lunes, 4 de agosto de 2014

Anticipated Motivation for Genetic Te... [Public Health Genomics. 2014] - PubMed - NCBI

Anticipated Motivation for Genetic Te... [Public Health Genomics. 2014] - PubMed - NCBI

 2014 Jul 19. [Epub ahead of print]

Anticipated Motivation for Genetic Testing among Smokers, Nonsmokers, and Former Smokers: An Exploratory Qualitative Study of Decision Making.


Objectives: This qualitative study explores the public's interest in genetic testing related to cigarette smoking, comparing the public's motivations with researchers' intentions for this technology. Methods: Adult nonsmokers (n = 463), former smokers (n = 163), and current smokers (n = 129) completed an online survey. Within a hypothetical scenario, respondents decided whether they desired genetic testing related to smoking and explained their decision making. A non-parametric Kruskal-Wallis test was used to compare the interest in genetic testing by smoking history group. Inductive content analysis was used to investigate respondents' explanations for their testing decisions. Results: Most nonsmokers (64%) and former smokers (58%) did not want genetic testing. While most current daily smokers were interested in testing (56%), most current occasional smokers were not (52%). Respondents' decision-making explanations were categorized into 3 major themes: Causality, Relevancy and Utility (e.g. personal benefits or harms). The use of causality, relevancy and utility explanations varied by smoking history. Notable perceived benefits of testing included recreation and altruism. Notable perceived harms included fear of fatalistic thoughts and concern about genetic discrimination. Conclusions: Interest in genetic testing was highest among current daily smokers, despite potential utility in other groups. Although respondents' motivations for testing paralleled researchers' intentions of tailoring smoking cessation therapies and increasing motivation to quit or abstain, respondents also raised alternative motivations and fears that healthcare providers would need to address. © 2014 S. Karger AG, Basel.

[PubMed - as supplied by publisher]

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