Childhood Salivary Gland Tumors Treatment (PDQ®)–Health Professional Version

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Changes to This Summary (08/28/2018)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

This summary was comprehensively reviewed.

Histology and Molecular Features

This section was extensively revised.

Treatment of Childhood Salivary Gland Tumors

Revised text to state that radical surgical removal is the treatment of choice for salivary gland tumors whenever possible, with additional use of radiation therapy for high-grade tumors or tumors that have invasive characteristics such as lymph node metastasis, positive surgical margins, extracapsular extension, or perineural extension (cited Morse et al. as reference 3). Also added text to state that parotid gland tumors are removed with the aid of neurological monitoring to prevent damage to the facial nerve.

Sialoblastoma

Revised text to state that sialoblastoma is a usually benign tumor presenting in the neonatal period, but has been reported to present as late as age 15 years (cited Irace et al. as reference 1). Also added text to state that sialoblastoma rarely metastasizes to the lungs, lymph nodes, or bones.

This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.

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