CIENCIASMEDICASNEWS: diciembre 2023

Thank you to everyone who reads me, silently... thanks to everyone who follows me every day... thanks to all countries... Estados Unidos Suecia Alemania Singapur Reino Unido Corea del Sur Irán Francia Hong Kong Camboya Canadá Finlandia España Australia Colombia Afganistán Irlanda Rusia China Otros

Light Activity in Childhood May Lower Cholesterol Antara Ghosh

https://www.medscape.com/viewarticle/light-activity-childhood-may-lower-cholesterol-2023a1000wyu?src=

Short Course of Amoxicillin Shows Effectiveness for Febrile UTIs Heidi Splete

https://www.medscape.com/viewarticle/short-course-amoxicillin-shows-effectiveness-febrile-utis-2023a1000wyk?src=

Conjunctivitis: How Common Is It in Patients on Dupilumab for AD? Doug Brunk

https://www.medscape.com/s/viewarticle/conjunctivitis-how-common-patients-dupilumab-ad-2023a1000x0c?src=

Who Is Helped by AI Use During Colonoscopy? Marilynn Larkin

https://www.medscape.com/viewarticle/who-helped-ai-use-during-colonoscopy-2023a1000x0p?src=

Beetroot Juice Improves Fitness and Function in Patients With COPD Heidi Splete

https://www.medscape.com/viewarticle/beetroot-juice-improves-fitness-and-function-patients-copd-2023a1000wzt

New on NCI’s Websites for December 2023

https://www.cancer.gov/news-events/cancer-currents-blog/2023/new-online-december-2023?cid=eb_govdel W. Kimryn Rathmell Begins Work as 17th Director of the National Cancer Institute

New Findings About Key Pathological Protein in Parkinson’s Disease Open Paths to Novel Therapies

https://www.hopkinsmedicine.org/news/newsroom/news-releases/2023/12/new-findings-about-key-pathological-protein-in-parkinsons-disease-open-paths-to-novel-therapies

Don’t miss the National Eye Institute’s upcoming Visual NeuroPlasticity Workshop Wednesday, January 10, 2024,

https://braininitiative.nih.gov/news-events/blog/dont-miss-national-eye-institutes-upcoming-visual-neuroplasticity-workshop

U.S. - Ireland R&D Partnership hosts workshop

https://www.nei.nih.gov/about/news-and-events/news/us-ireland-rd-partnership-hosts-workshop

NEI posts executive summary of workshop on extracellular vesicles

https://www.nei.nih.gov/about/news-and-events/news/nei-posts-executive-summary-workshop-extracellular-vesicles

Study Identifies "Visual System" Protein for Circadian Rhythm Stability

https://www.hopkinsmedicine.org/news/newsroom/news-releases/2023/12/study-identifies-visual-system-protein-for-circadian-rhythm-stability

viernes, 29 de diciembre de 2023

Advanced MRI hopes to improve outcomes for Fontan cardiac patients

https://innovationdistrict.childrensnational.org/advanced-mri-hopes-to-improve-outcomes-for-fontan-cardiac-patients/

BLUE LIGHT EXPOSURE: UNVEILING THE EFFECTS

Blue Light Exposure: Unveiling the Effects By Ivanhoe Broadcast News on January 7, 2024 https://www.ivanhoe.com/?p=32112&preview=1&_ppp=95e6681095

ALEXANDRA’S ART FUNDS RESEARCH

Alexandra’s Art Funds Research By Ivanhoe Broadcast News on January 7, 2024 https://www.ivanhoe.com/?p=32109&preview=1&_ppp=c4e13945ce

SENIORS BATTLING ANXIETY IN SILENCE

Seniors Battling Anxiety in Silence By Ivanhoe Broadcast News on January 6, 2024 https://www.ivanhoe.com/?p=32106&preview=1&_ppp=516305e615

CHRONIC PAIN, INFLAMMATION AND DEMENTIA LINK

Chronic Pain, Inflammation and Dementia Link By Ivanhoe Broadcast News on January 6, 2024 https://www.ivanhoe.com/?p=32103&preview=1&_ppp=23b67735d7

HEALING TOOTHPASTE: HYDROXYAPATITE TO THE RESCUE

Healing Toothpaste: Hydroxyapatite to The Rescue By Ivanhoe Broadcast News on January 5, 2024 https://www.ivanhoe.com/?p=32100&preview=1&_ppp=405ac54d8f

NEW KIND OF CLASSROOM FOR SICK KIDS

New Kind of Classroom for Sick Kids By Ivanhoe Broadcast News on January 4, 2024 https://www.ivanhoe.com/?p=32097&preview=1&_ppp=1c485ef109

PLAN B FOR STATIN-INTOLERANT PATIENTS

Plan B for Statin-Intolerant Patients By Ivanhoe Broadcast News on January 3, 2024 https://www.ivanhoe.com/?p=32094&preview=1&_ppp=6e596c48d7

ARE NAPS REALLY BENEFICIAL?

Are Naps Really Beneficial? By Ivanhoe Broadcast News on January 2, 2024 https://www.ivanhoe.com/?p=32091&preview=1&_ppp=a6fbedc497

HOSPITAL TO HOME: NURSES HELP NAVIGATE THEIR PATIENTS’ RECOVERY

Hospital to Home: Nurses Help Navigate Their Patients’ Recovery By Ivanhoe Broadcast News on January 1, 2024 https://www.ivanhoe.com/?p=32088&preview=1&_ppp=84a1f596bc

Extracranial Surgery Soon After TBI Tied to Poorer Outcomes Kelli Whitlock Burton

https://www.medscape.com/viewarticle/extracranial-surgery-soon-after-tbi-tied-poorer-outcomes-2023a1000wvp?src=

tDCS Promising for Improved Cognition in Alzheimer's Megan Brooks

https://www.medscape.com/viewarticle/tdcspromising-improved-cognition-alzheimers-2023a1000wvt?src=

Sharp Rise in US Suicide Rates Especially in Indigenous People, White Men Eve Bender

https://www.medscape.com/viewarticle/sharp-rise-us-suicide-rates-especially-indigenous-people-2023a1000wvz?src=

No Added Benefit From Chemo in This Breast Cancer Subtype Liam Davenport

https://www.medscape.com/viewarticle/no-added-benefit-chemo-this-breast-cancer-subtype-2023a1000wwb?src=

Regular Physical Activity Linked to Larger Brain Volume Megan Brooks

https://www.medscape.com/viewarticle/regular-physical-activity-linked-larger-brain-volume-2023a1000wx3?src=

'World's Healthiest Arteries' Found to Be the Most Elastic Matías A. Loewy

https://www.medscape.com/viewarticle/worlds-healthiest-arteries-found-be-most-elastic-2023a1000wup

Specific Personality Traits May Influence Dementia Risk Megan Brooks

https://www.medscape.com/viewarticle/specific-personality-traits-may-influence-dementia-risk-2023a1000uyu?ecd=mkm_ret_231229_mscpmrk_neuro_dementia_etid6203395&uac=148436CN&impID=6203395

Neuroinflammation and Alzheimer's disease poster

https://www.abcam.com/neuroscience/neuroinflammation-and-alzheimers-disease-poster?utm_source=Eloqua&utm_medium=Email&utm_campaign=Neuroinflammation%7CEngage%7C2020-01-29%2019%3A00%3A00.000%7CN%2FA%7CGLOBAL%7CEN%7CAutomated%20-%20Research%20Area&mi_u=813661&yeti=gclid

Know the Science: Complementary and Integrative Health Resources From NCCIH

https://www.nccih.nih.gov/health/know-science?nav=govd Complementary and Integrative Health Resources From NCCIH https://www.nccih.nih.gov/health/atoz?nav=govd Herbs at a Glance https://www.nccih.nih.gov/health/herbsataglance?nav=govd Alerts and Advisories https://www.nccih.nih.gov/news/alerts?nav=govd Connect With Us: Email Updates and Social Media https://www.nccih.nih.gov/news/subscribe?nav=govd

Hypothermia | Home Test to Treat | Coal Pollution Deaths | Holiday Drinking | Mental Health Research

https://content.govdelivery.com/accounts/USNIH/bulletins/381d64e?reqfrom=share

jueves, 28 de diciembre de 2023

Post-conization surveillance in an organized cervical screening program with more than 23,000 years of follow-up

https://infectagentscancer.biomedcentral.com/

Experiences of patients and family members with follow-up care, information needs and provider support after identification of Lynch Syndrome

https://hccpjournal.biomedcentral.com/

The classification of obesity based on metabolic status redefines the readmission of non-Hodgkin’s lymphoma—an observational study

https://cancerandmetabolism.biomedcentral.com/

Association between allostatic load and breast cancer risk: a cohort study

https://breast-cancer-research.biomedcentral.com/

Orphanet Journal of Rare Diseases

https://ojrd.biomedcentral.com/

Highlights in HR-Positive Breast Cancer From SABCS 2023 Harold J. Burstein, MD, PhD

https://www.medscape.com/recap/982388?src=

Benzodiazepines Linked to Higher Miscarriage Risk in Early Pregnancy Lara Salahi

https://www.medscape.com/viewarticle/benzodiazepines-linked-higher-miscarriage-risk-early-2023a1000wtx?src=

Positive Topline Results for SEQUOIA-HCM Trial in OHCM Susan Jeffrey

https://www.medscape.com/viewarticle/positive-topline-results-sequoia-hcm-trial-ohcm-2023a1000wu9?src=

Elafibranor Appears Effective, Safe for Primary Biliary Cholangitis Carolyn Crist

https://www.medscape.com/viewarticle/elafibranor-appears-effective-safe-primary-biliary-2023a1000wud?src=

Building a Toolkit for the Treatment of Acute Migraine Sue Hughes

https://www.medscape.com/viewarticle/building-toolkit-treatment-acute-migraine-2023a1000wtz?src=

Complementary Psychological and/or Physical Approaches for Cancer Symptoms and Treatment Side Effects

https://www.nccih.nih.gov/health/providers/digest/mind-and-body-approaches-for-cancer-symptoms-and-treatment-side-effects

When and How To Contact NCCIH Program Directors for Help

https://www.nccih.nih.gov/research/blog/when-and-how-to-contact-nccih-program-directors-for-help?nav=govd

Don’t call me “old”: Avoiding ageism when writing about aging

https://www.nia.nih.gov/research/blog/2023/12/dont-call-me-old-avoiding-ageism-when-writing-about-aging?utm_source=NIA+Main&utm_campaign=0405749933-blog-ageist-language-12-27&utm_medium=email&utm_term=0_-8180ce9847-%5BLIST_EMAIL_ID%5D Ageist messages are everywhere — you need only to browse a greeting card aisle to see countless quips about being a “geezer” or “over the hill.” Ageist content is so prevalent in our society that too many people may not recognize it as problematic. Well-intentioned writers can sometimes inadvertently reinforce harmful stereotypes about older adults. Whether you’re writing a blog post, grant application, or journal article, here are some tips and resources to help your audience think more positively about aging.

In Mouse Study, KRAS-Targeted Drug Shows Potential against Pancreatic Cancer

https://www.cancer.gov/news-events/cancer-currents-blog/2023/pancreatic-cancer-kras-g12d-mrtx1133?cid=eb_govdel Progress continues in targeting a hard-to-hit cancer protein KRAS has been one of the most hard-to-hit targets in cancer research. But over the past 2 years, two new drugs, sotorasib (Lumakras) and adagrasib (Krazati), have been approved to treat people with non-small cell lung cancer that has the KRAS G12C mutation. This mutation occurs less frequently in other cancers and is only seen in about 1%–2% of pancreatic cancers. Even so, researchers have begun testing both drugs in small clinical trials of people with other cancers with KRAS G12C mutations. In a trial involving 38 patients with advanced pancreatic cancer, for example, sotorasib shrank tumors in about 20% of participants. Similar results were seen with adagrasib in a trial involving people with advanced colorectal cancer.v

miércoles, 27 de diciembre de 2023

Long COVID: New Info on Who Is Most Likely to Get It Solarina Ho

https://www.medscape.com/viewarticle/long-covid-new-info-who-most-likely-get-it-2023a1000wq4?src=

Chronic Lymphocytic Leukemia Highlights From ASH 2023 John Allan, MD

https://www.medscape.com/recap/987764?src=

The 2024 Adult Vaccine Schedule Changes Are Here Sandra Adamson Fryhofer, MD

https://www.medscape.com/viewarticle/999318?src=

Starting a Family in Med School Problematic, Say Students Carolyn Crist

https://www.medscape.com/viewarticle/starting-family-med-school-problematic-say-students-2023a1000wmn

FDA approves topical treatment for junctional, dystrophic epidermolysis bullosa Doug Brunk

https://www.medscape.com/s/viewarticle/fda-approves-topical-treatment-junctional-dystrophic-2023a1000wlt?ecd=wnl_edit_tpal_etid6196075&uac=148436CN&impID=6196075

EU Seeks to Reduce the Risks for Artificial Intelligence Ute Eppinger

https://www.medscape.com/viewarticle/eu-seeks-reduce-risks-artificial-intelligence-2023a1000wp7?src=

Death Risk Takes Decades to Revert to Normal in Ex-Smokers Jürgen Sartorius

https://www.medscape.com/viewarticle/death-risk-takes-decades-revert-normal-ex-smokers-2023a1000wql?src=

Predicting Immune-related Adverse Events from Checkpoint Inhibitors in Melanoma Helen Leask

https://www.medscape.com/viewarticle/predicting-immune-related-adverse-events-checkpoint-2023a1000wml?src=

Noninvasive Ultrasound Benefits Calcified Aortic Valves Anne-Gaëlle Moulun

https://www.medscape.com/viewarticle/noninvasive-ultrasound-benefits-calcified-aortic-valves-2023a1000wpb?src=

Device-Detected Atrial High-Rate Episodes Tied to Mortality Marilynn Larkin

https://www.medscape.com/viewarticle/device-detected-atrial-high-rate-episodes-tied-mortality-2023a1000wps?src=

Understanding the genetic basis of hereditary diffuse gastric cancer

https://www.news-medical.net/news/20231226/Understanding-the-genetic-basis-of-hereditary-diffuse-gastric-cancer.aspx

New model links RNA editing glitch to early-stage type 1 diabetes

https://www.news-medical.net/news/20231226/New-model-links-RNA-editing-glitch-to-early-stage-type-1-diabetes.aspx

Brain bleeds in older adults linked to amyloid deposits in blood vessels

https://www.news-medical.net/news/20231226/Brain-bleeds-in-older-adults-linked-to-amyloid-deposits-in-blood-vessels.aspx

New drug screening system helps uncover promising target for pancreatic cancer treatments

https://www.news-medical.net/news/20231226/New-drug-screening-system-helps-uncover-promising-target-for-pancreatic-cancer-treatments.aspx

‘Grief has no expiration date': Evidence shows youth gunshots increase mental health & drug disorders By Ted Oberg, News4 Investigative Reporter, Rick Yarborough, Steve Jones and Jeff Piper

https://www.nbcwashington.com/news/local/dc-gun-violence/grief-has-no-expiration-date-evidence-shows-youth-gunshots-increase-mental-health-and-drug-disorders/3469419/

Dear new parent: Daycare won’t screw up your baby. Allow the experts to explain why No, your kid will not think you abandoned them.

https://www.today.com/parents/family/is-daycare-bad-infants-toddlers-experts-explain-rcna122096

Addiction treatment for kids and teenagers lags far behind demand

https://www.axios.com/2023/10/24/children-fentanyl-addiction-treatment

Survey: Teen parents with support report greater well-being

https://innovationdistrict.childrensnational.org/teen-parents-with-support-report-greater-well-being/

CN-NIAID Symposium seeks ways to promote child health amid challenges

https://innovationdistrict.childrensnational.org/cn-niaid-symposium-seeks-ways-to-promote-child-health-amid-challenges/

Using a multisystem approach to improve access to autism care in Washington, D.C.

https://innovationdistrict.childrensnational.org/using-a-multisystem-approach-to-improve-access-to-autism-care-in-washington-d-c/

martes, 26 de diciembre de 2023

TOPS FUSION ALTERNATIVE

TOPS Fusion Alternative By Ivanhoe Broadcast News on December 25, 2023 https://www.ivanhoe.com/medical-breakthroughs/tops-fusion-alternative/

GENE THERAPY: REDEFINING HEMOPHILIA TREATMENT

Gene Therapy: Redefining Hemophilia Treatment By Ivanhoe Broadcast News on December 26, 2023 https://www.ivanhoe.com/medical-breakthroughs/gene-therapy-redefining-hemophilia-treatment/

THE HAMR FIGHTS CANCER

The HAMR Fights Cancer By Ivanhoe Broadcast News on December 27, 2023 https://www.ivanhoe.com/?p=32066&preview=1&_ppp=c21391aa54

ACCUCINCH HEALS HEARTS

AccuCinch Heals Hearts By Ivanhoe Broadcast News on December 28, 2023 https://www.ivanhoe.com/?p=32069&preview=1&_ppp=08e3153b5f

TOXIC VACATIONS: POISONED BY CARBON MONOXIDE

Toxic Vacations: Poisoned by Carbon Monoxide By Ivanhoe Broadcast News on December 29, 2023 https://www.ivanhoe.com/?p=32072&preview=1&_ppp=6500216f10

THE MORNING AFTER: HANGOVER CURES THAT WORK

The Morning After: Hangover Cures That Work By Ivanhoe Broadcast News on December 31, 2023 https://www.ivanhoe.com/?p=32053&preview=1&_ppp=02ab77cc75

FRESH START: EATING YOUR WAY TO BETTER HEALTH IN 2024

Fresh Start: Eating Your Way to Better Health In 2024 By Ivanhoe Broadcast News on December 30, 2023 https://www.ivanhoe.com/?p=32050&preview=1&_ppp=4fc6325863

OFFICE TIME-SUCKS: HOW TO OVERCOME PRODUCTIVITY PITFALLS

Office Time-Sucks: How to Overcome Productivity Pitfalls By Ivanhoe Broadcast News on December 30, 2023 https://www.ivanhoe.com/?p=32047&preview=1&_ppp=01a96d92a9

TRAUMA CENTER FOR SURVIVORS, RESPONDERS OF OCT. 7 MASSACRE Two Israeli organizations partner in Ra’anan Safe Space, a place in nature fostering resilience and healing.

https://www.israel21c.org/trauma-center-for-survivors-responders-of-oct-7-massacre/

THE HEARING AID HIDDEN IN YOUR GLASSES Nuance Hearing working with global eyewear giant to make efficient and economic hearing aids that fit invisibly into your glasses.

https://www.israel21c.org/startup-develops-innovative-hearing-aid-hidden-in-glasses-frame/

Citrus supplement may ease knee swelling and pain after surgery

https://www.news-medical.net/news/20231222/Citrus-supplement-may-ease-knee-swelling-and-pain-after-surgery.aspx

MIT engineers develop 'vibing belly' pill to control appetite and curb obesity

https://www.news-medical.net/news/20231226/MIT-engineers-develop-vibing-belly-pill-to-control-appetite-and-curb-obesity.aspx

Common stomach bacteria may be linked to higher risk of Alzheimer's disease

https://www.news-medical.net/news/20231226/Common-stomach-bacteria-may-be-linked-to-higher-risk-of-Alzheimers-disease.aspx

Shedding new light on the evolution of tuberculosis

https://www.news-medical.net/news/20231226/Shedding-new-light-on-the-evolution-of-tuberculosis.aspx

Study: Cuddling during sleep comes at a cost, even for mice

https://www.news-medical.net/news/20231226/Study-Cuddling-during-sleep-comes-at-a-cost-even-for-mice.aspx

Biomarker Research: Neoantigen-targeted TCR-engineered T cell immunotherapy: current advances and challenges

https://biomarkerres.biomedcentral.com/

The brain-liver cholinergic anti-inflammatory pathway and viral infections

https://bioelecmed.biomedcentral.com/

Univariate and multivariate sex differences and similarities in gray matter volume within essential language-processing areas

https://bsd.biomedcentral.com/

Sex differences in the human brain: a roadmap for more careful analysis and interpretation of a biological reality

https://bsd.biomedcentral.com/articles/10.1186/s13293-022-00448-w

Behavioral and Brain Functions: Specific brain imaging alterations underlying autistic traits in children with attention-deficit/hyperactivity disorder

https://behavioralandbrainfunctions.biomedcentral.com/

Alzheimer's Research & Therapy: Statins and cognitive decline in patients with Alzheimer’s and mixed dementia: a longitudinal registry-based cohort study

https://alzres.biomedcentral.com/

Orphanet Journal of Rare Diseases: Experience of life quality from patients with aplastic anemia: a descriptive qualitative study

https://ojrd.biomedcentral.com/articles/10.1186/s13023-023-02993-y The official journal of Orphanet, the portal for rare diseases and orphan drugs. https://ojrd.biomedcentral.com/

LSU Health discovery may open new therapeutic avenues for degenerative diseases of the brain and eye

https://www.nei.nih.gov/about/news-and-events/news/lsu-health-discovery-may-open-new-therapeutic-avenues-degenerative-diseases-brain-and-eye NEI Research News https://www.nei.nih.gov/about/news-and-events/news

lunes, 25 de diciembre de 2023

How Surgeons Used a Double-Lung Transplant and a Pair of Breast Implants to Save a Young Man's Life F. Perry Wilson, MD, MSCE

https://www.medscape.com/viewarticle/998467?src=

Technology for Primary Care — Terrific, Terrifying, or Both? Barbara J. Howard, MD

https://www.medscape.com/s/viewarticle/999320?src=

Improving the Treatment of Sexual Dysfunction in Women Aude Lecrubier

https://www.medscape.com/viewarticle/improving-treatment-sexual-dysfunction-women-2023a1000wf2?src=

Monoclonal Antibodies: A New Treatment for Long COVID? Hallie Levine

https://www.medscape.com/viewarticle/monoclonal-antibodies-new-treatment-long-covid-2023a1000wfa

Walking Fast May Help Prevent Type 2 Diabetes Dominique Baudon

https://www.medscape.com/viewarticle/walking-fast-may-help-prevent-type-2-diabetes-2023a1000wey

domingo, 24 de diciembre de 2023

Impact of an antibiotic stewardship initiative on urgent-care respiratory prescribing across patient race, ethnicity, and language

https://phgkb.cdc.gov/PHGKB/cdcSCStartPage.action

Family Health History

https://www.cdc.gov/genomics/famhistory/index.htm

Putting everything in its place: using the INSDC compliant Pathogen Data Object Model to better structure genomic data submitted for public health applications

https://phgkb.cdc.gov/PHGKB/cdcPubFinder.action?Mysubmit=update

LETHE: A Digital Intervention for Cognitive Decline. Vasileios S Loukas et al. Annu Int Conf IEEE Eng Med Biol Soc 2023 20231-4

https://phgkb.cdc.gov/PHGKB/translationClip.action?action=nonGhome

The clinical and epidemiological impacts of whole genomic sequencing on bacterial and virological agents. Sarah Timsit et al. Infect Dis Now 2023 12 104844

https://phgkb.cdc.gov/PHGKB/amdClip.action?action=home

HER2/ERBB2 copy number analysis by targeted next-generation sequencing in breast cancer. Daniel Xia et al. Am J Clin Pathol 2023

https://phgkb.cdc.gov/PHGKB/translationClip.action?action=home

The infant gut virome is associated with preschool asthma risk independently of bacteria CL Rodriguez et al, Nature Medicine, December 15, 2023

https://phgkb.cdc.gov/PHGKB/phgHome.action?action=archive&date=12/15/2023 From the abstract: "Here, we analyze the gut virome of 647 children aged 1?year from the Copenhagen Prospective Studies on Asthma in Childhood2010 (COPSAC2010) mother–child cohort, all deeply phenotyped from birth and with longitudinally assessed asthma diagnoses. Specific temperate gut phage taxa were found to be associated with later development of asthma. In particular, the joint abundances of 19 caudoviral families were found to significantly contribute to this association. Combining the asthma-associated virome and bacteriome signatures had additive effects on asthma risk."

How Family History Influences Your Drinking DG Smith, NY Times, December 13, 2023

https://phgkb.cdc.gov/PHGKB/phgHome.action?action=archive&date=12/17/2023 From the article: " Alcohol use disorder — the inability to stop or control one’s drinking despite negative consequences — is a highly heritable condition. Research suggests that having an immediate family member, like a parent or sibling, with the disorder increases an individual’s chances of developing it roughly three- to fourfold. Approximately 50 percent of a person’s risk comes from their genes, but their home and social environments are also important factors."

Direct to Consumer Biomarker Testing for Alzheimer Disease—Are We Ready for the Insurance Consequences? JJ Arias et al, JAMA Neurology, December 18, 2023

https://phgkb.cdc.gov/PHGKB/phgHome.action?action=archive&date=12/18/2023 From the article: "The promise of DTC testing for AD biomarkers may be lauded by advocates pushing for earlier diagnoses and individuals’ right to know. Early diagnosis of AD through DTC or clinical evaluations could provide benefits, including increased monitoring and preventive care. Additionally, DTC tests could reduce barriers that impede a timely diagnosis (eg, access to dementia specialists). However, DTC tests are not without hazard, particularly given gaps in discriminatory protections for individuals at risk of developing AD with known biomarker status. "

Systematic review and meta-analysis of AI-based conversational agents for promoting mental health and well-being H Li, NPJ Digital Medicine, December 19, 2023

https://phgkb.cdc.gov/PHGKB/phgHome.action?action=archive&date=12/20/2023 From the abstract: "Conversational artificial intelligence (AI), particularly AI-based conversational agents (CAs), is gaining traction in mental health care. Despite their growing usage, there is a scarcity of comprehensive evaluations of their impact on mental health and well-being. This systematic review and meta-analysis aims to fill this gap by synthesizing evidence on the effectiveness of AI-based CAs in improving mental health and factors influencing their effectiveness and user experience. "

Using genomics to track malaria in the US T Locke, MedicalXpress, December 20, 2023

https://phgkb.cdc.gov/PHGKB/phgHome.action?action=all%20hot%20topics From the website: "Both the parasite genome and the mosquito genome are very important because each of those represents a unique fingerprint. You can characterize the disease that's caused by that particular parasite and also track the parasites and the mosquitoes. Malaria parasites, for example, in parts of Ethiopia or India are different from each other, but those malaria parasites in India are similar to each other. If you don't know the origin of a malaria parasite, you can track it back to where it might have come from by comparing it with lots of different genomes of malaria parasites throughout the endemic world. "

sábado, 23 de diciembre de 2023

Publications about Seasonal Affective Disorder (SAD)

https://www.nimh.nih.gov/health/publications/seasonal-affective-disorder-listing

Age disparities in glucose-lowering treatment for Danish people with type 2 diabetes: a cross-sectional study between 2019 and 2020 Johansson et al.

https://www.thelancet.com/journals/lanhl/home

The Lancet Gastroenterology & Hepatology in conversation with Sarah Moen on metachronous colorectal cancer risk according to Lynch syndrome pathogenic variant after colectomy

https://thelancetgastrohep.buzzsprout.com/1728646/14056722-sarah-moen-on-metachronous-colorectal-cancer-risk-according-to-lynch-syndrome-pathogenic-variant-after-colectomy?utm_campaign=update-langas&utm_medium=email&_hsmi=287127807&_hsenc=p2ANqtz-_SnAjp3LBxBfN93-4yrSqvMJoXIHSUWpNSFhZyxu830pCkryewQnUfF8K036dP4bLbP0ns0sp-68HHMT3SVLABh4i4cQ&utm_content=287072615&utm_source=hs_email

Implementation of a liver health check in people with type 2 diabetes

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00270-4/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsmi=287127807&_hsenc=p2ANqtz--Up8H7oer57LYMD9BUAtMNdGPUa7OJqFx94fuIFy5p8VfDyO3MtLs4pBzQu_7cFhiROyNM6ajhYm3W6yWiBI8Nk_UccA&utm_content=287072615&utm_source=hs_email

Primary antibiotic resistance of Helicobacter pylori in the Asia-Pacific region between 1990 and 2022: an updated systematic review and meta-analysis

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00281-9/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsmi=287127807&_hsenc=p2ANqtz--IABx5IuT2GUkiJbIk538iw6jh7w_Z2VJIBwqWXRHTPzapuS3iTixFiMMkZvY5g73-g4qTnZZ-F5LntOfqD-dQUwSrWA&utm_content=287072615&utm_source=hs_email

Upfront necrosectomy for infected necrotising pancreatitis: a promising strategy? Deepak Gunjan,Soumya Jagannath Mahapatra,Pramod Kumar Garg

https://www.thelancet.com/journals/langas/issue/vol9no1/PIIS2468-1253(23)X0012-0

Effect of an artificial intelligence-assisted system on endoscopic diagnosis of superficial oesophageal squamous cell carcinoma and precancerous lesions: a multicentre, tandem, double-blind, randomised controlled trial

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00276-5/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsmi=287127807&_hsenc=p2ANqtz--RGfJ1RjxWVjjWYZXz64XQ0iehBnBaUL0vqJauwU2wCIYUrehhHd_JIisUo9bu_hnAzCvYHWat5b9FqCs9r-VVHBJLSQ&utm_content=287072615&utm_source=hs_email

Genetic Signature May Help Tailor Treatment for Meningioma

https://www.cancer.gov/news-events/cancer-currents-blog/2023/meningioma-gene-expression-signature?cid=eb_govdel

Red Clover

https://www.nccih.nih.gov/health/red-clover?nav=govd

Following Abnormal Cancer Screening Results, Multi-Level Reminders May Increase Follow-Up

https://www.cancer.gov/news-events/cancer-currents-blog/2023/cancer-screening-reminders-improve-follow-up?cid=eb_govdel

Microplastics as pathogen carriers in water pose environmental and public health risks

https://www.news-medical.net/news/20231222/Microplastics-as-pathogen-carriers-in-water-pose-environmental-and-public-health-risks.aspx

Study: Traditional CBT as effective as exposure therapy for fibromyalgia

https://www.news-medical.net/news/20231222/Study-Traditional-CBT-as-effective-as-exposure-therapy-for-fibromyalgia.aspx

3D-printed bone: Biomimetic scaffolds offer hope for cranial defect repair

https://www.news-medical.net/news/20231222/3D-printed-bone-Biomimetic-scaffolds-offer-hope-for-cranial-defect-repair.aspx

Microglia found to play a key role in regulating the body's response to anesthesia

https://www.news-medical.net/news/20231222/Microglia-found-to-play-a-key-role-in-regulating-the-bodys-response-to-anesthesia.aspx

Sales of emergency contraception estimated to rise after the New Year holiday

https://www.news-medical.net/news/20231222/Sales-of-emergency-contraception-estimated-to-rise-after-the-New-Year-holiday.aspx

viernes, 22 de diciembre de 2023

New NIH MedlinePlus Magazine Now Available

https://magazine.medlineplus.gov/pdf/Volume18_Issue4-508C-small.pdf

Taking on the stigma of ADHD 'The Amazing Race' winner Penn Holderness explains how his mind works in unique ways

https://magazine.medlineplus.gov/article/taking-on-the-stigma-of-adhd

Ask an Expert: Marishka K. Brown, Ph.D., Director of the National Center on Sleep Disorders Research

https://magazine.medlineplus.gov/article/ask-an-expert-marishka-k-brown-ph.d-director-of-the-national-center-on-sleep-disorders-research?utm_medium=email&utm_source=govdelivery

2023 NIH Research Highlights - Basic Research Insights

https://www.nih.gov/news-events/nih-research-matters/2023-nih-research-highlights-basic-research-insights

2023 NIH Research Highlights - Promising Medical Findings

https://www.nih.gov/news-events/nih-research-matters/2023-nih-research-highlights-promising-medical-findings

2023 NIH Research Highlights - Human Health Advances

https://www.nih.gov/news-events/nih-research-matters/2023-nih-research-highlights-human-health-advances

Sleep loss linked to reduced positivity and heightened anxiety

https://www.news-medical.net/news/20231221/Sleep-loss-linked-to-reduced-positivity-and-heightened-anxiety.aspx

Groundbreaking treatment tool being developed for male breast cancer diagnosis

https://www.news-medical.net/news/20231221/Groundbreaking-treatment-tool-being-developed-for-male-breast-cancer-diagnosis.aspx

Study highlights underutilization of end-of-life care for patients with malignant urinary obstruction

https://www.news-medical.net/news/20231221/Study-highlights-underutilization-of-end-of-life-care-for-patients-with-malignant-urinary-obstruction.aspx

Sniffing women’s tears could be the key to taming male aggression

https://www.news-medical.net/news/20231221/Sniffing-womene28099s-tears-could-be-the-key-to-taming-male-aggression.aspx

Study reveals how measles virus mutates and spreads in the human brain

https://www.news-medical.net/news/20231221/Study-reveals-how-measles-virus-mutates-and-spreads-in-the-human-brain.aspx

Previously unrecognized class of antibodies can broadly neutralize multiple virus strains

https://www.news-medical.net/news/20231221/Previously-unrecognized-class-of-antibodies-can-broadly-neutralize-multiple-virus-strains.aspx

Microplastics as pathogen carriers in water pose environmental and public health risks

https://www.news-medical.net/news/20231222/Microplastics-as-pathogen-carriers-in-water-pose-environmental-and-public-health-risks.aspx

Study: Traditional CBT as effective as exposure therapy for fibromyalgia

https://www.news-medical.net/news/20231222/Study-Traditional-CBT-as-effective-as-exposure-therapy-for-fibromyalgia.aspx

University of Michigan project seeks to improve control of robotic prosthetic legs

https://www.news-medical.net/news/20231221/University-of-Michigan-project-seeks-to-improve-control-of-robotic-prosthetic-legs.aspx

Orphanet Journal of Rare Diseases: Experience of life quality from patients with aplastic anemia: a descriptive qualitative studyv

https://ojrd.biomedcentral.com/

jueves, 21 de diciembre de 2023

What Is Frontotemporal Dementia?

An implantable device could pave the way for continuous, injection-free diabetes treatment

https://www.nibib.nih.gov/news-events/newsroom/implantable-device-could-pave-way-continuous-injection-free-diabetes-treatment

Statement: Antibody Reduces Allergic Reactions to Multiple Foods in NIH Trial

https://www.niaid.nih.gov/news-events/antibody-reduces-allergic-reactions-multiple-foods-nih-trial?utm_campaign=+58760368&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

Antibody reduces allergic reactions to multiple foods in NIH trial

https://www.nih.gov/news-events/news-releases/antibody-reduces-allergic-reactions-multiple-foods-nih-trial

The Ups and Downs of Bipolar Disorder

https://www.nimh.nih.gov/news/science-news/2023/the-ups-and-downs-of-bipolar-disorder?utm_campaign=75&utm_medium=email&utm_source=govd

Fatigue | Mind-Body | Precision Medicine Trials, 12/18/2023

https://content.govdelivery.com/accounts/USNIHNCI/bulletins/380c2b7?reqfrom=share

Phone-based Dementia Caregiver Education Program for Latino Families

https://www.alzheimers.gov/clinical-trials/phone-based-dementia-caregiver-education-program-latino-families?utm_source=nia-eblast&utm_medium=email&utm_campaign=clinicaltrials-20231220 Start: May 1, 2022 End: Jan. 31, 2025 Enrollment: 100

Mobile Health Application To Reduce Caregiver Burden in Hispanic Dementia Caregivers

https://www.alzheimers.gov/clinical-trials/mobile-health-application-reduce-caregiver-burden-hispanic-dementia-caregivers?utm_source=nia-eblast&utm_medium=email&utm_campaign=clinicaltrials-20231220 Start: Sept. 26, 2023 End: September 2025 Enrollment: 40

Emergency Preparedness Program for Dementia Caregivers

https://www.alzheimers.gov/clinical-trials/emergency-preparedness-program-dementia-caregivers?utm_source=nia-eblast&utm_medium=email&utm_campaign=clinicaltrials-20231220 Start: July 12, 2023 End: June 30, 2027 Enrollment: 200

KarXT for Psychosis in People With Alzheimer's Disease

https://www.alzheimers.gov/clinical-trials/karxt-psychosis-people-alzheimers-disease-0?utm_source=nia-eblast&utm_medium=email&utm_campaign=clinicaltrials-20231220 Start: December 2023 End: July 2025 Enrollment: 400

Interleukin-2 To Reduce Inflammation in Older Adults With Alzheimer's Disease

https://www.alzheimers.gov/clinical-trials/interleukin-2-reduce-inflammation-older-adults-alzheimers-disease?utm_source=nia-eblast&utm_medium=email&utm_campaign=clinicaltrials-20231220 Start: Mar. 17, 2022 End: Dec. 30, 2025 Enrollment: 40

[11C]-CS1P1 PET Imaging To Detect Brain Inflammation in People With Dementia

https://www.alzheimers.gov/clinical-trials/11c-cs1p1-pet-imaging-detect-brain-inflammation-people-dementia?utm_source=nia-eblast&utm_medium=email&utm_campaign=clinicaltrials-20231220 Start: May 5, 2023 End: May 2026 Enrollment: 80

Virtual Reality for Brain Health

https://www.alzheimers.gov/clinical-trials/virtual-reality-brain-health?utm_source=nia-eblast&utm_medium=email&utm_campaign=clinicaltrials-20231220 Start: Aug. 8, 2023 End: Feb. 1, 2029 Enrollment: 150v

Mindful Walking Program To Slow Cognitive Decline in Older African Americans

https://www.alzheimers.gov/clinical-trials/mindful-walking-program-slow-cognitive-decline-older-african-americans?utm_source=nia-eblast&utm_medium=email&utm_campaign=clinicaltrials-20231220 Start: May 16, 2023 End: Sept. 30, 2025 Enrollment: 114

Find Clinical Trials: Volunteers needed for studies to advance dementia research

https://www.alzheimers.gov/clinical-trials?utm_source=nia-eblast&utm_medium=email&utm_campaign=clinicaltrials-20231220

6 months of Kaftrio treatment found to reduce inflammation in CF

https://cysticfibrosisnewstoday.com/news/kaftrio-use-cf-6-months-reduces-inflammation-new-study-finds/?utm_source=CF&utm_campaign=ca8505055f-CF_ENL_3.0_US&utm_medium=email&utm_term=0_b075749015-ca8505055f-72020733

NIA’s evolving toolbox to study the science of stress

https://www.nia.nih.gov/research/blog/2023/12/nias-evolving-toolbox-study-science-stress?utm_source=NIA+Main&utm_campaign=b51fd47179-blog-stress-12-20&utm_medium=email&utm_term=0_-8180ce9847-%5BLIST_EMAIL_ID%5D

Seeking Success in Science Through NIH-Funded Training BY KIMBERLY ROUSSEAU

https://biobeat.nigms.nih.gov/2023/12/seeking-success-in-science-through-nih-funded-training/?utm_medium=email&utm_source=govdelivery

Claira Sohn Cultivates Neurons and Diversity in the STEM Community BY ABBEY BIGLER-COYNE

https://biobeat.nigms.nih.gov/2023/10/claira-sohn-cultivates-neurons-and-diversity-in-the-stem-community/?utm_medium=email&utm_source=govdelivery

Biomedical STI prevention evidence is inadequate for cisgender women NIH leadership calls for population-specific considerations in study design.

https://www.nih.gov/news-events/news-releases/biomedical-sti-prevention-evidence-inadequate-cisgender-women

miércoles, 20 de diciembre de 2023

Last Days of Life (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/advanced-cancer/caregivers/planning/last-days-hp-pdq?cid=eb_govdel#top

RUNX1-Familial Platelet Disorder (PDQ®)–Health Professional Version

https://www.cancer.gov/publications/pdq/information-summaries/genetics/runx1-hp-pdq?cid=eb_govdel#top

DDX41-Associated Myeloid Malignancies (PDQ®)–Health Professional Version

https://www.cancer.gov/publications/pdq/information-summaries/genetics/ddx41-hp-pdq?cid=eb_govdel#top

CEBPA-Associated Familial Acute Myeloid Leukemia (PDQ®)–Health Professional Version

https://www.cancer.gov/publications/pdq/information-summaries/genetics/cebpa-hp-pdq?cid=eb_govdel#top

Pediatric Gastric Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/stomach/hp/pediatric-gastric-treatment-pdq?cid=eb_govdel#top

Pediatric Chimeric Antigen Receptor (CAR) T-Cell Therapy (PDQ®)–Health Professional Version

https://www.cancer.gov/types/childhood-cancers/hp-stem-cell-transplant/car-t-cell-therapy?cid=eb_govdel#top

Pediatric Allogeneic Hematopoietic Stem Cell Transplant (PDQ®)–Health Professional Version

https://www.cancer.gov/types/childhood-cancers/hp-stem-cell-transplant/allogeneic?cid=eb_govdel#top

Osteosarcoma and Undifferentiated Pleomorphic Sarcoma of Bone Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/bone/hp/osteosarcoma-treatment-pdq?cid=eb_govdel#top

Complications, Graft-Versus-Host Disease, and Late Effects After Pediatric Hematopoietic Stem Cell Transplant (PDQ®)–Health Professional Version

https://www.cancer.gov/types/childhood-cancers/hp-stem-cell-transplant/gvhd?cid=eb_govdel#top

Childhood Thyroid Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/thyroid/hp/child-thyroid-treatment-pdq?cid=eb_govdel#top

Childhood Rhabdomyosarcoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/soft-tissue-sarcoma/hp/rhabdomyosarcoma-treatment-pdq?cid=eb_govdel#top

Childhood Pleuropulmonary Blastoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/lung/hp/child-pleuropulmonary-blastoma-treatment-pdq?cid=eb_govdel#top

Childhood Nasopharyngeal Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/head-and-neck/hp/child/nasopharyngeal-treatment-pdq?cid=eb_govdel#top

Childhood Melanoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/skin/hp/child-melanoma-treatment-pdq?cid=eb_govdel#top

Childhood Liver Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq?cid=eb_govdel#top

Childhood Laryngeal Tumors Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/head-and-neck/hp/child/laryngeal-treatment-pdq?cid=eb_govdel#top

Childhood Chordoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/bone/hp/child-chordoma-treatment-pdq?cid=eb_govdel#top

Childhood Basal Cell Carcinoma and Squamous Cell Carcinoma of the Skin Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/skin/hp/child-skin-treatment-pdq?cid=eb_govdel#top

Chronic sleep deficiency increases insulin resistance in women, especially postmenopausal women

https://www.nhlbi.nih.gov/news/2023/chronic-sleep-deficiency-increases-insulin-resistance-women-especially-postmenopausal

Making Strides to Address COPD in Rural Communities

https://www.nhlbi.nih.gov/news/2023/making-strides-address-copd-rural-communities

Stretchable electronics to map the inside of the heart? It’s not from a movie

https://www.nhlbi.nih.gov/news/2023/stretchable-electronics-map-inside-heart-its-not-movie

Eradicating Rheumatic Heart Disease

https://www.nhlbi.nih.gov/news/2023/eradicating-rheumatic-heart-disease

Mini hearts in a dish: A big win for cardiac research

https://www.nhlbi.nih.gov/news/2023/mini-hearts-dish-big-win-cardiac-research

NIST Calls for Information to Support Safe, Secure and Trustworthy Development and Use of Artificial Intelligence

https://www.nist.gov/news-events/news/2023/12/nist-calls-information-support-safe-secure-and-trustworthy-development-and

martes, 19 de diciembre de 2023

Know Your Treatment Options for COVID-19

https://www.fda.gov/consumers/consumer-updates/know-your-treatment-options-covid-19?utm_medium=email&utm_source=govdelivery

Skin Cancer Prevention (PDQ®)–Health Professional Version

https://www.cancer.gov/types/skin/hp/skin-prevention-pdq?cid=eb_govdel#top

Chronic Lymphocytic Leukemia Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/leukemia/hp/cll-treatment-pdq?cid=eb_govdel#top

Cancer of Unknown Primary (CUP) Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/unknown-primary/hp/unknown-primary-treatment-pdq?cid=eb_govdel#top

Base-Covered HIV-1 Envelope Ectodomains and Their Use

https://www.techtransfer.nih.gov/tech/tab-4474

Magnetic Seizure Therapy as Effective as Electroconvulsive Therapy for Treating Depression

https://www.nimh.nih.gov/news/science-news/2023/magnetic-seizure-therapy-as-effective-as-electroconvulsive-therapy-for-treating-depression

Presenters Have Hope for the Future of Trial Design in Pediatric Chronic Kidney Disease

https://www.ajmc.com/view/presenters-have-hope-for-the-future-of-trial-design-in-pediatric-chronic-kidney-disease

“Mask up!” Soon, AI may be prompting healthcare workers

https://innovationdistrict.childrensnational.org/soon-ai-may-be-prompting-healthcare-workers/

M.D. in your pocket: New platform allows rare disease patients to carry medical advice everywhere

https://innovationdistrict.childrensnational.org/md-in-your-pocket/

Modified aquapheresis for the smallest patients in intensive care

https://innovationdistrict.childrensnational.org/modified-aquapheresis-for-the-smallest-patients-in-intensive-care/

Ensuring age-friendly environments for all The Lancet Healthy Longevity

https://www.thelancet.com/journals/lanhl/issue/vol4no12/PIIS2666-7568(23)X0012-9

Moderate and vigorous leisure time physical activity in older adults and Alzheimer's disease-related mortality in the USA: a dose–response, population-based study

https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(23)00212-X/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhl&utm_campaign=update-lanhl&utm_medium=email&_hsmi=286849281&_hsenc=p2ANqtz--91hiNyIjCsO5UTEHP3r9zCDFLVOKagE06NIwmbi6RGVe944tV1EcpFRjdUvBcunbn3ImwwkQF4sLK7n-_jUYALAhCqw&utm_content=286679853&utm_source=hs_email

Personality traits are related to measures of neurodegeneration

https://www.nia.nih.gov/news/personality-traits-are-related-measures-neurodegeneration?utm_source=nia-eblast&utm_medium=email&utm_campaign=news-20231218

Could fasting reset the body’s clock and protect the brain against Alzheimer’s?

https://www.nia.nih.gov/news/could-fasting-reset-bodys-clock-and-protect-brain-against-alzheimers?utm_source=nia-eblast&utm_medium=email&utm_campaign=news-20231218

FDA updates prescribing information for all opioid pain medicines to provide additional guidance for safe use Includes updates to help reduce unnecessary prescribing

https://www.fda.gov/drugs/drug-safety-and-availability/fda-updates-prescribing-information-all-opioid-pain-medicines-provide-additional-guidance-safe-use?utm_medium=email&utm_source=govdelivery

NIH researchers create genetic atlas detailing early stages of zebrafish development Zebrafish are a powerful model for studying embryonic progression in vertebrates.

https://www.nih.gov/news-events/news-releases/nih-researchers-create-genetic-atlas-detailing-early-stages-zebrafish-development

FDA Approves FRUZAQLA (Fruquintinib) in Refractory Metastatic Colorectal Cancer

https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/217564s000lbl.pdf?utm_medium=email&utm_source=govdelivery

Newborn Screening for Severe Combined Immunodeficiency: Lessons Learned from Screening and Follow-Up of the Preterm Newborn Population

https://www.mdpi.com/2409-515X/9/4/68

W. Kimryn Rathmell begins work as 17th director of the National Cancer Institute

https://www.cancer.gov/news-events/press-releases/2023/rathmell-nci-director

What is the Arkansas Research Alliance?

https://aralliance.org/?utm_medium=email&utm_source=govdelivery

Beware of Illegally Marketed Diabetes Treatments, Fraudulent Pharmacies

https://www.fda.gov/consumers/consumer-updates/beware-illegally-marketed-diabetes-treatments-fraudulent-pharmacies?utm_medium=email&utm_source=govdelivery

lunes, 18 de diciembre de 2023

Metabolic syndrome linked to higher pancreatic cancer risk, study shows

https://www.news-medical.net/news/20231217/Metabolic-syndrome-linked-to-higher-pancreatic-cancer-risk-study-shows.aspx

Study supports limiting red meat intake for type 2 diabetes prevention, highlights alternative protein sources

https://www.news-medical.net/news/20231217/Study-supports-limiting-red-meat-intake-for-type-2-diabetes-prevention-highlights-alternative-protein-sources.aspx

Late-night eating linked to higher cardiovascular disease risk, study suggests

https://www.news-medical.net/news/20231217/Late-night-eating-linked-to-higher-cardiovascular-disease-risk-study-suggests.aspx

Air pollution linked to increased risk of stroke and dementia transition, study reveals

https://www.news-medical.net/news/20231217/Air-pollution-linked-to-increased-risk-of-stroke-and-dementia-transition-study-reveals.aspx

Study highlights link between sleep disturbances and behavioral issues in preschool children

https://www.news-medical.net/news/20231217/Study-highlights-link-between-sleep-disturbances-and-behavioral-issues-in-preschool-children.aspx

Trends in migraine incidence among women of childbearing age from 1990 to 2019 and the prediction for 2030: an analysis of national data in China

https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-023-01692-0 The Journal of Headache and Pain https://thejournalofheadacheandpain.biomedcentral.com/

Progesterone distribution in the trigeminal system and its role to modulate sensory neurotransmission: influence of sex

https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-023-01687-x The Journal of Headache and Pain https://thejournalofheadacheandpain.biomedcentral.com/

Orphanet Journal of Rare Diseases: Real life data: follow-up assessment on Spanish Gaucher disease patients treated with eliglustat. TRAZELGA project

https://ojrd.biomedcentral.com/

Mental Health Matters Podcast: The Evolution of Brain Stimulation Therapy

https://www.nimh.nih.gov/news/media/2023/the-evolution-of-brain-stimulation-therapy?utm_campaign=75&utm_medium=email&utm_source=govd

REVOLUTIONARY EYELID PACEMAKER ENABLES BLINKING Hundreds of thousands of people suffer from facial paralysis each year, and until now there was no solution for the inability to blink.

REVOLUTIONARY EYELID PACEMAKER ENABLES BLINKING Hundreds of thousands of people suffer from facial paralysis each year, and until now there was no solution for the inability to blink. https://www.israel21c.org/revolutionary-eyelid-pacemaker-enables-blinking/

Podcast: Rare on Air

https://www.eurordis.org/rare-on-air/

A comprehensive approach to mental health

https://health.ec.europa.eu/publications/comprehensive-approach-mental-health_en

EURORDIS welcomes European Parliament vote on European Health Data Space

https://www.eurordis.org/response-ehds-parliament-vote/

The European Conference on Rare Diseases and Orphan Products (ECRD)

https://www.rare-diseases.eu/

Nanoplastics may help set the stage for Parkinson’s risk

https://www.nih.gov/news-events/nih-research-matters/nanoplastics-may-help-set-stage-parkinson-s-risk

Impact of COVID-19 infections and vaccines on preterm birth

https://www.nih.gov/news-events/nih-research-matters/impact-covid-19-infections-vaccines-preterm-birth

Deaths associated with pollution from coal power plants

https://www.nih.gov/news-events/nih-research-matters/deaths-associated-pollution-coal-power-plants

NIH study shows how genes in retina get regulated during development Genome topology map of human retina development lays foundation for understanding diverse clinical phenotypes in simple and complex eye diseases.

https://www.nih.gov/news-events/news-releases/nih-study-shows-how-genes-retina-get-regulated-during-development

Replication-Competent Virus Detected in Blood of a Fatal COVID-19 Case

https://www.acpjournals.org/doi/10.7326/L23-0253?utm_campaign=+58704312&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

Advanced imaging reveals altered brain chemistry of babies with congenital heart disease

https://medicalxpress.com/news/2023-10-advanced-imaging-reveals-brain-chemistry.html

Declaring a child brain dead can prompt showdowns. New rules seek to resolve those doubts.

https://www.usatoday.com/story/news/health/2023/10/12/brain-dead-diagnoses-can-be-controversial-new-guidance-looks-to-help/71130606007/

2023 Head and Heart Honoree – Dr. Roger Packer

Novel camera + machine learning = hope for more precise neurosurgery

https://innovationdistrict.childrensnational.org/novel-camera-machine-learning-hope-for-more-precise-neurosurgery/

A new way to treat pediatric gliomas with BRAF V600 mutations

https://innovationdistrict.childrensnational.org/a-new-way-to-treat-pediatric-gliomas-with-braf-v600-mutations/

20 years of leadership in the concussion space

https://innovationdistrict.childrensnational.org/20-years-of-leadership-in-the-concussion-space/

domingo, 17 de diciembre de 2023

The infant gut virome is associated with preschool asthma risk independently of bacteria

https://www.nature.com/articles/s41591-023-02685-x

Beyond the exome: utility of long-read whole genome sequencing in exome-negative autosomal recessive diseases

https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-023-01270-8

Attitudes toward pre-symptomatic screening for Alzheimer’s dementia in five European countries: a comparison of family members of people with Alzheimer’s dementia versus non-family members

https://www.frontiersin.org/articles/10.3389/fgene.2023.1305107/full

Post-viral sequelae of COVID-19 and influenza Monica Gandhi

https://www.thelancet.com/journals/laninf/onlinefirst

Identifying actionable druggable targets for breast cancer: Mendelian randomization and population-based analyses

https://www.thelancet.com/journals/ebiom/issue/vol98nonull/PIIS2352-3964(23)X0011-5

Securing the future of Europe's ageing population by 2050 The Lancet Regional Health – Europe

https://www.thelancet.com/journals/lanepe/issue/vol35nonull/PIIS2666-7762(23)X0010-6

Oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in China: a multicentre, double-blind, phase 3, randomised controlled study

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00577-7/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=lancetcovid22&utm_medium=email&_hsmi=286691763&_hsenc=p2ANqtz-88WGnDTCW9IppfVzCbg7tsE5k9RZ4E11mG4Y1XGnz0RGw-eww9pkFnq3J7sVVMDa_gXWtSB1XoVOlL3O9w6Y6JLqtERw&utm_content=286678291&utm_source=hs_email

3-year outcomes of discharged survivors of COVID-19 following the SARS-CoV-2 omicron (B.1.1.529) wave in 2022 in China: a longitudinal cohort study

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00387-9/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=lancetcovid22&utm_medium=email&_hsmi=286691763&_hsenc=p2ANqtz-_XKAYxADSVCsxNfsSMlDp-4jWbubA21Mw6e_-8u1y9Zj-ASeUu7TAhjuWyCn94aVUfWdx51mH-mqPDjMuSSSeMcbjSDA&utm_content=286678291&utm_source=hs_email

ACE2-independent SARS-CoV-2 virus entry through cell surface GRP78 on monocytes – evidence from a translational clinical and experimental approach

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00435-8/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=lancetcovid22&utm_medium=email&_hsmi=286691763&_hsenc=p2ANqtz-_Yk0dIkNaKDpUbOCBpajZrWjLEaZTn5-lM2Z-sJ8FYneoKJN8sC4g54r_OELuF6Eghymr7lpupbj7TOZrXeDBac5aOvg&utm_content=286678291&utm_source=hs_email

Impact of the COVID-19 pandemic on implementation of novel guideline-directed medical therapies for heart failure in Germany: a nationwide retrospective analysis

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00197-7/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=lancetcovid22&utm_medium=email&_hsmi=286691763&_hsenc=p2ANqtz-8-ZbI_R7rba99DF-xx8b-wm5A1ra0J7GUXGkbYF5qkAoWsZFza8WWa5V1INmBZTM82vqsMQf1GVS0_dSz9xBarhqjXwg&utm_content=286678291&utm_source=hs_email

sábado, 16 de diciembre de 2023

Therapeutic advances and open questions in postpartum-depression research eBioMedicine

https://www.thelancet.com/journals/ebiom/issue/vol98nonull/PIIS2352-3964(23)X0011-5

Cellular mechanisms associated with sub-optimal immune responses to SARS-CoV-2 bivalent booster vaccination in patients with Multiple Myeloma

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00452-8/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=lancetcovid22&utm_medium=email&_hsmi=286691763&_hsenc=p2ANqtz-88DxxOb6QNO_AZ2EctyV66C4_8ax4b7BPI4fL2riPDhfCnjf_UKmxGd4sWyUyleHc1iF5yO2JZ_1xZT8GiYe8T0AMk_A&utm_content=286678291&utm_source=hs_email

Efficacy and safety of MP1032 plus standard-of-care compared to standard-of-care in hospitalised patients with COVID-19: a multicentre, randomised double-blind, placebo-controlled phase 2a trial

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00229-6/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=lancetcovid22&utm_medium=email&_hsmi=286691763&_hsenc=p2ANqtz-_Pd6xzkeEOiJCMl0bJfHhwJLna2cj31On0NHxLZtT00AZXp9UF9L3xvbA3JeZRwulHbp6UWQaZED3p5J4TTK55pD4rOg&utm_content=286678291&utm_source=hs_email

A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00685-0/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=lancetcovid22&utm_medium=email&_hsmi=286691763&_hsenc=p2ANqtz--CJg7hxIOHYnLMeNREGL_jzSW1-0cdJ6a6Yi0t7FCRgs_Zfj65SVUWzUtMMLNfEcmqz1MoGwuJE5iDVcOLbkonA36pKQ&utm_content=286678291&utm_source=hs_email

Story of discovery: NEI-funded research paves way for new dry AMD drugs FDA approves first drugs to treat the dry form of age-related macular degenerationStory of discovery: NEI-funded research paves way for new dry AMD drugs FDA approves first drugs to treat the dry form of age-related macular degeneration

https://www.nei.nih.gov/about/news-and-events/news/story-discovery-nei-funded-research-paves-way-new-dry-amd-drugs

DAMN DINKS! PLAYING PICKLEBALL PAIN-FREE

Damn Dinks! Playing Pickleball Pain-Free By Ivanhoe Broadcast News on December 24, 2023 https://www.ivanhoe.com/?p=32007&preview=1&_ppp=9edda0a776

AI FRAUD ALERT: DON’T FALL FOR DEEPFAKES

AI Fraud Alert: Don’t Fall for Deepfakes By Ivanhoe Broadcast News on December 23, 2023 https://www.ivanhoe.com/?p=32004&preview=1&_ppp=816b930419

PASS ON THE JOY: GIFTS THAT GIVE

Pass on The Joy: Gifts that Give By Ivanhoe Broadcast News on December 23, 2023 https://www.ivanhoe.com/?p=32001&preview=1&_ppp=468ca79e08

BEATING LATE-STAGE CANCERS: TURNING CANCER CELLS AGAINST THEMSELVES

Beating Late-Stage Cancers By Ivanhoe Broadcast News on December 22, 2023 https://www.ivanhoe.com/?p=32022&preview=1&_ppp=35a8df79fa

KETAMINE WORKS ON TREATMENT-RESISTANT DEPRESSION

Ketamine Works on Treatment-Resistant Depression By Ivanhoe Broadcast News on December 21, 2023 https://www.ivanhoe.com/?p=32019&preview=1&_ppp=d02dc1703f

FIBROID FREEDOM: A HYSTERECTOMY-FREE SOLUTION

Fibroids Freedom: A Hysterectomy-Free Solution By Ivanhoe Broadcast News on December 20, 2023 https://www.ivanhoe.com/?p=32016&preview=1&_ppp=b7c12a0064

PILL-LESS PAIN RELIEF: NEUROSTIMULATORS REPLACING OPIOIDS

Pill-less Pain Relief: Neurostimulators Replacing Opioids By Ivanhoe Broadcast News on December 19, 2023 https://www.ivanhoe.com/?p=32013&preview=1&_ppp=de5e77e390

ROLLING AWAY BLOOD CLOTS

Rolling Away Blood Clots By Ivanhoe Broadcast News on December 18, 2023 https://www.ivanhoe.com/?p=32010&preview=1&_ppp=5f8251fa5a

FDA approves enfortumab vedotin-ejfv with pembrolizumab for locally advanced or metastatic urothelial cancer

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-enfortumab-vedotin-ejfv-pembrolizumab-locally-advanced-or-metastatic-urothelial-cancer

The Lancet Regional Health in conversation with Sibylle Pramhas and Kristian Petersen on cannabidiol for painful knee osteoarthritis

https://thelancetregionalhealth.buzzsprout.com/2223483/14092873-sibylle-pramhas-and-kristian-petersen-on-cannabidiol-for-painful-knee-osteoarthritis?utm_campaign=update-lanepe&utm_medium=email&_hsmi=286542186&_hsenc=p2ANqtz-_p1ous0f4y5TX20JA36npgXs-uIxv41AwzW6UsMeOlUZcXBY-0y87aHBwiTShfyyKauE8sD6vNTCj_eDjyFQAN_UhsXw&utm_content=286540158&utm_source=hs_email

African American patients face lifetime of challenges living with CF Interviews detail cultural insensitivity from healthcare teams, other concerns

https://cysticfibrosisnewstoday.com/news/care-disparities-face-african-american-cystic-fibrosis-patients/?utm_source=CF&utm_campaign=9f228b84a4-CF_ENL_3.0_US&utm_medium=email&utm_term=0_b075749015-9f228b84a4-72020733

Urinary Fas a potential biomarker for antibiotic-linked kidney injury Researchers analyzed urine samples before and after antibiotic treatment

https://cysticfibrosisnewstoday.com/news/urinary-fas-potential-biomarker-antibiotic-linked-kidney-injury/?utm_source=CF&utm_campaign=9f228b84a4-CF_ENL_3.0_US&utm_medium=email&utm_term=0_b075749015-9f228b84a4-72020733

Medical trauma bubbles to the surface again after a hospitalization With medical PTSD, it's challenging to return to a hospital setting

https://cysticfibrosisnewstoday.com/columns/medical-trauma-bubbles-surface-after-hospitalization/?utm_source=CF&utm_campaign=9f228b84a4-CF_ENL_3.0_US&utm_medium=email&utm_term=0_b075749015-9f228b84a4-72020733

Experiencing the Neural Symphony Underlying Memory through a Blend of Science and Art Posted on December 8th, 2023 by John Ngai, PhD, NIH BRAIN Initiative

https://directorsblog.nih.gov/2023/12/08/experiencing-the-neural-symphony-underlying-memory-through-a-blend-of-science-and-art/

Effect of baseline oestradiol serum concentration on the efficacy of anastrozole for preventing breast cancer in postmenopausal women at high risk: a case-control study of the IBIS-II prevention trial

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00578-8/fulltext?dgcid=hubspot_email_conferencealerts_sabcs23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=285418105&_hsenc=p2ANqtz--2_1eQTo8qWjNOcBDcs5RQ2RTK1iushUPsbpgwnuWGbeN7MFUzEtdk7Z-Tj2GyP1TNwP2RE7_dJGZx5O0WDuSYSS1gwQ&utm_content=285418105&utm_source=hs_email

viernes, 15 de diciembre de 2023

Airborne Viruses | Physical Activity | Lowering Blood Pressure | High-Risk Pregnancies | Teen Essay Contest

https://content.govdelivery.com/accounts/USNIH/bulletins/37fcbdc?reqfrom=share

FDA approves belzutifan for advanced renal cell carcinoma

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-belzutifan-advanced-renal-cell-carcinoma?utm_medium=email&utm_source=govdelivery

FDA Strengthens Breast Implant Safety Requirements

https://www.fda.gov/medical-devices/implants-and-prosthetics/breast-implants?utm_medium=email&utm_source=govdelivery

NIH Research Identifies Opportunities to Improve Future HIV Vaccine Candidates Study Suggests Greater CD8+ T-Cell Activity May Increase HIV Immunity

https://www.niaid.nih.gov/news-events/nih-research-identifies-opportunities-improve-future-hiv-vaccine-candidates?utm_campaign=+58722150&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

Virtual Mind–Body Fitness Classes Show Unexpected Benefit in People with Cancer

https://www.cancer.gov/news-events/cancer-currents-blog/2023/mind-body-fitness-cancer-side-effects?cid=eb_govdel

jueves, 14 de diciembre de 2023

Human Gene Therapy

https://www.liebertpub.com/toc/hum/0/0?utm_campaign=HUM+FP+December+13%2C+2023&utm_content=CTA-Button&utm_term=&utm_medium=email&utm_source=Adestra

Summary of Advances In Autism Research 2022

https://iacc.hhs.gov/publications/summary-of-advances/2022/

Taking on the stigma of ADHD

https://magazine.medlineplus.gov/article/taking-on-the-stigma-of-adhd?utm_medium=email&utm_source=govdelivery

Antibody Drug Ejects Problematic Proteins from Cancer Cells

https://www.cancer.gov/news-events/cancer-currents-blog/2023/iga-antibody-inside-cancer-cells?cid=eb_govdel

NIH research identifies opportunities to improve future HIV vaccine candidates Study suggests greater CD8+ T-cell activity may increase HIV immunity

https://www.nih.gov/news-events/news-releases/nih-research-identifies-opportunities-improve-future-hiv-vaccine-candidates

Reported drug use among adolescents continued to hold below pre-pandemic levels in 2023 New data show relatively low use of illicit substances, yet overdose death rates among teens have risen in recent years.

https://www.nih.gov/news-events/news-releases/reported-drug-use-among-adolescents-continued-hold-below-pre-pandemic-levels-2023

Brain Initiative Cell Census Network 2.0

https://www.nature.com/collections/fgihbeccbd

The Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative

https://braininitiative.nih.gov/

Scientists Unveil Complete Cell Map of a Whole Mammalian Brain NIH-funded atlas characterizes over 32 million cells across the mouse brain

https://www.nimh.nih.gov/news/science-news/2023/scientists-unveil-complete-cell-map-of-a-whole-mammalian-brain

Berberine and Weight Loss: What You Need To Know

https://www.nccih.nih.gov/health/berberine-and-weight-loss-what-you-need-to-know?nav=govd Berberine is a substance found in a variety of plants, including goldenseal, barberry, Oregon grape, and others. Plants containing berberine have a long history of use in both Ayurvedic and Chinese medicine. In modern times, plants containing berberine have been used for infections, skin diseases, digestive disorders, and other conditions. Berberine is currently being studied for its effects on diabetes and risk factors for heart disease. Recently, it has become popular as a potential weight loss aid.

Children taking CFTR modulators may grow taller by age 18 Use of therapy may help bridge gap in adult height, study suggests

https://cysticfibrosisnewstoday.com/news/cf-children-taking-cftr-modulators-may-be-taller-adults-study/?utm_source=CF&utm_campaign=40818cc848-CF_ENL_3.0_US&utm_medium=email&utm_term=0_b075749015-40818cc848-72020733

Drop in blood sugar levels seen within months of starting Kaftrio But for CF patients with diabetes, need for insulin goes unchanged

https://cysticfibrosisnewstoday.com/news/blood-sugar-levels-drop-with-kaftrio-cf-diabetes-constant/?utm_source=CF&utm_campaign=40818cc848-CF_ENL_3.0_US&utm_medium=email&utm_term=0_b075749015-40818cc848-72020733

Fighting for global access to equitable CF healthcare, treatment Potentially lifesaving therapies should be available to patients in all countries

https://cysticfibrosisnewstoday.com/columns/fighting-global-access-equitable-cf-healthcare-treatment/?utm_source=CF&utm_campaign=40818cc848-CF_ENL_3.0_US&utm_medium=email&utm_term=0_b075749015-40818cc848-72020733

Cough, sputum symptoms tied to impaired quality of life: Pilot study Researchers applied CASA-Q to 48 adults with CF

https://cysticfibrosisnewstoday.com/news/cough-sputum-symptoms-cf-tied-impaired-quality-life/?utm_source=CF&utm_campaign=40818cc848-CF_ENL_3.0_US&utm_medium=email&utm_term=0_b075749015-40818cc848-72020733

Will variants of uncertain significance still exist in 2030?

https://pubmed.ncbi.nlm.nih.gov/38086381/ From the abstract: "In 2020, the National Human Genome Research Institute (NHGRI) made ten “bold predictions,” including that “the clinical relevance of all encountered genomic variants will be readily predictable, rendering the diagnostic designation ‘variant of uncertain significance (VUS)’ obsolete.” We discuss the prospects for this prediction, arguing that many, if not most, VUS in coding regions will be resolved by 2030. We outline a confluence of recent changes making this possible. "

Comprehensive assessment of the genetic characteristics of small for gestational age newborns in NICU: from diagnosis of genetic disorders to prediction of prognosis

https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-023-01268-2 From the abstract: "Among the 723 SGA newborns, 88(12.2%) received genetic diagnosis, including 42(47.7%) with monogenic diseases and 46(52.3%) with chromosomal abnormalities. SGA with genetic diagnosis showed higher rates in severe SGA(54.5% vs. 41.9%, P=0.0025) than SGA without genetic diagnosis. SGA with chromosomal abnormalities showed higher incidences of physical and neurodevelopmental delay compared to those with monogenic diseases (45.7% vs. 19.0%, P=0.012). "

'It's all gone': CAR-T therapy forces autoimmune diseases into remission

https://pubmed.ncbi.nlm.nih.gov/38087105/ From the article: "Engineered immune cells have given 15 people with once-debilitating autoimmune disorders a new lease on life, free from fresh symptoms or treatments. The results raise hopes that the approach — called CAR-T-cell therapy — might one day be extended to a variety of other conditions fuelled by rogue immune cells that produce antibodies against the body’s own tissues. "

Utility of smart watches for identifying arrhythmias in children

https://www.nature.com/articles/s43856-023-00392-9 From the abstract: " Arrhythmia symptoms are frequent complaints in children and often require a pediatric cardiology evaluation. Data regarding the clinical utility of wearable technologies are limited in children. We hypothesize that a smart watch can capture arrhythmias in children. We present an analysis of patients =18 years-of-age who had signs of an arrhythmia documented by a smart watch. We include patients evaluated at our center over a 4-year-period and highlight those receiving a formal arrhythmia diagnosis. We evaluate the role of the smart watch in arrhythmia diagnosis, the results of other ambulatory cardiac monitoring studies, and findings of any EP studies."