Current Highlight from October 5, 2014
International Conference on Neuroprotective Agents
NCTR scientists presented their preclinical research results at the 12th International Conference on Neuroprotective Agents held September 28-October 1, 2014, in Charlottesville, VA. The topics of presentations involved issues ranging from penetration of the blood-brain barrier by therapeutics to the reversible/irreversible effects of anesthetics on neural cells. The specific topics for the presentations were:
- Mediation of tight junctions in the blood-brain barrier by A25-35-RAGE
- Neuroprotective role of the TRPC6 receptor in a mouse model of Parkinson’s disease
- Protective effects of N-acetylcysteine against nanoparticle-induced cytotoxicity in an in vitro blood-brain barrier model
- Mobilization of neural stem cells after developmental estrogen treatment
- Potential use of leukemia drugs for neuroprotection in Parkinson’s disease
- Effects of silver nanoparticles on human and rat embryonic neural stem cells
- Long-lasting cognitive deficits in nonhuman primates after general anesthesia administered during the first week post-partum
- Neuroprotective effects of acetyl-L-carnitine in a mouse model of Parkinson’s disease
- Use of small-animal PET to monitor sevoflurane-induced neuronal injury in neonatal nonhuman primates
- Effects of propofol on neural stem cells in culture.
For additional information, please contact Merle Paule, Ph.D., Director of Neurotoxicology, FDA/NCTR.
NCTR Research Highlights Archives
- 2014-NCTR Research Highlights
- 2013-NCTR Research Highlights [ARCHIVED]
- 2012-NCTR Research Highlights [ARCHIVED]
- 2011-NCTR Research Highlights [ARCHIVED]
- 2010-NCTR Research Highlights [ARCHIVED]
- 2009-NCTR Research Highlights
- 2008-NCTR Research Highlights [ARCHIVED]
- 2007-NCTR Research Highlights [ARCHIVED]
- 2006-NCTR Research Highlights [ARCHIVED]
Contact FDA
870-543-7000
National Center for Toxicological Research
Food and Drug Administration
3900 NCTR Road
Jefferson, AR 72079
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