Flu Clinical Studies: enrolling people who have been diagnosed with the flu or have a history of flu-like illness

NIAID Enrolling Volunteers for Influenza (Flu) Research Studies

NIAID is enrolling people who have been diagnosed with the flu or have a history of flu-like illness to volunteer to participate in clinical research studies. These studies will help scientists investigate new treatment options for people who are at high risk of severe influenza.

Read about NIAID flu studies that are enrolling volunteers
Flu Clinical Studies

For questions about participating in this clinical study, contact:
Patient Recruitment and Public Liaison Office
Toll Free: 1-800-411-1222 TTY: 1-866-411-1010
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NIAID Influenza Clinical Research Studies
You can join the fight against influenza (flu) by volunteering to participate in a clinical study. There is no charge for study-related medical care, including study visits, medications, treatments, and procedures. Volunteers may be compensated for time and travel.

The following are selected studies being conducted at the NIH Clinical Center in Bethesda, MD. The links lead to full study titles and descriptions.

Combination Therapy Study (NCT01227967)
Comparing the Efficacy, Safety, and Tolerability of Combination Antivirals (Amantadine, Ribavirin, Oseltamivir) Versus Oseltamivir for the Treatment of Influenza in Adults at Risk for Complications - Full Text View - ClinicalTrials.gov
This study is enrolling people 18 years of age and older who are at risk of getting severe flu. The purpose of this study is to evaluate if combination therapy will help symptoms resolve faster and with fewer complications.



H1N1 Plasma Therapy Study (NCT01052480)
Safety and Efficacy of Investigational Immune Plasma in Treating Influenza A H1N1 2009 - Full Text View - ClinicalTrials.gov
This study is enrolling people of any age who have been hospitalized with influenza A and are at risk for severe disease. The purpose of this study is to assess the safety, effectiveness, and lab results of H1N1 plasma in people with influenza A.



Influenza in People With Normal or Weakened Immune Systems (NCT00533182)

Influenza in People With Normal and Weakened Immune Systems - Full Text View - ClinicalTrials.gov
This study is enrolling people 3 years of age and older who were clinically diagnosed with the flu within the past 2 months and are able to safely undergo blood draws and nasal washes. The purpose of this study is to evaluate how the immune system responds to influenza infection and compare how the infection differs in patients with a weakened immune system versus those with a healthy immune system.



Viral Infections in Non-immunocompromised Patients (NCT01011712)
The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise - Full Text View - ClinicalTrials.gov
This study is enrolling people of any age who are thought to have normal immune systems, but who have been diagnosed with a viral infection that is unusually severe, prolonged, or persistent. This study will evaluate the participants’ immune systems to determine why the infection developed.