CIENCIASMEDICASNEWS: febrero 2022

lunes, 28 de febrero de 2022

CROI 2022 — COVID-19 pneumonia: methylprednisolone pulse therapy added to dexamethasone shows no benefit

ASH 2021 Highlights & Complete Coverage | Univadis

domingo, 27 de febrero de 2022

COVID-19 GPH|Home|PHGKB

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Using Pharmacogenetics to Enhance Tuberculosis (TB) Treatment | Blogs | CDC

CDC-Authored Publications Update|PHGKB

Precision Health Database| Non-Genomics Precision Health Weekly Scan|PHGKB

Advanced Molecular Detection Clips Database|AMD Clips|PHGKB

Precision Health Database| Genomics Precision Health Weekly Scan|PHGKB

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More Detailed Information on Key Tier 1 Applications - Lynch Syndrome | CDC

The Current Landscape of CDC Publications in Human Genomics and Public Health | Blogs | CDC

Precision Public Health in Action: New CDC Pilot Projects Integrate Human Genomics into Public Health Surveillance and Applied Research | Blogs | CDC

ISC 2022 — Large infarction stroke: thrombectomy improves functional outcomes but at the cost of increased bleeding

ISC 2022 — Hypotension after intracerebral hemorrhage tied to higher mortality risk

ISC 2022 — Cerebral venous thrombosis: DOACs on par with warfarin in a real-world setting

ISC 2022 — Children with LVO stroke have worse outcomes without mechanical thrombectomy

ISC 2022 — New AHA scientific statement outlines best practices for in-hospital stroke care

ASH 2021 Highlights & Complete Coverage | Univadis

A new study says the constant pressure to be happy leads to a sense of gloom and misery | Lifestyle News,The Indian Express

sábado, 26 de febrero de 2022

First report from the German COVID-19 autopsy registry - The Lancet Regional Health – Europe

Social vulnerability indices: A pragmatic tool for COVID-19 policy and beyond - The Lancet Regional Health – Europe

Which children and young people are at higher risk of severe disease and death after hospitalisation with SARS-CoV-2 infection in children and young people: A systematic review and individual patient meta-analysis - eClinicalMedicine

Which children and young people are at higher risk of severe disease and death after hospitalisation with SARS-CoV-2 infection in children and young people: A systematic review and individual patient meta-analysis - eClinicalMedicine

A systematic review of de-escalation strategies for redeployed staff and repurposed facilities in COVID-19 intensive care units (ICUs) during the pandemic - eClinicalMedicine

Wolfgang Preiser—co-discoverer of SARS-CoV-2 variants - The Lancet Infectious Diseases

Real-world serological responses to extended-interval and heterologous COVID-19 mRNA vaccination in frail, older people (UNCoVER): an interim report from a prospective observational cohort study - The Lancet Healthy Longevity

Real-world serological responses to extended-interval and heterologous COVID-19 mRNA vaccination in frail, older people (UNCoVER): an interim report from a prospective observational cohort study - The Lancet Healthy Longevity

COVID-19 immunisation in older people - The Lancet Healthy Longevity

Integrative approaches required to support children affected by COVID-19 - The Lancet Child & Adolescent Health

Global, regional, and national minimum estimates of children affected by COVID-19-associated orphanhood and caregiver death, by age and family circumstance up to Oct 31, 2021: an updated modelling study - The Lancet Child & Adolescent Health

Global, regional, and national minimum estimates of children affected by COVID-19-associated orphanhood and caregiver death, by age and family circumstance up to Oct 31, 2021: an updated modelling study - The Lancet Child & Adolescent Health

When vaccine adverse event reporting generates hope, not fear - The Lancet Child & Adolescent Health

Reported cases of multisystem inflammatory syndrome in children aged 12–20 years in the USA who received a COVID-19 vaccine, December, 2020, through August, 2021: a surveillance investigation - The Lancet Child & Adolescent Health

Reported cases of multisystem inflammatory syndrome in children aged 12–20 years in the USA who received a COVID-19 vaccine, December, 2020, through August, 2021: a surveillance investigation - The Lancet Child & Adolescent Health

SARS-CoV-2 spread and hospitalisations in paediatric patients during the omicron surge - The Lancet Child & Adolescent Health

Paediatric hospitalisations due to COVID-19 during the first SARS-CoV-2 omicron (B.1.1.529) variant wave in South Africa: a multicentre observational study - The Lancet Child & Adolescent Health

Vaccine apartheid: global cooperation and equity - The Lancet

Understanding of COVID-19 from infection–fatality ratio - The Lancet

Variation in the COVID-19 infection–fatality ratio by age, time, and geography during the pre-vaccine era: a systematic analysis - The Lancet

Waning of COVID-19 vaccine effectiveness: individual and public health risk - The Lancet

Duration of effectiveness of vaccines against SARS-CoV-2 infection and COVID-19 disease: results of a systematic review and meta-regression - The Lancet

FDA updates Sotrovimab emergency use authorization | FDA

viernes, 25 de febrero de 2022

BMC Cancer | Home page

BMC Pharmacology and Toxicology | Home page

Orphanet Journal of Rare Diseases | Home page

First Recording of Dying Brain Shows Memory Patterns

Some People Can Wait 8 Weeks Between First 2 Vaccine Doses: CDC

FDA authorizes revisions to Evusheld dosing | FDA

Seeking Consensus on the Use of Population Descriptors in Genomics – NIH Director's Blog

Opportunity for Public Comment | United States Preventive Services Taskforce - Public Comment on Draft Recommendation Statement and Draft Evidence Review: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults

Opportunity for Public Comment | United States Preventive Services Taskforce

Fact Sheet for Patients, Parents and Caregivers Emergency Use Authorization (EUA) of Bebtelovimab for Coronavirus Disease 2019 (COVID-19)

Fact Sheet for Healthcare Providers: Emergency Use Authorization for Bebtelovimab

FDA Approves Treatment for Wider Range of Patients with Heart Failure | FDA

PMA-based PCR amplifies DNA from only live bacteria in urine - Children's National

Approved first generic for Apokyn injection cartridges requires separately packaged pen | FDA

TNBC: atezolizumab fails to improve pCR in NeoTRIP trial

Breakthrough COVID-19 in patients with rheumatic diseases

COVID-19 vaccine effectiveness beyond nine months

COVID-19 mRNA vaccination during pregnancy

COVID-19: next-generation inhaled trivalent vaccine

COVID-19: maternal vaccination (vs natural infection) tied to more durable anti-spike IgG titers in infants

Children & Screen Time | Heart Health | COVID-19 Vaccines & Fertility | Cannabis & Cancer | Infant Hearing Screening

Antibody (Serology) Testing for COVID-19: Information for Patients and Consumers | FDA

jueves, 24 de febrero de 2022

Rate of Overdue Cervical Cancer Screening Is Increasing - National Cancer Institute

Commit to transparent COVID data until the WHO declares the pandemic is over

Will a rising Omicron variant scramble antibody treatments?

Why does the Omicron sub-variant spread faster than the original?

Patterns of Cannabis and Alcohol Co-Use: Substitution Versus Complementary Effects | Alcohol Research: Current Reviews

Yohimbe | NCCIH

Women’s experiences of sexual assault and harassment linked with high blood pressure | National Institutes of Health (NIH)

At-Home OTC COVID-19 Diagnostic Tests | FDA

How Consumers Can Report an Adverse Event or Serious Problem to FDA | FDA

Pregnant? Breastfeeding? FDA Aims to Improve Drug Information | FDA

Tips for Women to Prevent Heart Disease | FDA

Medical Device Cybersecurity: What You Need to Know | FDA

FDA Alerts the Public to Potentially Contaminated Products from Family Dollar Stores in Six States | FDA

Tianeptine Products Linked to Serious Harm, Overdoses, Death | FDA

FDA investigating possible increased risk of death with lymphoma medicine Ukoniq (umbralisib) | FDA

FDA Warns Consumers Not to Use Certain Powdered Infant Formula Produced in Abbott Nutrition’s Facility in Sturgis, Michigan | FDA

Are You Considering a Complementary Health Approach? | NCCIH

Guidance for COVID-19 and People with HIV | NIH

Beijing 2022: why some athletes struggle with their mental health after the Olympics | Lifestyle News,The Indian Express

Explained: How umbilical cord blood was used to cure an HIV patient | Explained News,The Indian Express

martes, 22 de febrero de 2022

NIH’s Dr. Carl Dieffenbach Discusses Highlights of HIV Cure, Treatment and Prevention Research from CROI 2022 | NIH: National Institute of Allergy and Infectious Diseases

Covid-19: Fourth vaccine doses—who needs them and why? | The BMJ

Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year | Nature Medicine

Effectiveness of the BNT162b2 Vaccine after Recovery from Covid-19 | NEJM

Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection | NEJM

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 | NEJM

Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities: The I-TECH Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA Internal Medicine | JAMA Network

Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities: The I-TECH Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA Internal Medicine | JAMA Network

Is it time to live with COVID-19? Some scientists warn of ‘endemic delusion’ | Science | AAAS

Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus | European Heart Journal | Oxford Academic

ESCMID rapid guidelines for assessment and management of long COVID - Clinical Microbiology and Infection

Risks of mental health outcomes in people with covid-19: cohort study | The BMJ

Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year | Nature Medicine

Vaccines to prevent COVID-19: A living systematic review with Trial Sequential Analysis and network meta-analysis of randomized clinical trials

Risk Factors for Severe COVID-19 in Children | Pediatrics | American Academy of Pediatrics

Efficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials | BMC Infectious Diseases | Full Text

Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review - The Lancet Global Health

Temperature control after cardiac arrest: European experts release new guideline

Tirzepatide added to glargine reduces HbA1c in patients with type 2 diabetes

Researchers detect microRNA biomarkers for HCC in saliva

COVID-19 Around the world weekly highlights: lifting protection measures, cyberattacks, and the first case in the Cook Islands…

COVID-19: maternal vaccination (vs natural infection) tied to more durable anti-spike IgG titers in infants

lunes, 21 de febrero de 2022

Treatment with direct-acting antivirals reduces emergency visits, hospitalizations among hepatitis C patients

Behavioral scientist to present findings from the Northwestern Juvenile Project at AAAS meeting

Impact of COVID-19 lockdown on BMI of obese and normal-weight children in Switzerland

Study suggests non-classical inhibition of TBK1/IKKε is protective against severe COVID-19 immunopathology in vivo

Poll: Most parents have limited knowledge about CBD products for children

The Clinical Importance of Immunogenetics

What is Mucosal Immunity?

The Immune System and the Microbiome in Health and Disease

Study measures recovery rate of SARS-CoV-2-induced olfactory loss

The effect of COVID-19 vaccination on long COVID symptoms

Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Orphanet Journal of Rare Diseases | Home page

Flurona: How likely are you to get both COVID and the flu simultaneously? - Genetic Literacy Project

Explained: What’s going on with Covid-19 vaccines for children under 5? | Explained News,The Indian Express

Guide to eat right: Explore the connection between gut health, vitamin D and immunity | Lifestyle News,The Indian Express

More teenage girls with eating disorders wound up in the ER during the pandemic | Lifestyle News,The Indian Express

Post Covid-19 complications: Skin issues, joint pain becoming increasingly common, say experts | Lifestyle News,The Indian Express

domingo, 20 de febrero de 2022

Specific PHGKB|Reproductive and Child Health PHGKB|PHGKB

Time to make rare disease diagnosis accessible to all HL Rehm, Nature Medicine, February 7, 2022

Specific PHGKB|Rare Diseases PHGKB|PHGKB

Characterizing SARS-CoV-2 transcription of subgenomic and genomic RNAs during early human infection using multiplexed ddPCR External Web Site Icon HS Hwang et al, MEDRXIV, February 19,2022

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Characterizing SARS-CoV-2 transcription of subgenomic and genomic RNAs during early human infection using multiplexed ddPCR HS Hwang et al, MEDRXIV, February 19,2022

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Newly Diagnosed: What to do when you’re newly diagnosed with Familial Hypercholesterolemia or High Lipoprotein(a) Family Heart Foundation February, 2022

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Lynch Syndrome FORCE, February 2022

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CDC-Authored Publications Update|PHGKB

Precision Health Database| Non-Genomics Precision Health Weekly Scan|PHGKB

Advanced Molecular Detection Clips Database|AMD Clips|PHGKB

Precision Health Database| Genomics Precision Health Weekly Scan|PHGKB

Specific PHGKB|Reproductive and Child Health PHGKB|PHGKB

Specific PHGKB|HLBS|PHGKB-Heart Disease, Genomics and Precision Public Health

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Human Genes|COVID-19 GPH|PHGKB

The Current Landscape of CDC Publications in Human Genomics and Public Health | Blogs | CDC

Precision Public Health in Action: New CDC Pilot Projects Integrate Human Genomics into Public Health Surveillance and Applied Research | Blogs | CDC

sábado, 19 de febrero de 2022

Post–COVID Vaccine AHA Cases Raise Eyebrows in Italy

Be Wary of Influencers Giving Health, Fitness Advice: Experts

Don't Use 3 Recalled Baby Formulas, FDA Says

Subvariant May Be More Dangerous Than Omicron: Study

Confirmed: Cemiplimab Ups Survival in Recurrent Cervical Cancer

The Pandemic Isn’t Over for Immunocompromised People - The Atlantic

NIMH » Information Session: NIMH Intramural Research Program Training Opportunities

Herpes zoster related hospitalization after inactivated (CoronaVac) and mRNA (BNT162b2) SARS-CoV-2 vaccination: A self-controlled case series and nested case-control study - The Lancet Regional Health – Western Pacific

Herpes zoster related hospitalization after inactivated (CoronaVac) and mRNA (BNT162b2) SARS-CoV-2 vaccination: A self-controlled case series and nested case-control study - The Lancet Regional Health – Western Pacific

The allocation of COVID-19 vaccines and antivirals against emerging SARS-CoV-2 variants of concern in East Asia and Pacific region: A modelling study - The Lancet Regional Health – Western Pacific

Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics - eBioMedicine

Clinical predictors of acute cardiac injury and normalization of troponin after hospital discharge from COVID-19 - eBioMedicine

Long-term clinical outcomes of COVID-19 patients treated with imatinib - The Lancet Respiratory Medicine

Understanding how fast SARS-CoV-2 variants transmit from household studies - The Lancet Infectious Diseases

Time varying association between deprivation, ethnicity and SARS-CoV-2 infections in England: A population-based ecological study - The Lancet Regional Health – Europe

Elucidating the effect of geriatric parameters on COVID-19 outcomes for older adults with cancer - The Lancet Healthy Longevity

Geriatric risk factors for serious COVID-19 outcomes among older adults with cancer: a cohort study from the COVID-19 and Cancer Consortium - The Lancet Healthy Longevity

Fluvoxamine for the treatment of COVID-19 - The Lancet Global Health

Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review - The Lancet Global Health

Another piece in the COVID-19 treatment puzzle - The Lancet

Children, intersectionality, and COVID-19 - The Lancet

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial - The Lancet

Time varying association between deprivation, ethnicity and SARS-CoV-2 infections in England: A population-based ecological study - The Lancet Regional Health – Europe

The effect of social deprivation on the dynamic of SARS-CoV-2 infection in France: a population-based analysis - The Lancet Public Health

viernes, 18 de febrero de 2022

Statin Intolerance 'Overestimated and Overdiagnosed'

Epstein–Barr virus sparks brain autoimmunity in multiple sclerosis

Strong new evidence suggests a virus triggers multiple sclerosis - STAT

A Woman Is Cured of H.I.V. Using a Novel Treatment - The New York Times

COVID reinfections surge during Omicron onslaught

Changes in the brain cortex of COVID-19 patients associated with inflammatory biomarkers

Global cases are dropping, but the WHO is watching an Omicron subvariant | World News,The Indian Express

Messenger RNA can be used at low doses to regenerate bone without side effects

COVID-19 survivors more likely to suffer from mental health problems

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

Ensitrelvir, a novel SARS-CoV-2 antiviral

Trial of early antiviral therapy for COVID-19 shows no significant benefit

Study finds 'substantial decrease' in people's mental wellbeing since the start of the pandemic

Study to evaluate efficacy of higher dose of ivermectin for treating mild-to-moderate COVID-19

Covid-19 linked with an increased risk of mental health disorders, study finds

Advanced imaging reveals the loss of brain synapses in patients with mild symptoms of Alzheimer's

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Advancing Heart, Lung, Blood, and Sleep Research | NHLBI, NIH

Guest post: Joining forces to combat the COVID-19 mental health crisis

Scientists pinpoint mechanisms associated with severe COVID-19 blood clotting | National Institutes of Health (NIH)

Dimethyl Sulfoxide (DMSO) and Methylsulfonylmethane (MSM) for Osteoarthritis | NCCIH

Removing Naive T Cells May Prevent Chronic GVHD - National Cancer Institute

COVID-19: nocebo responses account for 76% of systemic AEs following vaccination

COVID-19 Around the world weekly highlights: the end of all restrictions in UK, Winter Olympics, and vaccination for children and teenagers…

COVID-19: long COVID risk factors identified, some treatable

Breakthrough COVID-19 in patients with rheumatic diseases

NIH’s Dr. Carl Dieffenbach Discusses Highlights of HIV Cure, Treatment and Prevention Research from CROI 2022 | HIV.gov

What's New in the Guidelines | NIH

FDA approves treatment for anemia in adults with rare inherited disorder | FDA

jueves, 17 de febrero de 2022

Combination Antidepressant Treatment Outperforms Monotherapy

Women at Higher Risk of Serious Adverse Events From Cancer Therapy

Antibodies perform best after Covid infection, not vaccine - ISRAEL21c

Brain activity in sleep and anesthesia clue to Alzheimer's - ISRAEL21c

Study: Women report Covid jab side effects more than men - ISRAEL21c

The Lancet Specialty Collections: Cardiology and Vascular Medicine

Prioritizing pain research in 2022 | National Institute on Aging

COVID-19 Informes Científicos CHEQUEADOS COMPLETOS REVISADOS (full texts)

Though rare, Moderna Covid vaccine recipients have higher risk of heart inflammation than Pfizer

Long covid in children and adolescents | The BMJ

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial | Critical Care Medicine | JAMA | JAMA Network

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial | Critical Care Medicine | JAMA | JAMA Network

Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review - Clinical Microbiology and Infection

Audio Interview: Covid-19 as an Endemic Disease | NEJM

Uterine Sarcoma Treatment (PDQ®)–Health Professional Version - National Cancer Institute

Stomach (Gastric) Cancer Prevention (PDQ®)–Health Professional Version - National Cancer Institute

Pediatric Allogeneic Hematopoietic Stem Cell Transplantation (PDQ®)–Health Professional Version - National Cancer Institute

Non-Small Cell Lung Cancer Treatment (PDQ®)–Health Professional Version - National Cancer Institute

Genetics of Breast and Gynecologic Cancers (PDQ®)–Health Professional Version - National Cancer Institute

Complications, Graft-Versus-Host Disease, and Late Effects After Pediatric Hematopoietic Stem Cell Transplantation (PDQ®)–Health Professional Version - National Cancer Institute

Childhood Hodgkin Lymphoma Treatment (PDQ®)–Health Professional Version - National Cancer Institute

Childhood Cancer Genomics (PDQ®)–Health Professional Version - National Cancer Institute

Cervical Cancer Prevention (PDQ®)–Health Professional Version - National Cancer Institute

Breast Cancer Screening (PDQ®)–Health Professional Version - National Cancer Institute

National Science Advisory Board for Biosecurity to convene | National Institutes of Health (NIH)

Tobacco Ban | Immunotherapy | Screening & Prevention, 02/16/2022

miércoles, 16 de febrero de 2022

Long COVID Symptoms Linked to Effects on Vagus Nerve

Scientists See Hope in New Therapy for COVID Brain Fog Patients

Researchers Document Third Known Case of HIV Remission Involving Stem Cell Transplant | HIV.gov

Omicron-targeted vaccines do no better than original jabs in early tests

List of the latest marketing authorisations and orphan medicinal products designations | www.eurordis.org

Dravet Syndrome Conference 2022 - Family and Scientific Days | Fundación Síndrome de Dravet

Rare Diseases - A Global Priority for Equity

Ministerial Conference on Research and Care Pathways: For a European policy on rare diseases - French Presidency of the Council of the European Union 2022

Science and Innovation Panel | IHI Innovative Health Initiative

EURORDIS announced the recipients of the 2022 Black Pearl Awards - EURORDIS - The Voice of Rare Disease Patients in Europe

EURORDIS - The Voice of Rare Disease Patients in Europe

Posters - ECRD2022

Downloads – Rare Disease Day 2022

Establishing an international cooperation - EURORDIS Open Academy

General discussion: Updates

Rare Diseases in the global spotlight on 28 February - EURORDIS - The Voice of Rare Disease Patients in Europe

EURORDIS - The Voice of Rare Disease Patients in Europe

Fact Sheet for Patients, Parents and Caregivers Emergency Use Authorization (EUA) of Bebtelovimab for Coronavirus Disease 2019 (COVID-19)

Frequently Asked Questions on the Emergency Use Authorization of Bebtelovimab for the Treatment of COVID-19

Fact Sheet for Healthcare Providers: Emergency Use Authorization for Bebtelovimab

Coronavirus (COVID-19) Update: FDA Authorizes New Monoclonal Antibody for Treatment of COVID-19 that Retains Activity Against Omicron Variant | FDA

Organisers - The Lancet Summit: HIV and Healthy Longevity, March 17-18, 2022 | Online and On-Demand

Identifying immune cells for personalized cancer immunotherapy | National Institutes of Health (NIH)

Poverty reduction alters infant brain activity | National Institutes of Health (NIH)

COVID-19 vaccines induce immune response to Omicron | National Institutes of Health (NIH)

Researchers document third known case of HIV remission involving stem cell transplant | National Institutes of Health (NIH)

A New Class of Immunomodulatory Drugs for Multiple Sclerosis | Technology Transfer

martes, 15 de febrero de 2022

Scientists identify potential reasons for COVID-19 vaccine hesitancy in US among individuals with chronic health conditions

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

Study describes sequelae presenting more than six months after COVID-19 in non-hospitalized young adults

Analysis of Death Records Shows Growing Disparities in Opioid Epidemic – NIH Director's Blog

ILAE Offers First Guide to Treating Depression in Epilepsy

Is Mild Cognitive Impairment Reversible?

Estrogen Replacement May Reduce COVID-19 Death Risk

US Underuse of GLP-1RA, SGLT-2i in Type 2 Diabetes Persists

COVID-19: ethnic minority groups with obesity at risk for severe illness, death

Moderate-vigorous stepping seen to lower diabetes risk in older women

Breakthrough COVID-19 in patients with rheumatic diseases

COVID-19: long COVID risk factors identified, some treatable

Type 2 diabetes drugs may work for primary CVD prevention

International Childhood Cancer Day 2022: Ways to take care of a child’s mental health during treatment | Lifestyle News,The Indian Express

What is Lassa fever?

lunes, 14 de febrero de 2022

Researchers identify autoantibody targets in COVID-19 patients

Study shows expression of viral proteases may be used to quantitate SARS-CoV-2 infected cells

Study explores the social impact of COVID-19 symptoms among female long haulers

Physicists investigate the usefulness of gene expression tests for cancer therapy

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

Medications, measurements of physical function could predict fall and fracture risk in older women

Differences in infection with Omicron or Delta SARS-CoV-2 variants among vaccinated population from the UK

Study demonstrates associations between COVID-19 symptom presentation and antibody assay reactivity

Study explores the gut microbiome of COVID-19 patients

Study examines the viral dynamics of Hong Kong's four SARS-CoV-2 waves

Improving function prediction by considering proteins in terms of their constituent domains - BMC Series blog

BMC Immunology | Home page

BMC Cancer | Home page

Behavioral and Brain Functions | Home page

Alzheimer's Research & Therapy | Home page

Acta Neuropathologica Communications | Home page

Orphanet Journal of Rare Diseases | Home page

The Lancet Oncology - Journal - Elsevier

domingo, 13 de febrero de 2022

Association of the Gut Microbiota With Cognitive Function in Midlife K Meyer et al, JAMA Network Open, February 8, 2022

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Causative Variants for Inherited Cardiac Conditions in a Southeast Asian Population Cohort. Tomar Swati et al. Circulation. Genomic and precision medicine 2022 CIRCGEN121003536

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Accounting for age of onset and family history improves power in genome-wide association studies. Pedersen Emil M et al. American journal of human genetics 2022 2

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The promise and pitfalls of gene testing for cancer risk J Madhusoodanan, Nature, December 2021

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Early prediction of preeclampsia in pregnancy with cell-free RNA MN Moufaraj et al, Nature, February 9, 2022

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Whole genome sequencing-based classification of human-related Haemophilus species and detection of antimicrobial resistance genes M Diricks et al, Genome Medicine, February 9, 2022

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Cardiovascular Signatures of COVID-19 Predict Mortality and Identify Barrier Stabilizing Therapies D Gustafson et al, MEDRXIV, February 9, 2022

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CDC-Authored Publications Update|PHGKB

Precision Health Database| Non-Genomics Precision Health Weekly Scan|PHGKB

Advanced Molecular Detection Clips Database|AMD Clips|PHGKB

Precision Health Database| Genomics Precision Health Weekly Scan|PHGKB

Progress in Genomic Medicine Implementation: Research Priorities and Population Health Impact | CDC

COVID-19 | Blogs | CDC

Specific PHGKB|Cancer|PHGKB

Heart Disease, Family Health History, and Familial Hypercholesterolemia | CDC

sábado, 12 de febrero de 2022

Predictors of uncertainty and unwillingness to receive the COVID-19 booster vaccine: An observational study of 22,139 fully vaccinated adults in the UK - The Lancet Regional Health – Europe

The Vaccinated and unvaccinated need to coexist with tolerance and respect - The Lancet Regional Health – Europe

SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network - eBioMedicine

COVID-19 vaccine perceptions and uptake: results from the COVID-19 Global Rheumatology Alliance Vaccine Survey - The Lancet Rheumatology

COVID-19 vaccine acceptance over time in patients with immune-mediated inflammatory rheumatic diseases - The Lancet Rheumatology

Future pandemics: failing to prepare means preparing to fail - The Lancet Respiratory Medicine

Convalescent plasma in outpatients with COVID-19 - The Lancet Respiratory Medicine

High-titre methylene blue-treated convalescent plasma as an early treatment for outpatients with COVID-19: a randomised, placebo-controlled trial - The Lancet Respiratory Medicine

Learning from the initial deployment of digital contact tracing apps - The Lancet Public Health

Effectiveness evaluation of digital contact tracing for COVID-19 in New South Wales, Australia - The Lancet Public Health

Comparison of SARS-CoV-2 anti-spike receptor binding domain IgG antibody responses after CoronaVac, BNT162b2, ChAdOx1 COVID-19 vaccines, and a single booster dose: a prospective, longitudinal population-based study - The Lancet Microbe

Comparison of SARS-CoV-2 anti-spike receptor binding domain IgG antibody responses after CoronaVac, BNT162b2, ChAdOx1 COVID-19 vaccines, and a single booster dose: a prospective, longitudinal population-based study - The Lancet Microbe

Safety and immunogenicity of two recombinant DNA COVID-19 vaccines containing the coding regions of the spike or spike and nucleocapsid proteins: an interim analysis of two open-label, non-randomised, phase 1 trials in healthy adults - The Lancet Microbe

Safety and immunogenicity of two recombinant DNA COVID-19 vaccines containing the coding regions of the spike or spike and nucleocapsid proteins: an interim analysis of two open-label, non-randomised, phase 1 trials in healthy adults - The Lancet Microbe

Transitioning to endemicity with COVID-19 research - The Lancet Infectious Diseases

Assessing the impact of the pandemic in children and adolescents: SARS-CoV-2 infection and beyond - The Lancet Child & Adolescent Health

Long COVID symptoms in SARS-CoV-2-positive adolescents and matched controls (LongCOVIDKidsDK): a national, cross-sectional study - The Lancet Child & Adolescent Health

Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England (CLoCk): a national matched cohort study - The Lancet Child & Adolescent Health

Risk of infection, hospitalisation, and death up to 9 months after a second dose of COVID-19 vaccine: a retrospective, total population cohort study in Sweden - The Lancet

Heart-disease risk soars after COVID — even with a mild case

Deaths of despair: impact of community support

Opioid overdose: risk factors among first-time users identified

Are European physicians following ESC/EASD guidelines?

Pediatric concussion: early return to activity safe, possibly beneficial

Research identifies new genetic risk factors for migraine

Coronavirus (COVID-19) Update: FDA Authorizes New Monoclonal Antibody for Treatment of COVID-19 that Retains Activity Against Omicron Variant | FDA

viernes, 11 de febrero de 2022

The COVID-19 Pandemic: What have the experts learned?

SARS-CoV-2 nucleocapsid G215C variation may explain Delta severity

Healthcare During The Climate Crisis

The Health Risks of Oversleeping

What are Viral Clades?

Showcasing STEM Women in Medical Science

Study suggests SARS-CoV-2 Omicron showed increased household transmission and immune evasion in Norway

New analysis highlights growing trends in combination cancer therapy clinical trials

Study identifies SARS-CoV-2 variants with potential to escape the immune system's T cell response

Unavailability of COVID-19 testing linked to greater intentions to engage in risky behavior

New protocol for transplanting 3D cellular structures to regenerate damaged intestinal tissue

Gene variants associated with acute kidney injury in Black veterans hospitalized with COVID-19

Drugs used to increase insulin signaling may be effective therapeutic strategy for autism

Molecular treatment works against metastatic cancer that spread to the brain

Scientific statement highlights the uncertainty about health effects of marijuana

New COVID-19 test can determine if individuals have been vaccinated, infected, both, or neither

Study investigates population immunity to SARS-CoV-2 through heterogenous pathways

Durvalumab Improves Survival in Bile Duct Cancers - National Cancer Institute

COVID-19 vaccines after previous SARS-CoV-1 infection

COVID-19: nocebo responses account for 76% of systemic AEs following vaccination

New metabolic phenotype of long COVID identified

COVID-19: preprint data suggest 2-dose vaccination offers protection against long-COVID symptoms

COVID-19: booster increases disease protection in the elderly

Public Meeting: FDA Rare Disease Day 2022 - 03/04/2022 | FDA

jueves, 10 de febrero de 2022

Breast Cancer | Teen Dating Violence | Quitting Cigarettes | DASH Eating Plan | Oral Health Report

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