Academia Drug Development and Pharmacotherapy: a new scientific translational journal focused on personalized therapy Federico Pea* [1,2]

Academia.edu is launching a new scientific journal in the field of drug development and pharmacotherapy. This will be a translational journal focused on all the different aspects which, from bench to bedside, may enable maximizing the likelihood of providing more effective and safe pharmacotherapy in the era of precision medicine. Modern pharmacotherapy is increasingly based on well-defined molecular targets, and this may clearly improve effectiveness, especially in some fields such as oncology. However, there is an urgent need to personalize therapy to each individual patient, escaping from the false contention that “one size may fit all” and moving toward tailored therapies based on predictive models. This has been well-defined in the last twenty years or so, especially in the field of antibiotic therapy, in which both underlying diseases and pathophysiology have been shown to deeply alter the pharmacokinetic–pharmacodynamic behavior of drugs with the consequent need of individualized dosing regimens. Indeed, the same is also expected to occur in other therapeutic areas, and just to mention one among many, recent studies suggest that a paradigm shift to personalized dosing regimens might be applied even to the major topic of therapeutic monoclonal antibodies. https://www.academia.edu/academia-drug-development-and-pharmacotherapy/1/1/10.20935/AcadDrug7906