lunes, 31 de octubre de 2016

NHLBI Funding & Research Opportunities and Announcements for October 28, 2016

Funding and Research Opportunities

The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:

Notices:

Reports on Site Visits to the National Primate Research Centers and the
Federally Supported Chimpanzee Sanctuary
(NOT-OD-17-010) National Institutes of Health

Notice Announcing NIDDK-specific Policies Related to New Salary and Research
Cost Allowances for K08 and K23 Career Development Awards
(NOT-DK-17-001)
National Institute of Diabetes and Digestive and Kidney Diseases

Notice of Change in Application Due Date and Other Attachments for RFA-HL-
17-009 Clinical Centers for the NHLBIs Precision Interventions for Severe and/or
Exacerbation Prone Asthma (PrecISE) Network (UG1)
(NOT-HL-16-459)
National Heart, Lung, and Blood Institute

Requests for Applications:

Circadian Mechanisms Contributing to Obesity, Diabetes Metabolism, and
Underlying Heart, Lung, and Blood Disorders (R01)
(RFA-HL-17-020)
National Heart, Lung, and Blood Institute

Your monthly update of news from BioMed Central

BioMed Central Update

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Things of note

Open Access Week 2016: Open in action

The 9^th International Open Access Week has been taking place this month, from 24^th to 30^thOctober. This year’s theme has been “Open in Action” and BioMed Central planned a range of activities to demonstrate how we help Open Access come to life and the steps we are taking to ensure that science and research become more openly available. Do watch our blogs and social media spaces for updates from the event.

Biology Week

This year’s promotion of Biology Week 2016, which was on from 8^th to 16^th October, took us on a fascinating and thought-provoking journey into critical advances in biological research.

Each of our five daily topics – one for every working day – had the power to change life as we know it and more quickly than we ever imaged. Our daily celebrations featured our most highly-accessed articles and blogs, plus Q&As with leading experts, quizzes to test your knowledge and engaging discussions that illuminated the many ways our research impacts the world around us.

You can find out more about Day 1: Bioengineering – Changing our biology here.

Scientific poetry at #SpotOn16 – submit your poems now!

SpotOn London 2016, which will be dedicated to discussing the future of peer review, takes place on 5th November. The community-led conference will cover topics including pre-prints and peer review, automated peer review and how we train peer reviewers. To mark the event, we are hosting a science poetry competition with the opportunity for you to win a cash prize - and submissions are now being accepted. Our Community Manager, Davy Falkner, tells you all about it in his blog. And if you haven’t registered for SpotOn yet, do it now – places for this FREEevent are limited!

New York editors’ conference

In September, we held our first New York Editors’ conference which brought together BioMed Central and SpringerOpen Editors. These days are valued both by the Editors and members of staff for helping us to work together to improve the experience of our authors. The conference ensures that Editors are up-to-date with regards to research integrity and publishing ethics and hear about the latest innovations happening at BioMed Central and SpringerOpen, particularly around peer review. For more information, please visit our blog.

SCOAP³ extended to 2019

SCOAP³, the Sponsoring Consortium for Open Access Publishing in Particle Physics, is a pioneering partnership of 3,000 libraries, funding agencies and research centers in 44 countries, as well as three intergovernmental organizations, working to enable open access in high-energy physics. Founded in 2014, SCOAP³ has just been extended for another three years to December 2019, continuing its support of open access publication of high-energy physics articles, including in two journals from our parent company Springer Nature. Read more about it in our blog.

2016 Nobel Prizes

The 2016 Nobel Prizes were awarded during the first and second week of October and many of this year’s laureates have published with our parent company Springer Nature. Nobel Prize in Physiology or Medicine laureate Yoshinori Ohsumi has published articles in Nature, Nature Cell Biologyand Nature Communications, two of which are highlighted in the Nobel Prize announcement. Previous BioMed Central Nobel laureates include Dr Sydney Brenner who recently co-authored a study on the genome of the ocean sunfish (Mola mola) which was published in GigaScience.

Steven Inchcoombe, Chief Publishing Officer for Springer Nature, said: “Yet again, many of the new Nobel Laureates have trusted Springer Nature to publish their work, and we offer our congratulations to all this year’s winners. It’s a real testament to the quality of our books and journals, that they are seen as a key forum to share knowledge for the world’s most renowned academics.”

BioMed Central in the news

Your judgement of how drunk you are appears to depend on those around you

When drunk and surrounded by other drinkers, people’s judgements of their own levels of intoxication and the associated risks are related to the drunkenness of their peers, not on the objective amount of alcohol they have actually consumed. The research published in BMC Public Health was popular with the world press, gaining 417 media hits.

In the UK, it was covered by outlets including The Guardian, Daily Mailand iNews. It was most widely syndicated in the US, and covered by major international outlets including Scientific American, Science and The Huffington Post. Other coverage includes Le Figaro in France; SPIEGEL Online and Süddeutsche Zeitung in Germany; The Times of India; ABC.es in Spain; and The Australian and Scimex in Australia.

Mediterranean diet could lower the risk of cardiovascular disease in the UK

Research published in BMC Medicine found that Britons eating a Mediterranean diet could lower their risk of developing cardiovascular disease including conditions such as heart attack and stroke. In this study, the first of its kind carried out in a UK population, the researchers found that healthy individuals with greater adherence to a Mediterranean-type diet had 6 to 16% lower risk of future cardiovascular disease compared to individuals who had poor adherence.

This was particularly popular with the mainstream press and specialist outlets in the UK, gaining coverage in BMJ, Medical News Today, Telegraph, Daily Mail, and The Independent. It was reported internationally in palo.gr in Greece; Europa Press, Times of Malta and Heraldo.es in Spain; zazoom.it and quotidiano.net in Italy; The Courier Mail and The Australian in Australia; and Health Medicine Network in US.

Genome of the world’s largest bony fish may explain fast growth rate and large size

The genome of the ocean sunfish (Mola mola), the world’s largest bony fish, was sequenced for the first time by researchers from China National Genebank at BGI-Shenzhen and A*STAR, Singapore. The researchers, who include Nobel Laureate Sydney Brenner, published their results in GigaScience and revealed several altered genes that may explain the fast growth rate and large size of the fish as well as its unusual endoskeleton.

The research was covered in GenomeWeb, and Earth Times in the UK. It was also syndicated in China, by outlets including cnr.cn, ebiotrade, mt.sohu.com, news.xinmin.cn and china.huanqiu.com, and reported in fis.com in Japan; Bild der Wissenschaft in Germany and Asian Scientist in Singapore.

The Future of Epigenetic Drugs

The most popular blog across the BMC Blog Network in August was posted in ‘On Biology’. In it, Sarah Dowie, Journal Development Editor at BioMed Central, sheds some light on the current status and possible future of epigenetic drugs, an incredibly potent class of drugs that could help reverse abnormal gene expression.

Interesting supplements

BMC Public Health

published a meeting report from The Global Influenza Hospital Surveillance Network (GIHSN) Annual Meeting 2015

Proceedings

BMC Genomics and BMC Systems Biology

published selected articles from the International Conference on Intelligent Biology and Medicine (ICIBM) 2015

Proceedings

BMC Genomics and BMC Bioinformatics

published selected articles from the 11th International Symposium on Bioinformatics Research and Applications (ISBRA) 2015

BMC Health Services Research

published articles on Economic and institutional perspectives on health promotion activities for older persons

BMC Public Health

published an article titled Countdown to 2015 country case studies: analysing progress towards maternal and child survival in the Millennium Development Goal era

BMC Bioinformatics

published selected articles from 11th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB) 2014

BioMed Central on the road

American Public Health Association (APHA)

Denver, USA, 29/10/2016

BGI annual conference

Shenzhen, China, 04/11/2016

American Society of Tropical Medicine and Hygiene 65^thAnnual Meeting

Atlanta, USA, 13/11/2016

9^th European Public Health Conference

Vienna, Austria, 09/11/2016

Society for Immunotherapy of Cancer 31st Annual Meeting

National Harbor, Maryland, 9/11/2016

SfN 46^th annual meeting

San Diego, USA, 12/11/2016

Fourth Global Symposium on Health Systems Global

Vancouver, Canada, 14/11/2016

Best wishes,

The BMC Update Team

For further information or enquiries please contact Customer Services at:info@biomedcentral.com.

BioMed Central Ltd

236 Gray's Inn Road, London, WC1X 8HB,

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NCI at APHA 2016 - October 31, 2016

NCI at APHA 2016 - October 31, 2016

APHA 2016 banner

NCI at APHA 2016 Highlights

From the National Cancer Institute

Please note that all times listed are in local Chicago time (CDT)

Today at APHA

Sessions Featuring NCI Staff:

Ensuring Access to Cancer Screening: Barriers, Benefits, and Barbershops
10:50 AM - 11:10 AM
Urban/Rural Disparities in Ecological Cancer Screening and Mortality Rates: Socioeconomic and Healthcare Explanations

NCI Presenter: Jennifer Moss, NCI, Division of Cancer Control and Population Sciences

Poster Sessions Featuring NCI Staff:

International Health Poster Session 5 - Maternal and Child Health
10:30 AM - 11:30 AM
Impact of Secondhand Smoke on Pregnancy Outcomes: A Meta-Analysis of International Studies

NCI Presenter: Amanda Huffman, NCI, Division of Cancer Control and Population Sciences

Special Topics in Cancer Research: HPV Vaccination and Clinical Trial Participation
12:30 PM - 1:30 PM
Communicating about Clinical Trials in the Digital Age to Increase Awareness and Educate

NCI Presenter: Meghan Byrne, NCI, Office of Communications and Public Liaison

Stop by NCI Exhibit Booth (#515)

Meet the experts below, order free publications, and learn about NCI programs and initiatives at interactive kiosks.

Meet the Experts:

10:30 AM

Ashleigh LoVette
The NCI Health Communications Internship Program: An interactive session with a former intern

1:00 PM

Angela Falisi
HINTS: The Health Information National Trends Survey

1:30 PM

David Nelson
The National Cancer Institute's Cancer Prevention Fellowship Program

2:00 PM

Meghan Byrne
Cancer Communications Tailored to the Latino Population

2:30 PM

Precilla Belin & Emmanuel Taylor
Overview of NCI-funded Cancer Health Disparities Research, Training, and Outreach Programs

3:00 PM

Sylvia Chou
New Directions of Cancer Communication Research

3:30 PM

Antoinette Percy-Laurry
Cancer Control P.L.A.N.E.T: Plan, Link, Act, Network with Evidence-based Tools

Primary CNS Lymphoma Treatment (PDQ®)—Health Professional Version - National Cancer Institute

Primary CNS Lymphoma Treatment (PDQ®)–Health Professional Version

LYMPHOMA

SECTIONS

Changes to This Summary (10/28/2016)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Treatment Option Overview for Primary CNS Lymphoma

Added Ferreri et al. as reference 34.

Added text to state that in a phase II study of 32 patients, induction chemotherapy with rituximab plus methotrexate plus procarbazine plus vincristine was consolidated with high-dose chemotherapy with thiotepa, cyclophosphamide, and busulfan, followed by autologous stem cell transplant (ASCT) and no whole-brain radiation therapy (WBRT). Also added statistics for median follow-up (cited Omuro et al. as reference 36 and level of evidence 3iiiDiv).

Added text to state that several prospective randomized trials are comparing the value of WBRT and the value of ASCT as consolidation after high-dose methotrexate induction therapy; named the studies involved.

Added text to state that in a prospective randomized trial of 410 immunocompetent patients with newly diagnosed primary central nervous system lymphoma, all patients were scheduled to receive high-dose methotrexate and randomly assigned to receive WBRT or no radiation. Also added statistics about the intent-to-treat population, including data that showed the association of WBRT with a prolongation of progression-free survival but no difference in overall survival; the study lacked the power to exclude a benefit or harm from the WBRT (cited Korfel et al. as reference 46 and level of evidence 1iiDiii). In this study, 19 patients were diagnosed with intraocular involvement at diagnosis; intraocular lymphoma was an independent negative prognostic indicator (cited Kreher et al. as reference 47).

Added text to state that patients with intraocular disease and concomitant brain involvement had a worse prognosis than those with brain-involvement alone.

Added Key References for Primary CNS Lymphoma Treatment as a new section.

This summary is written and maintained by the PDQ Adult Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.

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Key References for Primary CNS Lymphoma Treatment

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About This PDQ Summary