CIENCIASMEDICASNEWS: COVID-19 GPH|Home|PHGKB

lunes, 12 de octubre de 2020

COVID-19 GPH|Home|PHGKB

Spotlight

The SARS-CoV-2 effective reproduction rate has a high correlation with a contact index derived from large-scale individual location data using GPS-enabled mobile phones in Germany
S Ruediger et al, MEDRXIV, October 9, 2020

We derived the contact index, an index for the intensity of contact behavior from spatial proximity between individuals as proxy for physical interaction based on large-scale GPS mobile phone data of 1.15 to 1.4 million users A high correlation between the contact index and the effective reproduction number six days later could be observed in three different phases of the virus spread in Germany. Our model can potentially forecast the time evolution of the pandemic in Germany.

Inhibiting Ebola virus and SARS-CoV-2 entry.
Wells Alexandra I et al. Science (New York, N.Y.) 2020 Oct 370(6513) 167-168

Mechanisms by which cells defend against many viruses remain largely unknown. Defining them is important not only for understanding viral pathogenesis but also for informing the development of antiviral therapeutics. Concerted efforts of antiviral factors are central to host cell defense. Without them, the cell remains defenseless against harmful pathogens.

Investigating the Impact of COVID-19 during Pregnancy
CDC, October 9, 2020

Based on what is known at this time, pregnant people might be at an increased risk for severe illness from COVID-19 compared to non-pregnant people. Additionally, pregnant people with COVID-19 might have an increased risk of adverse pregnancy outcomes, such as preterm birth.

Researchers face hurdles to evaluate, synthesize COVID-19 evidence at top speed
J Brainard, Science, October 8, 2020

To avoid out-of-date reviews, several groups have been developing an approach little used before the pandemic: “living reviews” they plan to update as new relevant studies emerge. Each review update, like the original review, requires rigorously searching for relevant papers—and considering whether to rework the conclusions to account for new findings.