Genomic medicine and the NHS: it is possible

An independent advisory group has urged the UK Government to integrate genomic medicine into the National Health Service (NHS). The Human Genomics Strategy Group (HGSG), established in 2010 after a House of Lords inquiry into genomic medicine, set out their recommendations in a report published on Jan 25. First, the group proposed that the government outline a policy for expansion of genomic technology in the NHS; HGSG emphasised that commissioning of cost-effectiveness studies will be a necessary step. Second, a central national database should be established for genomic data. A major role of this repository will be to aid ongoing research.

HGSG suggest that commissioning of genomic services be undertaken by a national specialised service, with the NHS Commissioning Board taking a lead role. This body would work with the National Institute for Health and Clinical Excellence and the UK Genetic Testing Network to assess the clinical validity of genetic tests and to set quality standards, and collaborate with the Department of Health to establish a service delivery model. HGSG emphasised that changes to education of health professionals should begin urgently so that skilled workers are in place to implement service developments. Public engagement will be essential—the group recommended a campaign to raise awareness about ethical, legal, and social issues relating to genomic technology.

The advisory group noted that the UK must act quickly to avoid being left behind in this field—a point illustrated by the recent launch of the Norwegian Cancer Genomics Consortium, a national collaboration for genome-based diagnostics in cancer treatment. Responding to the report, Health Secretary Andrew Lansley announced plans for a new commissioning and funding structure for molecular testing in UK cancer care, to be complete by April, 2013. This is welcome news in the build up to Feb 4's World Cancer Day, for which this year's theme is “Together it is possible”. This mantra might well be applied to the HGSG's recommendations. Large-scale adoption of genomic technology could revolutionise the health service—achieving it will require collaboration across many key groups, from policy makers to researchers, industry, and health-care workers.