09/01/2020 |
NCI-funded studies are testing whether different drug doses and schedules might decrease the likelihood that drug resistance will develop as a result of evolutionary dynamics between cancer cells. In adaptive therapy, drugs are given in a way that allows a proportion of the drug-sensitive cells to disproportionately survive, so that they may compete with and block the growth of the drug-resistant cells. With this approach, it is possible that the tumor may never be completely eradicated, but it may remain relatively stable, thereby limiting the development of uncontrollable drug resistance.
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