jueves, 31 de agosto de 2023

Quizartinib Approval Adds New Treatment Option for AML, Including in Older Patients

https://www.cancer.gov/news-events/cancer-currents-blog/2023/fda-vanflyta-aml-flt3?cid=eb_govdel

Niraparib Tosylate Monohydrate and Abiraterone Acetate

https://www.cancer.gov/about-cancer/treatment/drugs/niraparib-tosylate-monohydrate-and-abiraterone-acetate?cid=eb_govdel

Assessing the Clinical Utility of Liquid Biopsies Across 5 Potential Indications From Therapy Selection to Population Screening: A Review

https://pubmed.ncbi.nlm.nih.gov/37639262/

Is Lipoprotein(a) Clinically Actionable with Today's Evidence? The Answer is Yes

https://pubmed.ncbi.nlm.nih.gov/37632608/

Social and physical predictors of mental health impact in adult women who have an FMR1 premutation

https://www.sciencedirect.com/science/article/pii/S2949774423008385

How learning the truth about chaos theory has helped me as an inpatient child psychologist By Sharmila B. MehtaAug. 30, 2023

https://www.statnews.com/2023/08/30/youth-mental-health-crisis-chaos-theory-child-psychology/?utm_campaign=morning_rounds&utm_medium=email&_hsmi=272277540&_hsenc=p2ANqtz-8Hw7ZlDZ2FYnKLjoU4e-CjKQz-owAcW9y5G1XODl2pkeZZRo0LfR7A_YkaDK990tFu4seA9bDgsnBOw0Mr_lt-J0D0CQ&utm_content=272277538&utm_source=hs_email

Emotional dry cleaning: A writer helps doctors share their stories — and their pain Isabella Cueto By Isabella Cueto

Emotional dry cleaning: A writer helps doctors share their stories — and their pain Isabella Cueto By Isabella Cueto https://www.statnews.com/2023/08/30/laurel-braitman-memoir-health-care-workers-writing-workshops/?utm_campaign=morning_rounds&utm_medium=email&_hsmi=272277540&_hsenc=p2ANqtz-8uf9xC3WAsM2vWm7CsajorBz1i6ErL_fQxZ8a2d0jjvQOe2sGfAwDRktIgzWMC8jr31gwmTOYus7wD8RW123HduT2s4A&utm_content=272277538&utm_source=hs_email

NIMH's 75th Anniversary Symposium–In-Person Registration Closing Soon

NIMH's 75th Anniversary Symposium–In-Person Registration Closing Soon In September, the National Institute of Mental Health (NIMH) is launching its yearlong 75th anniversary celebration with "The Evolution of Mental Health Research" symposium, highlighting key advances in mental health research. Event date: September 13, 2023 Time: 8:30 a.m.–5:30 p.m. ET Location: Natcher Conference Center on the NIH campus in Bethesda, MD. This symposium is free, and registration is required. In-person registration will close on September 5. https://www.nimh.nih.gov/news/events/the-evolution-of-mental-health-research

AMD Days 2023 APHL, 2023

AMD Days 2023 APHL, 2023 From the website: "CDC OAMD and APHL have co-sponsored AMD day, AMD 2-day, Virtual AMD-days, and now AMD days since 2016. This symposium began as an opportunity for OAMD funded CDC projects to be shared and presented. It has evolved to be an opportunity for state and local public health laboratories, CDC laboratories to present their work, network, and hear from leaders in the field. We are excited to bring back AMD-days! This event will be held September 12-14, 2023 at the CDC Roybal Campus in Atlanta, GA." https://www.aphl.org/programs/infectious_disease/Pages/AMD-Days.aspx

A machine learning classifier using 33 host immune response mRNAs accurately distinguishes viral and non-viral acute respiratory illnesses in nasal swab samples

https://pubmed.ncbi.nlm.nih.gov/37641125/

Realising the potential of gene therapies for rare and ultra-rare inherited diseases

https://pubmed.ncbi.nlm.nih.gov/37624746/

CDC Assesses Risk From BA.2.86, Highly Mutated COVID-19 Variant

https://jamanetwork.com/journals/jama/fullarticle/2809132

Neighborhood Disadvantage, African Genetic Ancestry, Cancer Subtype, and Mortality Among Breast Cancer Survivors

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808931?resultClick=1

Ki-67, 21-Gene Recurrence Score, Endocrine Resistance, and Survival in Patients With Breast Cancer

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808932?resultClick=1

Gut Microbiome in Patients With Early-Stage and Late-Stage Melanoma

https://jamanetwork.com/journals/jamadermatology/article-abstract/2808971?resultClick=1

miércoles, 30 de agosto de 2023

Ending stigma and discrimination in mental health

https://www.thelancet.com/commission/stigma-and-discrimination-in-mental-health

Inequality in Cancer Care for People with a Disability (BSL-interpreted)...

The Lancet Series on racism, xenophobia, discrimination, and health

Advancing equity, diversity, and inclusion (EDI) is a commitment to health for all. The Lancet Group believes science can be an instrument for positive social change, and that journals have an important part to play in challenging systems that do not benefit everyone everywhere. https://www.thelancet.com/equity-diversity-inclusion?dgcid=hubspot_update_feature_updatealerts_laneur&utm_campaign=update-laneur&utm_medium=email&_hsmi=272193224&_hsenc=p2ANqtz--Z4KSBmoIp1QQMY7pk3CtF3YDc8rPoFFkMc2t_nZBmSfkF8GgUUEk2kVlGFG7djk54lENwNLNRJT-EDOqz_IVpkvvNSA&utm_content=272134703&utm_source=hs_email

The Lancet Neurology in conversation with William Jagust on amyloid β and cognition

https://thelancetneurology.buzzsprout.com/1391383/13415017-william-jagust-on-amyloid-and-cognition?utm_campaign=update-laneur&utm_medium=email&_hsmi=272193224&_hsenc=p2ANqtz-_PIzd-FqOzFyxWvIQPuScXaPdJ7YhhNx-39ue1oRter2Cj5PfQ8vT8afsJ3xP-skR8psmfOvH0Q2iWf_l8fmD-Xb5Pig&utm_content=272134703&utm_source=hs_email

The complex pathway between amyloid β and cognition: implications for therapy

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00128-X/fulltext?dgcid=hubspot_update_feature_updatealerts_laneur&utm_campaign=update-laneur&utm_medium=email&_hsmi=272193224&_hsenc=p2ANqtz-8kFM8glLJN8wqI6D0rHsNggYMK92muWpAfy-JESSvCk-Az8oEpFjAPQmqwvZdzXzpQaYVRW3Afq_r_eIokyXhmtRMfeg&utm_content=272134703&utm_source=hs_email

Evaluation of the feasibility, diagnostic yield, and clinical utility of rapid genome sequencing in infantile epilepsy (Gene-STEPS): an international, multicentre, pilot cohort study

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00246-6/fulltext?dgcid=hubspot_update_feature_updatealerts_laneur&utm_campaign=update-laneur&utm_medium=email&_hsmi=272193224&_hsenc=p2ANqtz-_SpNbWNquD8j3mwxipou9tQk3hePQE4-bNA04oO6w_XTCL5bimORP3D7p9j9C9bjCrZUomFShjifIZ6No146QK27Bq8w&utm_content=272134703&utm_source=hs_email

The structured ambulatory post-stroke care program for outpatient aftercare in patients with ischaemic stroke in Germany (SANO): an open-label, cluster-randomised controlled trial

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00216-8/fulltext?dgcid=hubspot_update_feature_updatealerts_laneur&utm_campaign=update-laneur&utm_medium=email&_hsmi=272193224&_hsenc=p2ANqtz-9YCgL1r6v2j_Xdw5iU9F5LuSXY66pEPt1KvQyz-5uCalur0U8uWdgmJHtL7Z9Lj92C5SYCg4ZNY3OdCS-huynoBHIVmg&utm_content=272134703&utm_source=hs_email

Cancer Screening Overview (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/screening/hp-screening-overview-pdq?cid=eb_govdel#top

Sleep Disorders (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/side-effects/sleep-disorders-hp-pdq?cid=eb_govdel#top

Gastrointestinal Complications (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/side-effects/constipation/gi-complications-hp-pdq?cid=eb_govdel#top

Cognitive Impairment in Adults With Cancer (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/side-effects/memory/cognitive-impairment-hp-pdq?cid=eb_govdel#top

Neuroblastoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq?cid=eb_govdel#top

Late Effects of Treatment for Childhood Cancer (PDQ®)–Health Professional Version

https://www.cancer.gov/types/childhood-cancers/late-effects-hp-pdq?cid=eb_govdel#top

Ewing Sarcoma and Undifferentiated Small Round Cell Sarcomas of Bone and Soft Tissue Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/bone/hp/ewing-treatment-pdq?cid=eb_govdel#top

Complications, Graft-Versus-Host Disease, and Late Effects After Pediatric Hematopoietic Stem Cell Transplantation (PDQ®)–Health Professional Version

https://www.cancer.gov/types/childhood-cancers/hp-stem-cell-transplant/gvhd?cid=eb_govdel#top

Childhood Central Nervous System Germ Cell Tumors Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/brain/hp/child-cns-germ-cell-treatment-pdq?cid=eb_govdel#top

Primary Liver Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/liver/hp/adult-liver-treatment-pdq?cid=eb_govdel#top

martes, 29 de agosto de 2023

Depression, Stress Worsen Premenstrual Syndrome Severity Liz Scherer

https://www.univadis.com/viewarticle/depression-stress-worsen-premenstrual-syndrome-severity-2023a1000jpr-c04c43cb-23f0-4354-bb66-bebf6b2d25d5?uac=148436CN&ecd=mkm_ret_230827_unibom_BOMGLOBAL_5184961&utm_source=&utm_medium=email&utm_campaign=auto_ous_bestofmonth_medupdates&utm_content=5184961&utm_term=&sso=true

After First Mini-Stroke, Ischaemic Stroke Risk Is Higher for Years After

https://www.univadis.com/neurology?uac=148436CN&ecd=mkm_ret_230828_uni-OUS_SPECIAL_etid5184337&u=&utm_source=&utm_medium=email&utm_campaign=adhoc_ous_special-neuro_20230828_ann-amer&utm_content=5184337&utm_term=&sso=true

Europe Approves Aquipta (atogepant) for Migraine Prevention Deepa Varma

https://www.univadis.com/viewarticle/europe-approves-aquipta-migraine-prevention-2023a1000jd8?uac=148436CN&ecd=mkm_ret_230828_uni-OUS_SPECIAL_etid5184337&u=&utm_source=&utm_medium=email&utm_campaign=adhoc_ous_special-neuro_20230828_ann-amer&utm_content=5184337&utm_term=&sso=true

Engaging People with Low-Grade Glioma in Cancer Research

https://www.cancer.gov/news-events/cancer-currents-blog/2023/low-grade-glioma-optimum?cid=eb_govdel

An Engineered Adeno-Associated Virus Capsid Mediates Efficient Transduction of Pericytes and Smooth Muscle Cells of the Brain Vasculature

https://www.liebertpub.com/doi/10.1089/hum.2022.211?utm_campaign=HUM+PR+August+24+2023&utm_content=Click+here&utm_term=&utm_medium=email&utm_source=Adestra

Physicians Aren't Asking Enough Questions About Cannabis Use Sara Novak

https://www.medscape.com/viewarticle/995954?src=

Medicare Announces 10 Drugs Targeted for Price Cuts in 2026 Kerry Dooley Young

https://www.medscape.com/viewarticle/995951

Canadian Guidelines Call for Shots, Nasal Spray in Naloxone Kits Kerry Dooley Young

https://www.medscape.com/viewarticle/995937

NIAID-Supported Research is Advancing the Response to Surging Syphilis Rates

https://www.niaid.nih.gov/news-events/niaid-syphilis-research?utm_campaign=+57502051&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

Public Comment on Draft Recommendation Statement and Draft Evidence Review: Primary Care Interventions to Prevent Child Maltreatment

https://www.uspreventiveservicestaskforce.org/uspstf/public-comments-and-nominations/opportunity-for-public-comment The U.S. Preventive Services Task Force seeks comments on a draft recommendation statement and draft evidence review on primary care interventions to prevent child maltreatment. The Task Force is calling for more research on how to prevent child maltreatment before it occurs in children and adolescents who do not show signs or symptoms of abuse and neglect. The draft recommendation statement and draft evidence review are available for review and public comment from August 29, 2023 to September 25, 2023 here.

Beyond the brain: The gut microbiome and Alzheimer’s disease

https://www.nia.nih.gov/news/beyond-brain-gut-microbiome-and-alzheimers-disease?utm_source=nia-eblast&utm_medium=email&utm_campaign=alzgov-20230829

New Class of Compounds Rewires Cancer Cells to Self-Destruct

https://www.cancer.gov/news-events/cancer-currents-blog/2023/rewiring-cancer-cells-self-destruct?cid=eb_govdel

ADHD and Complementary Health Approaches

https://www.nccih.nih.gov/health/providers/digest/adhd-and-complementary-health-approaches?nav=govdcd

lunes, 28 de agosto de 2023

Could a breathalyzer detect cancer?

https://www.news-medical.net/health/Could-a-breathalyzer-detect-cancer.aspx

Removal of thymus in adults linked to increased death, cancer incidence

https://www.siicsalud.com/des/accesoabiertoes.php

Personal exposure to radiofrequency electromagnetic fields in various occupations in Spain and France

https://www.sciencedirect.com/science/article/pii/S0160412023004294

Phase angle as a marker of outcome in hospitalized pediatric patients. A systematic review of the evidence (GRADE) with meta-analysis

https://link.springer.com/article/10.1007/s11154-023-09817-1

Left Ventricular Systolic Dysfunction in Patients Diagnosed With Hypertrophic Cardiomyopathy During Childhood: Insights From the SHaRe Registry

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062517

ERS statement on protracted bacterial bronchitis in children

https://erj.ersjournals.com/content/50/2/1602139

ECLAPTE: Effective Closure of LAParoTomy in Emergency—2023 World Society of Emergency Surgery guidelines for the closure of laparotomy in emergency settings

https://wjes.biomedcentral.com/articles/10.1186/s13017-023-00511-w

FDA approves multiple generics of ADHD and BED treatment (lisdexamfetamine dimesylate)

FDA has approved several first generics of Vyvanse (lisdexamfetamine dimesylate) capsules and chewable tablets for attention-deficit/hyperactivity disorder (ADHD) in patients six years and older and moderate to severe binge-eating disorder (BED) in adults. See Vyvanse’s prescribing information for details on dosing. https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-multiple-generics-adhd-and-bed-treatment?utm_medium=email&utm_source=govdelivery

The Mechanoreceptive Ion Channel PIEZO2 Plays a Critical Role in Sexual Function

https://www.nccih.nih.gov/research/research-results/the-mechanoreceptive-ion-channel-piezo2-plays-a-critical-role-in-sexual-function?nav=govd

Treating and Dealing with ADHD

https://www.fda.gov/consumers/consumer-updates/treating-and-dealing-adhd?utm_medium=email&utm_source=govdelivery

NIH-funded study supports use of ECMO for critically ill patients with obesity

https://www.nih.gov/news-events/news-releases/nih-funded-study-supports-use-ecmo-critically-ill-patients-obesity

FDA D.I.S.C.O. Burst Edition: FDA approval of Lynparza (olaparib), with abiraterone and prednisone, for BRCA-mutated metastatic castration-resistant prostate cancer

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-disco-burst-edition-fda-approval-lynparza-olaparib-abiraterone-and-prednisone-brca-mutated?utm_medium=email&utm_source=govdelivery

FDA takes steps to decrease barriers for overdose reversal agents with Dr. Marta Sokolowska

https://www.fda.gov/drugs/news-events-human-drugs/fda-takes-steps-decrease-barriers-overdose-reversal-agents-dr-marta-sokolowska?utm_medium=email&utm_source=govdelivery

Drug Shortages with CDR Emily Thakur

https://www.fda.gov/drugs/news-events-human-drugs/drug-shortages-cdr-emily-thakur?utm_medium=email&utm_source=govdelivery

Generics-at-a-Glance with Dr. Sarah Ibrahim

https://www.fda.gov/drugs/news-events-human-drugs/generics-glance-dr-sarah-ibrahim?utm_medium=email&utm_source=govdelivery

NIH Study Examines Connections Between Drinking Water Quality and Increased Lung Infections in People with Cystic Fibrosis

https://www.niaid.nih.gov/news-events/nih-study-examines-connections-between-drinking-water-quality-and-increased-lung?utm_campaign=+57489639&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

CTE identified in brain donations from young amateur athletes

https://www.nih.gov/news-events/news-releases/cte-identified-brain-donations-young-amateur-athletes

Trial evaluates behavioral and psychological interventions to reduce cardiotoxic effects of breast cancer treatment

https://www.news-medical.net/news/20230828/Trial-evaluates-behavioral-and-psychological-interventions-to-reduce-cardiotoxic-effects-of-breast-cancer-treatment.aspx

General persistence of physical activity habits despite decline in participation during adolescence

https://www.news-medical.net/news/20230828/General-persistence-of-physical-activity-habits-despite-decline-in-participation-during-adolescence.aspx

Study confirms the anti-cancer effects of Kencur extract

https://www.news-medical.net/news/20230828/Study-confirms-the-anti-cancer-effects-of-Kencur-extract.aspx

First oral treatment for Lipoprotein(a) shows significant cholesterol reduction

https://www.news-medical.net/news/20230828/First-oral-treatment-for-Lipoprotein(a)-shows-significant-cholesterol-reduction.aspx

Physiology-guided complete revascularization reduces ischemic events in older MI patients

https://www.news-medical.net/news/20230828/Physiology-guided-complete-revascularization-reduces-ischemic-events-in-older-MI-patients.aspx

Can vitamins really fight cancer? New study uncovers surprising links between micronutrients and cancer risk

https://www.news-medical.net/news/20230827/Can-vitamins-really-fight-cancer-New-study-uncovers-surprising-links-between-micronutrients-and-cancer-risk.aspx

domingo, 27 de agosto de 2023

Role of the pioneer transcription factor GATA2 in health and disease. Aktar Amena, et al. Journal of molecular medicine (Berlin, Germany) 2023 0 0.

https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=rare&query=home

BNT162b2 Elicited an Efficient Cell-Mediated Response against SARS-CoV-2 in Kidney Transplant Recipients and Common Variable Immunodeficiency Patients. La Civita Evelina, et al. Viruses 2023 0 0. (8)

https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=pi&query=home

Rare variant and polygenic analyses of amyotrophic lateral sclerosis in the French-Canadian genome JP Ross et al, Genetics in Medicine, August 25, 2023

https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=nd&query=home

Risk Assessment Summary for SARS CoV-2 Sublineage BA.2.86 CDC, August 23, 2023

https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=Infectious%20diseases&query=home

Refining a multifaceted model of perceived utility of genomic sequencing results. Devan M Duenas et al. Public Health Genomics 2023 8

https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=cancer&query=home

Cost effectiveness review of text messaging, smartphone application, and website interventions targeting T2DM or hypertension. Ruben Willems et al. NPJ Digit Med 2023 8 (1) 150

https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=diabetes&query=home

Are You Up to Date on Your Preventive Care? CDC, July 2023

https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=fhh&query=home

Environmental and genetic predictors of human cardiovascular ageing Nature Comm, August 21, 2023

https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=HLBS&query=home

Thrombocytopenic, thromboembolic and haemorrhagic events following second dose with BNT162b2 and ChAdOx1: self-controlled case series analysis of the English national sentinel cohort

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00100-X/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-8SsTTmo7DznyS_il7m0izvPjEa90kGyMpQ3pimuf954jOJop-Dv6FdebzvuDo_0rMrbzO7SLIUeo08PgBr01QP8augCQ&utm_content=271743104&utm_source=hs_email

Humoral and cellular immune responses eleven months after the third dose of BNT162b2 an mRNA-based COVID-19 vaccine in people with HIV – a prospective observational cohort study

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00226-8/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-9XDKeMN-484aoBsM6lCaiwKhIzHn-8kQvYsk_9ZtT9qGmLIA1e2xM_xnzjPLmDF4QJWlreNXDXQjD9duo6IGD0sB_jMw&utm_content=271743104&utm_source=hs_email

Real-world assessment of immunogenicity in immunocompromised individuals following SARS-CoV-2 mRNA vaccination: a one-year follow-up of the prospective clinical trial COVAXID

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00265-7/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-9r-mrd0yoEGnp1oEBx-S39jYPfCnPFIPIbU8VPd-YGO13je8ebAz8zb9UQYYy_Z_8_WFx9xBu8OBVy4tFsIhmU1Zasrw&utm_content=271743104&utm_source=hs_email

Hippocampal subfield abnormalities and biomarkers of pathologic brain changes: from SARS-CoV-2 acute infection to post-COVID syndrome

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00276-1/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz--cJZuH0S2ItK7CO-xsYE0aDpJFA4RczCrwyHnNEK7MNrczHqf9tINpPDrqcYB3NnAWV8FbmHcYeidiKVjuun9yI5eWhA&utm_content=271743104&utm_source=hs_email

Humoral immune responses associated with control of SARS-CoV-2 breakthrough infections in a vaccinated US military population

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00248-7/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-_PPNgwZyIEYyU13WUGvLB_RdXbPR2x9Be7Uz0nW0KoL7EOyr2EZJf1uN5bE64fXwJ3E82TV55jcxJjNTHCH8JpBYsV1w&utm_content=271743104&utm_source=hs_email

Comparative subgenomic mRNA profiles of SARS-CoV-2 Alpha, Delta and Omicron BA.1, BA.2 and BA.5 sub-lineages using Danish COVID-19 genomic surveillance data

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00234-7/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-8RxUPrEF6aYxGbHHYVUpN9kvvcnAgL_0mX9Nf4KoYGFhj_zqMM-qpaVw2yvoWNJ__6n9MDd-Ai2mzg8XtJh2C8kbp-sw&utm_content=271743104&utm_source=hs_email

Clinical phenotypes and quality of life to define post-COVID-19 syndrome: a cluster analysis of the multinational, prospective ORCHESTRA cohort

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00284-5/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-_2-h8pwegWyeh_RdGTIDObNMY7gixiEtmUG8-Slzr_oZHOZ-OBXNZhTya9H1LvjAvfl8ubYNqZxjOFRRH3oSX_1cw6ug&utm_content=271743104&utm_source=hs_email

Safety and immunogenicity of a variant-adapted SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant as a booster in adults primed with authorized vaccines: a phase 3, parallel-group study

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00286-9/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-98Buezzd1BrWyxXaFdCs3yWjYoylSuc2tJ_C6EIiPmfNvbKXzUV3vz0fl-xOnNdbNKTggaO-nzDvMsCQP0UtC1kYU7YQ&utm_content=271743104&utm_source=hs_email

The effects of COVID-19 on cognitive performance in a community-based cohort: a COVID symptom study biobank prospective cohort study

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00263-8/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-99j8WxZGbRm5Q5TuqTRd0MdQLfpWxPF4JzvbxWkZ8gbrOlajZl39vZdJbZ9muPdSgs19j-olv4X2gWPYDC0p09bhR6wQ&utm_content=271743104&utm_source=hs_email

Saliva microbiome in relation to SARS-CoV-2 infection in a prospective cohort of healthy US adults

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00296-7/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-8DvEFzAk6gUrbtMmfY4cQA2K-O2lpEhGN8PPZF0cHUj9Khj3LgPdNcdsMljG51IMAJb70oo4qYy-QVAzlX0rHw2qJL9g&utm_content=271743104&utm_source=hs_email

Safety and immunogenicity of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted with AS03: A randomised, placebo-controlled, observer-blinded phase 1/2 trial

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00299-1/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-9WnwpNKFnhtn76gzNFIjaEg-D7kr0TvgIc9sZ1hM9r1I9Acdv8qrHhUm3VgAuhgvPaC-JQN_w_2ASqXCM3-f8nOl99Dg&utm_content=271743104&utm_source=hs_email

Prolonged indoleamine 2,3-dioxygenase-2 activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00294-3/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-9nj7aNxWzhzRLI90P8-pfD8g8BYxjuV3R2C-wPN14cFLFJBuIlEhEwVyKY23J8FKDXTyJKBc3lA-lsIP_66tOGts1eRA&utm_content=271743104&utm_source=hs_email

Clinical outcome and humoral immune responses of β-thalassemia major patients with severe iron overload to SARS-CoV-2 infection and vaccination: a prospective cohort study

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00273-0/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-8RCgZK5Pa2yyvRqU-T-s6pohlSMRor2vJqycFvl0LhJ0mRlA8YhbqLIYEN4EBrZhJ7TnjeXF37QLSdTySMLRBFZ4FyaQ&utm_content=271743104&utm_source=hs_email

Bosentan for high-risk outpatients with COVID-19 infection: a randomized, double blind, placebo-controlled trial

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00294-8/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-_o-0wihROd7WBiy7PxYNhHE3lmPARlcHygfMbqEJxGe-Ra4HWZ2Y3Mocx4L2IHDa1SCtTUe9Derxue0bfBhY_aaSaYCw&utm_content=271743104&utm_source=hs_email

Effects of previous infection, vaccination, and hybrid immunity against symptomatic Alpha, Beta, and Delta SARS-CoV-2 infections: an observational study

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00299-2/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz--FwVty6ygfadJEbwkrGF2_UDogR2OYmmkEHuy2GAX36-7KgJpT6rUq8HupPkqBhnyPKpYlftOHAOgPG8cBitfScFYw3g&utm_content=271743104&utm_source=hs_email

Mechanisms and clinical relevance of the bidirectional relationship of viral infections with metabolic diseases

https://www.thelancet.com/journals/landia/article/PIIS2213-8587(23)00154-7/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-_AnLGaNjcVogm_HmFcLZ8TiO8TUKFLXFE_9h9pLieDBM2q6-e2iCXPIY1VZW1vy0miqG-b3cOaTPyOQDbsHLZxBJHj7g&utm_content=271743104&utm_source=hs_email

Effect of COVID-19 vaccination and booster on maternal–fetal outcomes: a retrospective cohort study

https://www.thelancet.com/journals/landig/article/PIIS2589-7500(23)00093-6/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-_NXrlgTtKP3J97PADI0dc4p-vyDCWuLvTaUeggG_6zBzXiGMbu12lM6SfRr0qjScJdhCjWkT0dX3I_rqQKYk7lH7FfdQ&utm_content=271743104&utm_source=hs_email

Effectiveness of bivalent mRNA vaccines against medically attended symptomatic SARS-CoV-2 infection and COVID-19-related hospital admission among SARS-CoV-2-naive and previously infected individuals: a retrospective cohort study

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00373-0/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-_twCLkEHuieRKMOPnKJPRbed8-4YvOXcDVpApjQpWUs_lgev8d_AzZBts0joofcTtZgACvLXbdZMByUkHb3_2Me6fQJg&utm_content=271743104&utm_source=hs_email

Comparative antibody and cell-mediated immune responses, reactogenicity, and efficacy of homologous and heterologous boosting with CoronaVac and BNT162b2 (Cobovax): an open-label, randomised trial

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00216-1/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-9KRGiw0ihd1W9tcLKQ1Is4Ou-6LOFH22PZuD9guoSkmoFMwpmCw5itmcqZBvU6u-UGVd0cmgCBr23pQLcN12fUj0NRwA&utm_content=271743104&utm_source=hs_email

Dynamics of inflammatory responses after SARS-CoV-2 infection by vaccination status in the USA: a prospective cohort study

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00171-4/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-8vE3cwR9KjbgKeMRFe9ako1e2MJjBAVPCvEFQIAhVzgXlfnCiMBb3tY_7kEkXyo4bUMymfwhifxrHQ2xjRpYeV4S1AaA&utm_content=271743104&utm_source=hs_email

Risk of autoimmune diseases following COVID-19 and the potential protective effect from vaccination: a population-based cohort study

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00331-0/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-8xzZ1W5YF4CWKm_d2DzwFjIKHGML5Fj8SPHCxhXi_ePKRNExcb_GHl_xU51IX6MANmRS-vvQ5ZFfnJ94wwHbFX8RlONg&utm_content=271743104&utm_source=hs_email

The Lancet Oncology in conversation with Xuesong Han on cancer diagnosis during the COVID-19 pandemic in the USA

https://thelancetoncology.buzzsprout.com/1391338/13335683-xuesong-han-on-cancer-diagnosis-during-the-covid-19-pandemic-in-the-usa?utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-9-uwLMZsu4rNwyuiRbi7apRsZTh_m4VkG_0CcEZSuXOl7SZSkbY-KS4OR7ft_-1yOLu-oh3-N-Js0HJ7X_vXjgfm6qPw&utm_content=271743104&utm_source=hs_email

Safety and efficacy of inhaled IBIO123 for mild-to-moderate COVID-19: a randomised, double-blind, dose-ascending, placebo-controlled, phase 1/2 trial

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00393-6/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=271757280&_hsenc=p2ANqtz-_vfndUd6j-51UnfLag_wW2TmloKJGEtmQZHYqTw7bhpfdhT7xa4s9ZtLxXOgfWXR6qbzDCJAfjlc-65loG09LJwnwJFA&utm_content=271743104&utm_source=hs_email

The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action

https://www.thelancet.com/commission/sudden-cardiac-death?dgcid=hubspot_email_conferencealerts_lancetscd23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=271578212&_hsenc=p2ANqtz-_h65acqETUMmEBP6y__IUCcIMeQqTY9_d1dA5neViAnQJ-FK411BAy7sb6_QJrg0O15o4yYHxbokAgNMvy10vLsPX5bg&utm_content=271578212&utm_source=hs_email

Back to basics for out-of-hospital cardiac arrest

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01560-X/fulltext?dgcid=hubspot_email_conferencealerts_esc23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=271578212&_hsenc=p2ANqtz-_wz85Cm0pvAmJatEPSstkPtGCZjSarH4MncIHvP5nPxDQ948maAsYLspmgNkRRW2XFN7Pil-2na4FJOHcccVQaDkq-aA&utm_content=271578212&utm_source=hs_email

Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01351-X/fulltext?dgcid=hubspot_email_conferencealerts_esc23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=271578212&_hsenc=p2ANqtz-8pVvO1fUd3vvpGSmYavq_AMMWYtk9mlAoVBHtjnJmYNL69JFK0S7FPjv1p781NotsgffXFtXM92JgqbCC8y681aaS2SQ&utm_content=271578212&utm_source=hs_email

The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action

https://www.thelancet.com/commission/sudden-cardiac-death?dgcid=hubspot_email_conferencealerts_lancetscd23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=271578212&_hsenc=p2ANqtz-9vH__jJN3gEc4SSrJoMCXBW9hVv2OhgI4K-oJ1vwuzwK9dJtRpC-witf6Gop9zVPmBMNB3raRncuGK64V1YX0JCnjfmA&utm_content=271578212&utm_source=hs_email

sábado, 26 de agosto de 2023

ONE-TWO PUNCH TO DETECT AND WIPE OUT LUNG CANCER

One-Two Punch to Detect and Wipe Out Lung Cancer By Ivanhoe Broadcast News on August 16, 2023 https://www.ivanhoe.com/medical-breakthroughs/one-two-punch-to-detect-and-wipe-out-lung-cancer/

BATTLING OBESITY IN TEENS: GROUNDBREAKING GUIDELINES FOR CHILDREN

Battling Obesity in Teens: Groundbreaking Guidelines for Children By Ivanhoe Broadcast News on August 22, 2023 https://www.ivanhoe.com/medical-breakthroughs/battling-obesity-in-teens-groundbreaking-guidelines-for-children/

TOO MUCH EXERCISE: CAN IT HURT YOUR HEART?

Too Much Exercise: Can it Hurt Your Heart? By Ivanhoe Broadcast News on August 24, 2023 https://www.ivanhoe.com/medical-breakthroughs/too-much-exercise-can-it-hurt-your-heart/

TEENS AND SOCIAL MEDIA: NEW GUIDELINES FOR PARENTS

Teens and Social Media: New Guidelines for Parents By Ivanhoe Broadcast News on September 3, 2023 https://www.ivanhoe.com/?p=31174&preview=1&_ppp=ddfe27b033

MORE THAN MEDICINE: BEDSIDE MANNERS MATTER

More Than Medicine: Bedside Manners Matter By Ivanhoe Broadcast News on September 2, 2023 https://www.ivanhoe.com/?p=31171&preview=1&_ppp=66bdd57eb6

ANTIBIOTIC ALERT: REDUCING DRUG OVERUSE IN KIDS!

Antibiotic Alert: Reducing Drug Overuse in Kids By Ivanhoe Broadcast News on September 2, 2023 https://www.ivanhoe.com/?p=31168&preview=1&_ppp=5967e46f75

PEANUT PATCH: FIGHTING CHILDHOOD ALLERGIES

Peanut Patch: Fighting Childhood Allergies By Ivanhoe Broadcast News on August 28, 2023 https://www.ivanhoe.com/?p=31130&preview=1&_ppp=72463ccf86

9/11 FIRST RESPONDERS ARE STILL SAVING LIVES

9/11 First Responders Are Still Saving Lives By Ivanhoe Broadcast News on August 29, 2023 https://www.ivanhoe.com/?p=31137&preview=1&_ppp=cc6784d966

BREAKING BARRIERS: BARIATRIC SURGERY TO PREVENT CANCER

Bariatric Surgery to Prevent Cancer By Ivanhoe Broadcast News on August 30, 2023 https://www.ivanhoe.com/?p=31144&preview=1&_ppp=6fe245bc7f

ON THE MOVE: PORTABLE MRI FOR CHILDREN

Portable MRI for Children By Ivanhoe Broadcast News on August 31, 2023 https://www.ivanhoe.com/?p=31151&preview=1&_ppp=59fc7205f2

NURSING 911: HEALTHCARE STAFFING CRISIS

Nursing 911: Healthcare Staffing Crisis By Ivanhoe Broadcast News on September 1, 2023 https://www.ivanhoe.com/?p=31165&preview=1&_ppp=942d3b7cfc

The top 10 research priorities for pancreatitis: findings from a James Lind Alliance priority setting partnership

The top 10 research priorities for pancreatitis: findings from a James Lind Alliance priority setting partnership Sep 2023 Volume 8Number 9p771-860, e7 https://www.thelancet.com/journals/langas/issue/current

Unsilencing liver disease The Lancet Gastroenterology & Hepatology

Unsilencing liver disease The Lancet Gastroenterology & Hepatology Sep 2023 Volume 8Number 9p771-860, e7 https://www.thelancet.com/journals/langas/issue/current

The Lancet Gastroenterology & Hepatology in conversation with Marc Rothenberg on a trial of benralizumab in eosinophilic gastritis

https://thelancetgastrohep.buzzsprout.com/1728646/13383469-marc-rothenberg-on-a-trial-of-benralizumab-in-eosinophilic-gastritis?utm_campaign=update-langas&utm_medium=email&_hsmi=271628053&_hsenc=p2ANqtz--eHvhAOvYN8Ld6M6vvpGvzzZ3eJpEWJTmlaD10P0t8oq3tsMt6qhvNC-1-jlZ1vDE2pzPFZrcnkRd7nrq71SVnvgydFA&utm_content=271609654&utm_source=hs_email

Clinical application of circulating tumour DNA in colorectal cancer

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00146-2/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsmi=271628053&_hsenc=p2ANqtz-_vlrEoWdqNNSpU2Is8uukH1ktdZGdMQOzaNYAh1IwKKD_jtMim5EkvUCVsndMcfsz7uzoX3ltTI-yffRae7nEiWsffHg&utm_content=271609654&utm_source=hs_email

Type 2 diabetes, hepatic decompensation, and hepatocellular carcinoma in patients with non-alcoholic fatty liver disease: an individual participant-level data meta-analysis

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00157-7/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsmi=271628053&_hsenc=p2ANqtz--2lc7D1av0MW2W8hED4PAmA_-oN3kpuEVWlQz9xQhCGo4kBt93T4aLcF8Dsguci6Bz8YO2AFDxHlLLDnnauVYfHsHtxQ&utm_content=271609654&utm_source=hs_email

Benralizumab for eosinophilic gastritis: a single-site, randomised, double-blind, placebo-controlled, phase 2 trial

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00145-0/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsmi=271628053&_hsenc=p2ANqtz-9EHLEII79Dutg__4SsGHhTWP7--lb0JmwhmCV9gbXXD2NxN2dHHQRwHaaeqZG72YiLy0bACYy-JNvW3xHKb-r5MFuuqQ&utm_content=271609654&utm_source=hs_email

NIH study examines connections between drinking water quality and increased lung infections in people with cystic fibrosis

https://www.nih.gov/news-events/news-releases/nih-study-examines-connections-between-drinking-water-quality-increased-lung-infections-people-cystic-fibrosis

Transcriptional profiling of immune responses in NHPs after low-dose, VSV-based vaccination against Marburg virus

https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2252513?utm_campaign=+57462620&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

viernes, 25 de agosto de 2023

Diagnosis and Treatment of Tethered Spinal Cord

https://effectivehealthcare.ahrq.gov/products/tethered-spinal-cord/protocol This review will summarize the evidence regarding diagnosis, prophylactic treatment, symptomatic treatment, and repeat surgery of tethered spinal cord. With funding from PCORI, AHRQ commissioned this work to synthesize the findings on the diagnosis and treatment of tethered spinal cord. The systematic review will support the Congress for Neurological Surgeons clinical practice guidelines.

Treatment of Stage I-III Squamous Cell Anal Cancer

Treatment of Stage I-III Squamous Cell Anal Cancer: This is an new protocol for a systematic review that will summarize the state of the evidence on treatment of stage I-III squamous cell carcinoma of the anal canal and anal margin. This systematic review will assess the effectiveness and harms of treatment for stages I-III squamous cell anal cancer. This review, funded by the Patient-Centered Outcomes Research Institute, will be used by the American Society of Clinical Oncology and the American Society of Radiation Oncology to update clinical practice guidelines.

Diagnosis and Management of Obsessive Compulsive Disorders in Children

Diagnosis and Management of Obsessive Compulsive Disorders in Children: The systematic review will summarize the findings from 1. Studies related to the accuracy of assessment tools compared to reference standard methods to identify OCD in symptomatic youth and 2. Studies of psychological and/or pharmacological treatments of OCD. This comparative effectiveness review will inform a planned update of the 2012 American Academy of Child and Adolescent Psychiatry (AACAP) Practice Parameter. AACAP nominated this topic to the Patient-Centered Outcomes Research Institute, which contracted with the Agency for Healthcare Research and Quality to conduct the review. Specifically, the systematic review will summarize the findings from 1. Studies related to the accuracy of assessment tools compared to reference standard methods to identify OCD in symptomatic youth and 2. Studies of psychological and/or pharmacological treatments of OCD. The intended audience includes guideline developers, child psychiatrists and psychologists, pediatricians, family physicians, advanced practice providers, parents, and patients.

FDA Approves First Biosimilar to Treat Multiple Sclerosis Tyruko (natalizumab-sztn)

https://www.fda.gov/news-events/press-announcements/fda-approves-first-biosimilar-treat-multiple-sclerosis?utm_medium=email&utm_source=govdelivery

Immunogenicity of a Two Dose Regimen of Moderna mRNA Beta/Omicron BA.1 Bivalent Variant Vaccine Boost in a Randomized Clinical Trial

https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad323/7240453?login=false&utm_campaign=+57446363&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

NIAID-Funded Study Traces Evolution of Malaria Drug Resistance in E. Africa

https://www.niaid.nih.gov/news-events/artemisinin-partial-resistance?utm_campaign=+57447388&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

COVID-19 and Community Health Resources

https://www.niddk.nih.gov/health-information/healthy-moments/episodes/covid-19-community-health-resources?utm_medium=email&utm_source=govdelivery

The power of music

https://magazine.medlineplus.gov/article/the-power-of-music

Kristin Chenoweth wants to put migraine awareness center stage

https://magazine.medlineplus.gov/article/kristin-chenoweth-wants-to-put-migraine-awareness-center-stage

Starting the conversation to improve mental health

https://magazine.medlineplus.gov/article/starting-the-conversation-to-improve-mental-health

Meet the Director: Shannon N. Zenk, Ph.D., M.P.H., R.N., FAAN, National Institute of Nursing Research

https://magazine.medlineplus.gov/article/meet-the-director-shannon-n-zenk-ph.d-m.p.h-r.n-faan-national-institute-of-nursing-research

Meet the Director: Lindsey A. Criswell, M.D., M.P.H., D.Sc., National Institute of Arthritis and Musculoskeletal and Skin Diseases

https://magazine.medlineplus.gov/article/meet-the-director-lindsey-a-criswell-m.d-m.p.h-d.sc

Meet the Director: Debara L. Tucci, M.D., M.S., M.B.A., National Institute on Deafness and Other Communication Disorders

https://magazine.medlineplus.gov/article/meet-the-director-debara-l-tucci-m.d-m.s-m.b.a-national-institute-on-deafness-and-other-communication-disorders?utm_medium=email&utm_source=govdelivery

jueves, 24 de agosto de 2023

The Start-to-Finish of Orphan Drugs From regulation & policy to global pricing to gene therapies

https://www.terrapinn.com/conference/world-orphan-drug-congress/index.stm 30 October 2023 | Pre-Congress Workshops (InterContinental Barcelona - next to Fira de Barcelona) 31 October - 2 November 2023 | Main Congress Days (Fira de Barcelona Montjuic)

Training for patient representatives and advocates on leadership and communication skills 26 October 2023 - 09:00 Gdańsk, Poland

Training for patient representatives and advocates on leadership and communication skills EJP RD - European Joint Programme on Rare Diseases - Training for patient representatives and advocates on leadership and communication skills 26 October 2023 - 09:00 Gdańsk, Poland https://www.ejprarediseases.org/event/training-for-patient-representatives-and-advocates-on-leadership-and-communication-skills-2/

List of the marketing authorisations

https://www.eurordis.org/information-support/list-of-the-marketing-authorisations/

Fighting the Rare - TRAILER (ENG)

Lafora Disease: The Stories of Robin and Angelina

https://www.eurordis.org/robin-angelina-lafora/

Creating Awareness Connecting Families, Funding Research, Maintaining Hope.: Lafora disease: The stories of Robin & Angelina

The journeys of Robin and Angelina, two young individuals living with Lafora Disease, may be separated by thousands of miles, but they intertwine through shared experiences. Lafora disease, a terminal neurodegenerative condition affecting children, currently lacks a cure. EURORDIS sheds a light on Robin's and Angelina's stories and the brilliant work of the Chelsea’s Hope Lafora Children Research Fund. Would you like to share your story with us about life with a rare disease to support our Community article series? Contact Rhiannon Walls, our Communications Junior Manager, at rhiannon.walls@eurordis.org. https://chelseashope.org/

SATB2-Associated Syndrome Awareness Day

https://www.satb2europe.org/ Yesterday, on 22 August, our member organisation SATB2 Europe marked SATB2-Associated Syndrome Awareness Day. SATB2-Associated Syndrome (SAS), also known as Glass Syndrome or 2q33.1 Microdeletion Syndrome, is a rare genetic neurodevelopmental disorder caused by alterations of the SATB2 gene on the second chromosome. This syndrome significantly affects many organ systems and thus areas of development, primarily brain, palate, teeth and bones. To learn more about the experiences of those impacted by SAS, listen this discussion with Erika Stariha, the Founding President of SATB2 Europe and the mother of a boy with the condition. Is your organisation also aware of any upcoming awareness events that you would like to see promoted in the Community section of our monthly newsletter? If yes, contact our Communications Manager, Julien Poulain, at julien.poulain@eurordis.org.

How to START? Four pillars to optimally begin your orphan drug development

https://link.springer.com/article/10.1186/s13023-023-02845-9 Virginie Hivert, our Therapeutic Development Director, was a co-author in a position paper published this month by the Orphanet Journal of Rare Diseases. The position paper, 'How to START? Four pillars to optimally begin your orphan drug development' details best practices for initiating the process of developing medicines to treat rare conditions. The paper proposes a 'START' checklist relating to key considerations when starting an orphan drug development: STakeholder mapping, Available information on the disease, Resources, and Target patient value profile.

Living with Uncertainty & Impact of Trauma Mental Wellbeing Webinar August 2023 - 6 Sep 2023

https://www.eurordis.org/living-with-uncertainty-impact-of-trauma-mental-wellbeing-webinar/ People affected by a rare and undiagnosed condition live with an accumulative impact on their mental wellbeing. Specifically at an individual level, people living with a rare disease (PLWRD) can have an associated mental health co-morbidity, and at a population level, the community live with the increased psychological impact associated with the rare disease journey across all stages of life. Furthermore, the rare disease community has increased exposure to social inequality and discrimination, which are risk factors affecting poor mental wellbeing. The rare disease community has identified the need to look beyond the physiological symptoms of a rare condition, and recognise the importance of psychological support as a fully integrated part of the coordination of care. Without support, there will continue to be a detrimental impact on the mental health of those affected by rare conditions, hindering them from effective participation in society. This webinar will begin by breaking down the biopsychosocial continuum and addressing the intersectional needs of our community. It will then move on to a panel discussion on living with uncertainty and the impact of trauma, ending with a discussion on the impact of living with congential malformations. The outcome of the webinar will be the launch of a public call for expressions of interest to join the new EURORDIS Mental Wellbeing Partnership Network, where patient representatives will partner with experts to identify common mental health needs and inform EURORDIS’ strategic and policy action.

THE EUROPEAN PLATFORM FOR MEDICINES REPURPOSING

https://remedi4all.org/

Podcast: Rare on Air

https://www.eurordis.org/rare-on-air/ Finding new uses for existing medicines In our latest episode of Rare on Air, host Julien Poulain explores the potential of drug repurposing, which is the process by which new uses are discovered for already existing medicines. Julien is joined by Leonardo Panzeri, President of Italian Osteogenesis Imperfecta Association, and EURORDIS colleagues Claudia Fuchs and Judit Baijet, who all discuss the importance of patient advocates in drug repurposing efforts, as well as the EU-funded REMEDi4ALL project

CLINICAL TRIALS RESEARCH NEEDS RECOMMENDATIONS

https://www.rarediseasemoonshot.eu/wp-content/uploads/2023/07/Clinical-Trials-Research-Needs-Recommendations-1.pdf

BOOSTER TOWARD NEW SCIENTIFIC BREAKTROUGHS IN RARE AND PEDIATRIC DISEASES

https://www.rarediseasemoonshot.eu/ Rare Disease Moonshot, a coalition of seven organisations of which EURORDIS is a member, has issued recommendations to funders, researchers, patients, industry and other stakeholders on where public-private partnerships would bring most value in optimising clinical trials. The recommendations also include points to consider when setting up such collaborations that address the unmet needs of the rare disease community.

Welcome to the Best Practice Portal

https://webgate.ec.europa.eu/dyna/bp-portal/ Best practices in mental health Upon acknowledging the distinct mental wellbeing needs of those with chronic illnesses, the European Commission has launched a call for best practices on mental health. The Commission is seeking examples of best and promising practices on mental health from governmental and non-governmental entities, which can be submitted via the EU Best Practice Portal by Friday 29 September.

PDQ® Cancer Information Summaries for Health Professionals

https://www.cancer.gov/publications/pdq/information-summaries

Colorectal Cancer Prevention (PDQ®)–Health Professional Versionv

https://www.cancer.gov/types/colorectal/hp/colorectal-prevention-pdq?cid=eb_govdel#top

Cancer Screening Overview (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/screening/hp-screening-overview-pdq?cid=eb_govdel#top

Childhood Vascular Tumors Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/soft-tissue-sarcoma/hp/child-vascular-tumors-treatment-pdq?cid=eb_govdel#top

Childhood Soft Tissue Sarcoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/soft-tissue-sarcoma/hp/child-soft-tissue-treatment-pdq?cid=eb_govdel#top

Childhood Non-Hodgkin Lymphoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/lymphoma/hp/child-nhl-treatment-pdq?cid=eb_govdel#top

Childhood Hodgkin Lymphoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/lymphoma/hp/child-hodgkin-treatment-pdq?cid=eb_govdel#top

Parkinson’s disease gene variant found in study of some people of African ancestry

Parkinson’s disease gene variant found in study of some people of African ancestry NIH-supported, international study underscores importance of research of diverse populations. https://www.nih.gov/news-events/news-releases/parkinson-s-disease-gene-variant-found-study-some-people-african-ancestry

miércoles, 23 de agosto de 2023

First Complete Human Genome Poised to Strengthen Genetic Analysis, NIST Study Shows

https://www.nist.gov/news-events/news/2022/03/first-complete-human-genome-poised-strengthen-genetic-analysis-nist-study

Researchers Fully Sequence the Y Chromosome for the First Time August 23, 2023

https://www.nist.gov/news-events/news/2023/08/researchers-fully-sequence-y-chromosome-first-time

Including Spirituality Into a Fuller Picture of Research on Whole Person Health Director’s Page Helene M. Langevin, M.D.

https://www.nccih.nih.gov/about/offices/od/director/past-messages/including-spirituality-into-a-fuller-picture-of-research-on-whole-person-health?nav=govd

Researchers assemble the first complete sequence of a human Y chromosome

Researchers assemble the first complete sequence of a human Y chromosome New sequence reveals genomic factors in fertility, including sperm production. https://www.nih.gov/news-events/news-releases/researchers-assemble-first-complete-sequence-human-y-chromosome

The complete sequence of a human Y chromosome

https://www.nature.com/articles/s41586-023-06457-y

Researchers assemble the first complete sequence of a human Y chromosome

https://www.genome.gov/news/news-release/researchers-assemble-the-first-complete-sequence-of-a-human-y-chromosome

Researchers generate the first complete, gapless sequence of a human genome

https://www.genome.gov/news/news-release/researchers-generate-the-first-complete-gapless-sequence-of-a-human-genome

Y Chromosome Infographic: Researchers assemble the first complete sequence of a human Y chromosome

https://www.genome.gov/about-genomics/fact-sheets/Y-Chromosome-facts

MedWatch Online Voluntary Reporting Form: Correction: Hidden drug ingredients identified in products marketed for energy

https://www.accessdata.fda.gov/scripts/medwatch/index.cfm?utm_medium=email&utm_source=govdelivery Health Fraud Product Database https://www.fda.gov/consumers/health-fraud-scams/health-fraud-product-database?utm_medium=email&utm_source=govdelivery BIG GUYS Male Energy Supplement contains hidden drug ingredient https://www.fda.gov/drugs/medication-health-fraud/big-guys-male-energy-supplement-contains-hidden-drug-ingredient?utm_medium=email&utm_source=govdelivery Mens Maximum Energy Supplement contains hidden drug ingredient https://www.fda.gov/drugs/medication-health-fraud/mens-maximum-energy-supplement-contains-hidden-drug-ingredient?utm_medium=email&utm_source=govdelivery Round 2 contains hidden drug ingredient https://www.fda.gov/drugs/medication-health-fraud/round-2-contains-hidden-drug-ingredient?utm_medium=email&utm_source=govdelivery Genergy contains hidden drug ingredient https://www.fda.gov/drugs/medication-health-fraud/genergy-contains-hidden-drug-ingredient?utm_medium=email&utm_source=govdelivery WeFun contains hidden drug ingredient https://www.fda.gov/drugs/medication-health-fraud/wefun-contains-hidden-drug-ingredient?utm_medium=email&utm_source=govdelivery X MAX Triple Shot Energy Honey contains hidden drug ingredient https://www.fda.gov/drugs/medication-health-fraud/x-max-triple-shot-energy-honey-contains-hidden-drug-ingredient?utm_medium=email&utm_source=govdelivery

Only 1 in 5 U.S. adults with opioid use disorder received medications to treat it in 2021

https://www.nih.gov/news-events/news-releases/only-1-5-us-adults-opioid-use-disorder-received-medications-treat-it-2021

Aspirin for Secondary CVD Prevention Underused Worldwide Megan Brooks

https://www.medscape.com/viewarticle/995728?src=

COVID Cases Continue to Rise as Nation Awaits Updated Vaccine Lisa O'Mary

https://www.medscape.com/s/viewarticle/995727

We Hope to See You at the World Congress of Pediatric Cardiology and Cardiac Surgery

https://www.wcpccs2023.org/event/1da8563e-0f65-486c-88df-70c3db431af5/summary

STARTUP AIMING TO KEEP KIDNEY PATIENTS OFF DIALYSIS

STARTUP AIMING TO KEEP KIDNEY PATIENTS OFF DIALYSIS Electro-hydraulic acoustic therapy could treat late-stage chronic kidney disease and delay its progression by up to a year. https://www.israel21c.org/startup-aiming-to-keep-kidney-patients-off-dialysis/

AI cancer startup collaborates with top Israeli hospital

AI cancer startup collaborates with top Israeli hospital Cloud platform enables whole genome sequencing from data derived from blood tests that can detect recurring cancer early on. https://www.israel21c.org/ai-cancer-startup-collaborates-with-top-israeli-hospital/

Debulking Primary Disease: Does It Spur Micro-Metastases? David J. Kerr, CBE, MD, DSc

https://www.medscape.com/viewarticle/989984?ecd=mkm_ret_230823_mscpmrk_onc_crc_etid5777226&uac=148436CN&impID=5777226

Early-Life Antibiotic Use Raises Risk of Early-Onset CRC Megan Brooks

https://www.medscape.com/viewarticle/995173?ecd=mkm_ret_230823_mscpmrk_onc_crc_etid5777226&uac=148436CN&impID=5777226

Diabetes Discoveries & Practice Blog How Does Stigma Affect Patients with Overweight, Obesity, or Diabetes?

https://www.niddk.nih.gov/health-information/professionals/diabetes-discoveries-practice/how-stigma-affects-patients-with-overweight-obesity-or-diabetes?utm_medium=e-mail&utm_source=diabetes+discoveries+and+practice+blog

Qigong: What You Need To Know

https://www.nccih.nih.gov/health/qigong-what-you-need-to-know?nav=govd

An mRNA vaccine to treat pancreatic cancer

https://www.nih.gov/news-events/nih-research-matters/mrna-vaccine-treat-pancreatic-cancer

Genetic variant associated with absence of COVID-19 symptoms

https://www.nih.gov/news-events/nih-research-matters/genetic-variant-associated-absence-covid-19-symptoms

Lizard tails give clues to cartilage formation

https://www.nih.gov/news-events/nih-research-matters/lizard-tails-give-clues-cartilage-formation

SARS-CoV-2 can cause lasting damage to cells’ energy production

https://www.nih.gov/news-events/nih-research-matters/sars-cov-2-can-cause-lasting-damage-cells-energy-production

Ancestry and descendants of African Americans buried at Catoctin Furnace

https://www.nih.gov/news-events/nih-research-matters/ancestry-descendants-african-americans-buried-catoctin-furnace

4 Tips: Start Talking With Your Health Care Providers About Complementary Health Approaches

https://www.nccih.nih.gov/health/tips/tips-start-talking-with-your-health-care-providers-about-complementary-health-approaches?nav=govd

Implementing sustainable global mental health in a fragmenting world

https://www.thelancet.com/lancet-200/mental-health?dgcid=hubspot_update_feature_lancet200_mh_ebiom&utm_campaign=update-ebiom&utm_medium=email&_hsmi=271299200&_hsenc=p2ANqtz--oW0D22w7xiKHgsyvWepjLWn4NGJDUp7TiPfDiy7xByrrRi4BNKJj6gKC3hrPfAE3NQa7aEtoyZb_szfB41JS4dMHifw&utm_content=271252544&utm_source=hs_email

eBioMedicine in conversation with John Cryan on the microbiome-gut-brain axis and binge drinking

https://ebiomedicine.buzzsprout.com/1809873/13284571-john-cryan-on-the-microbiome-gut-brain-axis-and-binge-drinking?utm_campaign=update-ebiom&utm_medium=email&_hsmi=271299200&_hsenc=p2ANqtz-_TS3eoyFOvS6rZSrBvbM812y9xc7yp9qgYE8uZ48qssHGrhmSclxJp9S7xqSxVkgW_lEhdFvBOWKv5Mi90O4muG1gUfQ&utm_content=271252544&utm_source=hs_email

Plasma lipids are dysregulated preceding diagnosis of preeclampsia or delivery of a growth restricted infant

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00269-4/fulltext?dgcid=hubspot_update_feature_updatealerts_ebiom&utm_campaign=update-ebiom&utm_medium=email&_hsmi=271299200&_hsenc=p2ANqtz-90HSWHz78i37g_4LmXt3OY4cJRTcJxZvdh--T45ACQdyXCtyDgtPnORUf6IwxFVM1x6_BA5BAwa2ZjQP-IdGL2hfMFww&utm_content=271252544&utm_source=hs_email

About the Global Burden of Disease

https://www.thelancet.com/gbd?dgcid=hubspot_update_feature_updatealerts_ebiom&utm_campaign=update-ebiom&utm_medium=email&_hsmi=271299200&_hsenc=p2ANqtz-_jc5cy07p3P0cP7B2czW9PkPfl24oODq5fd3kfwDZ0aa_goEzpF0yfS5x48-wawxky-1N9EYumhfVsHHRX6tU1_EWoqw&utm_content=271252544&utm_source=hs_email

Sources of gut microbiota variation in a large longitudinal Finnish infant cohort

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00260-8/fulltext?dgcid=hubspot_update_feature_updatealerts_ebiom&utm_campaign=update-ebiom&utm_medium=email&_hsmi=271299200&_hsenc=p2ANqtz-_MJ15ZrIk1YO6Rw_omaTm99Kyji_XW-yamugkq3siZbIpXEg1IncTzQsd6h6nx5H3MxcoaKTe5zSXC4HRuqfs9EllNrA&utm_content=271252544&utm_source=hs_email

Hippocampal subfield abnormalities and biomarkers of pathologic brain changes: from SARS-CoV-2 acute infection to post-COVID syndrome

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00276-1/fulltext?dgcid=hubspot_update_feature_updatealerts_ebiom&utm_campaign=update-ebiom&utm_medium=email&_hsmi=271299200&_hsenc=p2ANqtz-9oaMUdHTQn-8k0kAQTcOEKzzlSccM3xE4X9XcMzKLpsAep7iX3r_2xKDIBDsxrjD5ebvNwBwltxsDdGFwMlel16OblaQ&utm_content=271252544&utm_source=hs_email

Drug Trials Snapshot: LUMAKRAS (SOTORASIB)

LUMAKRAS is a drug used to treat adult patients with non-small cell lung cancer (NSCLC) that is locally advanced or has spread to other parts of the body (metastatic). It should be used in patients who have been treated with at least one prior type of therapy and whose cancer has a certain type of genetic mutation (KRAS G12C). https://www.fda.gov/drugs/drug-approvals-and-databases/drug-trials-snapshot-lumakras

Tainted Sexual Enhancement Products: Hidden drug ingredients identified in products promoted for sexual enhancement

https://www.fda.gov/drugs/medication-health-fraud/tainted-sexual-enhancement-products?utm_medium=email&utm_source=govdelivery

martes, 22 de agosto de 2023

Bridget Williams-Simmons, Ph.D. Associate Director for Basic Research and Director of the Office of Science Policy and Communications, National Institute on Alcohol Abuse and Alcoholism

Bridget Williams-Simmons, Ph.D. Associate Director for Basic Research and Director of the Office of Science Policy and Communications, National Institute on Alcohol Abuse and Alcoholism https://www.spectrum.niaaa.nih.gov/spring2023fivequestions

Including Spirituality Into a Fuller Picture of Research on Whole Person Health

https://www.nccih.nih.gov/about/offices/od/director/past-messages/including-spirituality-into-a-fuller-picture-of-research-on-whole-person-health?nav=govd

Safety and efficacy of mirikizumab versus secukinumab and placebo in the treatment of moderate-to-severe plaque psoriasis (OASIS-2): a phase 3, multicentre, randomised, double-blind study

https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(23)00120-0/fulltext

Evaluating the safety and short-term equivalence of colchicine versus prednisone in older patients with acute calcium pyrophosphate crystal arthritis (COLCHICORT): an open-label, multicentre, randomised trial

https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(23)00165-0/fulltext

Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021 Steinmetz et al.

Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021 https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(23)00163-7/fulltext Steinmetz et al. https://www.thelancet.com/journals/lanrhe/home

Multiple switching between the biosimilar adalimumab PF-06410293 and reference adalimumab in patients with active rheumatoid arthritis: a phase 3, open-label, randomised, parallel-group study Fleischmann et al.

Multiple switching between the biosimilar adalimumab PF-06410293 and reference adalimumab in patients with active rheumatoid arthritis: a phase 3, open-label, randomised, parallel-group study https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(23)00161-3/fulltext Fleischmann et al. https://www.thelancet.com/journals/lanrhe/home

How to Feed a Macrophage Posted on August 22nd, 2023 by Lawrence Tabak, D.D.S., Ph.D.

https://directorsblog.nih.gov/2023/08/22/how-to-feed-a-macrophage/

Healthy brain in a healthy body Rui Araújo

https://www.thelancet.com/journals/laneur/issue/current

Preparing for disease-modifying therapies in Alzheimer's disease Christopher R S Belder,Jonathan M Schott,Nick C Fox

https://www.thelancet.com/journals/laneur/issue/current

Brain health, disability, and the need for broader thinking The Lancet Neurology

https://www.thelancet.com/journals/laneur/issue/current

Bivalent COVID-19 mRNA vaccine against omicron subvariants in immunocompromised patients

https://www.thelancet.com/journals/laninf/issue/current

Public policy and health in the USA miniseries: should investors own healthcare?

Public policy and health in the USA miniseries: should investors own healthcare? We are pleased to invite you to the latest event in our webinar miniseries public policy and health in the USA: should investors own healthcare?, Sept 26, 2023, at 14:00 EDT / 19:00 BST. Attendance is free and you can register for the webinar here. Tues, Sept 26, 2023 13:00 EDT / 19:00 BST https://event.on24.com/wcc/r/4261292/F83D33EB8BF67FD27D747E69F489D5E3?partnerref=hubspot_email_usinvestorshealthcare23_registration1&utm_campaign=usinvestorshealthcare23&utm_medium=email&_hsenc=p2ANqtz-9ocO9UuCNqvKDrzEYJ4NqsucxlkH4si8Pvdc_LiQ_tZ1BnsGCRL_Mk8lY_hDR8rnMhMhyPnzZl69BlgfJvEwRxLwXlYA&_hsmi=271132250&utm_content=270638876&utm_source=hs_email&hsCtaTracking=cf00ab02-c5b8-41eb-bf53-576b7acd0223%7Ce1788eb8-7603-46d7-8148-fb0020a6a949

Food & You: the utility of a digital cohort for personalized nutrition studies

https://www.news-medical.net/news/20230822/Food-You-the-utility-of-a-digital-cohort-for-personalized-nutrition-studies.aspx

Are irregular sleep patterns associated with increased mortality risk?

https://www.news-medical.net/news/20230822/Are-irregular-sleep-patterns-associated-with-increased-mortality-risk.aspx

Study explores mechanism behind liraglutide-associated weight loss in obese individuals

https://www.news-medical.net/news/20230822/Study-explores-mechanism-behind-liraglutide-associated-weight-loss-in-obese-individuals.aspx

Could plant-based diets help treat cardiovascular diseases?

https://www.news-medical.net/news/20230822/Could-plant-based-diets-help-treat-cardiovascular-diseases.aspx

Less is more: Radiotherapy omission deemed safe for certain breast cancer patients

https://www.news-medical.net/news/20230822/Less-is-more-Radiotherapy-omission-deemed-safe-for-certain-breast-cancer-patients.aspx

What is the effect of a workplace-based nutritional and behavioral intervention on adherence to Mediterranean diet principles at 12 months?

https://www.news-medical.net/news/20230822/What-is-the-effect-of-a-workplace-based-nutritional-and-behavioral-intervention-on-adherence-to-Mediterranean-diet-principles-at-12-months.aspx

Climate Change and Health Equity

https://www.hhs.gov/climate-change-health-equity-environmental-justice/climate-change-health-equity/index.html?utm_source=news-releases-email&utm_medium=email&utm_campaign=august-21-2023

Climate Change and Your Health

Why Blood Type Seems to Be Linked With COVID-19 Risk

https://pubmed.ncbi.nlm.nih.gov/37585180/

Your cells don’t have the genome you were born with. Project aims to chart impact of new mutations

https://www.science.org/content/article/your-cells-don-t-have-genome-you-were-born-project-aims-chart-impact-new-mutations

Headway against Brain Tumors with Molecular Targeting of IDH-Mutant Gliomas

https://pubmed.ncbi.nlm.nih.gov/37585632/

Gene Therapy in Patients with the Crigler-Najjar Syndrome

https://pubmed.ncbi.nlm.nih.gov/37585628/

What Is Huntington Disease?

https://jamanetwork.com/journals/jama/fullarticle/2808794

FDA Approves First Vaccine for Pregnant Individuals to Prevent RSV in Infants

FDA Approves First Vaccine for Pregnant Individuals to Prevent RSV in Infants https://www.fda.gov/news-events/press-announcements/fda-approves-first-vaccine-pregnant-individuals-prevent-rsv-infants?utm_medium=email&utm_source=govdelivery

lunes, 21 de agosto de 2023

ZOOMED OUT: REBOOTING YOUR VIRTUAL ENGAGEMENT

Zoomed Out: Rebooting Your Virtual Communication By Ivanhoe Broadcast News on August 27, 2023 https://www.ivanhoe.com/?p=31074&preview=1&_ppp=75cd9ee51b

OUTGROWING PENICILLIN ALLERGY?

Outgrowing Penicillin Allergy? By Ivanhoe Broadcast News on August 25, 2023 https://www.ivanhoe.com/?p=31089&preview=1&_ppp=d1ee3adef4

TOO MUCH EXERCISE: CAN IT HURT YOUR HEART?

Too Much Exercise: Can it Hurt Your Heart? By Ivanhoe Broadcast News on August 24, 2023 https://www.ivanhoe.com/?p=31092&preview=1&_ppp=c9d2407318

BORN WITH AVM: A SILENT KILLER OF YOUNG PEOPLE

Born with AVM: A Silent Killer of Young People By Ivanhoe Broadcast News on August 23, 2023 https://www.ivanhoe.com/?p=31086&preview=1&_ppp=ff996ecdea

BATTLING OBESITY IN TEENS: GROUNDBREAKING GUIDELINES FOR CHILDREN

Battling Obesity in Teens: Groundbreaking Guidelines for Children By Ivanhoe Broadcast News on August 22, 2023 https://www.ivanhoe.com/?p=31083&preview=1&_ppp=045cc5f9d2

CANCER & ORGAN TRANSPLANT CLINIC

Cancer & Organ Transplant Clinic By Ivanhoe Broadcast News on August 21, 2023 https://www.ivanhoe.com/?p=31080&preview=1&_ppp=ee39ee1a79

Associations between alcohol intake, cancer risk, and modifying factors in women: smoking, BMI, and MHT interactions

https://www.news-medical.net/news/20230821/Associations-between-alcohol-intake-cancer-risk-and-modifying-factors-in-women-smoking-BMI-and-MHT-interactions.aspx

How effective is the keto diet for managing PCOS?

https://www.news-medical.net/news/20230821/How-effective-is-the-keto-diet-for-managing-PCOS.aspx

How did exposure to health information and media health literacy affect fruit and vegetable consumption among Thai youth?

https://www.news-medical.net/news/20230821/How-did-exposure-to-health-information-and-media-health-literacy-affect-fruit-and-vegetable-consumption-among-Thai-youth.aspx

The interplay between the microbiota, the epigenome, and nutrition among obese adults during behavioral weight reduction

https://www.news-medical.net/news/20230821/The-interplay-between-the-microbiota-the-epigenome-and-nutrition-among-obese-adults-during-behavioral-weight-reduction.aspx

Is there an association between cannabis usage motives and problematic cannabis usage in young adults?

https://www.news-medical.net/news/20230821/Is-there-an-association-between-cannabis-usage-motives-and-problematic-cannabis-usage-in-young-adults.aspx

Vegetarianism: what are the health benefits?

https://www.news-medical.net/news/20230821/Vegetarianism-what-are-the-health-benefits.aspx

The standard of care and recent advancements in the control of skin inflammation

https://www.news-medical.net/news/20230821/The-standard-of-care-and-recent-advancements-in-the-control-of-skin-inflammation.aspx

Evaluation of a smartphone app's impact on reducing unhealthy alcohol consumption in university students: A randomized controlled study

https://www.news-medical.net/news/20230821/Evaluation-of-a-smartphone-apps-impact-on-reducing-unhealthy-alcohol-consumption-in-university-students-A-randomized-controlled-study.aspx

Associations between cardiorespiratory fitness in young men and the incidence of site-specific cancer

https://www.news-medical.net/news/20230821/Associations-between-cardiorespiratory-fitness-in-young-men-and-the-incidence-of-site-specific-cancer.aspx

Abdominal obesity and hydration status as protective factors against mortality in older adults: A prospective study Jarson Pedro da Costa Pereira, ... Poliana Coelho Cabral December 2023

Abdominal obesity and hydration status as protective factors against mortality in older adults: A prospective study Jarson Pedro da Costa Pereira, ... Poliana Coelho Cabral December 2023 https://www.sciencedirect.com/journal/nutrition

Effect of timing of enteral nutrition initiation on poor prognosis in patients after cardiopulmonary bypass: a prospective observational study

https://www.sciencedirect.com/science/article/pii/S0899900723002253

Cardiorenal interactions in heart failure – insights from recent therapeutic advances

https://academic.oup.com/cardiovascres/advance-article/doi/10.1093/cvr/cvad096/7207893?login=false

domingo, 20 de agosto de 2023

More than Meets the Eye: New Research Shows How the Visual System Contributes to Memory

https://www.nyu.edu/about/news-publications/news/2023/august/more-than-meets-the-eye--new-research-shows-how-the-visual-syste.html

Metaplastic breast cancer and BRCA1: first strong evidence of a link

https://www.nature.com/articles/s41431-023-01441-6

Pan American League of Associations for Rheumatology Guidelines for the treatment of ANCA-associated vasculitis

https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(23)00128-5/fulltext "Gender bias is as entrenched as ever…with a shocking 9 out of 10 people globally reporting biases against women. It is imperative that we regain—and maintain—momentum in the drive to improve global gender equity." https://www.thelancet.com/journals/lanrhe/home

Prediabetes: never too early to intervene

https://www.thelancet.com/journals/landia/article/PIIS2213-8587(23)00152-3/fulltext Aug 2023 Volume 11Number 8p525-624, e10 https://www.thelancet.com/journals/landia/issue/current

Illness severity assessment of older adults in critical illness using machine learning (ELDER-ICU): an international multicentre study with subgroup bias evaluation

https://www.thelancet.com/journals/landig/article/PIIS2589-7500(23)00128-0/fulltext

Time to rethink behaviours that challenge in people with intellectual disabilities Angela Hassiotis

https://www.thelancet.com/journals/lanpsy/issue/current

Spotlight on Universal Health Coverage: assessing expectations ahead of the UN High-Level Meeting on UHC

https://event.on24.com/wcc/r/4275494/4063DA1B3D4FDA6B111A5BA1A546D6AD?partnerref=hubspot_email_lancet200_uhc_webinar1_registration1&utm_campaign=lancet200&utm_medium=email&_hsenc=p2ANqtz-_MWN8pVeYtJi9nflxnIRvyAee8aFeYVcFXrF_RWLfx3qokcmQIVOvnfhUNQ-e-iAbCpKSwNsmI4vxrITyeMJOmYyGYAQ&_hsmi=270222924&utm_content=269894305&utm_source=hs_email&hsCtaTracking=675e25e7-b9d1-422f-9882-6755409dad34%7Cd00abdcb-653f-42a1-a276-aaa456044146

Severe COVID-19 may lead to long-term innate immune system changes

https://www.nih.gov/news-events/news-releases/severe-covid-19-may-lead-long-term-innate-immune-system-changes

sábado, 19 de agosto de 2023

Curious about your cancer risk, or if your child might develop learning disabilities? There’s a genetic test for that—but it may not be accurate E Prater, Fortune Well, July 2023

Curious about your cancer risk, or if your child might develop learning disabilities? There’s a genetic test for that—but it may not be accurate E Prater, Fortune Well, July 2023 https://phgkb.cdc.gov/PHGKB/specificPHGKB.action?topic=cancer&query=home

Cluster of carbapenemase-producing carbapenem-resistant Pseudomonas aeruginosa among patients in an adult intensive care unit - Idaho, 2021-2022 Cahill ME , Jaworski M , Harcy V , Young E , Ham DC , Gable P , Carter KK .

Cluster of carbapenemase-producing carbapenem-resistant Pseudomonas aeruginosa among patients in an adult intensive care unit - Idaho, 2021-2022 Cahill ME , Jaworski M , Harcy V , Young E , Ham DC , Gable P , Carter KK . https://phgkb.cdc.gov/PHGKB/cdcPubFinder.action?Mysubmit=update

The effect of personalized intelligent digital systems for self-care training on type II diabetes: a systematic review and meta-analysis of clinical trials. Mozhgan Tanhapour et al. Acta Diabetol 2023

The effect of personalized intelligent digital systems for self-care training on type II diabetes: a systematic review and meta-analysis of clinical trials. Mozhgan Tanhapour et al. Acta Diabetol 2023 https://phgkb.cdc.gov/PHGKB/translationClip.action?action=nonGhome

Key alert system for disease outbreaks is in crisis — can it be saved? Kozlov M. Nature, Aug 10, 2023.

https://phgkb.cdc.gov/PHGKB/amdClip.action?action=home

Molecular testing for indeterminate thyroid nodules: past, present, and future. Rajam Raghunathan et al. Curr Opin Endocrinol Diabetes Obes 2023

https://phgkb.cdc.gov/PHGKB/translationClip.action?action=home

Empowering women's health: BGI Genomics Global 2023 state of cervical cancer awareness report

https://www.news-medical.net/whitepaper/20230815/Empowering-Womens-Health-BGI-Genomics-Global-2023-State-of-Cervical-Cancer-Awareness-Report.aspx

What is Ocular Albinism?

Ocular albinism (OA) is an inherited genetic condition that primarily affects the pigments in the eyes. https://www.news-medical.net/health/What-is-Ocular-Albinism.aspx

What is Akathisia?

Akathisia is a common movement disorder associated with the use of antipsychotic medications. https://www.news-medical.net/health/What-is-Akathisia.aspx

What is Crimean-Congo Hemorrhagic Fever?

https://www.news-medical.net/health/What-is-Crimean-Congo-Hemorrhagic-Fever.aspx

Study finds inverse correlation between dietary magnesium intake and peripheral arterial disease

https://www.news-medical.net/news/20230816/Study-finds-inverse-correlation-between-dietary-magnesium-intake-and-peripheral-arterial-disease.aspx

Severe COVID-19 may cause long-term changes to innate immune system

https://www.news-medical.net/news/20230818/Severe-COVID-19-may-cause-long-term-changes-to-innate-immune-system.aspx

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults - Non-alcoholic fatty liver disease (NAFLD)

https://www.news-medical.net/news/20230818/Meta-analysis-reports-global-prevalence-of-MAFLD-of-38825-in-adults.aspx

New genes linked to breast cancer risk identified

https://www.news-medical.net/news/20230818/New-genes-linked-to-breast-cancer-risk-identified.aspx

The association between diet pattern and depressive and anxiety symptoms

https://www.news-medical.net/news/20230818/The-association-between-diet-pattern-and-depressive-and-anxiety-symptoms.aspx

FDA approves first treatment for CD55-deficient protein-losing enteropathy (CHAPLE disease) Veopoz (pozelimab-bbfg)

https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-first-treatment-cd55-deficient-protein-losing-enteropathy-chaple-disease?utm_medium=email&utm_source=govdelivery