11/12/2015
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Artistic illustration of density map of the enzyme beta-galactosidase (beta-gal) determined by cryo-electron microscopy at 2.2 angstrom resolution. An essential enzyme in the human body, beta-gal is commonly used in molecular biology as a reporter marker to monitor gene expression. The foreground shows the overall shape of the molecule (right) and an electron beam striking a specimen grid (left), while the background shows images of single molecules (upper left) and the atomic contours of amino acids in the structure (lower right). |
11/12/2015
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2.2 angstrom resolution electron density map of beta-galactosidase (beta-gal) as determined by high-resolution cryo-electron microscopy (cryo-EM). An essential enzyme in the human body, beta-gal is commonly used in molecular biology as a reporter marker to monitor gene expression. The map is colored by protein subunit. As of October 2015 it is the highest resolution structure determined by single-particle cryo-EM to date. |
11/12/2015
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Cryo-electron tomographic image of a virus-like particle displaying Ebola virus surface spikes (top) and visualization of their three-dimensional structure (bottom). |
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