Human Granulocytic Anaplasmosis, South Korea, 2013 - Volume 20, Number 10—October 2014 - Emerging Infectious Disease journal - CDC
Volume 20, Number 10—October 2014
Human Granulocytic Anaplasmosis, South Korea, 2013
Anaplasma phagocytophilum, the causative agent of human granulocytic anaplasmosis (HGA), is a zoonotic tickborne pathogen transmitted by ixodid ticks that infects wild and domestic mammals and humans (1–3). HGA was first identified in the United States in 1994 (1) and subsequently in countries in Europe (3), China (4), and Japan (5).
To our knowledge, there is no report regarding the clinical description of HGA patients in South Korea. However,A. phagocytophilum has been detected in Haemaphysalis longicornis, Ixodes nipponensis, and I. persulcatus ticks (6,7) in this country. Molecular epidemiologic studies detected A. phagocytophilum in 2.6% (5/196) of striped field mice (7,8) and in 63.6% (42/66) of Korean water deer (9). Seroprevalence studies showed that 1.8% of serum samples from patients with acute fever were positive for A. phagocytophilum by an immunofluorescence antibody test (10). We report a patient with HGA and characterized the A. phagocytophilum isolate from this patient.
Dr Kye-Hyung Kim is an infectious disease physician and a senior researcher at Seoul National University College of Medicine, Seoul, South Korea. Her primary research interests are medical virology and emerging infectious diseases.
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Suggested citation for this article: Kim KH, Yi J, Oh WS, Kim NH, Choi SJ, Choe PG, et al. Human granulocytic anaplasmosis, South Korea, 2013. Emerg Infect Dis [Internet]. 2014 Oct [date cited]. http://dx.doi.org/10.3201/eid2010.131680
1These authors contributed equally to this article.