CIENCIASMEDICASNEWS: Experience the convenience of pre-made signaling pathway lentiviruses

miércoles, 1 de julio de 2020

Experience the convenience of pre-made signaling pathway lentiviruses

	Cell Biology
	The latest cell & molecular biology news from News Medical

Experience the convenience of pre-made signaling pathway lentiviruses

Ready-to-use, functionally tested reporter lentiviruses for quick, sensitive monitoring of transduction pathway activation. Options to express a luminescence or fluorescent reporter under many pathway specific promoters. Ideal for generating pathway screening assay cell lines for cell based assays in a variety of cell types. Custom-made also available.

Choose your Pathway

Micro-CT: Fancy gadget or indispensable technology towards accurate quantification of lung disease and therapy?

Lung diseases such as fibrosis, viral infection and cancer are life-threatening conditions for which our knowledge on etiology and/or effective treatment options still contains important gaps.

To unravel disease processes and to test novel therapeutic approaches, investigators typically rely on end-stage procedures (such as serum analysis, cyto-/chemokine profiles and selective tissue histology from animal models).

These techniques are useful but provide only a snapshot of disease processes that are essentially dynamic in time and space.

Researchers discover a mechanical cause for cell extrusion

In the human body, the inner or outer boundaries of organs are lined with the supposed epithelial sheets.

	Study demonstrates the role of p53 gene in cell cycle regulation and apoptosis The p53 gene is crucial in cell biology and thus cell replacement therapy. The function of this gene is to control the cell cycle and stop tumor formation.

	Single-cell sequencing can reveal genetic diversity of cancer cells In the past, the potential to sequence the genome of the tumor has redefined the treatment of cancer by detecting cancer drivers at the molecular level.

	Scientists uncover a moving target in small cell lung tumors Lung cancers account for approximately 25 percent of all cancer deaths. Even among those who do not smoke, 1 in 15 men and 1 in 17 women are expected to develop lung cancer in their lifetime, according to the American Cancer Society.

	New study outlines the mechanisms behind cell fusion Scientists have known for a decade that cells that fuse with others to perform their essential functions - such as muscle cells that join together to make fibers - form long projections that invade the territory of their fusion partners.