Hepatitis
Hepatitis: Pharmacogenomic Insights - July 14, 2015
CDC and Related Info
- Apolipoprotein E and protection against hepatitis E virus infection in American, non-Hispanic blacks.Zhang L et al.Hepatology 2015 Jun 11.
- Hepatitis Awareness Month
- Using advanced molecular techniques for rapid identification of hepatitis C outbreaks
- World Hepatitis Day
- CDC information on viral hepatitis
- Take this 5 minute hepatitis risk assessment
- Recommendations for the identification of chronic hepatitis C virus infection among persons born during 1945–1965
- Genes reported in relation to hepatitis, including genomewide association studies via theHuGE Navigator
Comparative clinical effectiveness and value of novel interferon-free combination therapy for hepatitis C genotype 1: Summary of California Technology Assessment Forum Report
Tice JA et al. JAMA Internal Medicine, July 13, 2015
Tice JA et al. JAMA Internal Medicine, July 13, 2015
Apolipoprotein E and protection against hepatitis E virus infection in American, non-Hispanic blacks.
Zhang L et al. Hepatology 2015 Jun 11.
Zhang L et al. Hepatology 2015 Jun 11.
CDC information: Hepatitis Awareness Month
Interleukin 28B polymorphisms as predictors of sustained virological response in chronic hepatitis C: systematic review and meta-analysis.
Cariani E et al. Pharmacogenomics J. 2015 Apr 28.
Cariani E et al. Pharmacogenomics J. 2015 Apr 28.
Intracellular accumulation of boceprevir according to plasma concentrations and pharmacogenetics.
Cusato J et al. Int. J. Antimicrob. Agents 2015 Mar 14.
Cusato J et al. Int. J. Antimicrob. Agents 2015 Mar 14.
Serum interferon-related microRNAs as biomarkers to predict the response to interferon therapy in chronic hepatitis C genotype 4.
Motawi TK et al. PLoS ONE 2015 (3) e0120794
Motawi TK et al. PLoS ONE 2015 (3) e0120794
PEG-interferon-α ribavirin-induced HCV viral clearance: a pharmacogenetic multicenter Spanish study.
Milara J et al. Farm Hosp 2015 Jan-Feb (1) 29-43
Milara J et al. Farm Hosp 2015 Jan-Feb (1) 29-43
The role of pharmacogenetics in the treatment of chronic hepatitis C infection.
Kawaguchi-Suzuki M et al. Pharmacotherapy 2014 Feb (2) 185-201
Kawaguchi-Suzuki M et al. Pharmacotherapy 2014 Feb (2) 185-201
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for IFNL3 (IL28B) genotype and PEG interferon-α-based regimens.
Muir AJ et al. Clin. Pharmacol. Ther. 2014 Feb (2) 141-6
Muir AJ et al. Clin. Pharmacol. Ther. 2014 Feb (2) 141-6
Hepatitis: Recent Genomic Insights - February 9, 2015
CDC information: Using advanced molecular techniques for rapid identification of hepatitis C outbreaks
CDC paper: Outbreak of hepatitis A in the USA associated with frozen pomegranate arils imported from Turkey: an epidemiological case study
Collier MG, et al. Lancet Infect Dis. 2014 Sep 3. pii: S1473-3099(14)70883-7.
Collier MG, et al. Lancet Infect Dis. 2014 Sep 3. pii: S1473-3099(14)70883-7.
CDC paper: Next-generation sequencing reveals large connected networks of intra-host HCV variants
Campo DS, et al. BMC Genomics. 2014 Jul 14;15 Suppl 5:S4.
Campo DS, et al. BMC Genomics. 2014 Jul 14;15 Suppl 5:S4.
Ultradeep pyrosequencing of NS3 to predict response to triple therapy with protease inhibitors in previously treated chronic hepatitis C patients.
Larrat S et al. J Clin Microbiol. 2015 Feb;53(2):389-97.
Larrat S et al. J Clin Microbiol. 2015 Feb;53(2):389-97.
Differentiation of acute from chronic hepatitis C virus infection by NS5B deep sequencing: A population-level tool for incidence estimation.
Montoya V et al. Hepatology. 2015 Feb 2.
Montoya V et al. Hepatology. 2015 Feb 2.
Whole genome characterization of hepatitis B virus quasispecies with massively parallel pyrosequencing.
Li F, et al. Clin Microbiol Infect. 2014 Oct 29
Li F, et al. Clin Microbiol Infect. 2014 Oct 29
Age-related immune clearance of hepatitis B virus infection requires the establishment of gut microbiota.
Chou HH, et al. Proc Natl Acad Sci U S A. 2015 Feb 2
Chou HH, et al. Proc Natl Acad Sci U S A. 2015 Feb 2
Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity.
Fujimoto A, et al. Nat Commun. 2015 Jan 30;6:6120
Fujimoto A, et al. Nat Commun. 2015 Jan 30;6:6120
A deep-sequencing method detects drug-resistant mutations in the hepatitis B virus in Indonesians.
Widasari DI, et al. Intervirology. 2014;57(6):384-92.
Widasari DI, et al. Intervirology. 2014;57(6):384-92.
Cost-effectiveness of IL28Β genotype-guided protease inhibitor triple therapy versus standard of care treatment in patients with hepatitis C genotypes 2 or 3 infection.
Bock JA, et al. Public Health Genomics. 2014;17(5-6):306-19.
Bock JA, et al. Public Health Genomics. 2014;17(5-6):306-19.
A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration.
King LY, et al. Gut. 2014 Aug 20.
King LY, et al. Gut. 2014 Aug 20.
Hepatitis C virus in the new era: perspectives in epidemiology, prevention, diagnostics and predictors of response to therapy.
Ansaldi F, et al. World J Gastroenterol. 2014 Aug 7;20(29):9633-52.
Ansaldi F, et al. World J Gastroenterol. 2014 Aug 7;20(29):9633-52.
Deep sequencing: becoming a critical tool in clinical virology.
Quiñones-Mateu ME, et al. J Clin Virol. 2014 Sep;61(1):9-19
Quiñones-Mateu ME, et al. J Clin Virol. 2014 Sep;61(1):9-19
Hepatitis: Genomics & Public Health - July 31, 2014
CDC information: World Hepatitis Day
CDC information on hepatitis
Hepatitis B and Hepatitis C can become chronic, life-long infections which can lead to liver cancer. Millions of Americans are living with chronic viral hepatitis, and many do not know they are infected
CDC information on hepatitis
Hepatitis B and Hepatitis C can become chronic, life-long infections which can lead to liver cancer. Millions of Americans are living with chronic viral hepatitis, and many do not know they are infected
Take this 5 minute hepatitis risk assessment developed by the CDC and get a personalized report
CDC paper: Viral hepatitis C gets personal--the value of human genomics to public health.
Zhang L, Gwinn M, Hu DJ. Public Health Genomics. 2013;16(4):192-7.
Zhang L, Gwinn M, Hu DJ. Public Health Genomics. 2013;16(4):192-7.
Did you know? > 1300 genes have been reported in relation to risk and outcomes of hepatitis, including 56 genomewide association studies and 70 meta analyses? To find out more, visit the HuGE Navigator
Integrative functional genomics of hepatitis C virus infection identifies host dependencies in complete viral replication cycle
Qisheng Li et al. PloS Pathogens, May, 2014
Qisheng Li et al. PloS Pathogens, May, 2014
Meta-analysis: implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C
María A Jiménez-Sousa et al. BMC Medicine 2013
María A Jiménez-Sousa et al. BMC Medicine 2013
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