CIENCIASMEDICASNEWS: Medical News | Medical Articles | Antibodies

miércoles, 27 de marzo de 2019

Medical News | Medical Articles | Antibodies - Mar 27, 2019 Edition

	March 27, 2019
	Antibodies
	The latest antibodies news from News Medical

SEC-MALS for absolute biophysical characterization

Molar mass, aggregates, fragments and complexes: SEC-MALS is essential. Characterize the solution properties of biomolecules without reference to standards, conformation or column elution properties.

Monitoring Cancer Treatments with Immuno-PETThe clinical use of full-length mAbs as imaging agents can be challenging, due to their long biological half-life and relatively slow tumor penetration, which may affect tumor-to-background contrast at early time points. In this webinar, Dr Gabriela Kramer-Marek will focus on HER-specific imaging radioconjugates that could provide unique information as cancer biomarkers, including quantification of receptor heterogeneity and early detection of changes in target expression in response to therapy.

IgG antibodies play unexpected role in atherosclerosis

Researchers at Karolinska Institutet in Sweden have found that type IgG antibodies play an unexpected role in atherosclerosis. A study on mice shows that the antibodies stabilize the plaque that accumulates on the artery walls, which reduces the risk of it rupturing and causing a blood clot. It is hoped that the results, which are published in the journal Circulation, will eventually lead to improved therapies.

	Role of immunological imprinting in elicitation of new antibodies We are repeatedly exposed to the influenza virus via infections, vaccinations and our communal environments. The annual flu shot is believed to be the best line of defense, and doctors recommend vaccinations every year because the flu virus is in a constant state of adaptation and mutation, rendering older vaccines obsolete.

	Premature babies also have protective anti-viral antibodies Even premature babies carry anti-viral antibodies transferred from the mother, researchers at Karolinska Institutet in Sweden report in a paper on maternal antibodies in newborns, published in the journal Nature Medicine.

	Blood donors' leftover immune cells provide crucial insights into antibody affinity During some kinds of blood donations, you get most of your blood back. For example, platelet donation involves a procedure in which donor blood is filtered to harvest the platelets for medical use and the rest of the blood components are returned to the donor's body.

	Custom-made proteins could result in antibodies that fight HIV Researchers have developed a new method for the creation of custom-made proteins that can bypass the protective coating of the HIV virus, allowing antibodies to neutralize the Env gene, which enables the virus to bind and enter human immune cells.

	Researchers define pathway that helps us make antibodies Our bodies are continuously concocting specific antibodies to thwart invaders like a virus or even pollen, and scientists have new information about how the essential production gets fired up and keeps up.