CHEST: Study shows possible diagnostic biomarker that may detect lung cancer

CHEST: Study shows possible diagnostic biomarker that may detect lung cancer

CHEST: Study shows possible diagnostic biomarker that may detect lung cancer

• RSi Communications
• 31/10/14

as presented at CHEST, the annual meeting of the American College of Chest Physicians

A new study shows that patients with stage I to stage III non-small cell lung cancer (NSCLC) have different metabolite profiles in their blood than those of patients who are at risk but do not have lung cancer. The study was presented at CHEST, held in October in Austin, Texas.

Researchers at the Cleveland Clinic in Cleveland studied the blood serum of 284 subjects, 48% of whom were female with a mean age of 68 years. The subjects were diagnosed with adenocarcinoma or squamous lung cancer: 44% of those at stage I, 17% at stage II, and 39% at stage III. A control group of 194 patient who matched the cancer patients in age, gender, smoking history, COPD, diabetes, and blood lipids were at risk for lung cancer but did not have the disease. There were 534 metabolites identified, 149 of which differed significantly between the cancer and control groups. 

“Our study results showed that patients with lung cancer have altered metabolic processes,” said Peter J. Mazzone, MD, FCCP, Director of the Lung Cancer Program for the Respiratory Institute at Cleveland Clinic. “This information could lead to the development of a diagnostic biomarker for early detection of lung cancer.”

....

Artículos relacionados

• CHEST: Large-scale study shows dramatic decline in mortality rates for ARDS
• CHEST: Using extracorporeal membrane oxygenation during CPR improves outcomes
• CHEST: Study shows CPAP use for sleep apnea does not negatively impact sexual quality of life
• CHEST: Should home oxygen be prescribed for patients who smoke?
• CHEST: Transthoracic ultrasound more effective diagnostic tool than chest radiography in critically Ill patients
• ACCP: Bronchoscopy can be avoided in patients with plain tree-in-bud appearance on CT
• CHEST: Risk factors for obesity-hypoventilation syndrome may also be present in patients at risk for obstructive sleep apnea

....

Más recientes

• CHEST: Should home oxygen be prescribed for patients who smoke?

  03/11/14
• WSC: Researchers test year-long program of home-based stroke care and education

  31/10/14
• WSC: Occupational therapy task-oriented approach in upper extremity post-stroke rehabilitation

  30/10/14
• EUSEM: Twitter ‘a unique information source during disasters’

  06/10/14
• EASD: 'Vintage' vegetables improve the health status of patients with type 2 diabetes when compared to equivalent modern vegetables

  30/09/14

....

Mas Reportes de Congresos

• WSC: Three-year data for decompressive surgery for malignant middle cerebral artery infarct shows lasting benefit • ACEP: Trauma patients with high-risk drinking more likely to return to ED and have a trauma-related admission • ACEP: Emergency physician-placed transvenous pacemakers have a high rate of successful capture • ASTMH: Louisiana health officials tell physicians who have recently travelled to West Africa not to attend ASTMH • CHEST: Should home oxygen be prescribed for patients who smoke? • CHEST: Transthoracic ultrasound more effective diagnostic tool than chest radiography in critically Ill patients • WSC: Seasonal differences and circadian variation in stroke subtypes and occurrence • CHEST: Risk factors for obesity-hypoventilation syndrome may also be present in patients at risk for obstructive sleep apnea • CHEST: Large-scale study shows dramatic decline in mortality rates for ARDS