domingo, 15 de febrero de 2026

‘Addiction machines’: Social media companies on trial, blamed for epidemic of suicides Lily Jamali | BBC | February 12, 2026

https://geneticliteracyproject.org/2026/02/12/addiction-machines-social-media-companies-on-trial-blamed-for-epidemic-of-suicides/

Unpasteurized milk scandal: 2% of the U.S. drinks unpasteurized milk but it causes 22x more infections Cambridge University Press | February 12, 2026

https://geneticliteracyproject.org/2026/02/12/unpasteurized-milk-scandal-2-of-the-u-s-drinks-unpasteurized-milk-but-it-causes-22x-more-infections/

No, supplements cannot prevent cancer or even help treat it, and they could even make things worse Mikkael Sekeres | Washington Post | February 13, 2026

https://geneticliteracyproject.org/2026/02/13/no-supplements-cannot-prevent-cancer-or-even-help-treat-it-and-they-could-even-make-things-worse/

Viewpoint—Vaccine rejectionists are trying to scare women that they are being used as ‘guinea pigs’ Aimee Pugh Bernard, David Higgins, Elana Pearl BenJoseph, Jess Steier | February 12, 2026

https://geneticliteracyproject.org/2026/02/12/viewpoint-vaccine-rejectionists-are-trying-to-scare-women-that-they-are-being-used-as-guinea-pigs/

GLP podcast: In defense of DDT—the pesticide that saved half a billion lives Cameron English, Liza Lockwood | February 13, 2026

https://geneticliteracyproject.org/2026/02/13/glp-podcast-in-defense-of-ddt-the-pesticide-that-saved-half-a-billion-lives/

Functional Food

Functional Food This hub provides a comprehensive overview and the latest news on functional foods, superfoods, and dietary components that contribute to health and disease prevention. The collection highlights bioactive compounds in foods such as lychee, chia seeds, dates, baobab fruit, and black sesame, alongside evidence-based discussions on fermented foods, postbiotics, and algae-based supplements. Readers will also find insights into the health benefits of traditional and modern diets, including the Atlantic and Washoku patterns, as well as functional beverages and plant-derived oils. By combining nutritional science, clinical research, and updates on emerging food innovations, this hub equips healthcare professionals, researchers, and health-conscious individuals with reliable knowledge to evaluate functional foods and their role in supporting long-term wellness. https://www.news-medical.net/condition/Functional-Food

Cardiologists highlight overlooked heart risks across women’s lives +++

Daily coffee intake linked to fewer atrial fibrillation relapses https://www.news-medical.net/news/20260130/Daily-coffee-intake-linked-to-fewer-atrial-fibrillation-relapses.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 The study reveals that moderate coffee consumption may lower atrial fibrillation recurrence risk post-cardioversion, highlighting coffee's potential benefits. New model predicts redo surgery risk in adult congenital heart disease https://www.news-medical.net/news/20260131/New-model-predicts-redo-surgery-risk-in-adult-congenital-heart-disease.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 Heart specialists at Mayo Clinic today presented new research at the 2026 Society of Thoracic Surgeons Annual Meeting that redo surgery for adults with congenital heart disease (CHD) remains high-risk, and a clinically applicable national risk assessment model is needed to help patients and care teams make decisions about procedures. Cardiologists highlight overlooked heart risks across women’s lives https://www.news-medical.net/news/20260203/Cardiologists-highlight-overlooked-heart-risks-across-womene28099s-lives.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 Heart disease remains the leading cause of death for women in the United States, yet awareness of cardiovascular risk—particularly among younger women and women of color—has stalled, even as rates of high blood pressure, diabetes, obesity, and high cholesterol continue to rise.

Men develop premature heart disease earlier than women

https://www.news-medical.net/news/20260202/Men-develop-premature-heart-disease-earlier-than-women.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 Researchers track heart disease from young adulthood to uncover when sex-based risk differences first emerge. In a recent study published in the Journal of the American Heart Association, a group of researchers examined sex-based differences in the age of onset of premature cardiovascular disease (CVD) and its major subtypes across adulthood.

Why cardiologist evaluation matters after non-cardiac surgery

https://www.news-medical.net/news/20260203/Why-cardiologist-evaluation-matters-after-non-cardiac-surgery.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 Many post-surgical heart injuries go unnoticed, but cardiologist input can change outcomes. In a recent study published in the European Heart Journal, researchers analyzed data from more than 1,000 patients who developed perioperative myocardial injury to explain the potential mortality benefits of including a cardiologist in non-cardiac procedures, particularly for high-risk patients.

Engineered Listeria boosts innate immunity against cancer

https://www.news-medical.net/news/20260213/Engineered-Listeria-boosts-innate-immunity-against-cancer.aspx After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system - and a potential weapon against cancer.

US drinking water kiosks sometimes contain elevated lead levels

https://www.news-medical.net/news/20260213/US-drinking-water-kiosks-sometimes-contain-elevated-lead-levels.aspx After high-profile water crises like the one in Flint, Michigan, some Americans distrust the safety of tap water, choosing to purchase drinking water from freestanding water vending machines or kiosks. Yet this more expensive water may contain different pollutants than local tap water, according to a study in ACS' Environmental Science & Technology. Researchers report that water sampled from 20 kiosks in six states sometimes contained lead at levels above public health recommendations.

Vitamin A and thyroid hormones in the retina shape fetal vision

https://www.news-medical.net/news/20260213/Vitamin-A-and-thyroid-hormones-in-the-retina-shape-fetal-vision.aspx Humans develop sharp vision during early fetal development thanks to an interplay between a vitamin A derivative and thyroid hormones in the retina, Johns Hopkins University scientists have found.

Ozempic users continue treatment when weight loss works despite side effects

https://www.news-medical.net/news/20260213/Ozempic-users-continue-treatment-when-weight-loss-works-despite-side-effects.aspx An examination of user reviews finds that people continue off-label Ozempic when it delivers results, even if side effects persist. A recent study in the Journal of Medical Internet Research examined patients’ experiences with off-label Ozempic use for weight loss and identified factors that influence user satisfaction and treatment discontinuation.

Stopping vertical transmission requires global resolve The Lancet Microbe ++... ++

Stopping vertical transmission requires global resolve The Lancet Microbe https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00273-3/fulltext?dgcid=raven_jbs_etoc_email Feb 2026 Volume 7Number 2 https://www.thelancet.com/journals/lanmic/issue/vol7no2/PIIS2666-5247(26)X2001-8 Convergence and global molecular epidemiology of Klebsiella pneumoniae plasmids harbouring the iuc3 virulence locus: a population genomic analysis Marjorie J Gibbon, PhDa,∗ ∙ Natacha Couto, PhDa,b,∗ ∙ Keira Cozens, MSca ∙ Samia Habib, PhDa ∙ Lauren Cowley, PhDa ∙ Prof David M Aanensen, PhDb ∙ et al. https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00164-8/fulltext?dgcid=raven_jbs_etoc_feature_lanmic Impact of a multicomponent training intervention (Clean FrontLine) on microbiological cleanliness in Cambodian referral hospitals: a multicentre, stepped-wedge, cluster-randomised trial Giorgia Gon, PhDa giorgia.gon@lshtm.ac.uk ∙ Sokvy Ma, MScb ∙ Alexander M Aiken, PhDa ∙ Prof Stephanie J Dancer, PhDc ∙ Prof Wendy J Graham, PhDa ∙ Stephen Nash, MScd ∙ et al. https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00190-9/fulltext?dgcid=raven_jbs_etoc_feature_lanmic

Nonmetastatic nasopharyngeal carcinoma: in search of safer therapies The Lancet Regional Health – Americas +++ +...

E-cigarettes versus combination nicotine replacement therapy following a recent failed quit attempt: a pragmatic randomized trial through state tobacco quitlines Theodore L. Wagenera katrina.vickerman@gmail.com ∙ Alice Hintona ∙ Theodore M. Braskya ∙ Yoo Jin Choa ∙ Laura A. Beebeb ∙ Michael S. Businelleb ∙ et al. https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(25)00362-X/fulltext?dgcid=raven_jbs_etoc_feature_lanam Incidence rates of twelve chronic diseases/conditions in US adults: findings from a population-based study Richard L. Nahina Nahinr@mail.nih.gov ∙ Termeh Feinbergb ∙ Hanna Grol-Prokopczykc ∙ Flavia P. Kaposd ∙ Kerri Murraye ∙ Remle Scottf ∙ et al. https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(25)00353-9/fulltext?dgcid=raven_jbs_etoc_feature_lanam Nonmetastatic nasopharyngeal carcinoma: in search of safer therapies The Lancet Regional Health – Americas https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(26)00050-5/fulltext?dgcid=raven_jbs_etoc_email Feb 2026 Volume 54 https://www.thelancet.com/journals/lanam/issue/vol54nonull/PIIS2667-193X(25)X0013-2

Hot Topics from Berlin 2025: What Experts Say About the Future of Metastatic Breast Cancer Care Authors: Paolo Tarantino, MD, PhD; Valentina Guarneri, MD, PhD; Rebecca A. Dent, MD

https://www.medscape.org/viewarticle/hot-topics-berlin-2025-what-experts-say-about-future-2025a1000x8r?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260214-OUS-HONC-hot-topics-berlin-2025-what-experts-say-about-future-2025a1000x8r-cta

Latest Advances in mHSPC: An Update From Berlin 2025 Authors: Karim Fizazi, MD, PhD

https://www.medscape.org/viewarticle/latest-advances-mhspc-update-berlin-2025-2025a1000vlk?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260214-OUS-HONC-latest-advances-mhspc-update-berlin-2025-2025a1000vlk-cta

Highlights From the Annual Neuro-Oncology Conference: Redefining IDH-Mutant Glioma Management Authors: Evanthia Galanis, MD; Shawn Hervey-Jumper, MD; Katherine B. Peters, MD, PhD, FAAN; Matthias Preusser, MD

https://www.medscape.org/viewarticle/1003198?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260214-OUS-HONC-1003198-cta

Rare Clinical Spotlight: Exploring Castleman Disease, Cold Agglutinin Disease, and Acute Intermittent Porphyria Authors: Ariela Noy, MD; Sudipto Mukherjee, MD, PhD, MPH; Angelika Erwin, MD, PhD; Bruce Wang, MD; Catherine Broome, MD; Ilene Weitz, MD

https://www.medscape.org/viewarticle/rare-clinical-spotlight-exploring-castleman-disease-cold-2025a100104i?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260215-OUS-HONC-rare-clinical-spotlight-exploring-castleman-disease-cold-2025a100104i-cta

Beyond Cure: Long-Term Risks After Childhood Cancer ++++ +++ International Childhood Cancer Day

Late Effects Beyond Cure: Long-Term Risks After Childhood Cancer Cured as Children, At Risk as Adults? Long-Term Outcomes After Childhood Cancer Maurie Markman, MD https://www.medscape.com/viewarticle/cured-children-risk-adults-long-term-outcomes-after-2026a10000dr?ecd=mkm_ret_260215_mscpmrk-OUS_InFocus_etid8099638&uac=148436CN&impID=8099638 January 30, 2026 Certain Childhood Cancer Therapies Tied to Valvulopathy Certain Childhood Cancer Therapies Tied to Valvulopathy Edited by Gargi Mukherjee https://www.medscape.com/viewarticle/certain-childhood-cancer-therapies-tied-valvulopathy-2025a1000rh6?ecd=mkm_ret_260215_mscpmrk-OUS_InFocus_etid8099638&uac=148436CN&impID=8099638 October 13, 2025 1 in 3 Childhood Cancer Survivors Face Endocrine Issues 1 in 3 Childhood Cancer Survivors Face Endocrine Issues Edited by Vinod Rane, BS Pharm https://www.medscape.com/viewarticle/1-3-childhood-cancer-survivors-face-endocrine-issues-2026a10002bc?ecd=mkm_ret_260215_mscpmrk-OUS_InFocus_etid8099638&uac=148436CN&impID=8099638 Medscape UK January 27, 2026 Childhood Cancer Survivors Face Long-Term Meningioma Risk Childhood Cancer Survivors Face Long-Term Meningioma Risk Edited by Gargi Mukherjee https://www.medscape.com/viewarticle/childhood-cancer-survivors-face-long-term-meningioma-risk-2025a1001026?ecd=mkm_ret_260215_mscpmrk-OUS_InFocus_etid8099638&uac=148436CN&impID=8099638 December 22, 2025 Support & Prevention Teen Exercise May Reshape Breast Cancer Risk Teen Exercise May Reshape Breast Cancer Risk Edited by Katie Lennon https://www.medscape.com/viewarticle/teen-exercise-may-reshape-breast-cancer-risk-2026a10002ji?ecd=mkm_ret_260215_mscpmrk-OUS_InFocus_etid8099638&uac=148436CN&impID=8099638 January 27, 2026 The Lingering Fear After Beating Childhood Cancer The Lingering Fear After Beating Childhood Cancer Maurie Markman, MD https://www.medscape.com/viewarticle/lingering-fear-after-beating-childhood-cancer-2025a10006qo?ecd=mkm_ret_260215_mscpmrk-OUS_InFocus_etid8099638&uac=148436CN&impID=8099638 April 01, 2025 Travel Help Announced for Families of Children With Cancer Travel Help Announced for Families of Children With Cancer Dr Sheena Meredith https://www.medscape.com/viewarticle/travel-help-announced-families-children-cancer-2026a10003e1?ecd=mkm_ret_260215_mscpmrk-OUS_InFocus_etid8099638&uac=148436CN&impID=8099638 Medscape UK February 03, 2026

sábado, 14 de febrero de 2026

Editorial e1 Management of diabetes during pregnancy The Lancet Obstetrics, Gynaecology, & Women's Health +++...

Interval cancer, sensitivity, and specificity comparing AI-supported mammography screening with standard double reading without AI in the MASAI study: a randomised, controlled, non-inferiority, single-blinded, population-based, screening-accuracy trial Jessie Gommers, MSca,b ∙ Veronica Hernström, MDb,c ∙ Viktoria Josefsson, MDb,c ∙ Hanna Sartor, PhDb,d ∙ David Schmidt, MDb,d ∙ Annie Hjelmgren, MDd ∙ et al. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)02464-X/abstract?utm_campaign=infocusalerts-obgyn&utm_medium=email&dgcid=hubspot_email_infocusalerts-obgyn_feature&_hsenc=p2ANqtz-_7M80FSuvslzvwWswPk3Na_r7ibyL7ZWu-Yyskp5PkSgptvk--XgD6AVn4ZqB_lVgX0b_yfgEwflgJOIOShdkZbORCyA&_hsmi=403618992&utm_content=403597469&utm_source=hs_email Epidemiological and genetic evidence for shared mechanisms between migraine and pre-eclampsia: a nationwide cohort and genetic risk study in Denmark Olafur B Davidsson, PhDa,b,c,d oda@cancer.dk ∙ Klaus Rostgaard, MSca,b ∙ Ragnar P Kristjánsson, PhDb,c,d,e ∙ Jojo Biel-Nielsen Dietz, MD PhDb ∙ Noomi Vainer, MDb ∙ Lisette J A Kogelman, PhDc,d ∙ et al. https://www.thelancet.com/journals/lanogw/article/PIIS3050-5038(25)00114-1/abstract?utm_campaign=infocusalerts-obgyn&utm_medium=email&dgcid=hubspot_email_infocusalerts-obgyn_feature&_hsenc=p2ANqtz-9wnhB4dqgJZHH1LzfzNxDpAIEL_AFDcwlALnxma_7O-4sP49NMGtP6s5DSOh5NvtvVh_j8rOuLhX7hTpc-K5r9IPSgMQ&_hsmi=403618992&utm_content=403597469&utm_source=hs_email Editorial e1 Management of diabetes during pregnancy The Lancet Obstetrics, Gynaecology, & Women's Health https://www.thelancet.com/journals/lanogw/issue/vol2no1/PIIS3050-5038(25)X0006-6

From Cookies To Caregivers: 7 Types Of Grandparents By Ivanhoe Broadcast News on February 20, 2026

https://www.ivanhoe.com/?p=36685&preview=1&_ppp=2dbe0e6937 Orlando, Fla. (Ivanhoe Newswire) — By age 65, AARP reports 96 percent of Americans are grandparents. Grandparents play an important role in children’s lives. Studies show kids who have close relationships with grandparents have fewer emotional and behavioral problems and better social skills. Now, researchers have identified seven distinct grandparenting styles and chances are, you might recognize yourself in more than one of them.

Are You Scam Proof? Who Is Really At Risk? By Ivanhoe Broadcast News on February 19, 2026

https://www.ivanhoe.com/?p=36682&preview=1&_ppp=ca5851d049 Orlando, Fla. (Ivanhoe Newswire) — The New York Times reports Americans over 70 control $53 trillion in wealth and cybercrime against elders is skyrocketing! The Federal Trade Commission reports older adults lost 2.4 billion dollars to scams last year, a sharp increase from just a few years ago. Now, a new study is taking a closer look at what really makes someone vulnerable and why even people who think they’re scam-proof may not be.

Modern Love: Dating Trends Redefining Valentine’s Day By Ivanhoe Broadcast News on February 18, 2026

https://www.ivanhoe.com/?p=36679&preview=1&_ppp=b8b66a7765 Orlando, Fla. (Ivanhoe Newswire) — About 60 percent of people worldwide celebrate Valentine’s Day but for many, the holiday is no longer just about romantic love. From friendship-first celebrations to new dating rules and tech-driven matchmaking, the way people connect is evolving.

Love, Lies, And Money: Inside Today’s Romance Scams By Ivanhoe Broadcast News on February 17, 2026

https://www.ivanhoe.com/?p=36676&preview=1&_ppp=56641a44c9 Orlando, Fla. (Ivanhoe Newswire) — Worldwide, nearly one in four people say they’ve been scammed online. One of the fastest growing, and most devastating type is the romance scam, where fraudsters pretend to fall in love, then ask for money. It’s now the third most common scam targeting adults 60 and older.

Fuel Like A Champion By Ivanhoe Broadcast News on February 16, 2026

https://www.ivanhoe.com/?p=36673&preview=1&_ppp=23b3277d32 Orlando, Fla. (Ivanhoe Newswire) — While the world is watching the Winter Olympics, there’s a lot more going on behind the scenes than gold medals and record-breaking runs. Olympians are training and fueling their bodies for peak performance. But experts say you don’t have to be an elite athlete to apply some of those same principles to your own workouts.

How and when to screen for retinopathy in type 1 diabetes (Medscape AI)

https://www.medscape.com/ai-search?query=How%20and%20when%20to%20screen%20for%20retinopathy%20in%20type%201%20diabetes&ecd=wnl_tp10_daily_260203_MSCPEDIT_etid8076840&uac=148436CN&impID=8076840

What are the initial treatment options for Alzheimer's dementia? (Medscape AI)

https://www.medscape.com/ai-search?query=What%20are%20the%20initial%20treatment%20options%20for%20Alzheimer%27s%20dementia%3F&ecd=wnl_tp10_daily_260131_MSCPEDIT_etid8067895&uac=148436CN&impID=8067895

How should clinicians address vaccine hesitancy related to measles or recent schedule changes? (Medscape AI)

https://www.medscape.com/ai-search?query=How%20should%20clinicians%20address%20vaccine%20hesitancy%20related%20to%20measles%20or%20recent%20schedule%20changes%3f&ecd=mkm_ret_260202_mscpmrk_idhiv_vaccine_etid8068674&uac=148436CN&impID=8068674

How do GLP1s and metformin impact dementia risk? (Medscape AI)

https://www.medscape.com/ai-search?query=How%20do%20GLP1s%20and%20metformin%20impact%20dementia%20risk%3F&ecd=wnl_tp10_daily_260201_MSCPEDIT_etid8067932&uac=148436CN&impID=8067932

What is the A1C target for a frail, elderly patient with type 2 diabetes? (Medscape AI)

https://www.medscape.com/ai-search?query=What%20is%20the%20A1C%20target%20for%20a%20frail%2C%20elderly%20patient%20with%20type%202%20diabetes%3F&ecd=wnl_tp10_daily_260202_MSCPEDIT_etid8074007&uac=148436CN&impID=8074007

How to determine onset of perimenopause and menopause? (Medscape AI)

https://www.medscape.com/ai-search?query=How%20to%20determine%20onset%20of%20perimenopause%20and%20menopause%3F&ecd=wnl_tp10_daily_260204_MSCPEDIT_etid8079796&uac=148436CN&impID=8079796

Popular weight-loss drugs linked to rare 'pirate disease,' researchers warn By Angelica Stabile Fox News Published February 13, 2026 7:00am EST

Popular weight-loss drugs linked to rare 'pirate disease,' researchers warn GLP-1 medications may contribute to malnutrition as clinical trials fail to monitor food intake Angelica Stabile By Angelica Stabile Fox News Published February 13, 2026 7:00am EST https://www.foxnews.com/health/popular-weight-loss-drugs-linked-rare-pirate-disease-scurvy-researchers-warn?lid=zoopmps49qu6

James Van Der Beek’s death highlights alarming colon cancer rise in younger adults By Angelica Stabile , Melissa Rudy Fox News Published February 12, 2026 2:41pm EST

James Van Der Beek’s death highlights alarming colon cancer rise in younger adults Doctors reveal why colon cancer is now the top deadliest cancer among those 50 and under Angelica Stabile By Angelica Stabile , Melissa Rudy Fox News Published February 12, 2026 2:41pm EST https://www.foxnews.com/health/james-van-der-beeks-death-highlights-alarming-colon-cancer-rise-younger-adults?lid=hz6ixf6p5dwy

Revisiting concepts of mitochondrial transport and energy metabolism in health and cancer Salvatore Passarella* [1]

https://www.academia.edu/2837-4010/3/4/10.20935/AcadBiol8065 Although our understanding of mitochondrial processes has expanded substantially, the contributions of metabolite transport and energy metabolism to mitochondrial function in health and disease remain incompletely characterized. The transport and metabolism of key metabolites, including oxaloacetate, L-lactate and D-lactate, are mediated by distinct transporters and mitochondrial enzymes that together influence cellular bioenergetics in normal and neoplastic tissues. This review reassesses mechanistic aspects of mitochondrial shuttles, gluconeogenesis and the Cori cycle, the mitochondrial transport and oxidation of L-lactate, the Warburg effect, and the methylglyoxal pathway. Emphasis is placed on evidence supporting mitochondrial uptake and metabolism of oxaloacetate and lactate isomers and on the implications of these processes for redox balance, anaplerosis, and biosynthesis in cancer. I propose that a fuller integration of metabolite transport phenomena into models of cellular metabolism is necessary to refine current concepts of mitochondrial physiology and pathophysiology. The need for echocardiographic reference values in adults over 80 years of age Miguel Quintana, Mira Carling, Anders Olofsson, Dag Isaksson, Jenny Fahlen, Elin Kärrman, Fredrik Pihl, Roland Forsberg, Björn Persson, Alen Lovric, Thomas Gustafsson, Karin Bouma Volume 4, Issue 1 https://www.academia.edu/journals/academia-biology/articles?source=journal-top-nav

Most Read Cancer Science & Oncogenesis +...

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_260213

Redefining Standards in Bladder Cancer: The Expanding Role of Immunotherapy Authors: Andrea Necchi, MD; James W. F. Catto, MB ChB, PhD, FRCS; Maria De Santis, MD

https://www.medscape.org/viewarticle/redefining-standards-bladder-cancer-expanding-role-2025a1000ws0?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260213-OUS-HONC-redefining-standards-bladder-cancer-expanding-role-2025a1000ws0-cta

Weekly Rundown: Novo Nordisk sues Hims over unapproved Wegovy and Ozempic copies Legal battles, FDA setbacks, billion-dollar bets, and more led the news this week.

https://www.drugdiscoverynews.com/weekly-rundown-novo-nordisk-sues-hims-over-unapproved-wegovy-and-ozempic-copies-17008?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_Gt_DXmJgqLFrixOf4MTFoORzUVH4S-x6-G-juLgW9jw2KWbZHSgfa28ep_613FDDakOT73Oreaqi_6N_n9JIufrIrYQ&_hsmi=403580108&utm_content=403580108&utm_source=hs_email

Hormone Replacement Therapies Can Help Women with Bothersome Menopausal Symptoms

https://www.fda.gov/consumers/consumer-updates/hormone-replacement-therapies-can-help-women-bothersome-menopausal-symptoms?utm_medium=email&utm_source=govdelivery The effects of menopause can make a woman’s daily life much harder, and therapies approved by the U.S. Food and Drug Administration can help. But too many women might not use these treatments to lessen their menopause symptoms because of the risks associated with these drugs described in the drug labels’ boxed warnings (the FDA’s most prominent warnings).

Assessing Conditioning Regimens for HSCT: Optimizing Patient Outcomes Authors: Mohamad Mohty, MD, PhD; Daniele Avenoso, MD, PhD; Simona Sica, MD, PhD; Sergio Giralt, MD, FACP, FASTCT

https://www.medscape.org/viewarticle/1003061?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260213-OUS-HONC-1003061-cta

How Are ADCs Shaping the Future of Early Breast Cancer Care? Latest Insights and Emerging Strategies Authors: Nadia Harbeck, MD, PhD; Giuseppe Curigliano, MD, PhD

https://www.medscape.org/viewarticle/how-are-adcs-shaping-future-early-breast-cancer-care-latest-2025a1000yca?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260214-OUS-HONC-how-are-adcs-shaping-future-early-breast-cancer-care-latest-2025a1000yca-cta

viernes, 13 de febrero de 2026

FDA Approves Labeling Changes to Menopausal Hormone Therapy Products

https://www.fda.gov/news-events/press-announcements/fda-approves-labeling-changes-menopausal-hormone-therapy-products?utm_medium=email&utm_source=govdelivery The U.S. Food and Drug Administration has approved drug labeling changes to six menopausal hormone therapy products, also known as hormone replacement therapy (HRT), to clarify risk considerations for these drugs. Specifically, risk statements related to cardiovascular disease, breast cancer and probable dementia were removed from the “boxed warning,” the agency’s most prominent safety-related warning. “This decision reflects our commitment to follow the science wherever it leads and to correct course when the evidence demands it,” Health and Human Services Secretary Robert F. Kennedy, Jr. said. “By removing these boxed warnings, we ensure that women receive accurate information about hormone therapy—free from exaggeration or fear. A healthcare system worthy of public trust tells the truth, updates its guidance as science evolves, and respects women’s ability to make informed choices about their own health.” The FDA initiated the removal of these warnings in November 2025, following a comprehensive review of the scientific literature. At the FDA’s request, 29 drug companies have submitted proposed labeling changes. This first batch of six products with approved labeling changes includes products from each of the four categories of HRT for menopausal women: Systemic combination therapy (estrogen and progestogen) Systemic estrogen-alone therapy Systemic progestogen-alone therapy for women with a uterus using systemic estrogen Topical vaginal estrogen therapy “With today’s action, we are delivering on our promise to make sure women have accurate, scientifically grounded information about the potentially life-changing benefits of HRT,” said FDA Commissioner Marty Makary, M.D., M.P.H. “Women face symptoms of menopause that can last for years, and our efforts will help these women make well-informed medical decisions.” Menopause is a normal life stage, but its symptoms can significantly reduce quality of life. Common symptoms include hot flashes and night sweats (called vasomotor symptoms or VMS); vaginal, vulvar, and urinary tract changes caused by lower estrogen levels; and osteoporosis (thinning bones), which increases fracture risk. The FDA has approved multiple hormone therapies for moderate-to-severe hot flashes, vaginal dryness and discomfort, and preventing bone loss. In addition, randomized studies show that women who initiate HRT within 10 years of the onset of menopause (generally before age 60) have a reduction in all-cause mortality and fractures. Just a small fraction of women who could benefit from these treatments, however, are using them. In 2020, about 41 million U.S. women were ages 45–64 — yet only about 2 million women ages 46–65 received a hormone-therapy prescription. Today’s action will allow women, working with their health care professionals, to make better-informed decisions about their treatment plan for menopause symptoms. Women are encouraged to consult the drug label, available here, for more detailed information about the benefits and risks of these products. Menopausal Hormone Therapies with Updated Prescribing Information https://www.fda.gov/drugs/drug-safety-and-availability/menopausal-hormone-therapies-updated-prescribing-information?utm_medium=email&utm_source=govdelivery

Statin safety: when warnings outlive the evidence The Lancet ++... ´+

Statin safety: when warnings outlive the evidence The Lancet https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00303-X/fulltext?dgcid=raven_jbs_etoc_email Feb 14, 2026 Volume 407Number 10529p649-732 https://www.thelancet.com/journals/lancet/issue/vol407no10529/PIIS0140-6736(26)X2004-9 Tetanus Prof Önder Ergönül, MD MPHa,b oergonul@ku.edu.tr ∙ Selin Kolsuz, MDa ∙ Prof J Peter Figueroa, MBBS PhD https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01579-X/abstract?dgcid=raven_jbs_etoc_feature_lancet

Thawing a Frozen Shoulder Arif Musa, MD; Ali Harb, MD | February 4, 2026 |

https://reference.medscape.com/slideshow/Frozen-Shoulder-6019131?ecd=wnl_critimg_260213_mscpref_etid8099014&uac=148436CN&impID=8099014 Frozen shoulder is a condition marked by progressive stiffness and pain that eventually resolves through a "thawing" phase. While traditional treatments range from physical therapy to surgery, new techniques like Adhesive Capsulitis Embolization (ACE) offer additional relief. This presentation reviews current treatment efficacy and new clinical developments.

Alcohol guidance in US dietary guidelines: a step backwards The Lancet Gastroenterology & Hepatology ++... ++

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(26)00016-6/fulltext?dgcid=raven_jbs_etoc_email Mar 2026 Volume 11Number 3p175-266, e2-e5 https://www.thelancet.com/journals/langas/issue/vol11no3/PIIS2468-1253(26)X2001-5 Definitions, diagnosis, management, and outcomes of upper gastrointestinal Crohn's disease: an international, expert RAND/UCLA appropriateness study Nathaniel A Cohen, MDa nathanielac@tlvmc.gov.il ∙ Prof Dominik Bettenworth, MDb,c ∙ Neta Sror, MDd ∙ Raneem Khedraki, PhDe ∙ Qijun Yang, MSe ∙ Prof Maria T Abreu, MDf ∙ et al. https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00347-4/abstract?dgcid=raven_jbs_etoc_feature_langas Appendicectomy versus switching to a JAK inhibitor in inducing remission in patients with active ulcerative colitis after biologic therapy failure (COSTA): 1-year results of a multicentre, prospective, cohort study Eva Visser, MD PhDa ∙ Maud A Reijntjes, MD PhDa ∙ Lianne Heuthorst, MD PhDa ∙ Merle E Stellingwerf, MD PhDa ∙ Rachel West, MD PhDb ∙ Koen van Dongen, MD PhDc ∙ et al. https://www.thelancet.com/journals/langas/article/PIIS2468-1253(25)00291-2/abstract?dgcid=raven_jbs_etoc_feature_langas

Editorial e75 GLP-1 receptor agonists in rheumatic disease The Lancet Rheumatology ++... +

Assessing clinical and cost effectiveness of total versus partial knee replacement (TOPKAT): 10-year follow-up of a multicentre, randomised controlled trial Prof David J Beard, DPhila,d david.beard@ndorms.ox.ac.uk ∙ Loretta J Davies, DPhila ∙ Prof Jonathan A Cook, PhDa ∙ Prof Graeme MacLennan, MScc ∙ Jemma Hudson, PhDc ∙ Prof Andrew J Price, FRCSa ∙ et al. https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(25)00250-4/fulltext?dgcid=hubspot_update_feature_updatealerts_lanrhe&utm_campaign=update-lanrhe&utm_medium=email&_hsenc=p2ANqtz-8EvPIK-fX0yJMuYr9c9Nwpm9DIZRxFz0gOGNEBqrxbEH7fNoROnm7ue3Totl3pYHkiyW_KNOoBIDS2jgAY5gRQeicV4w&_hsmi=403170350&utm_content=402699227&utm_source=hs_email Editorial e75 GLP-1 receptor agonists in rheumatic disease The Lancet Rheumatology https://www.thelancet.com/journals/lanrhe/issue/vol8no2/PIIS2665-9913(26)X2001-X Trends in mortality due to haemophagocytic lymphohistiocytosis across 29 European countries from 2011 to 2021: a retrospective, international, population-based study Leher Gumber, MSca,b ∙ Reza Omidvar, MScc ∙ Francesca Gonnelli, PhDd,e ∙ Adam Taylor, MEngc ∙ Thomas Trimble, BScc ∙ Mark Bishton, PhDe,f ∙ et al. https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(25)00292-9/fulltext?dgcid=hubspot_update_feature_updatealerts_lanrhe&utm_campaign=update-lanrhe&utm_medium=email&_hsenc=p2ANqtz-9aoZkd0o9FGb_nWrlnoJRWFpic0JTPGPQ8_H80f5KTTSL4xH3EWoRoQCgcTqDH1rl4l3LjAYNXar7gys7ODjs8TLebRw&_hsmi=403170350&utm_content=402699227&utm_source=hs_email

Gene therapy startups push past old limits to reach more patients With gene therapy now a clinical reality, innovators are designing delivery systems that can sustain lifelong correction, handle complex genes, and make treatments accessible to more patients. +++++

https://www.drugdiscoverynews.com/gene-therapy-startups-push-past-old-limits-to-reach-more-patients-17003 In 2026, drug discovery faces a higher bar Biopharma’s recovery is real, but the data show a sector that now rewards validated biology, late-stage execution, and commercial relevance. https://www.drugdiscoverynews.com/in-2026-drug-discovery-faces-a-higher-bar-16997 A faster route to active GPCRs GPCRs drive a huge portion of today’s drug market, but producing them in a functional form remains a major bottleneck for discovery and structural studies. https://www.drugdiscoverynews.com/a-faster-route-to-active-gpcrs-16977 Exploring the tiny robots improving drug delivery from inside the body Moved by magnets or ultrasound waves, these tiny robots make delivering drugs more accurate and effective. https://www.drugdiscoverynews.com/exploring-the-tiny-robots-improving-drug-delivery-from-inside-the-body-16998 Sustained-release drug delivery targets pediatric inherited retinal disease PolyActiva and RareSight are pairing pro-drug chemistry with targeted ocular delivery to address early-stage barriers in rare pediatric retinal disorders. https://www.drugdiscoverynews.com/sustained-release-drug-delivery-targets-pediatric-inherited-retinal-disease-16945

Highlights From the Annual Neuro-Oncology Conference: Integrating IDH Inhibitor Therapy Into Glioma Care Authors: Maciej Mrugala, MD, PhD, MPH; Rimas V. Lukas, MD; Yoshie Umemura, MD

https://www.medscape.org/viewarticle/1003175?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260212-OUS-HONC-1003175-cta

Pediatric Low-Grade Glioma With BRAF Alterations: Stories, Science, and Strategies Authors: Darren Hargrave, MBChB, MD; Cameron Miller; Enrico Opocher, MD; Sébastien Perreault, MD, FRCPC

https://www.medscape.org/viewarticle/pediatric-low-grade-glioma-braf-alterations-stories-science-2025a1000x3w?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260212-OUS-HONC-pediatric-low-grade-glioma-braf-alterations-stories-science-2025a1000x3w-cta

Understanding Epilepsy A Surge of Signals

https://newsinhealth.nih.gov/2026/02/understanding-epilepsy

The Heart Truth® Heart disease is the leading cause of death in the United States. But you can do a lot to protect your heart.

The Heart Truth® Heart disease is the leading cause of death in the United States. But you can do a lot to protect your heart. https://www.nhlbi.nih.gov/health-topics/education-and-awareness/heart-truth

People with dementia prescribed risky drugs

https://www.nih.gov/news-events/nih-research-matters/people-dementia-prescribed-risky-drugs At a Glance Researchers found that many older adults with dementia were prescribed medications that can increase the risk of confusion, falls, and hospitalization. Reducing such unnecessary prescriptions could improve the quality of care for older adults. NIH Research Matters February 10, 2026 Edition https://www.nih.gov/news-events/nih-research-matters

Cancer Causes and Prevention

https://www.cancer.gov/about-cancer/causes-prevention Cancer prevention is action taken to lower the risk of getting cancer. This can include maintaining a healthy lifestyle, avoiding exposure to known cancer-causing substances, and taking medicines or vaccines that can prevent cancer from developing.

Atopic Dermatitis (EnglishEspañol繁體中文한국어tiếng Việt)

https://www.niams.nih.gov/health-topics/atopic-dermatitis Atopic dermatitis, often referred to as eczema, is a chronic (long-lasting) disease that causes inflammation, redness, and irritation of the skin. It is a common condition that usually begins in childhood; however, anyone can get the disease at any age. Atopic dermatitis is not contagious, so it cannot be spread from person to person.

Recommended CME For You: +++ +++ +++ +

The Rise of Protein Degraders for Hematologic Malignancies: Exploring the Latest Data From ASH 2024 CME The Rise of Protein Degraders for Hematologic Malignancies: Exploring the Latest Data From ASH 2024 Authors: Sagar Lonial, MD, FACP; Constatine Tam, MBBS, MD, FRACP, FRCPath; Julio Chavez, MD, MS https://www.medscape.org/viewarticle/1002295?sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu Sharing Expert Minds in Lung Cancer and Lung Neuroendocrine Tumors Delivering Optimal Patient Care CME Sharing Expert Minds in Lung Cancer and Lung Neuroendocrine Tumors Delivering Optimal Patient Care Authors: Martin Reck, MD, PhD; Catherine Bouvier; Melanie Lucas; Abdul Masoor, MBChB, PhD, MRCP; Marianne Pavel, MD https://www.medscape.org/viewarticle/1002284?sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu AL Amyloidosis in Focus: Ongoing Innovations and Applicability to Practice CME AL Amyloidosis in Focus: Ongoing Innovations and Applicability to Practice Authors: Kevin M. Alexander, MD; Vaishali Sanchorawala, MD; Pedro Vianna, MD; Shahzad Raza, MD, FACP https://www.medscape.org/viewarticle/al-amyloidosis-focus-ongoing-innovations-and-applicability-2025a100078z?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu Myelofibrosis-Associated Anemia: Burden, Management, and Future Directions CME Myelofibrosis-Associated Anemia: Burden, Management, and Future Directions Authors: Francesca Palandri, MD; Jean-Jacques Kiladjian, MD, PhD; Jon Mathias https://www.medscape.org/viewarticle/1002370?sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu Shaping the Future of Muscle-Invasive Bladder Cancer Care: Immunotherapy in Focus CME Shaping the Future of Muscle-Invasive Bladder Cancer Care: Immunotherapy in Focus Authors: Andrea Necchi, MD; James W. F. Catto, MB, ChB, PhD, FRCS; Enrique Grande, MD, PhD https://www.medscape.org/viewarticle/1002445?sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu Virtual Simulations: Managing the Patient With HR+/HER2- Early Breast Cancer Through a Multidisciplinary Approach CME Virtual Simulations: Managing the Patient With HR+/HER2- Early Breast Cancer Through a Multidisciplinary Approach Authors: Manali Bhave, MD; Jane Meisel, MD https://www.medscape.org/viewarticle/1002474?sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu Bridging Gaps in Myelofibrosis Care: Collaborative Strategies for Anemia Management CME Bridging Gaps in Myelofibrosis Care: Collaborative Strategies for Anemia Management Authors: Claire N. Harrison, DM, FRCP, FRCPath; Haifa Kathrin Al-Ali, MD; Claire Woodley https://www.medscape.org/viewarticle/1002428?sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu Think You Know IDH-Mutant Glioma? Test Your Clinical Expertise on the Latest Advances CME Think You Know IDH-Mutant Glioma? Test Your Clinical Expertise on the Latest Advances Authors: Patrick Y. Wen, MD https://www.medscape.org/viewarticle/think-you-know-idh-mutant-glioma-test-your-clinical-2025a1000bve?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu New Standards in Diffuse Lower-Grade Gliomas: Integrative Management From Surgery to Survivorship CME Highlights from the Annual Neurosurgical Conference: New Standards in Diffuse Lower-Grade Glioma Authors: Mitchel S. Berger, MD; Macarena de la Fuente, MD; Michael Lim, MD https://www.medscape.org/viewarticle/1002598?sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu H3 K27M-Mutant Glioma: A 360° View of Science, Physician Insights, and Patient Perspectives CME H3 K27M-Mutant Glioma: A 360° View of Science, Physician Insights, and Patient Perspectives Authors: Stephen J. Bagley, MD, MSCE; Charles Eberhart, MD, PhD; Carl Koschmann, MD; Ashley L. Sumrall, MD, FACP, FASCO; Michelle Sherman https://www.medscape.org/viewarticle/h3-k27m-mutant-glioma-360-view-science-physician-insights-2025a1000gki?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_invit_mscpedu

Esketamine treatments for severe depression February 9, 2026 Jeff Hoelscher Public Affairs Officer, VA Columbia Missouri Health care System

https://news.va.gov/144924/esketamine-treatments-for-severe-depression/

Skin in the Game: Advancing Collaborative Care in NMSC Authors: David Miller, MD, PhD; Anokhi Jambusaria-Pahlajani, MD, MSCE; Vernon Sondak, MD

https://www.medscape.org/viewarticle/skin-game-advancing-collaborative-care-nmsc-2026a1000431?page=1

Medscape Now! The Hidden Dangers of Self-Treatment With Botulinum Toxin Authors: ​Naseem Bazargan, MPH

https://www.medscape.org/viewarticle/medscape-now-hidden-dangers-self-treatment-botulinum-toxin-2026a10004hi?page=1

Navigating Advances in TRK Fusion-Positive Cancers: A Collaborative Journey From Testing to Therapy Authors: David S. Hong, MD; Theodore W. Laetsch, MD; Jonathan C. Trent, MD, PhD

https://www.medscape.org/viewarticle/navigating-advances-trk-fusion-positive-cancers-2025a1000z5i?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260213-OUS-HONC-navigating-advances-trk-fusion-positive-cancers-2025a1000z5i-cta

Nearly 38% of Cancers Potentially Avoidable, Global Study Finds Frederik Joelving February 12, 2026 ++++

Nearly 38% of Cancers Potentially Avoidable, Global Study Finds Frederik Joelving https://www.medscape.com/viewarticle/nearly-38-cancers-potentially-avoidable-global-study-finds-2026a10004k6 February 12, 2026 How to Outsmart Ovarian Cancer With One Surgery Megan Brooks https://www.medscape.com/viewarticle/how-outsmart-ovarian-cancer-one-surgery-2026a10004hn February 12, 2026 Robot-Assisted CT-Guided Cryoablation Shows High Precision in Treating Pulmonary Metastases Edited by Vineeta Teotia https://www.medscape.com/viewarticle/robot-assisted-ct-guided-cryoablation-shows-high-precision-2026a10004bm Medscape UK February 13, 2026 Study: Cutaneous T-Cell Lymphoma Increasing Among US Children, Young Adults Edited by Deepa Varma https://www.medscape.com/viewarticle/study-cutaneous-t-cell-lymphoma-increasing-among-us-children-2026a10004ly February 13, 2026

New Fat Math: What to Tell Patients About Dairy | GLP-1 Drugs: New Questions on Mental Health & Sarcopenia +++++ +++

The New Fat Math: What to Tell Patients About Dairy The New Fat Math: What to Tell Patients About Dairy Lisa O’Mary https://www.medscape.com/viewarticle/new-fat-math-what-tell-patients-about-dairy-2026a10003hk?ecd=mkm_ret_260213_mscpmrk-OUS_ICYMI_etid8093905&uac=148436CN&impID=8093905 February 04, 2026 GLP-1 Drugs: New Questions on Mental Health & Sarcopenia GLP-1 Drugs: New Questions on Mental Health and Sarcopenia Jean-Bernard Gervais https://www.medscape.com/viewarticle/glp-1-drugs-new-questions-mental-health-and-sarcopenia-2026a10003ib?ecd=mkm_ret_260213_mscpmrk-OUS_ICYMI_etid8093905&uac=148436CN&impID=8093905 Medscape Europe February 04, 2026 Do Certain Diabetes Medications Increase Depression Risk? Do Certain Diabetes Medications Increase Depression Risk? Edited by Devyani Gholap https://www.medscape.com/viewarticle/do-certain-diabetes-medications-increase-depression-risk-2026a10003ay?ecd=mkm_ret_260213_mscpmrk-OUS_ICYMI_etid8093905&uac=148436CN&impID=8093905 February 03, 2026 Is Assisted Death Always Peaceful? We Simply Don’t Know Is Assisted Death Always Peaceful? Lack of Data Means We Simply Don’t Know Manuela Callari https://www.medscape.com/viewarticle/assisted-death-always-peaceful-lack-data-means-we-simply-2026a10003d7?ecd=mkm_ret_260213_mscpmrk-OUS_ICYMI_etid8093905&uac=148436CN&impID=8093905 Medscape Europe Published February 03, 2026 Updated February 09, 2026 Weight Loss in Older Adults: Can More Protein Protect Bones? Weight Loss in Older Adults: Can More Protein Protect Bones? Edited by Archita Rai https://www.medscape.com/viewarticle/weight-loss-older-adults-can-more-protein-protect-bones-2026a10003ne?ecd=mkm_ret_260213_mscpmrk-OUS_ICYMI_etid8093905&uac=148436CN&impID=8093905 February 05, 2026 COMMENTARY High Ultra-Processed Food Intake Linked to Lung Cancer Risk High Ultra-Processed Food Intake Linked to Lung Cancer Risk Maurie Markman, MD https://www.medscape.com/viewarticle/high-ultra-processed-food-intake-linked-lung-cancer-risk-2026a10000tn?ecd=mkm_ret_260213_mscpmrk-OUS_ICYMI_etid8093905&uac=148436CN&impID=8093905 February 05, 2026 Does Caffeinated Coffee Trigger Atrial Fibrillation? Does Caffeinated Coffee Trigger Atrial Fibrillation? Ahmed El Shaer, MBBS; Douglas S. Paauw, MD https://www.medscape.com/viewarticle/does-caffeinated-coffee-trigger-atrial-fibrillation-2026a100022c?ecd=mkm_ret_260213_mscpmrk-OUS_ICYMI_etid8093905&uac=148436CN&impID=8093905 February 04, 2026 GERD vs NERD: Update Your Approach to Reflux Disease GERD vs NERD: Update Your Approach to Reflux Disease Matthew F. Watto, MD; Paul N. Williams, MD https://www.medscape.com/viewarticle/gerd-vs-nerd-update-your-approach-reflux-disease-2026a100033l?ecd=mkm_ret_260213_mscpmrk-OUS_ICYMI_etid8093905&uac=148436CN&impID=8093905 February 05, 2026

jueves, 12 de febrero de 2026

Merck is urged by patient groups to ensure widespread access to an HIV prevention pill being tested A late-stage study is not expected to be over until next year, but advocates want a commitment now

https://www.statnews.com/pharmalot/2026/02/11/merck-aids-hiv-access-gilead-pricing/ By Ed SilvermanFeb. 11, 2026 Pharmalot Columnist, Senior Writer

Drug injection fades as smoking grows more common, marking sea change in U.S. fentanyl epidemic Harm reduction experts applaud shift as safer, even as some officials reject pipe use

https://www.statnews.com/2026/02/12/fentanyl-harm-reduction-smoking-not-injecting/ By Lev FacherFeb. 12, 2026 Addiction Reporter

Maui Derm Hawaii 2026 - Maui Derm Hawaii 2026 January 25 - 29 | Maui, Hawaii - 90% Satisfied with Combo Therapy in Psoriatic Disease ++++

https://www.medscape.com/c25/p14/maui-derm-hawaii-2026-2026a100012f?ecd=WNL_conf_derm_maui-derm-spon_260212_MSCPEDIT_etid8096210&uac=148436CN&impID=8096210 Biologic Plus GLP-1 Agonist Improves Quality of Life in Psoriatic Disease Ted Bosworth https://www.medscape.com/viewarticle/biologic-plus-glp-1-agonist-improves-quality-life-psoriatic-2026a10002s0?ecd=WNL_conf_derm_maui-derm-spon_260212_MSCPEDIT_etid8096210&uac=148436CN&impID=8096210 January 28, 2026 Targeted Therapies Create Urgency for Early Diagnosis of Pemphigus and Pemphigoid Ted Bosworth https://www.medscape.com/viewarticle/targeted-therapies-create-urgency-early-diagnosis-pemphigus-2026a100037a?ecd=WNL_conf_derm_maui-derm-spon_260212_MSCPEDIT_etid8096210&uac=148436CN&impID=8096210 February 02, 2026 Expert Algorithm Offered to Optimize Treatment Success in Lichen Planopilaris Ted Bosworth https://www.medscape.com/viewarticle/expert-algorithm-offered-optimize-treatment-success-lichen-2026a10002z1?ecd=WNL_conf_derm_maui-derm-spon_260212_MSCPEDIT_etid8096210&uac=148436CN&impID=8096210 January 30, 2026 Phase 3 Trials Promise Better Options to Shut Down Connective Tissue Diseases Ted Bosworth https://www.medscape.com/viewarticle/phase-3-trials-promise-better-options-shut-down-connective-2026a10002mg?ecd=WNL_conf_derm_maui-derm-spon_260212_MSCPEDIT_etid8096210&uac=148436CN&impID=8096210 January 27, 2026

FDA Approves First-of-Its-Kind Device to Treat Pancreatic Cancer Device Delivers Non-invasive Therapy and Supports Care at Home

https://www.fda.gov/news-events/press-announcements/fda-approves-first-its-kind-device-treat-pancreatic-cancer?utm_medium=email&utm_source=govdelivery

Rare Disease Week: Genotypes and phenotypes in cholestasis

https://events.teams.microsoft.com/event/702ecd4d-b678-49b3-9fa1-da22861ca71d@37c354b2-85b0-47f5-b222-07b48d774ee3 Rare Disease Day Educational Sessions The NHS South East Genomic Medicine Service will be hosting four sessions to help colleagues learn and explore a range of rare genetic conditions. In the first session, Professor Richard Thompson (King's College London) will share his perspectives on the power of genomic medicine. The next few sessions will each explore patient and parent experiences of a rare disease diagnosis - sign up to hear Charlotte's, Maisie's and Diana's stories, from uncertainty of diagnosis during pregnancy, to the impacts of gene therapy. Join the sessions daily from 23 February at 12pm (UTC time).

No One Rides Alone - World Premiere - Gent, Belgium Share Sat, 28 Feb, 7pm - 10pm CEST

https://events.humanitix.com/no-one-rides-alone-premiere Watch "No One Rides Alone" at its Global Premiere Can someone with Multifocal Motor Neuropathy (MMN) ride the route of the Tour de France? That's what Clive Phillips and a team of fellow veterans set out to discover during the Tour de MMN 2025. "No One Rides Alone" follows the team as they ride along the 1955 Tour de France route, in the wheel tracks of the first British Tour de France team. It follows them as they push their limits, connect with others in the rare disease community, learn more about MMN and come face to face with the impacts of it and conditions like it. Join members of the team and double Paralympic champion Ben Watson on 28 February for the global premiere of the film, taking place in Gent, Belgium, and featuring a Q&A session after the screening. The film will also touring UK cinemas in March. No One Rides Alone https://makingthemostofnow.co.nz/no-one-rides-alone/

International advocacy for rare diseases

https://openacademy.eurordis.org/courses/international-advocacy-for-rare-diseases/ Learn with the Open Academy The EURORDIS Open Academy accompanies patient advocates by offering rare disease-specific comprehensive training programmes that empower advocates with the knowledge, skills and confidence they need to engage with different stakeholders as equal partners. Our Schools, supported by ERDERA, offer a blended learning approach that includes e-learning courses, webinars, in-person training, as well as research visits and networking opportunities. Increase your knowledge and skills in the rare disease space https://openacademy.eurordis.org/

The Remarkable Life of Ibelin to Receive EURORDIS Black Pearl Media and Awareness Raising Award 22 January 2026 +++

https://rarerevolutionmagazine.com/the-remarkable-life-of-ibelin-to-receive-eurordis-black-pearl-media-and-awareness-raising-award/ RARE Revolution Magazine recently covered our announcement that the 2026 EURORDIS Media & Awareness Raising Award will be presented to the Norwegian documentary The Remarkable Life of Ibelin at the EURORDIS Black Pearl Awards on 24 February. The film tells the story of Mats Steen, a young man living with Duchenne muscular dystrophy who found friendship, purpose and community through his World of Warcraft avatar. Our Acting CEO, Virginie Hivert, is quoted in the article reflecting on the documentary’s impact. EURORDIS Black Pearl Awards https://www.eurordis.org/black-pearl-awards/ The Remarkable Life of Ibelin | Official Trailer | Netflix https://www.youtube.com/watch?v=lM_hkJ0Rl-c

Podcast: Rare on Air

https://www.eurordis.org/rare-on-air/ Rare Disease Day bonus series Get ready for Rare Disease Day by tuning into our Rare on Air Stories bonus series, in which we read the stories of people impacted by rare diseases from across the globe. In the latest episode, we hear the story of Léon, who lives with LAMA2-related congenital muscular dystrophy. His mother Hong-Ahh shares her early search for answers and the ongoing efforts to support Léon through physiotherapy and respiratory care. You can also hear Jessa's story, which offers a look into how she has achieved remarkable milestones despite the challenges of chronic illness. 28 February is Rare Disease Day Raising awareness and generating change for the 300 million people worldwide living with a rare disease, their families and carers. https://www.rarediseaseday.org/

 “Rare Diseases in a Changing & Competitive Europe: Shaping policies to address the unmet needs of people living with rare diseases”. 

https://www.rare-diseases.eu/ ECRD 2026 posters Our European Conference on Rare Diseases and Orphan Products 2026 is inviting poster abstract submissions. Researchers, clinicians, advocates and experts are encouraged to share work on therapies development and access, diagnosis and prevention, highly specialised care, mental wellbeing, health technology assessment, the social sciences and humanities, and open-topic proposals. Submit your poster abstract by 6 March.

Fostering European political unity for cancer and rare diseases ++

https://www.intergrouponcancerandrarediseases.eu/ EU Budget Last week, members of the European Parliament's Intergroup on Cancer and Rare Diseases came together to reaffirm the need for a stronger and more explicit commitment to cancer and rare diseases in the 2028-34 Multiannual Financial Framework (MFF). Rosa Castro highlighted that "we, as a health community should come together to advocate for all decision makers to ensure that health remains as a key priority in the next EU budget cycle". Read our full The EU’s 2028-34 budget: Improving the multiannual financial framework for people living with a rare disease November 2025 In July 2025, the European Commission presented its proposal for the EU Multiannual Financial Framework (MFF) 2028–2034, setting out a budget of nearly €2 trillion to guide the Union’s spending priorities over the next seven years. https://www.eurordis.org/improving-multiannual-financial-framework/

Meet our 2026 Regional Representatives! Raising Youth Voices +++

https://www.rarediseaseday.org/raising-youth-voices/ Raising Youth Voices Last week’s Raising Youth Voices event, held in Barcelona as part of the Rare Disease Day 2026 campaign, brought together young rare disease advocates from every continent. They shared their personal experiences and highlighted the initiatives they are leading to drive change for people living with rare diseases. You can watch the full panel discussion online. A short film from the day, produced by Fondation Ipsen, will be released soon – stay tuned! Raising Youth Voices 2026 https://www.youtube.com/live/G9HKPZLKkKk We shed light on rare diseases to accelerate diagnosis https://www.fondation-ipsen.org/

THE GLOBAL ALLIANCE OF PERSONS LIVING WITH A RARE DISEASE +++

https://www.rarediseasesinternational.org/ European Blueprint EURORDIS and Rare Diseases International (RDI) are inviting patient organisations, advocates, and other stakeholders from across the WHO European Region to join our European Regional Task Force on Rare Diseases. This group will gather evidence, experience, and expertise to help shape our development of a European Blueprint for Rare Diseases, to be launched at our European Conference on Rare Diseases and Orphan Products (ECRD 2026). Apply now! Developing a European Blueprint for Rare Diseases: How this work will unfold February 2026 EURORDIS-Rare Diseases Europe is leading a multi-stakeholder initiative to develop a European Blueprint for Rare Diseases – a detailed design for how rare disease policy can be structured, coordinated, and delivered in practice. https://www.eurordis.org/blueprint-for-rare-diseases-coordinating-action-across-europe/ European Regional Task Force on Rare Diseases – Expression of Interest Rare Diseases Europe (EURORDIS), in collaboration with Rare Diseases International (RDI), is establishing the European Regional Task Force on Rare Diseases to bring together stakeholders from across the WHO European Region. https://forms.office.com/pages/responsepage.aspx?id=uv_BBwRMtkK5WUPa44YsSg_8cYkfEgFJkfThrO_639NUQTQ4SkUyNDFSQ1FCM0g2OE5FU0pZT05IOC4u&route=shorturl

Rare Disease Day 2026: More Than You Can Imagine February 2026

https://www.eurordis.org/rare-disease-day-2026-more-than-you-can-imagine/ On 28 February 2026, people across the globe will once again come together to mark Rare Disease Day. Coordinated by EURORDIS–Rare Diseases Europe and powered by a growing network of National Alliance partners, patient organisations, families and advocates it is a day built from local action and global solidarity, and it continues to expand year after year.

A Call to Action: Addressing the Burden of RSV in Adults Through Prevention With Vaccines Authors: Peter Openshaw, CBE, PhD, FRCP, FMedSci; Ann R. Falsey, MD

https://www.medscape.org/viewarticle/call-action-addressing-burden-rsv-adults-through-prevention-2025a1000x9g?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260211-OUS-HONC-call-action-addressing-burden-rsv-adults-through-prevention-2025a1000x9g-cta

Precision in Practice: Rethinking BRAF-Mutated Advanced NSCLC With Data and Experience Authors: Solange Peters, MD, PhD; Umberto Malapelle, PhD; Ernest Nadal, MD, PhD

https://www.medscape.org/viewarticle/precision-practice-rethinking-braf-mutated-advanced-nsclc-2025a1000wmw?page=2&sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_260211-12109743_ES_HONC#transcript-download-es

Conference Insights: Breaking Developments in ALK-Positive NSCLC and ES-SCLC Authors: Solange Peters, MD, PhD; Shirish M. Gadgeel, MD; Rafal Dziadziuszko, MD, PhD

https://www.medscape.org/viewarticle/conference-insights-breaking-developments-alk-positive-nsclc-2025a1000vwn?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260211-OUS-HONC-conference-insights-breaking-developments-alk-positive-nsclc-2025a1000vwn-cta

Shared Decision-Making in Epilepsy Today Authors: Bettina Schmitz, MD, PhD; Jakob Christensen, MD, PhD; Elinor Ben-Menachem, MD, PhD; Antonio Gil-Nagel, MD, PhD

https://www.medscape.org/viewarticle/1002600_sidebar9?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_260212-ES_LANG-NEUR-1002600-cta

Highlights from the Annual Neurosurgical Conference: New Standards in Diffuse Lower-Grade Glioma Authors: Mitchel S. Berger, MD; Macarena de la Fuente, MD; Michael Lim, MD

https://www.medscape.org/viewarticle/1002598_sidebar11?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_260212-ES_LANG-HONC-1002598-cta

Rapid Review Quiz: Substance Use Disorders Reviewed by Heidi Moawad, MD January 29, 2026 ++++

https://reference.medscape.com/viewarticle/rapid-review-quiz-drug-abuse-2026a10001w6?ecd=WNL_rrq_260212_MSCPEDIT_etid8096465&uac=148436CN&impID=8096465 Rapid Review Quiz: Marijuana Use Health Risks Heidi Moawad, MD https://reference.medscape.com/viewarticle/rapid-review-quiz-marijuana-use-health-risks-2025a1000lt3?ecd=WNL_rrq_260212_MSCPEDIT_etid8096465&uac=148436CN&impID=8096465 August 20, 2025 Rapid Rx Quiz: Opioid Overdose Mary L. Windle, PharmD https://reference.medscape.com/viewarticle/rapid-rx-quiz-opioid-overdose-2025a1000d2q?ecd=WNL_rrq_260212_MSCPEDIT_etid8096465&uac=148436CN&impID=8096465 July 17, 2025 Rapid Rx Quiz: Benzodiazepines Reviewed by Mary L. Windle, PharmD https://reference.medscape.com/viewarticle/rapid-rx-quiz-benzodiazepines-2025a1000wen?ecd=WNL_rrq_260212_MSCPEDIT_etid8096465&uac=148436CN&impID=8096465 December 08, 2025

miércoles, 11 de febrero de 2026

Routine aspirin therapy associated with lower rate of developing severe preeclampsia

https://www.news-medical.net/news/20260211/Routine-aspirin-therapy-associated-with-lower-rate-of-developing-severe-preeclampsia.aspx

Lessons in living with a rare disease: what living rare has taught me Written by Bailey Hunter

https://rarerevolutionmagazine.com/lessons-in-living-with-a-rare-disease-what-living-rare-has-taught-me/ Bailey Hunter shares her personal insights of living a rare life, teaching her resilience, solidarity, advocacy and to live life fully Living with a rare disease teaches you lessons you never asked to learn. It changes how you move through the world. It teaches patience in waiting rooms, courage in conversations you never expected to have and resilience in moments when your body does not cooperate. Over time, rare becomes less of a label and more of a lens that shapes how you see yourself, relationships and what truly matters. What I have learned is that rare not only describes a medical condition. It describes a way of living with more intention, more awareness and more strength than you knew you had. Rare teaches you to listen to your body, to advocate for what you need and to find community in places you never imagined. These lessons are shaped by setbacks, small victories and the quiet determination to keep going.

Visuomotor processing in the superior colliculus Elí Lezama [1] , Mario Treviño* [1]

https://www.academia.edu/academia-neuroscience-and-brain-research/1/2/10.20935/AcadNeurosci8046 The superior colliculus (SC) is an evolutionarily conserved midbrain structure that maintains a consistent laminar organization across most mammalian species. This architecture reflects shared functional requirements for visual processing, attentional control, and motor coordination. Physiological studies confirm that the SC can process visual information independently of the primary visual cortex (V1), sustaining visuomotor behaviors through subcortical networks following V1 lesion or inactivation. This capacity illustrates how alternative neural pathways can maintain essential survival-related functions without cortical involvement. Comparative approaches reveal both conserved operational principles and species-specific adaptations. In rodents, SC activity guides attentional allocation, perceptual selection, and adaptive decision-making based on visual cues. In primates, its extensive connectivity with cortical and subcortical structures supports target selection, saccade generation, and sensorimotor integration. Collectively, these findings establish the SC as a fundamental substrate for adaptive signal processing that links perception with action across diverse behavioral contexts. This review synthesizes current understanding of the mammalian SC, focusing on its roles in visual processing, attention, and motor coordination. By synthesizing evidence across species, we describe how conserved neural architecture contributes to adaptive perception and behavior, and how the SC complements cortical pathways in shaping visually guided actions. The launch of Academia Neuroscience and Brain Research Roberto Ciccocioppo Volume 1, Issue 1 https://www.academia.edu/journals/academia-neuroscience-and-brain-research/articles?source=journal-top-nav

Cognitive speed training over weeks may delay the diagnosis of dementia over decades

Cognitive speed training over weeks may delay the diagnosis of dementia over decades NIH-funded effort finds positive outcomes with strategies that engaged mostly unconscious, rather than conscious, thinking. https://www.nih.gov/news-events/news-releases/cognitive-speed-training-over-weeks-may-delay-diagnosis-dementia-over-decades A National Institutes of Health (NIH)-funded study that followed adults age 65 and older over 20 years has linked a specific cognitive training regimen to reduced diagnoses of Alzheimer disease and related dementias (ADRD). While the authors assessed three different kinds of training, only one, which challenged participants with rapid object detection tasks, was associated with a 25% lower rate of dementia diagnosis, as indicated by Medicare claims data.

A Call to Action: Addressing the Burden of RSV in Adults Through Prevention With Vaccines Authors: Peter Openshaw, CBE, PhD, FRCP, FMedSci; Ann R. Falsey, MD

https://www.medscape.org/viewarticle/call-action-addressing-burden-rsv-adults-through-prevention-2025a1000x9g?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260210-OUS-HONC-call-action-addressing-burden-rsv-adults-through-prevention-2025a1000x9g-cta

FDA approves pembrolizumab with paclitaxel for platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal carcinoma

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-pembrolizumab-paclitaxel-platinum-resistant-epithelial-ovarian-fallopian-tube-or?utm_medium=email&utm_source=govdelivery

NSCLC Survival and Immunochemotherapy: Does Timing Matter? Megan Brooks February 10, 2026

https://www.medscape.com/viewarticle/nsclc-survival-and-immunochemotherapy-does-timing-matter-2026a100044y

GLP-1s Plus Progestins Tied to Lower Endometrial Cancer Risk Edited by Gargi Mukherjee February 11, 2026

https://www.medscape.com/viewarticle/glp-1s-plus-progestins-tied-lower-endometrial-cancer-risk-2026a10004b9

Lipid Metabolism Is a Target in High-Risk Medulloblastoma Serge Cannasse Medscape Europe February 11, 2026

https://www.medscape.com/viewarticle/lipid-metabolism-target-high-risk-medulloblastoma-2026a10004b8

Prostate Radiotherapy Linked to High Rate of Late Urinary Toxicities Edited by Victoria Stern February 11, 2026

https://www.medscape.com/viewarticle/prostate-radiotherapy-linked-high-rate-late-urinary-2026a10004cm

NICE Backs Perioperative Immunotherapy for Bladder Cancer Edited by Zeel Mehta Medscape UK February 11, 2026

https://www.medscape.com/viewarticle/nice-backs-perioperative-immunotherapy-bladder-cancer-2026a10004cd

Case 6: De-Differentiated Endometrial Cancer e-Tumor Board Case Discussions are developed independently. ++

https://www.medscape.com/etumor/endometrial-cancer-s01/e06 Case 5: Multiply Recurrent Stage II Endometrial Cancer e-Tumor Board Case Discussions are developed independently. https://www.medscape.com/etumor/endometrial-cancer-s01/e05

Spontaneous Bruising and Vaginal Bleeding in a Middle-Aged Woman Belén Morales Franco, MD February 09, 2026

https://reference.medscape.com/viewarticle/spontaneous-bruising-and-vaginal-bleeding-middle-aged-woman-2026a10003md?ecd=wnl_edit_tpal_etid8095525&uac=148436CN&impID=8095525

Cardiometabolic Control Eludes Many Adults With Hypertension Lara Salahi February 10, 2026

https://www.medscape.com/viewarticle/cardiometabolic-control-eludes-many-adults-hypertension-2026a1000442?ecd=wnl_edit_tpal_etid8095525&uac=148436CN&impID=8095525

Sensory nerves play role in bone fracture healing

Sensory nerves play role in bone fracture healing At a Glance A study in mice found that after a bone fracture, the nerves that sense pain also promote healing by signaling for bone repair and wound healing. The findings could lead to new treatments that stimulate bone repair and might be used to drive bone formation in bone disorders such as osteoporosis. https://www.nih.gov/news-events/nih-research-matters/sensory-nerves-play-role-bone-fracture-healing

Understanding obesity-induced inflammation

Understanding obesity-induced inflammation At a Glance NIH-funded researchers detailed a chain of events through which obesity promotes harmful inflammation. The findings point to potential new pathways for treating obesity-related illnesses. https://www.nih.gov/news-events/nih-research-matters/understanding-obesity-induced-inflammation

People with dementia prescribed risky drugs

People with dementia prescribed risky drugs At a Glance Researchers found that many older adults with dementia were prescribed medications that can increase the risk of confusion, falls, and hospitalization. Reducing such unnecessary prescriptions could improve the quality of care for older adults. https://www.nih.gov/news-events/nih-research-matters/people-dementia-prescribed-risky-drugs

NIH scientists develop "digital twin" of eye cells to understand and treat age-related macular degeneration

NIH scientists develop "digital twin" of eye cells to understand and treat age-related macular degeneration Breakthrough modeling technology reveals how cells lose their organization in leading cause of vision loss. https://www.nih.gov/news-events/news-releases/nih-scientists-develop-digital-twin-eye-cells-understand-treat-age-related-macular-degeneration : A digital 3D image showing a polarized iRPE cell. It is very colorful with the cell border in magenta, the nuclei in cyan and the mitochondria in yellow. Representative image of a polarized iRPE cell. Phalloidin staining shows cell borders (magenta), Hoechst labels nuclei (cyan), while TOMM20 tagged with mEGFP was used to visualize mitochondria (yellow). National Institutes of Health (NIH) researchers have developed a digital replica of crucial eye cells, providing a new tool for studying how the cells organize themselves when they are healthy and affected by diseases. The platform opens a new door for therapeutic discovery for blinding diseases such as age-related macular degeneration (AMD), a leading cause of vision loss in people over 50.

Beyond the Infusion Chair: Expanding the Repertoire With Subcutaneous Immunotherapy in Cancer Care Authors: Laurence Albiges, MD, PhD; Maria T. Bourlon, MD, MS; Antonella Cardone

https://www.medscape.org/viewarticle/beyond-infusion-chair-expanding-repertoire-subcutaneous-2025a1000y59?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_cust_mscpedu_260211-LATAM-HONC-beyond-infusion-chair-expanding-repertoire-subcutaneous-2025a1000y59-cta

The Lancet Summit: shaping the future of diabetes prevention Nov 30–Dec 2, 2026 | Sitges, Spain + ++... ++

The Lancet Summit: shaping the future of diabetes prevention Nov 30–Dec 2, 2026 | Sitges, Spain https://thelancetsummit.com/diabetes-prevention/index.html?utm_campaign=update-lanpub&utm_medium=email&_hsenc=p2ANqtz-9RHLVXOhfK9L3hTtEqNYmkH28N8s3Py3uMJTBdwib4o_8c5pihyepwexHbPuENxKVIvNrNo8nIhX6wd-br0tdow1qs7g&_hsmi=402955683&utm_content=402666425&utm_source=hs_email Abstracts invited for short talks and posters Submit by Jun 12, 2026 Commercialisation and care sufficiency: the privatisation of children's homes in England Benjamin Goodair, DPhila b.goodair@lse.ac.uk ∙ François Schoenberger, PhDb,c ∙ Anders Bach-Mortensen, DPhil https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00279-8/fulltext?dgcid=hubspot_update_feature_updatealerts_lanpub&utm_campaign=update-lanpub&utm_medium=email&_hsenc=p2ANqtz-_YG8ZT1eATJ00vI0qJIy7vbdSdBXpyiLzVPFkkTu8Uci_LF06rIyOZBKm0IFIJMV-rzZSLVWePomjDWGJvDlapqPuPBw&_hsmi=402955683&utm_content=402666425&utm_source=hs_email Editorial e69 Strengthening cardiovascular disease prevention in Europe The Lancet Public Health https://www.thelancet.com/journals/lanpub/issue/vol11no2/PIIS2468-2667(26)X2001-1 Uptake and performance of self-collection offered through primary care to all eligible participants in a national cervical screening programme in Australia: a retrospective cohort study Farhana Sultana, PhDa ∙ Megan Smith, PhDb ∙ Prof Marion Saville, MBChBc,d ∙ Prof Deborah Bateson, MB BSf ∙ Prof David Roder, DDScg ∙ Vivienne Milch, MHPolh,i ∙ et al. https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00304-4/fulltext?dgcid=hubspot_update_feature_updatealerts_lanpub&utm_campaign=update-lanpub&utm_medium=email&_hsenc=p2ANqtz-9mVLdOpUrtgrzT65IUdydEK2dotTCDkVO0htibpyTnIqWY--2xAZ4XGaciXYCXnzpANgpL8oFCgFJLc2bcQUulwcKxFw&_hsmi=402955683&utm_content=402666425&utm_source=hs_email The potential effect of a geographically focused intervention against tuberculosis in the USA: a simulation modelling study Mathilda Regan, PhDa mathildaregan@hsph.harvard.edu ∙ Hening Cui, MSa ∙ Nicole A Swartwood, MSPHa ∙ Yunfei Li, ScDa ∙ Suzanne M Marks, MPHb ∙ Terrika Barham, PhDc ∙ Awal Khan, PhDb ∙ Carla A Winston, PhDb ∙ Prof Ted Cohen, DPHd ∙ Prof C Robert Horsburgh, Jr, MDe ∙ Prof Joshua A Salomon, PhDf ∙ Nicolas A Menzies, PhDa https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00306-8/fulltext?dgcid=hubspot_update_feature_updatealerts_lanpub&utm_campaign=update-lanpub&utm_medium=email&_hsenc=p2ANqtz-8vho989B16Y0AkchQBtq93dgvsTVD8v39AcK1BZh2h8IrbADYIksli-g_PjNazYTsFooOG4D_XYD3p-zKhbWmJNCQt1Q&_hsmi=402955683&utm_content=402666425&utm_source=hs_email

martes, 10 de febrero de 2026

Parents report safety risks with children’s at-home medical devices

https://www.news-medical.net/news/20260210/Parents-report-safety-risks-with-childrene28099s-at-home-medical-devices.aspx

How the Menstrual Cycle Affects Appetite, Metabolism, and Nutrition

https://www.news-medical.net/health/How-the-Menstrual-Cycle-Affects-Appetite-Metabolism-and-Nutrition.aspx This article examines how hormonal fluctuations across the menstrual cycle influence appetite, energy intake, metabolism, and nutrient utilization. It evaluates the evidence for cycle-synchronized nutrition and emphasizes flexible, individualized dietary strategies over rigid phase-based rules.

Bioactive Peptides in Culinary Spices and Their Potential Health Benefits

https://www.news-medical.net/health/Bioactive-Peptides-in-Culinary-Spices-and-Their-Potential-Health-Benefits.aspx This article examines how culinary spices contain protein-derived bioactive peptides that emerge through processing and digestion, expanding functional food science beyond phytochemicals. Drawing on proteomic, biochemical, and extract-based evidence, it critically evaluates antioxidant, enzyme-inhibitory, and signaling-related activities while highlighting current limitations and research gaps.

Chrono-Cardiology and Chrononutrition: Integrating Circadian Biology Into Cardiometabolic Care

https://www.news-medical.net/health/Chrono-Cardiology-and-Chrononutrition-Integrating-Circadian-Biology-Into-Cardiometabolic-Care.aspx How, when you eat, not just what you eat, shapes circadian blood pressure rhythms, metabolic health, and the future of non-pharmacological cardiovascular prevention.

Football finals push devoted fans’ bodies into overdrive

https://www.news-medical.net/news/20260210/Football-finals-push-devoted-fanse28099-bodies-into-overdrive.aspx From rising stress the night before kick-off to heart-rate spikes that defy the odds, wearable data reveals how a historic cup final pushed devoted fans’ bodies into overdrive.

Measles is raging worldwide: are you at risk? Cases in fully vaccinated people are rare and usually mild, but are likely to become more common as exposure to the virus rises. By Mariana Lenharo

https://www.nature.com/articles/d41586-026-00367-5?utm_source=Live+Audience&utm_campaign=2254b32e40-nature-briefing-daily-20260209&utm_medium=email&utm_term=0_-33f35e09ea-50432164

Tumor-Like Masses, Abdominal Swelling, Pancreatic Involvement: Making Sense of IgG4-Related Disease, a Multiorgan Fibroinflammatory Condition Authors: Emanuel Della Torre, MD, PhD; J. Matthias Löhr, MD, PhD; John H. Stone, MD, MPH

https://www.medscape.org/viewarticle/1002730?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260207-OUS-HONC-1002730-cta

Long COVID in Context: A Closer Look at Post-Viral Syndrome and Management Approaches Authors: Ziyad Al-Aly, MD; Bin Cao, MD

https://www.medscape.org/viewarticle/1002795?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260208-OUS-HONC-1002795-cta

Assessing Conditioning Regimens for HSCT: Optimizing Patient Outcomes Authors: Mohamad Mohty, MD, PhD; Daniele Avenoso, MD, PhD; Simona Sica, MD, PhD; Sergio Giralt, MD, FACP, FASTCT

https://www.medscape.org/viewarticle/1003061?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260209-OUS-HONC-1003061-cta

FDA rejects Regenxbio’s rare-disease gene therapy Agency raised questions about the surrogate biomarker used to predict clinical benefit By Adam FeuersteinFeb. 9, 2026 Senior Writer, Biotech

https://www.statnews.com/2026/02/09/fda-rejects-regenxbio-rare-disease-gene-therapy/

FDA warned a Hims & Hers compounder after finding bugs and failing to report a serious side effect The FDA inspected MedisourceRx months after Hims & Hers acquired the compounder

https://www.statnews.com/pharmalot/2026/02/09/fda-inspection-warns-hims-compounder-bugs-wegovy/ By Ed SilvermanFeb. 9, 2026 Pharmalot Columnist, Senior Writer Lawsuit against Hims & Hers should be ‘wake-up call’ for compounders, Novo chief counsel says In interview, attorney for Danish drugmaker says compounding of Wegovy pill is a ‘tipping point’ https://www.statnews.com/pharmalot/2026/02/09/hims-novo-lawsuit-chief-counsel-interview/ By Elaine Chen and Ed SilvermanFeb. 9, 2026

Eczema drug from Nektar Therapeutics maintains skin responses in one-year study The results met and in some cases exceeded investor expectations

https://www.statnews.com/2026/02/10/nektar-therapeutics-rezpeg-eczema-drug-maintains-skin-response-study/ By Adam FeuersteinFeb. 10, 2026 Adam Feuerstein, a senior writer and biotech columnist, is the author of Adam’s Biotech Scorecard, a subscriber-only newsletter about the crossroads of drug development, business, Wall Street, and biotechnology.

The new childhood vaccine guidelines have a paid leave problem Countries with strong parental leave don’t have to worry about infants getting sick at day care

https://www.statnews.com/2026/02/10/rsv-vaccine-schedule-denmark-norway-paid-leave-day-care/ By Ariana HendrixFeb. 10, 2026 Hendrix is freelance writer and mother based in Oslo, Norway.

National Cancer Institute studying ivermectin’s ‘ability to kill cancer cells,’ alarming career scientists The NCI director didn’t cite new evidence that prompted the agency to look into it

https://www.statnews.com/2026/02/10/ivermectin-for-cancer-national-cancer-institute-preclinical-study/ By Rachana Pradhan | KFF Health NewsFeb. 10, 2026

Heavy menstrual bleeding: an overlooked global burden The Lancet Obstetrics, Gynaecology, & Women's Health ++... ++

Heavy menstrual bleeding: an overlooked global burden The Lancet Obstetrics, Gynaecology, & Women's Health https://www.thelancet.com/journals/lanogw/article/PIIS3050-5038(26)00024-5/fulltext?dgcid=raven_jbs_etoc_email Feb 2026 Volume 2Number 2e75-e166 https://www.thelancet.com/journals/lanogw/issue/vol2no2/PIIS3050-5038(26)X2001-5 The role of menopause hormone therapy in modulating tirzepatide-associated weight loss in postmenopausal women with overweight or obesity: a retrospective cohort study Regina Castaneda, MDa,b ∙ Dima Bechenati, MDc ∙ Elif Tama, MDd ∙ Rene Rivera Gutierrez, MDa,b ∙ Maria A Espinosa, MDb ∙ Jose Villamarin, MDb ∙ et al. https://www.thelancet.com/journals/lanogw/article/PIIS3050-5038(25)00145-1/abstract?dgcid=raven_jbs_etoc_feature_lanogw Lifestyle intervention versus usual care for improving cardiovascular risk profile in the first year after hypertensive disorders of pregnancy in Australia (Blood Pressure Postpartum): a randomised controlled trial Prof Amanda Henry, PhDa,b,c ahenry@georgeinstitute.org.au ∙ Lynne M Roberts, PhDb,d ∙ Damian P Kotevski, PhDe ∙ Clare Arnott, PhDa,f,g ∙ Amanda Beech, MBBSh ∙ Bronwyn K Brew, PhDe ∙ et al. https://www.thelancet.com/journals/lanogw/article/PIIS3050-5038(25)00148-7/abstract?dgcid=raven_jbs_etoc_feature_lanogw

A Clinician's Primer on Friedreich Ataxia Authors: Wolfgang Nachbauer, MD, PhD; Mathieu Anheim, MD, PhD; Martin Delatycki, MBBS, FRACP, PhD; Paola Giunti, MD, PhD; Francesco​ Saccà, MD, FAAN

https://www.medscape.org/viewarticle/clinicians-primer-friedreich-ataxia-2025a1000zuh?page=2&sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_260209-12140062-ES-NEUR#expert-commentary-es

Multiorgan Fibroinflammatory Challenges in Multidisciplinary Practice: What's Your Approach? Authors: Emma Culver, MD, PhD

https://www.medscape.org/viewarticle/multiorgan-fibroinflammatory-challenges-multidisciplinary-2025a1000npv?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260209-OUS-HONC-multiorgan-fibroinflammatory-challenges-multidisciplinary-2025a1000npv-cta

Comparable efficacy of counselling, equine-assisted learning and nature-based interventions in family support S. Kezia Sullivan* [1] , Ann Hemingway [1]

https://www.academia.edu/2997-9196/2/4/10.20935/MHealthWellB8071 This study presents findings from an analysis of the impact of three different intervention types referred to as part of the Supporting Families Program in England (SFP), which supports families experiencing multiple challenges, including domestic violence, children in need of help, and mental health challenges—many of which are considered Adverse Childhood Experiences (ACEs). The interventions include a talk-based program (n = 809), a 5-day equine-assisted learning program (n = 812) and a nature-based intervention within a care farm (n = 312). The data were flags triggering involvement with social services, collected by the local authority as part of their usual operations. The flags studied were domestic violence, child in need, and education flags, as well as the total number of flags per person within each family; these were collected prior to referral and at a 1-year follow up. Analyses found that all services significantly reduced the number of domestic violence and child-in-need flags as well as the total number of flags per family member at 1-year follow-up, indicating similar efficacy between services. Equine-assisted learning and nature-based interventions may therefore provide alternative support for clients finding talk-based programs either undesirable or ineffective. Effective alternatives are essential for delivering inclusive care to marginalised groups, improving client agency and dignity by delivering choice and improved outcomes within social services to support mental health. Effects of physical education classes on well-being of university students Takemune Fukuie, Koshiro Inoue, Akihiko Yamaguchi Volume 3, Issue 1 https://www.academia.edu/journals/academia-mental-health-and-well-being/articles?source=journal-top-nav

Editorial p115 The value of patient experience in multiple sclerosis research The Lancet Neurology +++ +...

Safety and efficacy of adjunct dexamethasone in adults with herpes simplex virus encephalitis in the UK (DexEnceph): a multicentre, observer-blind, randomised, phase 3, controlled trial Prof Tom Solomon, FMedSci, PhDa,b,c,d tsolomon@liverpool.ac.uk ∙ Cory Hooper, PhDd ∙ Ava Easton, PhDd,e ∙ Anna Rosala-Hallas, MScf ∙ Bethany Facer, MScg ∙ Perry Moore, PhDc ∙ et al. https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00454-5/fulltext?dgcid=hubspot_update_feature_updatealerts_laneur&utm_campaign=update-laneur&utm_medium=email&_hsenc=p2ANqtz-_85bna4Zv-aUxQG_omDj0I63RSdKdh3FtAsJMiYwdwpkNhg020Tb9sUSSiBL3Qr6zGLFOeUWkV7bcomaD74kBILTKwxg&_hsmi=402732960&utm_content=402692110&utm_source=hs_email Safety and efficacy of crenezumab in cognitively unimpaired carriers of the PSEN1Glu280Ala mutation at risk for autosomal-dominant Alzheimer's disease in Colombia (API ADAD Colombia Trial): a phase 2, randomised, double-blind, placebo-controlled trial Prof Pierre N Tariot, MDl,* pierre.tariot@bannerhealth.com ∙ Prof Francisco S Lopera, MDa,*,† ∙ Silvia Ríos-Romenets, MDa,* ∙ Kaycee M Sink, MDb,* ∙ Margarita Giraldo-Chica, MDa ∙ Natalia Acosta-Baena, MDa ∙ et al. https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00426-0/fulltext?dgcid=hubspot_update_feature_updatealerts_laneur&utm_campaign=update-laneur&utm_medium=email&_hsenc=p2ANqtz-_A7kQTVDo8trLnW7yhpWDpJcZptW4YUx4oAQocGmqdHZCOiurN12naohxgvYos7ogg2wm-0WyFSrlENfRNdpd-I2wTkw&_hsmi=402732960&utm_content=402692110&utm_source=hs_email Early blood pressure management in acute ischaemic stroke before and after reperfusion treatment Prof Lili Song, PhDa,b,c ∙ Yu Mao, MDa ∙ Prof Else Charlotte Sandset, PhDd,e ∙ Nyika D Kruyt, PhDf ∙ Paul J Nederkoorn, PhDg ∙ Xia Wang, PhDc ∙ et al. https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00378-3/abstract?utm_campaign=update-laneur&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_laneur&_hsenc=p2ANqtz--XZ1TeLyvOrQbjOPufjmGnfocwHqYjdbpWomddjAcWIpAM__xDR5mlfD0DguqVHu_ajaE-hvP9K_3ExFuK82rDdN8mUQ&_hsmi=402732960&utm_content=402692110&utm_source=hs_email Editorial p115 The value of patient experience in multiple sclerosis research The Lancet Neurology https://www.thelancet.com/journals/laneur/issue/vol25no2/PIIS1474-4422(26)X0002-3