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National Institutes of Health
Pulmonary Fibrosis
Also called: Idiopathic pulmonary fibrosis, IPF
Pulmonary fibrosis is a condition in which the tissue deep in your lungs becomes scarred over time. This tissue gets thick and stiff. That makes it hard for you to catch your breath, and your blood may not get enough oxygen.
Causes of pulmonary fibrosis include environmental pollutants, some medicines, some connective tissue diseases, and interstitial lung disease. Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. In most cases, the cause cannot be found. This is called idiopathic pulmonary fibrosis.
Symptoms include
- Shortness of breath
- A dry, hacking cough that doesn't get better
- Fatigue
- Weight loss for no known reason
- Aching muscles and joints
- Clubbing, which is the widening and rounding of the tips of the fingers or toes
Your doctor may use your medical history, imaging tests, a biopsy, and lung function tests to diagnose pulmonary fibrosis. There is no cure. Treatments can help with symptoms and improve your quality of life. They include medicines, oxygen therapy, pulmonary rehabilitation, or a lung transplant.
NIH: National Heart, Lung, and Blood Institute
MEDICAL ENCYCLOPEDIA
National Institutes of Health
- The primary NIH organization for research on Pulmonary Fibrosis is the National Heart, Lung, and Blood Institute
Start Here
- Idiopathic Pulmonary Fibrosis(National Heart, Lung, and Blood Institute)
- Understanding Pulmonary Fibrosis(American Lung Association)
Overviews
- Defining Pulmonary Fibrosis(Pulmonary Fibrosis Foundation)
- Frequently Asked Questions about IPF(Coalition for Pulmonary Fibrosis)
- Also available in Spanish
- Idiopathic Pulmonary Fibrosis (IPF)(American Thoracic Society) - PDF
- Pulmonary Fibrosis(Mayo Foundation for Medical Education and Research)
Latest News
- Scientists Spot New Clues to a Deadly Lung Disease(06/11/2014, HealthDay)
- 2 Drugs Offer Hope for Fatal Lung Disease(05/19/2014, HealthDay)
Diagnosis/Symptoms
- Blood Gases Test(American Association for Clinical Chemistry)
- Bronchoscopy(National Heart, Lung, and Blood Institute)
- Bronchoscopy(Patient Education Institute)
- Also available in Spanish
- Chest X Ray(National Heart, Lung, and Blood Institute)
- How Is Idiopathic Pulmonary Fibrosis Diagnosed?(National Heart, Lung, and Blood Institute)
- Spirometry(Mayo Foundation for Medical Education and Research)
- Video-Assisted Thoracic Surgery (VATS)(Harvard Medical School)
- What Are Lung Function Tests?(National Heart, Lung, and Blood Institute)
- What Are the Signs and Symptoms of Idiopathic Pulmonary Fibrosis?(National Heart, Lung, and Blood Institute)
Treatment
- How Is Idiopathic Pulmonary Fibrosis Treated?(National Heart, Lung, and Blood Institute)
- Treatments(Pulmonary Fibrosis Foundation)
- What to Expect When Considering a Transplant(Pulmonary Fibrosis Foundation)
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Rehabilitation/Recovery
- MedlinePlus: Pulmonary Rehabilitation(National Library of Medicine)
- Also available in Spanish
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Disease Management
- Lifestyle Changes(Pulmonary Fibrosis Foundation)
- Living with Idiopathic Pulmonary Fibrosis(National Heart, Lung, and Blood Institute)
- Living with Pulmonary Fibrosis(American Lung Association)
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Specific Conditions
- About Familial Pulmonary Fibrosis(National Jewish Health)
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Related Issues
- Causes of Pulmonary Fibrosis(National Jewish Health)
- Forms of Pulmonary Fibrosis(National Jewish Health)
- What Is Hermansky-Pudlak Syndrome?(American Thoracic Society) - PDF
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Tutorials
- Bronchoscopy(Patient Education Institute)
- Also available in Spanish
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Anatomy/Physiology
- What Are the Lungs?(National Heart, Lung, and Blood Institute)
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Clinical Trials
- ClinicalTrials.gov: Pulmonary Fibrosis(National Institutes of Health)
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Genetics
- Genetics Home Reference: Hermansky-Pudlak syndrome(National Library of Medicine)
- Genetics Home Reference: Idiopathic pulmonary fibrosis(National Library of Medicine)
- Genetics of Familial Pulmonary Fibrosis(National Jewish Health)
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Research
- IPF Research(Coalition for Pulmonary Fibrosis)
- Treatment of Idiopathic Pulmonary Fibrosis with Ambrisentan(American College of Physicians) - PDF
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Journal Articles
References and abstracts from MEDLINE/PubMed (National Library of Medicine)Dictionaries/Glossaries
- Glossary(Coalition for Pulmonary Fibrosis)
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Directories
- Support Groups(Coalition for Pulmonary Fibrosis)
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Organizations
Statistics
- Facts about Idiopathic Pulmonary Fibrosis(Coalition for Pulmonary Fibrosis)
- Prevalence and Incidence(Pulmonary Fibrosis Foundation)
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Patient Handouts
- Blood gases
- Also available in Spanish
- Bronchoscopy
- Also available in Spanish
- Chest x-ray
- Also available in Spanish
- Diffuse interstitial lung disease
- Also available in Spanish
- Idiopathic pulmonary fibrosis
- Also available in Spanish
- Lung diffusion testing
- Also available in Spanish
- Pulmonary function tests
- Also available in Spanish
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