Genomics|Update|Current ► CANCER

Genomics|Update|Current

Cancer

A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival
Shahzia Anjum e al. Genome Medicine, June 27, 2014

Assessing the clinical utility of cancer genomic and proteomic data across tumor types
Yuan Y, et al. Nature Biotechnology (2014) doi:10.1038/nbt.2940 Jun 22

Analysis of TCGA samples finds molecular data adds little predictive power to clinical models, Genome Web, Jun 27 [by free subscription only]

Familial transmission of prostate, breast and colorectal cancer in adoptees is related to cancer in biological but not in adoptive parents: A nationwide family study.
Zöller B, et al. Eur J Cancer. 2014 Jun 18. pii: S0959-8049(14)00717-5.

Family history is 'a bigger risk factor than lifestyle' for some cancers, Medical News Today, Jun 30

Genomic testing in cancer: Patient knowledge, attitudes, and expectations 
Blanchette PS, et al. Cancer 2014 Jun

Interest of UGT1A1 genotyping within digestive cancers treatment by irinotecan 
Boyer JC, et al. Bull Cancer 2014 Jun;101(6):533-53

Mechanisms underlying mutational signatures in human cancers
Helleday T, et al. Nature Reviews Genetics (2014) July 1

Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis.
Weaver JM, et al. Nat Genet. 2014 Jun 22.

Genetic test could 'hugely improve' prognosis for esophageal cancer, Medical News Today, Jul 1

Perceptions of prostate cancer screening controversy and informed decision making: Implications for development of a targeted decision aid for unaffected male first-degree relatives 
Gwede CK, et al. Am J Health Promot 2014 Jun

The correlation of the International Association for the Study of Lung Cancer (IASLC)/American Thoracic Society (ATS)/European Respiratory Society (ERS) classification with prognosis and EGFR mutation in lung adenocarcinoma 
Yanagawa N, et al. Ann Thorac Surg 2014 Jun

A new test to predict breast cancer risk, by Kam Marwaha, Biomed Central Blog, Jun 27