdq?cid=eb_govdel#top Adult Central Nervous System Tumors Treatment Adult Central Nervous System Tumors Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/brain/hp/adult-brain-treatment-pdq?cid=eb_govdel#top Agnostic Cancer Therapies Agnostic Cancer Therapies (PDQ®)–Health Professional Version https://www.cancer.gov/about-cancer/treatment/types/agnostic-cancer-therapies-hp-pdq?cid=eb_govdel#top Anal Cancer Treatment Anal Cancer Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/anal/hp/anal-treatment-pdq?cid=eb_govdel#top Bile Duct Cancer (Cholangiocarcinoma) Treatment Bile Duct Cancer (Cholangiocarcinoma) Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/liver/hp/bile-duct-treatment-pdq?cid=eb_govdel#top Bladder Cancer Treatment Bladder Cancer Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/bladder/hp/bladder-treatment-pdq?cid=eb_govdel#top Breast Cancer Treatment Breast Cancer Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/breast/hp/breast-treatment-pdq?cid=eb_govdel#top Cervical Cancer Treatment Cervical Cancer Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/cervical/hp/cervical-treatment-pdq?cid=eb_govdel#top Colon Cancer Treatment Colon Cancer Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/colorectal/hp/colon-treatment-pdq?cid=eb_govdel#top Endometrial Cancer Treatment Endometrial Cancer Treatment (PDQ®)–Health Professional Version https://www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq?cid=eb_govdel#top

martes, 25 de febrero de 2025

Eli Lilly to lower price of Zepbound vials, offer more doses Company looks to draw patients away from cheap, compounded copies of weight loss medications

https://www.statnews.com/2025/02/25/eli-lilly-zepbound-weight-loss-vials/

‘Ultra-processed food’ is too broad a term to be useful The lack of clarity makes it difficult to understand any health risks

https://www.statnews.com/2025/02/25/ultra-processed-food-upf-definition-laws-maha/

What academic research could learn from college athletics Just as college sports have had to change, so does basic science research at universities

https://www.statnews.com/2025/02/25/academic-research-bayh-dole-act-indirect-costs-athletics/

Psychosocial impact associated with a multicancer early detection test (PATHFINDER): a prospective, multicentre, cohort study

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00645-4/abstract?utm_campaign=infocusalerts-psychiatry&utm_medium=email&dgcid=hubspot_email_infocusalerts-psychiatry_feature&_hsenc=p2ANqtz-__E8QBv48R62CUTTPnQcXiVjxZh-LexKWTZVhhxtFivo-HDy4T1weKLf578l0t6jHuyDmr7i9dQ3uRbspDjzcX4w8NXQ&_hsmi=348473743&utm_content=347786313&utm_source=hs_email

Comparative effectiveness of antipsychotic treatment strategies for relapse prevention in first-episode schizophrenia in Finland: a population-based cohort study

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(24)00366-3/fulltext?dgcid=hubspot_email_infocusalerts-psychiatry_feature&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz--wcQ3VvwIS-Zr56J0Pg8bY2HxYcB8TK-OE3W2p8gPPTgqe6VvKXUvymTsODJBmtKc362cEXVWrTPh_rIUZOO23JN4vLQ&_hsmi=348473743&utm_content=347786313&utm_source=hs_email

Climate change and NTDs: a perfect storm The Lancet Global Health

https://www.thelancet.com/journals/langlo/issue/vol13no2/PIIS2214-109X(25)X0002-4

Associations between childhood trauma and adolescent psychiatric disorders in Brazil: a longitudinal, population-based birth cohort study

https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(24)00452-2/fulltext?dgcid=hubspot_email_infocusalerts-psychiatry_feature&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz--hnuLuY3RHjOXI0Vj_e7-KrKezk_wpdoEZZT9y2Hm_XwBN4NgsjFugaPtAmS7GGNtovPQUioQ6GNxQXqRV3Jk2NJC5RQ&_hsmi=348473743&utm_content=347786313&utm_source=hs_email

NICE Backs New Drug Combo for Acute Lymphoblastic Leukaemia Dr Sheena Meredith February 24, 2025

https://www.medscape.com/viewarticle/nice-backs-new-drug-combo-acute-lymphoblastic-leukaemia-2025a10004r6

Do We Need to Change the 'Old Ways' of Dying? Manuela Callari February 24, 2025

https://www.medscape.com/viewarticle/do-we-need-change-old-ways-dying-2025a10004p2

How Do Medicare Beneficiaries With Advanced Cancer Receive End-of-Life Care? Edited by Katie Lennon February 24, 2025

https://www.medscape.com/viewarticle/how-do-medicare-beneficiaries-advanced-cancer-receive-end-2025a10004ol

How Do Antibody-Drug Conjugates Affect Safety and Quality of Life in Metastatic Breast Cancer? Edited by Gargi Mukherjee February 24, 2025

https://www.medscape.com/viewarticle/how-do-antibody-drug-conjugates-affect-safety-and-quality-2025a10004fe

Can Radiation Dose to Tongue Mucosa Predict Taste Loss in Head, Neck Cancer? Edited by Gargi Mukherjee February 25, 2025

https://www.medscape.com/viewarticle/can-radiation-dose-tongue-mucosa-predict-taste-loss-head-2025a10004s4

RSV Triggers Autoimmune Haemolytic Anaemia in Young Woman Dr Doris Maugg February 25, 2025

https://www.medscape.com/viewarticle/rsv-triggers-autoimmune-haemolytic-anaemia-young-woman-2025a10004rw

Pain in Cancer Survivors Linked to Higher Tobacco and Cannabis Use Edited by Katie Lennon February 25, 2025

https://www.medscape.com/viewarticle/pain-cancer-survivors-linked-higher-tobacco-and-cannabis-use-2025a10004sf

How Oncologists Can Help Breast Cancer Survivors Cope With Fear of Recurrence Marc Hogan February 25, 2025

https://www.medscape.com/viewarticle/how-oncologists-can-help-breast-cancer-survivors-cope-fear-2025a10004t2

High in the Andes, a Possible Clue Into Blood Cancer Emerges Randy Dotinga February 25, 2025

https://www.medscape.com/viewarticle/high-andes-possible-clue-blood-cancer-emerges-2025a10004sk

Race and evolution: Lumpers, splitters and health care Chuck Dinerstein | February 25, 2025

https://geneticliteracyproject.org/2025/02/25/race-and-evolution-lumpers-splitters-and-health-care/?mc_cid=d48a1187a5&mc_eid=b73600b7ac

CRISPR treatments offer hope for children with rare genetic disorders Rob Stein | NPR | February 25, 2025

https://geneticliteracyproject.org/2025/02/25/crispr-treatments-offer-hope-for-children-with-rare-genetic-disorders/?mc_cid=d48a1187a5&mc_eid=b73600b7ac

ASCO Updates Treatment Guidance for Newly Diagnosed, Advanced Ovarian Cancer Christos Evangelou, MSc, PhD February 24, 2025

https://www.medscape.com/viewarticle/asco-updates-treatment-guidance-newly-diagnosed-advanced-2025a10004ox

Stimulating mice brains with focused ultrasound changes behavioral responses to pain

Stimulating mice brains with focused ultrasound changes behavioral responses to pain: Stimulating mice brains with focused ultrasound changes behavioral responses to pain Science Highlights February 13, 2025 Transcranial focused ultrasound (tFUS) is a promising technique for non-invasive brain stimulation. By transmitting low-intensity ultrasound waves, tFUS can target deep brain regions with potentially greater precision than other forms of non-invasive brain stimulation. As the brain is involved in pain processing and perception, researchers want to learn whether targeting specific brain structures with tFUS stimulation can potentially change how the brain processes pain. In a preclinical study published in Blood, a collaborative research team designed a new multi-element ultrasound device to target specific brain regions in mice that process pain. The researchers used a genetically engineered mouse model of sickle-cell disease, a painful human condition characterized by sickle-cell shaped red blood cells. This condition leads to heightened sensitivity to different types of pain and was chosen to determine if this ultrasound approach could impact sensitivity to pain. Treatment with the new device showed a significant decrease in pain hypersensitivity, particularly in response to heat-induced pain in the mouse model. https://pubmed.ncbi.nlm.nih.gov/38976875/

lunes, 24 de febrero de 2025

Most plant-based restaurant meals are unhealthy, study finds

https://www.news-medical.net/news/20250223/Most-plant-based-restaurant-meals-are-unhealthy-study-finds.aspx

Vancomycin could offer new therapeutic option for patients with a type of inflammatory bowel disease

https://www.news-medical.net/news/20250210/Vancomycin-could-offer-new-therapeutic-option-for-patients-with-a-type-of-inflammatory-bowel-disease.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=gastroenterology_newsletter_17_february_2025

Innovative method sheds light on the proteins behind gut health

https://www.news-medical.net/news/20250205/Innovative-method-sheds-light-on-the-proteins-behind-gut-health.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=gastroenterology_newsletter_17_february_2025

New drug class may help alleviate IBS symptoms by targeting the central nervous system

https://www.news-medical.net/news/20250205/New-drug-class-may-help-alleviate-IBS-symptoms-by-targeting-the-central-nervous-system.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=gastroenterology_newsletter_17_february_2025

Oral vancomycin induces PSC-IBD remission, driving gut microbiome and metabolic shifts

https://www.news-medical.net/news/20250213/Oral-vancomycin-induces-PSC-IBD-remission-driving-gut-microbiome-and-metabolic-shifts.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=gastroenterology_newsletter_17_february_2025

Mediterranean diet boosts quality of life—here’s how

https://www.news-medical.net/news/20250210/Mediterranean-diet-boosts-quality-of-lifee28094heree28099s-how.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=gastroenterology_newsletter_17_february_2025

A gene therapy for chronic pain Researchers identified a peptide that selectively blocks pain signaling in sensory neurons and packaged it into a viral-based gene therapy in a step towards treating chronic pain without the risk for addiction.

https://www.drugdiscoverynews.com/a-gene-therapy-for-chronic-pain-15866?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-8z7zbasRk7xXts03GpEr31ukYxgwzUY8aG_BHldHRjMkqXUR9qP9j9Us193jCVlxne-F4K9J1seamL6_Bjn5Bm5w9Y8w&_hsmi=348417667&utm_content=348417667&utm_source=hs_email

Manipulating nerves to relieve pain without drugs Seeking alternatives to pharmacological approaches, researchers apply thermal, electrical, and mechanical stimuli to change nerve signaling and treat pain.

https://www.drugdiscoverynews.com/manipulating-nerves-to-relieve-pain-without-drugs-15553?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_yQOSv6dPlQbneS_bqenbB1Jsowze3Yw1shATe27O5nOu9qhOvB5yQh3T-V77lb1h2WuqIBK8mppOJayxC967HoheaEg&_hsmi=348417667&utm_content=348417667&utm_source=hs_email

A unique antidepressant may provide a new avenue to pain relief Researchers studied an antidepressant that may help treat neuropathic pain.

https://www.drugdiscoverynews.com/a-unique-antidepressant-may-provide-a-new-avenue-to-pain-relief-16137?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9suhLJgMZzaMRqtRrVIcoziMkAFRzv2tGTf6YzrWTUpqHnrI68TyPsNPAfJgkabAYSVZ69WYo6nNYNY9hTCkN9MMZnWg&_hsmi=348417667&utm_content=348417667&utm_source=hs_email

A new migraine medication is on the horizon Lundbeck Therapeutics is testing a monoclonal antibody that targets a novel neuropeptide in a Phase 2b clinical trial.

https://www.drugdiscoverynews.com/a-new-migraine-medication-is-on-the-horizon-16238

What diagnostic tests can teach about spotting public fraud It all comes down to sensitivity and specificity

https://www.statnews.com/2025/02/24/diagnostic-tests-fraud-waste-government-doge-specificity-sensitivity/

We bought all these illegal products in the FDA’s backyard

Secret shoppers went to NY’s unlicensed dispensaries Unlicensed dispensaries and smoke shops are significantly less likely than licensed retailers to require age verification before somebody enters a store or makes a purchase, according to a secret shopper study published today in Pediatrics. Shoppers went to 37 dispensaries and smoke shops in New York City, also finding that unlicensed stores more often sold products that appeal to young people like energy drinks, soda, and candy. Part of the point of legalizing weed is to reduce risk through regulation, the authors write. But in New York, unlicensed retailers outnumber the licensed, regulated ones. In a First Opinion essay last year, three researchers and advocates wrote that, “implementing strong and comprehensive protections for children is not the norm in many states that have legalized recreational marijuana use.” And because we’re talking about how easy it can be to get illegal drugs, I must once again remind you of this iconic STAT video. https://www.statnews.com/2024/06/05/as-states-legalize-recreational-marijuana-use-for-adults-they-must-prioritize-protecting-kids/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9OW7sqi944emy25T5XDaZg34UGnCzNby6J-3xqPV3UqaurcpspED5LHktYPNBUKzcFqpwVTMnn-XxdxaeXLcDNNGSnjw&_hsmi=348565801&utm_content=348565801&utm_source=hs_email Cannabis Access by Retailer Type in New York https://publications.aap.org/pediatrics/article-abstract/155/3/e2024068669/201048/Cannabis-Access-by-Retailer-Type-in-New-York?redirectedFrom=fulltext

Social Factors, Age, and Health at Time of Dementia Diagnosis

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2830594?guestAccessKey=02aaa416-168d-4a8f-90d5-dbbb5c13cf3e&utm_term=022125&utm_campaign=ftm_links&utm_medium=referral&_hsenc=p2ANqtz-8yxcuGdktVwqdxP_-viOqUeBdMGB34mtc3oyYryj5cp8VGTKhvzCRAcAcTjxabKhYklQ3vWp5N_e9X3txItquKtchbew&_hsmi=348565801&utm_content=tfl&utm_source=for_the_media The factors influencing when people are diagnosed with dementia People with lower levels of education, who live alone or in a care home, or who don’t have a close relative, are about three years older when they receive an official dementia diagnosis compared to their counterparts, according to a study published Friday in JAMA Network Open that looked at more than 107,000 people in Sweden who were diagnosed with dementia between 2018 and 2022. On top of that, people who had less than a high school education (fewer than nine years) had more comorbidities and took more medications than those with more schooling. The results could indicate that these populations tend to have more advanced disease or a poorer prognosis, the authors write. They couldn’t say what caused the delayed diagnoses, of course, but hypothesized that the risk of losing a driver’s license may play a larger role in when to seek care for people who live alone or have fewer family members.

Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers

https://www.nature.com/articles/s41467-025-56448-y?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8ZmpJMB2sohpOu6PQ61jflMAo2caMUg5stkmd4pYlwP-j8dqVODNi1QGm4q-jFn2Hs0-cmI20_k6WBhUXTwLmsOhN-wg&_hsmi=348565801&utm_content=348565801&utm_source=hs_email Can treatments for lung conditions go deeper? Between common chronic conditions like COPD and asthma, and acute harm inflicted by viruses, lung damage is a big problem. Many treatments focus on the upper airways. But to go deeper, researchers are studying the pair found in some Covid vaccines: mRNA + a lipid nanoparticle. New research in mice, published Friday in Nature Communications, posits that a similar technology could be used to stimulate healing in parts of the lung not easily reached by conventional therapies. The team reports a nanoparticle, called ionizable amphiphilic Janus dendrimer, targets mRNA therapy directly to the lung and promotes tissue repair. “If introduced early in the inflammatory process,” this mechanism could speed up healing, “ultimately reducing the incidence of complex lung injury and disease,” write the authors (several of whom are named on patents and patent applications related to the research). — Isabella Cueto

What Are Common Types of Eating Disorders?

https://www.nimh.nih.gov/health/publications/what-are-common-types-of-eating-disorders?utm_campaign=EDAW25&utm_medium=email&utm_source=govd

Digital Shareables on Eating Disorders

https://www.nimh.nih.gov/get-involved/digital-shareables/shareable-resources-on-eating-disorders?utm_campaign=EDAW25&utm_medium=email&utm_source=govd

Publications about Eating Disorders

https://www.nimh.nih.gov/health/publications/eating-disorders-listing?utm_campaign=EDAW25&utm_medium=email&utm_source=govd

Eating Disorders: Where can I learn more about eating disorders?

https://www.nimh.nih.gov/health/topics/eating-disorders?utm_campaign=EDAW25&utm_medium=email&utm_source=govd

Eating Disorders: What You Need to Know

https://www.nimh.nih.gov/health/publications/eating-disorders?utm_campaign=EDAW25&utm_medium=email&utm_source=govd

Digital Toolkit for National Eating Disorders Awareness Week

https://www.nimh.nih.gov/get-involved/digital-toolkit-for-eating-disorders?utm_campaign=EDAW25&utm_medium=email&utm_source=govd

domingo, 23 de febrero de 2025

Two Alzheimer’s drugs help patients live independently at home for longer periods Lecanemab (Leqembi) and donanemab (Kisunla) could slow cognitive decline, but side effects exist Melissa Rudy By Melissa Rudy Fox News Published February 20, 2025 4:30am EST

Two Alzheimer’s drugs help patients live independently at home for longer periods Lecanemab (Leqembi) and donanemab (Kisunla) could slow cognitive decline, but side effects exist Melissa Rudy By Melissa Rudy Fox News Published February 20, 2025 4:30am EST https://www.foxnews.com/health/two-alzheimers-drugs-help-patients-live-independently-home-longer-periods

Flu cases by state and measles outbreak, plus concerning cancer trends And more of the top Fox News Health stories and videos from the past week By Fox News Staff Fox News Published February 19, 2025 8:32pm EST

Flu cases by state and measles outbreak, plus concerning cancer trends And more of the top Fox News Health stories and videos from the past week By Fox News Staff Fox News Published February 19, 2025 8:32pm EST https://www.foxnews.com/health/flu-cases-state-measles-outbreak-concerning-cancer-trends

To eat eggs safely, do these two things, says food science expert Amid bird flu outbreaks, eggs are safe to eat with proper practices: See the video By Khloe Quill Fox News Published February 20, 2025 1:49pm EST

To eat eggs safely, do these two things, says food science expert Amid bird flu outbreaks, eggs are safe to eat with proper practices: See the video By Khloe Quill Fox News Published February 20, 2025 1:49pm EST https://www.foxnews.com/health/eat-eggs-safely-do-two-things-says-food-science-expert

Experimental vaccine for common cancer shows potential in clinical trial Some pancreatic cancer patients showed immune response to mRNA vaccine Angelica Stabile By Angelica Stabile Fox News Published February 20, 2025 6:17pm EST

Experimental vaccine for common cancer shows potential in clinical trial Some pancreatic cancer patients showed immune response to mRNA vaccine Angelica Stabile By Angelica Stabile Fox News Published February 20, 2025 6:17pm EST https://www.foxnews.com/health/experimental-vaccine-common-cancer-shows-potential-clinical-trial

New Mexico reports Texas measles outbreak has now crossed its border Six of the eight people infected in New Mexico were unvaccinated Christina Shaw By Christina Shaw Fox News Published February 21, 2025 3:54am EST

New Mexico reports Texas measles outbreak has now crossed its border Six of the eight people infected in New Mexico were unvaccinated Christina Shaw By Christina Shaw Fox News Published February 21, 2025 3:54am EST https://www.foxnews.com/health/new-mexico-reports-texas-measles-outbreak-has-now-crossed-its-border

Common cancer treatment can have this painful side effect What to know about 'chemo mouth,' which can occur with chemotherapy Angelica Stabile By Angelica Stabile Fox News Published February 21, 2025 4:30am EST

Common cancer treatment can have this painful side effect What to know about 'chemo mouth,' which can occur with chemotherapy Angelica Stabile By Angelica Stabile Fox News Published February 21, 2025 4:30am EST https://www.foxnews.com/health/common-cancer-treatment-painful-side-effect

Is MMR vaccine safe for kids? Dr. Nicole Saphier addresses concerns as measles cases rise Dr. Nicole Saphier addresses concerns about side effects, autism and more Angelica Stabile By Angelica Stabile Fox News Published February 11, 2025 4:30am EST | Updated February 21, 2025 2:46pm EST

Is MMR vaccine safe for kids? Dr. Nicole Saphier addresses concerns as measles cases rise Dr. Nicole Saphier addresses concerns about side effects, autism and more Angelica Stabile By Angelica Stabile Fox News Published February 11, 2025 4:30am EST | Updated February 21, 2025 2:46pm EST https://www.foxnews.com/health/mmr-vaccine-safe-kids-dr-saphier-adresses-concerns-measles-cases-rise-us

Children with autism may see speech improvements with off-label prescription drug Leucovorin, a drug for cancer patients, has shown promise for autism treatment in early studies Melissa Rudy By Melissa Rudy Fox News Published February 22, 2025 4:30am EST

Children with autism may see speech improvements with off-label prescription drug Leucovorin, a drug for cancer patients, has shown promise for autism treatment in early studies Melissa Rudy By Melissa Rudy Fox News Published February 22, 2025 4:30am EST https://www.foxnews.com/health/children-autism-may-see-speech-improvements-off-label-prescription-drug

Knowing your sleep chronotype can lead to better rest and health Adapting schedules to sleep styles may optimize productivity, experts say By Amy McGorry Fox News Published February 23, 2025 4:30am EST

Knowing your sleep chronotype can lead to better rest and health Adapting schedules to sleep styles may optimize productivity, experts say By Amy McGorry Fox News Published February 23, 2025 4:30am EST https://www.foxnews.com/health/knowing-sleep-chronotype-can-lead-better-rest-health

CHILDHOOD CRISIS: HELPING KIDS THROUGH ADVERSITY & TRAUMA

Childhood Adversity: Helping Kids Through Adversity & Trauma By Ivanhoe Broadcast News on February 23, 2025 https://www.ivanhoe.com/?p=35066&preview=1&_ppp=d7508007c2

ROSIE’S SANCTUARY: ONE PERSON CAN MAKE A DIFFERENCE

Rosie’s Sanctuary: One Person Can Make a Difference By Ivanhoe Broadcast News on February 23, 2025 https://www.ivanhoe.com/positive-parenting/rosies-sanctuary-one-person-can-make-a-difference/

CONFRONTING THE FUTURE: TEEN LEADERS SPEAK OUT

Confronting The Future: Teen Leaders Speak Out By Ivanhoe Broadcast News on February 22, 2025 https://www.ivanhoe.com/positive-parenting/confronting-the-future-teen-leaders-speak-out/

A WORKFORCE REVOLUTION: NO COLLEGE NEEDED

A Workforce Revolution: No College Needed By Ivanhoe Broadcast News on February 22, 2025 https://www.ivanhoe.com/?p=35058&preview=1&_ppp=ddab12f69c

WHAT IS SUCCESS? THE GENERATIONAL DIVIDE

What Is Success? The Generational Divide By Ivanhoe Broadcast News on February 28, 2025 https://www.ivanhoe.com/?p=35081&preview=1&_ppp=a7726305a0

WHAT’S YOUR STRESS PERSONALITY?

What’s Your Stress Personality? By Ivanhoe Broadcast News on February 27, 2025 https://www.ivanhoe.com/?p=35078&preview=1&_ppp=55ec4c5875

OVERSHARING ONLINE: THINGS TO NEVER POST ON SOCIAL MEDIA

Over Sharing Online: Things To Never Post On Social Media By Ivanhoe Broadcast News on February 26, 2025 https://www.ivanhoe.com/?p=35075&preview=1&_ppp=24ce430719

MANKEEPING: THE IMPACT OF THE MALE FRIENDSHIP RECESSION

Mankeeping: The Impact Of The Male Friendship Recession By Ivanhoe Broadcast News on February 25, 2025 https://www.ivanhoe.com/?p=35072&preview=1&_ppp=5bd92961a3

THE HIGH 5 CHALLENGE: 5 MINUTE FIX FOR STRESSED OUT KIDS

The High 5 Challenge: 5 Minute Fix For Stressed Out Kids By Ivanhoe Broadcast News on February 24, 2025 https://www.ivanhoe.com/?p=35069&preview=1&_ppp=bb909f3ba9

Portable MRI, enhanced by AI, proves viable in brain imaging for dementia

Portable MRI, enhanced by AI, proves viable in brain imaging for dementia: The low image quality of small, affordable MRI machines have prevented their widespread use. But a boost from AI could close the gap, bringing MRI to more patients. Of all the instruments in the modern medicine toolbox, magnetic resonance imaging, or MRI, is one of the most powerful. But in many regions, the expense, space, and expertise required to use it puts this tool out of reach. A new study suggests that, with a performance boost from artificial intelligence (AI), existing portable, low-cost MRI tech could make high-quality brain imaging available to more patients. The new system employs AI techniques to improve the quality of, and then automatically analyze, images taken from low-field strength MRI devices that, due to being smaller, sacrifice image quality compared to conventional MRI machines. In a recent clinical study, researchers from Massachusetts General Hospital, Harvard Medical School, and Yale School of Medicine used their automated approach to detect Alzheimer’s disease markers in humans, finding that their technique performed at the same level as higher-power MRI. Their results, published in Nature Communications, point to the new method as a potential means of providing broad access to high-quality brain imaging.

Abnormal Results from Prenatal Blood Test Could Point to Cancer in the Mother

https://www.cancer.gov/news-events/cancer-currents-blog/2025/nipt-reveals-cancer-in-pregnant-women?cid=eb_govdel

sábado, 22 de febrero de 2025

Antioxidant-enzyme interactions and their role in non-communicable diseases

https://www.news-medical.net/news/20250221/Antioxidant-enzyme-interactions-and-their-role-in-non-communicable-diseases.aspx

Texas measles outbreak nears 100 cases, raising concerns about undetected spread

https://www.news-medical.net/news/20250221/Texas-measles-outbreak-nears-100-cases-raising-concerns-about-undetected-spread.aspx

Effective ways to combat head lice in schoolchildren

https://www.news-medical.net/news/20250221/Effective-ways-to-combat-head-lice-in-schoolchildren.aspx

FDA-approved devices used to treat cardiovascular diseases

https://www.news-medical.net/news/20250221/FDA-approved-devices-used-to-treat-cardiovascular-diseases.aspx

Engineered blood vessel cells boost islet transplant success in diabetes treatment

https://www.news-medical.net/news/20250221/Engineered-blood-vessel-cells-boost-islet-transplant-success-in-diabetes-treatment.aspx

Study links excessive screen time to psychological distress in adolescents

https://www.news-medical.net/news/20250221/Study-links-excessive-screen-time-to-psychological-distress-in-adolescents.aspx

Harbour BioMed partners with Insilico to accelerate AI-powered antibody discovery

https://www.news-medical.net/news/20250221/Harbour-BioMed-partners-with-Insilico-to-accelerate-AI-powered-antibody-discovery.aspx

New computational tool iDOMO improves prediction of drug synergy

https://www.news-medical.net/news/20250222/New-computational-tool-iDOMO-improves-prediction-of-drug-synergy.aspx

Study finds lack of consensus on how to treat chronic non-cancer pain

https://www.news-medical.net/news/20250222/Study-finds-lack-of-consensus-on-how-to-treat-chronic-non-cancer-pain.aspx

New genetic medicine offers life-changing vision improvements for blind children

https://www.news-medical.net/news/20250222/New-genetic-medicine-offers-life-changing-vision-improvements-for-blind-children.aspx

Workplace bullying linked to sleep problems in employees and their partners

https://www.news-medical.net/news/20250222/Workplace-bullying-linked-to-sleep-problems-in-employees-and-their-partners.aspx

How to analyze, sort and dispense single cells with picodroplets

https://www.news-medical.net/whitepaper/20250221/How-to-analyze-sort-and-dispense-single-cells-with-picodroplets.aspx

How to isolate single cells with picodroplets

https://www.news-medical.net/whitepaper/20250221/How-to-isolate-single-cells-with-picodroplets.aspx

The Truth About Mushroom Coffee: Benefits vs. Hype

https://www.news-medical.net/health/The-Truth-About-Mushroom-Coffee-Benefits-vs-Hype.aspx

Can chili peppers improve ADHD symptoms? Scientists explore their gut-brain connection

https://www.news-medical.net/news/20250220/Can-chili-peppers-improve-ADHD-symptoms-Scientists-explore-their-gut-brain-connection.aspx

Overall survival and quality of life with [177Lu]Lu-PSMA-617 plus enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer (ENZA-p): secondary outcomes from a multicentre, open-label, randomised, phase 2 trial

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00009-9/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_ascogu25&_hsenc=p2ANqtz-9bPLJ27tVEdKQhkncwYHpwYj_PKroX842t9eX7_xzt69Yix7WZGM_kQjppDapQEm0GMiz2UXs6wpeIutVCec8caDPqUQ&_hsmi=348374471&utm_content=347180122&utm_source=hs_email

Direct oral anticoagulants versus vitamin K antagonists for cerebral venous thrombosis (DOAC-CVT): an international, prospective, observational cohort study

https://www.thelancet.com/collections/neurology?dgcid=hubspot_email_infocusalerts-neurology_feature&parent=001585&startPage=&ContentItemType=fla&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-9IlgWWLsdbrD9EBWTqJ9VHPf3VaOPp6aLWVYrn24hkSO0tLJoToPjOdn4sDH45zFj168LC5tYDTJn91-PvMl38kvaDyw&_hsmi=348386757&utm_content=347785879&utm_source=hs_email

Intranasal oxytocin for apathy in people with frontotemporal dementia (FOXY): a multicentre, randomised, double-blind, placebo-controlled, adaptive, crossover, phase 2a/2b superiority trial

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00456-3/abstract?utm_campaign=infocusalerts-neurology&utm_medium=email&dgcid=hubspot_email_infocusalerts-neurology_feature&_hsenc=p2ANqtz-8xRo3Q064ozz7k5KV0zXuBNZ2Pq9zkcjJwNxVvAYoyPKpeHr3yF1ByDXgS7QSN-LkW1rblCKcAxdp5lDc8sXo0bTLiQw&_hsmi=348386757&utm_content=347785879&utm_source=hs_email

Accelerated biological aging increases the risk of short- and long-term stroke prognosis in patients with ischemic stroke or TIA

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00530-9/fulltext?dgcid=hubspot_email_infocusalerts-neurology_feature&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz--6mbw1O94wqXvWCshKfMDwGc7z2Aa1-4mhrHfnq6Hmu4q_JU-hZTTqFm3tRg0y5Af7OBqYtspKaXM_8hA7ijmsLDgDnQ&_hsmi=348386757&utm_content=347785879&utm_source=hs_email

Trajectories and social determinants of child cognitive development: a prospective cohort study from infancy through middle childhood in Dhaka, Bangladesh

https://www.thelancet.com/journals/lansea/article/PIIS2772-3682(24)00161-6/fulltext?dgcid=hubspot_email_infocusalerts-neurology_feature&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-9XhAHJHPV1K-hY-oI72L4mVbQuSPSuLd0nf-gJI4csopxxkjGR5Grp7ldM_M0RCgLYUMiufuSP6SpKwMvdTVo4SPOGZg&_hsmi=348386757&utm_content=347785879&utm_source=hs_email

viernes, 21 de febrero de 2025

Validated Tool Effective in Helping Determine Whether One Bruise on Child in ED Signals Abuse Marcia Frellick February 21, 2025

https://www.medscape.com/viewarticle/validated-tool-effective-helping-determine-whether-one-2025a10004k1

New GLP-1 Data Reinforce CV Benefit Ted Bosworth February 21, 2025

https://www.medscape.com/viewarticle/new-glp-1-data-reinforce-cv-benefit-2025a10004ki

The Surprising Source of Next-Gen Antibiotics: Oyster Blood Caitlin Taylor So February 21, 2025

https://www.medscape.com/viewarticle/surprising-source-next-gen-antibiotics-oyster-blood-2025a10004kr

Stress: A New Cancer Risk Factor? F. Perry Wilson, MD, MSCE | February 19, 2025

https://www.medscape.com/viewarticle/stress-new-cancer-risk-factor-2025a10004b8

Excessive Drinking Raises Heart Disease Risk Edited by Archita Rai February 20, 2025

https://www.medscape.com/viewarticle/excessive-drinking-raises-heart-disease-risk-2025a10004es

New Five-Type Index Provides Doctors Guide for Long COVID David Brzostowicki February 20, 2025

https://www.medscape.com/viewarticle/new-five-type-index-provides-doctors-guide-long-covid-2025a10004gd

Intravenous Thrombolysis in Patients Taking Direct Oral Anticoagulation Treatment Before Stroke Onset: Results from the Safe Implementations of Treatments in Stroke International Stroke Registry.

https://read.qxmd.com/read/39902556/intravenous-thrombolysis-in-patients-taking-direct-oral-anticoagulation-treatment-before-stroke-onset-results-from-the-safe-implementations-of-treatments-in-stroke-international-stroke-registry?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Association of Alcohol and Incremental Cardiometabolic Risk Factors with Liver Disease: A National Cross-Sectional Study.

https://read.qxmd.com/read/39909281/association-of-alcohol-and-incremental-cardiometabolic-risk-factors-with-liver-disease-a-national-cross-sectional-study?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Association of Insomnia, Lipid Profile, and Lipid-Lowering Medications: A Narrative Review.

https://read.qxmd.com/read/39867194/association-of-insomnia-lipid-profile-and-lipid-lowering-medications-a-narrative-review?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Finerenone: Will It Be a Game-changer?

https://read.qxmd.com/read/39872849/finerenone-will-it-be-a-game-changer?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Randomized Comparison of Magnetic Resonance Imaging Versus Transurethral Resection for Staging New Bladder Cancers: Results From the Prospective BladderPath Trial.

https://read.qxmd.com/read/39808757/randomized-comparison-of-magnetic-resonance-imaging-versus-transurethral-resection-for-staging-new-bladder-cancers-results-from-the-prospective-bladderpath-trial?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Sepsis-Associated Acute Kidney Injury: Pathophysiology and Treatment Modalities.

https://read.qxmd.com/read/39834999/sepsis-associated-acute-kidney-injury-pathophysiology-and-treatment-modalities?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Nanobots: The current scenario.

https://read.qxmd.com/read/39929350/nanobots-the-current-scenario?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Jujuboside B inhibits proliferation and induces apoptosis and ferroptosis in colorectal cancer cells with potential involvement of the MAPK signaling pathway.

https://read.qxmd.com/read/39911154/jujuboside-b-inhibits-proliferation-and-induces-apoptosis-and-ferroptosis-in-colorectal-cancer-cells-with-potential-involvement-of-the-mapk-signaling-pathway?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Real-world effectiveness and safety of rituximab and reduced-dose CHP with polatuzumab vedotin (pola-R-CHP) in patients aged > 80 years with diffuse large B-cell lymphoma: a retrospective analysis.

https://read.qxmd.com/read/39907880/real-world-effectiveness-and-safety-of-rituximab-and-reduced-dose-chp-with-polatuzumab-vedotin-pola-r-chp-in-patients-aged-80-years-with-diffuse-large-b-cell-lymphoma-a-retrospective-analysis?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Targeting Caseinolytic Mitochondrial Matrix Peptidase, a Novel Contributor to High-risk Behavior, in Multiple Myeloma.

https://read.qxmd.com/read/39912779/targeting-caseinolytic-mitochondrial-matrix-peptidase-a-novel-contributor-to-high-risk-behavior-in-multiple-myeloma?uac=148436CN&ecd=wnl_readmost_250221&sso=true&redirected=slug

Most Read Papers - Cancer Science & Oncogenesis

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_250221

The Whole Person Health Index: An Integrated Self-Reported Measure Capturing Essential Components of Health

https://www.nccih.nih.gov/research/blog/the-whole-person-health-index-an-integrated-self-reported-measure-capturing-essential-components-of-health?nav=govd

Is it time to rethink how we measure success in immunotherapy?

https://www.statnews.com/sponsor/2024/12/13/is-it-time-to-rethink-how-we-measure-success-in-immunotherapy/

jueves, 20 de febrero de 2025

Lower Your COPD Risk at Any Age

February is American Heart Month ++++++

https://www.nhlbi.nih.gov/education/american-heart-month?utm_source=govdelivery&utm_medium=email&utm_campaign=nhlbi-update-february2025&utm_term=version-a Building digital twins and hearts https://www.nhlbi.nih.gov/news/2025/building-digital-twins-and-hearts?utm_source=govdelivery&utm_medium=email&utm_campaign=nhlbi-update-february2025&utm_term=version-a NIH study finds infection-related hospitalizations linked to increased risk of heart failure https://www.nhlbi.nih.gov/news/2025/nih-study-finds-infection-related-hospitalizations-linked-increased-risk-heart-failure?utm_source=govdelivery&utm_medium=email&utm_campaign=nhlbi-update-february2025&utm_term=version-a What Are Bleeding Disorders? Fact Sheet https://www.nhlbi.nih.gov/resources/what-are-bleeding-disorders-fact-sheet?utm_source=govdelivery&utm_medium=email&utm_campaign=nhlbi-update-february2025&utm_term=version-a Anemia at a Glance Infographic https://www.nhlbi.nih.gov/resources/anemia-glance-infographic?utm_source=govdelivery&utm_medium=email&utm_campaign=nhlbi-update-february2025&utm_term=version-a Take Action for Your Heart: Get Started! Fact Sheet https://www.nhlbi.nih.gov/resources/take-action-your-heart-get-started-fact-sheet?utm_source=govdelivery&utm_medium=email&utm_campaign=nhlbi-update-february2025&utm_term=version-a

As key ally of RFK. Jr., contoversial Environmental Working Group lobbyist is poised to help steer American health, food and agriculture policy Jesse Newman | Wall Street Journal | February 19, 2025

https://geneticliteracyproject.org/2025/02/19/as-key-ally-of-rfk-jr-contoversial-environmental-working-group-lobbyist-is-poised-to-help-steer-american-health-food-and-agriculture-policy/?mc_cid=71245d279b&mc_eid=b73600b7ac

Viewpoint: Activist Food and Water Watch offers its blueprint of what RFK, Jr. should do to ‘reform’ America’s food system Rebecca Wolf | Food & Water Watch | February 20, 2025

https://geneticliteracyproject.org/2025/02/20/viewpoint-activist-food-and-water-watch-offers-its-blueprint-of-what-rfk-jr-should-do-to-reform-americas-food-system/?mc_cid=71245d279b&mc_eid=b73600b7ac

Vegetable and seed oils vs. Animal fat oil: Which Is the healthy choice Caroline Kee | Today | February 20, 2025

https://geneticliteracyproject.org/2025/02/20/vegetable-and-seed-oils-vs-animal-fat-oil-which-is-the-healthy-choice/?mc_cid=71245d279b&mc_eid=b73600b7ac

Viewpoint: Here is what Trump’s order banning federal support for transcare gets wrong about the science of gender dysphoria Oscar Taube | Baltimore Sun | February 19, 2025

https://geneticliteracyproject.org/2025/02/19/viewpoint-here-is-what-trumps-order-banning-federal-support-for-transcare-gets-wrong-about-the-science-of-gender-dysphoria/?mc_cid=71245d279b&mc_eid=b73600b7ac

Risky business: How human’s evolutionary response to danger has left all of us vulnerable Simon Ings | New Scientist | February 19, 2025

https://geneticliteracyproject.org/2025/02/19/risky-business-how-humans-evolutionary-response-to-danger-has-left-all-of-us-vulnerable/?mc_cid=71245d279b&mc_eid=b73600b7ac

Wil IVF soon become a protected right under President Trump’s executive order? Sort of and maybe Andrew Romano | Yahoo News | February 20, 2025

https://geneticliteracyproject.org/2025/02/20/wil-ivf-soon-become-a-protected-right-under-president-trumps-executive-order-sort-of-and-maybe/?mc_cid=71245d279b&mc_eid=b73600b7ac

The US fertility rate continues to fall sharply. Once celebrated, this trend could portend economic disaster. Here’s why Jesús Fernández-Villaverde | American Enteprise Institute | February 20, 2025

https://geneticliteracyproject.org/2025/02/20/the-us-fertility-rate-continues-to-fall-sharply-once-celebrated-this-trend-could-portend-economic-disaster-heres-why/?mc_cid=71245d279b&mc_eid=b73600b7ac

GLP-1 miracle elixirs? Add reducing cravings for drugs and alcohol to the already long list of health benefits linked to weight loss drugs Dani Blum | New York Times | February 20, 2025

https://geneticliteracyproject.org/2025/02/20/glp-1-miracle-elixirs-add-reducing-cravings-for-drugs-and-alcohol-to-the-already-long-list-of-health-benefits-linked-to-weight-loss-drugs/?mc_cid=71245d279b&mc_eid=b73600b7ac

Fat… and yet fit? Here’s the skinny Chuck Dinerstein | February 20, 2025

https://geneticliteracyproject.org/2025/02/20/fat-and-yet-fit-heres-the-skinny/?mc_cid=71245d279b&mc_eid=b73600b7ac

Eat this, not that: The best (and worst) foods for longevity

https://www.news-medical.net/news/20250219/Eat-this-not-that-The-best-(and-worst)-foods-for-longevity.aspx

New hope to relieve dryness and fatigue in Sjögren’s disease Novartis’ iscalimab may improve troubling symptoms in patients with Sjögren’s disease, though there may be safety concerns to address.

https://www.drugdiscoverynews.com/new-hope-to-relieve-dryness-and-fatigue-in-sj-gren-s-disease-16161?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9mq-YmmsYOixuNoZsXR_fqn_q7uGhu--_xbdArSpbp8ThLiJeDKRcjbBK3oKWr6sE-rZ-zELJBrIruyR6VGTSajJIxCA&_hsmi=348091523&utm_content=348091523&utm_source=hs_email

Addressing sex differences in autoimmune diseases Susan Kovats explores the role of sex hormones in autoimmunity to guide the development of therapeutics for lupus, Sjögren’s syndrome, and other diseases that preferentially affect women.

https://www.drugdiscoverynews.com/addressing-sex-differences-in-autoimmune-diseases-15559?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--VEQKZcyuG2-0P2pt62I0UYdfXT6BIn3V-ginX64hyojVnJ7NTylk13-gLfsiMNyjH3IWFLEL9P5DeVsRfbMA9VO3Veg&_hsmi=348091523&utm_content=348091523&utm_source=hs_email

Diagnostics for faster antimicrobial susceptibility testing New phenotypic methods can help identify the best antibiotic to treat sepsis, UTIs, and other bacterial infections.

https://www.drugdiscoverynews.com/diagnostic-for-faster-antimicrobial-susceptibility-testing-16233

Crohn’s disease complication linked to metal-hungry E. coli A strain of E. coli linked to Crohn’s disease produces a compound that triggers intestinal scarring, revealing a potential treatment path.

https://www.drugdiscoverynews.com/crohn-s-disease-complication-linked-to-metal-hungry-e-coli-16234

Amgen drug blocks immune chitchat that drives Sjögren’s disease As a CD40 ligand antagonist, dazodalibep blocks immune cell communication, potentially serving as the first drug to target the autoimmune disease’s cause.

https://www.drugdiscoverynews.com/amgen-drug-blocks-immune-chitchat-that-drives-sj-gren-s-disease-16235

Infographic: Six Tips To Make Mealtimes Easier for People With Alzheimer’s Disease

https://www.nia.nih.gov/health/alzheimers-caregiving/six-tips-make-mealtimes-easier-people-alzheimers-disease?&utm_source=nia-eblast&utm_medium=email&utm_campaign=general-20250220?&utm_source=nia-eblast&utm_medium=email&utm_campaign=general-20250130

Palliative Care in Emergency Departments: Addressing the Needs of Seriously Ill Older Adults

https://www.nccih.nih.gov/research/research-results/palliative-care-in-emergency-departments-addressing-the-needs-of-seriously-ill-older-adults?nav=govd Among people aged 65 and older, half visited the emergency department (ED) in the last month of their lives, and three in four visited the ED during the 6 months before their deaths. However, emergency care has not adapted to meet these patients’ needs, with palliative care teams, present in two-thirds of hospitals, not typically available in EDs for crisis response. A new study, published in the Journal of the American Medical Association and conducted by researchers from Memorial Sloan Kettering Cancer Center, New York University Grossman School of Medicine, and Tibor Rubin Long Beach Veterans Affairs, evaluates the effect of a multicomponent intervention to initiate palliative care in the ED on hospital admission rates for older adults with serious, life-limiting illnesses. This research was supported by the National Center for Complementary and Integrative Health and other components of the National Institutes of Health (NIH) within the NIH Pragmatic Trials Collaboratory.

Shared Testimony in Palliative Care: Richard's Story

Patient Stories: How Palliative Care Helps with Anxiety, Pain, and More https://getpalliativecare.org/patient-stories-how-palliative-care-helps-with-anxiety-pain-and-more/?utm_source=Get+Palliative+Care&utm_campaign=999c913f9b-GPC+%2F+2.19.25&utm_medium=email&utm_term=0_4ef32a103e-999c913f9b-378264050

FDA Approves Injectable Nivolumab, an Alternative to IV Infusion

https://www.cancer.gov/news-events/cancer-currents-blog/2025/fda-opdivo-injection?cid=eb_govdel

miércoles, 19 de febrero de 2025

Dynamic functional adaptations during touch observation in autism: connectivity strength is linked to attitudes towards social touch and social responsiveness

https://molecularautism.biomedcentral.com/

Featured Article: Validation of an web-based dietary assessment tool (RiksmatenFlex) against doubly labelled water and 24 h dietary recalls in pregnant women

https://nutritionj.biomedcentral.com/

Featured article: Adherence to the Eatwell Guide and cardiometabolic, cognitive and neuroimaging parameters: an analysis from the PREVENT dementia study

https://nutritionandmetabolism.biomedcentral.com/

Assessment of a multi-ingredient dietary supplement on sleep quality: a randomized, double-blinded, placebo-controlled crossover clinical study

https://sleep.biomedcentral.com/

Substance Abuse Treatment, Prevention, and Policy

https://substanceabusepolicy.biomedcentral.com/

A multistage double-blind placebo-controlled study to assess the safety and efficacy of transdermal vitamin D phosphate supplementation (TransVitD)

https://trialsjournal.biomedcentral.com/

Differentially localizing isoforms of the migraine component calcitonin gene-related peptide (CGRP), in the mouse trigeminal ganglion: βCGRP is translated but, unlike αCGRP, not sorted into axons

https://thejournalofheadacheandpain.biomedcentral.com/

High-salt diet decreases FOLFOX efficacy via gut bacterial tryptophan metabolism in colorectal cancer

https://molmed.biomedcentral.com/

The impact of regular sauerkraut consumption on the human gut microbiota: a crossover intervention trial

https://microbiomejournal.biomedcentral.com/

IDO1 modulates pain sensitivity and comorbid anxiety in chronic migraine through microglial activation and synaptic pruning

https://jneuroinflammation.biomedcentral.com/

CX3CR1+ age-associated CD4+ T cells contribute to synovial inflammation in late-onset rheumatoid arthritis

https://inflammregen.biomedcentral.com/

Alpha-1 antitrypsin reduces inflammation and vasculopathy in mice with oxygen-induced retinopathy

https://journal-inflammation.biomedcentral.com/

The role of platelets in cancer: from their influence on tumor progression to their potential use in liquid biopsy

https://biomarkerres.biomedcentral.com/

Featured Article: Sex differences in cognition, anxiety-phenotype and therapeutic effect of metformin in the aged apoE-TR mice

https://bsd.biomedcentral.com/

Advice for translational neuroscience: move deliberately and build things

https://bioelecmed.biomedcentral.com/

Social frailty and its association with cognitive trajectories in older adults: a prospective cohort study

https://alzres.biomedcentral.com/

Bone disease and oromaxillofacial disorders: a cross- sectional study in a Tanzanian pediatric population

https://ojrd.biomedcentral.com/

Lasting effects of contact lenses that slow myopia in kids

https://www.nih.gov/news-events/nih-research-matters/lasting-effects-contact-lenses-slow-myopia-kids

Potential new target for malaria discovered

https://www.nih.gov/news-events/nih-research-matters/potential-new-target-malaria-discovered

Risk and future burden of dementia in the United States

https://www.nih.gov/news-events/nih-research-matters/risk-future-burden-dementia-united-states

martes, 18 de febrero de 2025

Many Men with Metastatic Prostate Cancer Are Not Getting the Recommended Treatments, Study Finds

https://www.cancer.gov/news-events/cancer-currents-blog/2025/metastatic-prostate-cancer-combination-treatments?cid=eb_govdel

Incidence, case fatality, and functional outcome of intracerebral haemorrhage, according to age, sex, and country income level: a systematic review and meta-analysis

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(24)00349-1/fulltext?dgcid=hubspot_update_feature_updatealerts_lanepe&utm_campaign=update-lanepe&utm_medium=email&_hsenc=p2ANqtz-8kqEDB_qTvnBXBxB-n8uBkQ7pZl-ZjVhuaWwJdvwD134nSgQBZN_kt09qn3LYdA3JURmxHORZLXjViDrjikIgQtKBQew&_hsmi=347695154&utm_content=347674418&utm_source=hs_email

Comparative effectiveness of different therapies for Clostridioides difficile infection in adults: a systematic review and network meta-analysis of randomized controlled trials

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(24)00320-X/fulltext?dgcid=hubspot_update_feature_updatealerts_lanepe&utm_campaign=update-lanepe&utm_medium=email&_hsenc=p2ANqtz-9MBAIu9wkD1HdgaDq1HmdjfpbET00zvUcXcWu7Tf3QjSapnooINXUIzZSST1C32SB0DQo4omxKKjTOHwQbXrRK7UuEHQ&_hsmi=347695154&utm_content=347674418&utm_source=hs_email

Could SSRIs protect against infections? A mouse study has hints

https://www.statnews.com/2025/02/18/health-news-cdc-data-hhs-job-cuts-ssri-research-gender-affirming-executive-order-morning-rounds/

Biogen partners with Stoke Therapeutics on drug for severe epilepsy Stoke’s therapy may become first treatment to target underlying, genetic cause of Dravet syndrome

https://www.statnews.com/2025/02/18/biogen-stoke-therapeutics-dravet-syndrome-zorevunersen/

Duchenne gene therapy from Solid Biosciences produces promising results in early study The company’s shares soared early Tuesday as it released results from three patients

https://www.statnews.com/2025/02/18/solid-duchenne-muscular-dystropthy-gene-therapy-sarepta-elevidys/

What my sister’s life and death taught me about the NIH I don’t recognize the caricature of the NIH that politicians are railing against

https://www.statnews.com/2025/02/18/nih-nci-vhl-genetic-disorder-belzutifan-family/

Is a high protein diet the best and safest way to increase strength? Kamala Thiagarajan | BBC | February 18, 2025

https://geneticliteracyproject.org/2025/02/18/is-a-high-protein-diet-the-best-and-safest-way-to-increase-strength/?mc_cid=761c6bb684&mc_eid=b73600b7ac

Scientists and ethicists raise eugenic concerns about embryonic gene editing even when it could block diseases Peter Visscher et. al | Nature | February 18, 2025

https://geneticliteracyproject.org/2025/02/18/scientists-and-ethicists-raise-eugenic-concerns-about-embryonic-gene-editing-even-when-it-could-block-diseases/?mc_cid=761c6bb684&mc_eid=b73600b7ac

Musk’s brain streaming Neuralink is far from commercialization Antonio Regalado | MIT Technology Review | February 18, 2025

https://geneticliteracyproject.org/2025/02/18/musks-brain-streaming-neuralink-is-far-from-commercialization/?mc_cid=761c6bb684&mc_eid=b73600b7ac

How climate change is altering the look, taste and nutrition content of fruits and vegetables Kenneth Fu Xian Ho, Liudmila Tarabashkina, Rajesh Rajaguru | February 18, 2025

https://geneticliteracyproject.org/2025/02/18/how-climate-change-is-altering-the-look-taste-and-nutrition-content-of-fruits-and-vegetables/?mc_cid=761c6bb684&mc_eid=b73600b7ac

Transforming oncology care in Latin America: artificial intelligence-driven solutions to bridge workforce gaps

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00681-8/abstract?utm_campaign=update-lanonc&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanonc&_hsenc=p2ANqtz--Po6Eq4jpEr9RbWg4ZtHPNNcyTisPcsH5f1miTmXeK_VtyIusJJeLBoqQLCDWcQ1vN3I-dVNHB2CTqTbvdAF3b5q8g5Q&_hsmi=347675666&utm_content=347673518&utm_source=hs_email

Psychosocial impact associated with a multicancer early detection test (PATHFINDER): a prospective, multicentre, cohort study

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00645-4/abstract?utm_campaign=update-lanonc&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanonc&_hsenc=p2ANqtz-99zk2zOQgd75iRdzSzmlmp4nJIlzzW7nGp_5NLlOKfcDJ6gB-hs-4EOVv2AprzHSpX3IqyEfdWCYggQnwpDHfG2P56YQ&_hsmi=347675666&utm_content=347673518&utm_source=hs_email

Fires and their smouldering health effects The Lancet Oncology

https://www.thelancet.com/journals/lanonc/issue/vol26no2/PIIS1470-2045(25)X0002-4

Common Sense Oncology principles for the design, analysis, and reporting of phase 3 randomised clinical trials

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00451-0/abstract?utm_campaign=update-lanonc&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanonc&_hsenc=p2ANqtz-8gZozJJZJq3BktoiaWodCHBOznhz3yZtRfoJsq-w5w7FJL2Ouz6AKBFmFuf5eFglO9yu_6rLwX-iJAOsgEtfp6WXIlug&_hsmi=347675666&utm_content=347673518&utm_source=hs_email

Burden of RSV infections among young children in primary care: a prospective cohort study in five European countries (2021–23)

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00367-9/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz-9TtjA5VLjA_7OznNKuFZtmazSu8izwdUWgVptajkfU-bjQAXsSMgDGEAZJwpr-yqbCbv-zlg_izCziQXzUFdPQC2FZ3g&_hsmi=347684716&utm_content=347674072&utm_source=hs_email

Baseline characteristics of patients in the Chinese Bronchiectasis Registry (BE-China): a multicentre prospective cohort study

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00364-3/fulltext?dgcid=hubspot_update_feature_updatealerts_lanres&utm_campaign=update-lanres&utm_medium=email&_hsenc=p2ANqtz-9x3zK7Z4VGIyWmdgAFJ-3FUj1XpCKCEXny6n0G8Tk_eiHTkJHm1YQYAKPcovZyzwgC5XiEsYyzaRG41Nm4Fi5TYcAdsw&_hsmi=347684716&utm_content=347674072&utm_source=hs_email

Respiratory research funding: consequences of neglect The Lancet Respiratory Medicine

https://www.thelancet.com/journals/lanres/issue/vol13no2/PIIS2213-2600(25)X0002-3

Perioperative tislelizumab plus neoadjuvant chemotherapy for patients with resectable non-small-cell lung cancer (RATIONALE-315): an interim analysis of a randomised clinical trial

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00269-8/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz--Oj5PFObXwhc-OHSgf-Y-x-JM3ievAauw-XcIe2RFg5nslP58Vb7GBvjhziH1YNBQ80cll7cBW9BnJ6m3ey5I1qQD9jw&_hsmi=347684716&utm_content=347674072&utm_source=hs_email

Healthful diet linked to reduced risk of cognitive decline Research HighlightsOctober 18, 2024

https://www.nia.nih.gov/news/healthful-diet-linked-reduced-risk-cognitive-decline?&utm_source=nia-eblast&utm_medium=email&utm_campaign=general-20250218

lunes, 17 de febrero de 2025

Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial ++++++

https://www.thelancet.com/journals/landia/article/PIIS2213-8587(24)00309-7/fulltext?dgcid=hubspot_update_feature_updatealerts_landia&utm_campaign=update-landia&utm_medium=email&_hsenc=p2ANqtz-96DygjA-lykZjE4mGbkQtdGTGYfsBTRqxG5yKLzczDe9NSOO4Rmjh4mbD9GVQohPhaRbe0CWUjVyYMaK78ZvhVDMV5BQ&_hsmi=346816850&utm_content=346774970&utm_source=hs_email Feb 2025 Volume 13Number 2p75-164, e2 Redefining obesity: advancing care for better lives The Lancet Diabetes & Endocrinology https://www.thelancet.com/journals/landia/issue/vol13no2/PIIS2213-8587(25)X0002-4 Definition and diagnostic criteria of clinical obesity https://www.thelancet.com/commissions/clinical-obesity?dgcid=hubspot_update_feature_landiaobesity25&utm_campaign=update-landia&utm_medium=email&_hsenc=p2ANqtz-9KtW9qd3RJCSWJNjgd-KWiEkaNATcOHiOkUptd9-A8I2XvMh71ZLcQIDVLpNU9Zo_WqZPrKXjlrG22fSb551MwW3_XHw&_hsmi=346816850&utm_content=346774970&utm_source=hs_email Diagnosing clinical obesity https://www.thelancet.com/infographics-do/clinical-obesity-25?dgcid=hubspot_update_feature_landiaobesity25&utm_campaign=update-landia&utm_medium=email&_hsenc=p2ANqtz-8nzmEOOSMXFCnOiUuvEbBQqRKwXZvvlrrUO7Sek-JBCTwZwL_iFu1EBKvydKhNzV5hw5obpPvJnYgYlJz8FKIgETTjQA&_hsmi=346816850&utm_content=346774970&utm_source=hs_email Hybrid closed-loop insulin therapy and risk of severe hypoglycaemia and diabetic ketoacidosis in young people (aged 2–20 years) with type 1 diabetes: a population-based study https://www.thelancet.com/journals/landia/article/PIIS2213-8587(24)00284-5/fulltext?dgcid=hubspot_update_feature_updatealerts_landia&utm_campaign=update-landia&utm_medium=email&_hsenc=p2ANqtz-8C-78AZFeMzhNQa8va4x1mV_t2vqEnzboN9EBbfH_zr7a8-7fWdiMC6gXynOLLwCfR4f6vcJ_m61BXXJvnOdp3HByohQ&_hsmi=346816850&utm_content=346774970&utm_source=hs_email Overweight and obesity among Israeli adolescents and the risk for serious morbidity in early young adulthood: a nationwide retrospective cohort study https://www.thelancet.com/journals/landia/article/PIIS2213-8587(24)00287-0/abstract?utm_campaign=update-landia&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_landia&_hsenc=p2ANqtz--Fk_w_EaOe5xm7f9B-0JUTajoS7BZjGBJp6KjSmjaK2SRtItrITyQ2WXg4ceIPL8xwT-aKCwFbCCYHwSUnIhRJWZZtmA&_hsmi=346816850&utm_content=346774970&utm_source=hs_email

Cholangiocarcinoma Day Session Thursday, 20 Feb, 11:00 - 12:30 CEST

https://events-apps.easl.eu/lcs2025/en-GB/pag/session/103602?utm_campaign=conferencealerts&utm_medium=email&_hsenc=p2ANqtz-9KgzR8r4y9WScv7fztOHbA0BJDnLADUWv5xaegj9D9il86qVGK9tmyrUyALYVFbl_ugMNIzWaSdaSaKaOPISrQfihSeQ&_hsmi=346742101&utm_content=346742101&utm_source=hs_email Cholangiocarcinoma day session Thurs, Feb 20, 2025 11:00-12:30 CET

Standardized protocol for labor induction: a type I hybrid effectiveness-implementation trial

https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(24)00283-7/fulltext?dgcid=hubspot_email_infocusalerts-obgyn_feature&utm_campaign=infocusalerts-obgyn&utm_medium=email&_hsenc=p2ANqtz--riujw2uxpItABC3GLqED38XyiAAPWR80-1ewJp3H__34BFDUn3MgPAQ9ZXy1bGyx2h-m6D7EQGikFxTsnx7Cs4sf2Gw&_hsmi=347404617&utm_content=346963605&utm_source=hs_email