Granulomatosis with polyangiitis (GPA), previously called Wegener’s granulomatosis, is a rare disease in which blood vessels and other tissues become inflamed. This inflammation limits blood flow to important organs in the body, potentially leading to long-term damage. Disease onset and severity varies between patients, and earlier diagnosis and treatment can prevent life-threatening organ failure.
Although the disease can involve any organ system, GPA mainly affects the respiratory tract (sinuses, nose, trachea [windpipe], and lungs) and kidneys. This disorder can affect people at any age and strikes men and women equally. Compared to other racial groups, Caucasians are more commonly affected.
Although the disease can involve any organ system, GPA mainly affects the respiratory tract (sinuses, nose, trachea [windpipe], and lungs) and kidneys. This disorder can affect people at any age and strikes men and women equally. Compared to other racial groups, Caucasians are more commonly affected.
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