martes, 31 de octubre de 2023

Extreme heat projected to increase cardiovascular deaths

https://www.nih.gov/news-events/news-releases/extreme-heat-projected-increase-cardiovascular-deaths

FDA approves toripalimab-tpzi for nasopharyngeal carcinoma

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-toripalimab-tpzi-nasopharyngeal-carcinoma

Combining chemotherapy, trastuzumab, and immune-checkpoint inhibitors in HER2-positive gastro-oesophageal cancer

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02296-1/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278989396&_hsenc=p2ANqtz-8bPJVar4gDxDVB8xVvEClFy1XuPwwbzZAAMrq1ejmKPgPB4gDCvfQb-eyHymUeiwwvLsQqgZ3V6xf5YW4hdJCNT-jXQQ&utm_content=278989396&utm_source=hs_email

Pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma: interim analyses from the phase 3 KEYNOTE-811 randomised placebo-controlled trial

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02033-0/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278989396&_hsenc=p2ANqtz-_DXlyY637YoMBrDB6tCJetmNCw6-jINngS79cQ7v5D6-OH4QlrfTjYir5_xNFjGGmxqaMjqCZog8jKj_b5hcwianVQqQ&utm_content=278989396&utm_source=hs_email

Pembrolizumab as a first-line treatment for advanced gastric cancer

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00526-0/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278989396&_hsenc=p2ANqtz--y-lgGP-7TkTSrXc-68G5e8cUOCHqIHi0jECtglaMV-k8nQaxTxg_0DM1s00UIVPnSbKDNY28xlDJIRSVDyxScqP0oRg&utm_content=278989396&utm_source=hs_email

Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for HER2-negative advanced gastric cancer (KEYNOTE-859): a multicentre, randomised, double-blind, phase 3 trial

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00515-6/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278989396&_hsenc=p2ANqtz-86XhOP4dNMwfph1KDsAdxodmss8ei3fOSpDksvVexTBBfroshpB39GaACGRhyJ4WcPL2AUXrTA6Pq-j6y3QwsjjBkWbw&utm_content=278989396&utm_source=hs_email

Neoadjuvant cemiplimab and surgery for stage II–IV cutaneous squamous-cell carcinoma: follow-up and survival outcomes of a single-arm, multicentre, phase 2 study

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00459-X/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278989396&_hsenc=p2ANqtz-90ab4dzjhBbFw3befvapEgnn5wLeMk39LUDgFYuqv5xHdGMYSFQrTcxPK3-GIMFC8C8YTqWJWG9fC53P4DDHMtZbDOBw&utm_content=278989396&utm_source=hs_email

lunes, 30 de octubre de 2023

Protein found in spinal fluid may help predict mild cognitive impairment before symptoms appear

https://www.nia.nih.gov/news/protein-found-spinal-fluid-may-help-predict-mild-cognitive-impairment-before-symptoms-appear?utm_source=nia-eblast&utm_medium=email&utm_campaign=news-20231030

Taking a deep dive into the Alzheimer’s brain in search of understanding and new targets

https://www.nia.nih.gov/news/taking-deep-dive-alzheimers-brain-search-understanding-and-new-targets?utm_source=nia-eblast&utm_medium=email&utm_campaign=news-20231030

Studying the genomes of Ashkenazi Jewish people and other closely related groups may bolster Alzheimer’s research

https://www.nia.nih.gov/news/studying-genomes-ashkenazi-jewish-people-and-other-closely-related-groups-may-bolster?utm_source=nia-eblast&utm_medium=email&utm_campaign=news-20231030

Scientists find common brain network for substance use disorders

https://www.nia.nih.gov/news/scientists-find-common-brain-network-substance-use-disorders?utm_source=nia-eblast&utm_medium=email&utm_campaign=news-20231030

Social factors may predict mortality risk for older adults

https://www.nia.nih.gov/news/social-factors-may-predict-mortality-risk-older-adults?utm_source=nia-eblast&utm_medium=email&utm_campaign=news-20231030

Calorie restriction in humans builds strong muscle and stimulates healthy aging genes

https://www.nia.nih.gov/news/calorie-restriction-humans-builds-strong-muscle-and-stimulates-healthy-aging-genes?utm_source=nia-eblast&utm_medium=email&utm_campaign=news-20231030

domingo, 29 de octubre de 2023

Portfolio Diet Tied to Lower Risk for CVD, Stroke Pauline Anderson

https://www.medscape.com/viewarticle/997825

FDA Okays Drug for Duchenne Muscular Dystrophy Megan Brooks

https://www.medscape.com/viewarticle/997821

Low-Risk TAVR Studies: Divergent Long-Term Results Sue Hughes

https://www.medscape.com/viewarticle/997784?src=

Oct 27, 2023 This Week in Cardiology Podcast John M. Mandrola, MD

https://www.medscape.com/viewarticle/997776?src=

GI Symptoms During Menopause Deserve Attention David A. Johnson, MD

https://www.medscape.com/viewarticle/997022?src=

The Sobering Facts About Alcohol and Cancer Megan Brooks

https://www.medscape.com/viewarticle/997665?ecd=mkm_ret_231029_mscpmrk_onc_top-content_etid6002329&uac=148436CN&impID=6002329

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer - Tepkinly® (epcoritamab)

https://www.news-medical.net/news/20231028/MHRA-grants-conditional-marketing-authorization-for-AbbVies-Tepkinly-to-treat-aggressive-blood-cancer.aspx

Listening to favorite music has a larger effect on acute thermal pain reduction

https://www.news-medical.net/news/20231028/Listening-to-favorite-music-has-a-larger-effect-on-acute-thermal-pain-reduction.aspx

Antiviral efficacy of molnupiravir versus ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19 (PLATCOV): an open-label, phase 2, randomised, controlled, adaptive trial

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00493-0/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz-9NhpB_LoLx4P73O5bJOY8Oda39LJujMzXHsLlJpdWPPRSNHqdAQSHM7eNA78f3Dwp3mCo3889YYGiIK5IUeiimyOXl0w&utm_content=280145645&utm_source=hs_email

Immunogenicity and safety of AZD2816, a beta (B.1.351) variant COVID-19 vaccine, and AZD1222 (ChAdOx1 nCoV-19) as third-dose boosters for previously vaccinated adults: a multicentre, randomised, partly double-blinded, phase 2/3 non-inferiority immunobridging study in the UK and Poland

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00177-5/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz-9OZ4dLs-rJNwq-8YfU3xkJU2CfZSdEFhsoW2Tm9vc_ew_HSpsj6vosd2FiU9S7kHiVw2kECGZWbbMftN4-03VANcbaGw&utm_content=280145645&utm_source=hs_email

Physical fitness among children with diverse weight status during and after the COVID-19 pandemic: a population-wide, cohort study based on the Slovenian physical fitness surveillance system (SLOfit)

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00167-9/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz--6JGRW0E0QLvcNu-bgkNtXssC9bhHO2I2AKiYX1AhroJCnBAD7ocWdCf_rnp9NJqa3CJuq7EYQGEXXYsO8O69JPKrCIA&utm_content=280145645&utm_source=hs_email

Heterogeneous PD-L1 expression in metastases impacts immunotherapy response Xiaoqian Hu,Xinpei Deng,Jindong Xie,Hailin Tang,Yutian Zou

https://www.thelancet.com/journals/ebiom/issue/vol97nonull/PIIS2352-3964(23)X0010-3

Chronic alcohol consumption dysregulates innate immune response to SARS-CoV-2 in the lung

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00378-X/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz-_LhTsv1-Ntik0_T0X3CDky3MIbaTbrsQaPLeZHuZr0MuTG6xGG35Q3Ez5BSQydnP13jEMmhs5jidR2YFF80Xl-5UKu1Q&utm_content=280145645&utm_source=hs_email

Efficacy and safety of zapnometinib in hospitalised adult patients with COVID-19 (RESPIRE): a randomised, double-blind, placebo-controlled, multicentre, proof-of-concept, phase 2 trial

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00414-5/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz-8xiH4KaLWRAbZfBD8wZjFCupFtN2r6XrWzbMjN1sp6f9hW2fgWo-LNHPem1pJYRqif3NHecWm5zApVnuW553qgcu4TPA&utm_content=280145645&utm_source=hs_email

Neutralising antibody responses against SARS-CoV-2 Omicron BA.4/5 and wild-type virus in patients with inflammatory bowel disease following three doses of COVID-19 vaccine (VIP): a prospective, multicentre, cohort study

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00426-1/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz-9-hRHhBdYXhKNUyxOf5o6h38-bj6Fd-YpxmaSksfY78PCFypG8ARsi9YNq4DAWdtS-V4rasynUURJUcSZgR86Sb8dDQA&utm_content=280145645&utm_source=hs_email

Long-term symptom profiles after COVID-19 vs other acute respiratory infections: an analysis of data from the COVIDENCE UK study

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00428-5/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz-98nbuJtUj_dfWSTkeFqRgikH6RXPLs_xSq93Zw2xVupsKbPrNgaMUpoNxUcdHyViXXYKY2uA9BA1Ek_NQt0a8TNaZ00g&utm_content=280145645&utm_source=hs_email

Comparative effectiveness of nirmatrelvir/ritonavir versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised high-risk patients during Omicron waves: observational cohort study using the OpenSAFELY platform

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00160-6/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz--BUSrfI-dRCuFm7vdRx51cxloJv-mR-wEwGsssEq5ipgRPq4UYET4Rpmeu3xNYSSjAdq6MEYB6yNdkWX8W5mDDl_GT_Q&utm_content=280145645&utm_source=hs_email

Updating estimated trends in dementia incidence: evidence of increases in England Emma Nichols,Jinkook Lee

https://www.thelancet.com/journals/lanpub/issue/vol8no11/PIIS2468-2667(23)X0011-5

Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00166-7/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz-86Ur-pgRkDiFzX0wFlz9x_oBcL6pVi2AxCEkjxiO7Irm1d1FLqwmVYr2IaeZDR45i6oPnNPyTbn-nfSejnTWes9j7LDw&utm_content=280145645&utm_source=hs_email

The Lancet Respiratory Medicine in conversation with Betty Raman on multiorgan MRI abnormalities after hospitalisation with COVID-19

https://thelancetrespiratory.buzzsprout.com/1459960/13714119-betty-raman-on-multiorgan-mri-abnormalities-after-hospitalisation-with-covid-19?utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz--HlZxoHozRb02YJIsSh1vFh9lI0KCh8umhjOj2JTEdI-hdT3YXQhVlyM192rHQNdR-HRR1P_2wKRf9IiJO2Cc2o0TKBw&utm_content=280145645&utm_source=hs_email

Accuracy of package inserts of SARS-CoV-2 rapid antigen tests: a secondary analysis of manufacturer versus systematic review data

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00222-7/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz-8pdcS6A3NEkcDPFCFdToNK8hrR-7XCnCHPVWKnjzgfy1IJXJJ8JKxEoizAEi6i3R6SHSCn6rPQ9dxM7tUP4O54YM8QBw&utm_content=280145645&utm_source=hs_email

Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

https://www.thelancet.com/journals/landia/article/PIIS2213-8587(23)00253-X/fulltext?dgcid=hubspot_email_covidalerts&utm_campaign=covidalerts&utm_medium=email&_hsmi=280173067&_hsenc=p2ANqtz-9fUXHquDtx7GpUuNSGiUojvnD5L53B5Dpmf_Pbsn0iFu23oBAbQBTHr5OcNgCNITxiInDCtPGWiGz9JcUBtBCva7aGHQ&utm_content=280145645&utm_source=hs_email

sábado, 28 de octubre de 2023

What is the Anticholinergic Cognitive Burden Scale?

https://www.news-medical.net/health/What-is-the-Anticholinergic-Cognitive-Burden-Scale.aspx

Moderate wine consumption may reduce the risk of some cancers

https://www.news-medical.net/news/20231026/Moderate-wine-consumption-may-reduce-the-risk-of-some-cancers.aspx

Novel replacement strategy holds promise for the treatment of various genetic disorders

https://www.news-medical.net/news/20231027/Novel-replacement-strategy-holds-promise-for-the-treatment-of-various-genetic-disorders.aspx

Experts warn of 'silent epidemic' of high cholesterol in the UK

https://www.news-medical.net/news/20231028/Experts-warn-of-silent-epidemic-of-high-cholesterol-in-the-UK.aspx

New insights into how menopause affects women’s lives, health, workplaces

https://www.news-medical.net/news/20231028/New-insights-into-how-menopause-affects-womene28099s-lives-health-workplaces.aspx

Listening to favorite music has a larger effect on acute thermal pain reduction

https://www.news-medical.net/news/20231028/Listening-to-favorite-music-has-a-larger-effect-on-acute-thermal-pain-reduction.aspx

Non-alcoholic beers may be a happy hour for bacteria, study warns

https://www.news-medical.net/news/20231026/Non-alcoholic-beers-may-be-a-happy-hour-for-bacteria-study-warns.aspx

BLOOD CANCER: THE SILENT DISEASE

Blood Cancer: The Silent Disease By Ivanhoe Broadcast News on October 27, 2023 https://www.ivanhoe.com/medical-breakthroughs/blood-cancer-the-silent-disease/

WEIGHT LOSS: MANAGING BEHAVIOR IS CRUCIAL!

AUTISM AND SLEEP: PUTTING ISSUES TO BED

Autism and Sleep: Putting Issues to Bed By Ivanhoe Broadcast News on November 4, 2023 https://www.ivanhoe.com/?p=31670&preview=1&_ppp=13c92ae61a

KIDNEY DAMAGE AND NSAIDS

DIABETES DRUG TO SLOW AGING?

Diabetes Drug to Slow Aging? By Ivanhoe Broadcast News on November 5, 2023 https://www.ivanhoe.com/?p=31673&preview=1&_ppp=0561107d43

EYES, EARS, AND DEMENTIA RISK

LONG LASTING EFFECTS OF COVID-19: WHO, WHY & HOW?

COVID-19 Long Lasting Effects: Who, Why & How? By Ivanhoe Broadcast News on November 4, 2023 https://www.ivanhoe.com/?p=31667&preview=1&_ppp=4e203e1aa4

JUST BIRTH NETWORK: BREAKING RACIAL BARRIERS

Just Birth Network: Breaking Racial Barriers By Ivanhoe Broadcast News on November 3, 2023 https://www.ivanhoe.com/?p=31664&preview=1&_ppp=397ea1d8f2

PREGNANT AND BATTLING A BRAIN TUMOR

Pregnant and Battling a Brain Tumor By Ivanhoe Broadcast News on November 2, 2023 https://www.ivanhoe.com/?p=31662&preview=1&_ppp=62f3d82468

TODDLER’S TRIUMPH: TRANSFORMING LUCAS’ SKULL

Toddler’s Triumph over Birth Defect: Transforming Lucas’ Skull By Ivanhoe Broadcast News on November 1, 2023 https://www.ivanhoe.com/?p=31659&preview=1&_ppp=ba8571b733

ARTHROFIT: THE NEW FOUNTAIN OF YOUTH?

ArthroFit: The New Fountain of Youth? By Ivanhoe Broadcast News on October 31, 2023 https://www.ivanhoe.com/?p=31656&preview=1&_ppp=7bc232f32e

FLU, TAMIFLU & BEHAVIORAL CHANGES IN KIDS?

Flu, TamiFlu & Neuropsychiatric Events in Kids? By Ivanhoe Broadcast News on October 30, 2023 https://www.ivanhoe.com/?p=31649&preview=1&_ppp=c4943b5a0d

viernes, 27 de octubre de 2023

Sexually Transmitted Infections

https://www.thelancet.com/series/europe-sexually-transmitted-infections?dgcid=hubspot_email_conferencealerts_lanepesti23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278650000&_hsenc=p2ANqtz-_H_vO9kfX7krweInkODaBLgHhq06YUMXJ7-Ret2-jUtAdClH4Azoy_Q95yOPQ1I9OdHixqjO5HK_N03gkPNrw_myEiDQ&utm_content=278650000&utm_source=hs_email

Historical Trauma: Providing Trauma Informed Care to Patients with Sickle Cell Disease Thu, Nov 2, 2023 3:30 PM - 5:00 PM -03

https://register.gotowebinar.com/register/4579129913440197212?utm_medium=email&utm_source=govdelivery

Heartland Environmental Justice Center

https://heartlandej.org/?utm_medium=email&utm_source=govdelivery

October is Domestic Violence Awareness Month

https://www.dvawareness.org/1thing?utm_medium=email&utm_source=govdelivery

Education, Awareness & Screening - Liver Health Quiz

https://thinkliverthinklife.org/?utm_medium=email&utm_source=govdelivery Liver Health Quiz https://thinkliverthinklife.org/liver-health-quiz/?utm_medium=email&utm_source=govdelivery

Facebook Live: Childhood Irritability November 7, 2023 1:00–1:30 p.m. ET

https://www.nimh.nih.gov/news/events/announcements/facebook-live-childhood-irritability

Inappropriate Cardiac Imaging Triggers Too Many Alarms Ann Thomas, MD, MPH

https://www.medscape.com/viewarticle/997709

SGLT2 Inhibitors in Type 2 Diabetes Linked to Lower Risk of Developing GI Cancers Damian McNamara, MA

https://www.medscape.com/viewarticle/997718

NLM Invests in AI

NNLM Discovery | AI in the Scientific Landscape (Season 1/Episode 10)

How Naloxone Saves Lives in Opioid Overdose

Big lessons from small creatures Vision research with animal models is eye-opening

https://magazine.medlineplus.gov/article/big-lessons-from-small-creatures?utm_medium=email&utm_source=govdelivery

Partners in Cancer Research

https://www.cancer.gov/research/participate

Superbugs | SIDS | Long COVID | Hispanic Heritage | Cancer Clinical Trials

https://content.govdelivery.com/accounts/USNIH/bulletins/376a7fc?reqfrom=share

jueves, 26 de octubre de 2023

Senotherapeutics: a possible mitigator of age-related pulmonary disease eBioMedicine

https://www.thelancet.com/journals/ebiom/issue/vol96nonull/PIIS2352-3964(23)X0009-7

eBioMedicine in conversation with Alan Dangour on climate change and health

https://ebiomedicine.buzzsprout.com/1809873/13656247-alan-dangour-on-climate-change-and-health?utm_campaign=update-ebiom&utm_medium=email&_hsmi=279673225&_hsenc=p2ANqtz-8YOKrRN_lFh8DFdHHeIFDJUH6bamH5zAaLc5dHmkENExWhVIeCjT_Jt922ZruYxCQrh5cGDMpXWnFjtJyFGZu3bdT_0w&utm_content=279615669&utm_source=hs_email

Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00375-4/fulltext?dgcid=hubspot_update_feature_updatealerts_ebiom&utm_campaign=update-ebiom&utm_medium=email&_hsmi=279673225&_hsenc=p2ANqtz-9TJycVZiPbnDUaF6-0RaN2_Mgg8JHXmDJphgB9J597x7y6-OJ9mztaY07GQHJot8HsxN3r4Bgn7MvFzcDDulWUbkcgvw&utm_content=279615669&utm_source=hs_email

7 Things To Know About Complementary Health Approaches for Osteoarthritis

https://www.nccih.nih.gov/health/tips/things-to-know-about-complementary-health-approaches-for-osteoarthritis?nav=govd

How the Aging Brain Affects Thinking

https://www.nia.nih.gov/health/how-aging-brain-affects-thinking?utm_source=nia-eblast&utm_medium=email&utm_campaign=caregiving-20231026#changes

Massage Therapy: What You Need To Know

https://www.nccih.nih.gov/health/massage-therapy-what-you-need-to-know?nav=govd

Public policy and health in the USA miniseries: reimagining care for Americans with severe mental illness Thursday, November 02, 2023 6:00 PM Greenwich Mean Time

https://event.on24.com/wcc/r/4279771/2B8D6F4D66DDE367377872EC64A397AF?partnerref=hubspot_email_usmentalillness23_registration2&utm_campaign=usmentalillness23&utm_medium=email&_hsmi=279849763&_hsenc=p2ANqtz-8-qeZKywq6EUawNjhMSIaQT6f49r4BXSyKwr-_fxfDFkPCY5QaNgGtDL10qPYaolhPQ_vZ61ljKQGK4oLLFnOuyA0o8g&utm_content=279424330&utm_source=hs_email

Colorectal Cancer | Stories of Cancer Research | Stem Cell Transplant, 10/25/2023

https://content.govdelivery.com/accounts/USNIHNCI/bulletins/3775aac?reqfrom=share

Your patient with high Lp(a) may qualify for a clinical trial

https://www.amgentrials.com/study/?id=20180244 Study overview: Amgen Inc. is sponsoring a global, phase 3, double-blind cardiovascular outcomes study titled the OCEAN(a)-Outcomes Trial (The OCEAN(a) (Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction – Outcomes Trial) to compare the effect of treatment with with investigational drug olpasiran to placebo, on the risk for coronary heart disease death (CHD death), myocardial infarction, or urgent coronary revascularization in participants with atherosclerotic cardiovascular disease (ASCVD) and elevated lipoprotein(a). Participants will be randomly assigned to receive olpasiran or placebo administered by subcutaneous injection once every 12 weeks at the study site. The study drug will not replace any existing treatments that the patient may be receiving. The average follow-up duration will be around 4 years. The study is currently recruiting participants. Key study requirements: Adult patients receiving stable, optimized lipid-lowering therapy must have a history of myocardial infarction and/or percutaneous coronary intervention and an Lp(a) value of ≥ 200 nmol/L at screening by central laboratory.

Higher income and longer working years are linked to better mobility

https://www.nih.gov/news-events/news-releases/higher-income-longer-working-years-are-linked-better-mobility

Apply by Feb. 14: Funding to expand Alzheimer’s research infrastructure in Africa October 25, 2023

https://www.nia.nih.gov/research/blog/2023/10/apply-feb-14-funding-expand-alzheimers-research-infrastructure-africa?utm_source=NIA+Main&utm_campaign=8d05f3edc2-blog-AfricaAD&utm_medium=email&utm_term=0_-8180ce9847-%5BLIST_EMAIL_ID%5D

Therapeutic nanocarriers reduce lung inflammation in mice

Therapeutic nanocarriers reduce lung inflammation in mice

Understanding RNA-Modifying Enzymes: Q&A With Jeffrey Mugridge BY KIMBERLY ROUSSEAU

https://biobeat.nigms.nih.gov/2023/10/understanding-rna-modifying-enzymes-qa-with-jeffrey-mugridge/?utm_medium=email&utm_source=govdelivery

Investigating the Secrets of Cancer-Causing Viruses BY KIMBERLY ROUSSEAU

https://biobeat.nigms.nih.gov/2023/08/investigating-the-secrets-of-cancer-causing-viruses/?utm_medium=email&utm_source=govdelivery

Leishmania Parasite Uses Host Antibodies in Insect Vector’s Blood Meal to Breed

https://www.niaid.nih.gov/news-events/leishmania-parasite-uses-host-antibodies-insect-vectors-blood-meal-breed?utm_campaign=+58171553&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

miércoles, 25 de octubre de 2023

UK Biobank reveals: Mediterranean diet might be the key to combating 32 chronic diseases!

https://www.news-medical.net/news/20231025/UK-Biobank-reveals-Mediterranean-diet-might-be-the-key-to-combating-32-chronic-diseases!.aspx

What's really in your kombucha and kefir?

https://www.news-medical.net/news/20231024/Whats-really-in-your-kombucha-and-kefir.aspx

CROSS versus modified MAGIC or FLOT in oesophageal and gastro-oesophageal junction adenocarcinoma Peter S N van Rossum,Hanneke W M van Laarhoven

https://www.thelancet.com/journals/langas/issue/vol8no11/PIIS2468-1253(23)X0010-7

The Lancet Gastroenterology & Hepatology in conversation with Anna Emilie Kann on the causes of mortality in patients with alcohol-related liver disease

https://thelancetgastrohep.buzzsprout.com/1728646/13766613-anna-emilie-kann-on-the-causes-of-mortality-in-patients-with-alcohol-related-liver-disease?utm_campaign=update-langas&utm_medium=email&_hsmi=279662021&_hsenc=p2ANqtz-8YvhqpUKLs73TU4LDdns5sCn_Z98B1UYb_osMKBFlALRZALDyCe3mwRKcP2ZflK2k1QlWsRWwnWH0KCfn5QPzpHPRkfw&utm_content=279615079&utm_source=hs_email

Diagnosis and management of ectopic varices in portal hypertension

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00209-1/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsmi=279662021&_hsenc=p2ANqtz-8-c4rfG39lKbC6NUa1eF2zzF32yQ-VGL45f2rxBKtR_uX9XSdl9dSMhaeQzXx5uVqYBHj3ihqsrjKeJcEjpJQ7xpW9sQ&utm_content=279615079&utm_source=hs_email

Trimodality therapy versus perioperative chemotherapy in the management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction (Neo-AEGIS): an open-label, randomised, phase 3 trial

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00243-1/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsmi=279662021&_hsenc=p2ANqtz-_iZzZUd1QGaR7YW0vR8bVhcMLICwp1g3zOVJUq-QusinnZub5wpG8tHtIxWOUVIYSGAqb1MunrzrWun4V4odY6Af-Yyw&utm_content=279615079&utm_source=hs_email

Efficacy and safety of upadacitinib maintenance therapy for moderately to severely active ulcerative colitis in patients responding to 8 week induction therapy (U-ACHIEVE Maintenance): overall results from the randomised, placebo-controlled, double-blind, phase 3 maintenance study

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00208-X/fulltext?dgcid=hubspot_update_feature_updatealerts_langas&utm_campaign=update-langas&utm_medium=email&_hsmi=279662021&_hsenc=p2ANqtz--x-iyp4hZmgFJ5x4PEhviWGWClg6t7SLI6pQX-VyWZF7DQdrMrZeAhy97RV5kp-HZM_fqEcp6tn2q0OCKUbA6f8Um-4w&utm_content=279615079&utm_source=hs_email

My Research Can Help Protect You — and Your Company — From Hackers Trying to Steal Your Money and Information October 18, 2023 By: Shanée Dawkins

https://www.nist.gov/blogs/taking-measure/my-research-can-help-protect-you-and-your-company-hackers-trying-steal-your

Stay Safe and Secure Online During Cybersecurity Awareness Month — and All Year October 25, 2023

https://www.nist.gov/blogs/taking-measure/stay-safe-and-secure-online-during-cybersecurity-awareness-month-and-all-year

Psychedelic Therapy Tied to Reduced Depression, Anxiety Eve Bender

https://www.medscape.com/viewarticle/997652

Genetic Variation and Sickle Cell Disease Severity: A Systematic Review and Meta-Analysis

https://pubmed.ncbi.nlm.nih.gov/37851445/ From the abstract: " What genetic modifiers of sickle cell disease (SCD) are currently defined, and what are potential approaches to improve future studies? In this systematic review and meta-analysis of 571 studies examining 29?670 individuals with SCD, 17?757 associations involving 1552 genes and 25 SCD phenotype categories were discovered; of these, only 173 associations met the study design, reporting, and phenotype or genotype harmonization required for meta-analysis. Gene variants regulating fetal hemoglobin and a-thalassemia were frequently identified, but other associations remained unconfirmed."

Ovarian, Fallopian Tube, and Primary Peritoneal Cancers Prevention (PDQ®)–Health Professional Version

https://www.cancer.gov/types/ovarian/hp/ovarian-prevention-pdq?cid=eb_govdel#top

Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/kidney/hp/wilms-treatment-pdq?cid=eb_govdel#top

Childhood Cancer Genomics (PDQ®)–Health Professional Version

https://www.cancer.gov/types/childhood-cancers/pediatric-genomics-hp-pdq?cid=eb_govdel#top

Rectal Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/colorectal/hp/rectal-treatment-pdq?cid=eb_govdel#top

Colon Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/colorectal/hp/colon-treatment-pdq?cid=eb_govdel#top

Cervical Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/cervical/hp/cervical-treatment-pdq?cid=eb_govdel#top

How SARS-CoV-2 contributes to heart attacks and strokes

https://www.nih.gov/news-events/nih-research-matters/how-sars-cov-2-contributes-heart-attacks-strokes

Discrimination may lead to unhealthy gut-brain changes

https://www.nih.gov/news-events/nih-research-matters/discrimination-may-lead-unhealthy-gut-brain-changes

App aids early screening for autism

App aids early screening for autism https://www.nih.gov/news-events/nih-research-matters/app-aids-early-screening-autism

FDA approves ivosidenib for myelodysplastic syndromes

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-ivosidenib-myelodysplastic-syndromes?utm_medium=email&utm_source=govdelivery

Combining chemotherapy, trastuzumab, and immune-checkpoint inhibitors in HER2-positive gastro-oesophageal cancer

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02296-1/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278988838&_hsenc=p2ANqtz--GTMA7uVO9QrXRce1gnE5HIpy6HQQbp3RzGMq8TMcH83q_zqy9smEqSFJNwrmyy5_nrEvEVKJeXzeoTPfd6UcXTHIOzQ&utm_content=278988838&utm_source=hs_email

Pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma: interim analyses from the phase 3 KEYNOTE-811 randomised placebo-controlled trial

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02033-0/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278988838&_hsenc=p2ANqtz-8wTzVelhJBj6k77sbMF_wQzZKIKVsxf5yYy05PdrHoi_GdbTUTPTqh_4AvadmjFNbvY_C9nIGutPoIWouavZuzFuNStA&utm_content=278988838&utm_source=hs_email

Pembrolizumab as a first-line treatment for advanced gastric cancer

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00526-0/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278988838&_hsenc=p2ANqtz-8_l7lQgOsF3Y-QFY7NhSMG8p4YkEXYDb0s8wXvO8IUsiwu-8CVoKMMxqhvkhFdb28MlpUdLkhZJaF7lGQ3_cEhklfE_w&utm_content=278988838&utm_source=hs_email

Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for HER2-negative advanced gastric cancer (KEYNOTE-859): a multicentre, randomised, double-blind, phase 3 trial

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00515-6/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278988838&_hsenc=p2ANqtz-9wQJsP_kS7TZUagIKDcS96H3r9HDDV1SkB98sLrckASWySjvnjzvCkoo7jZHf1ZmTOuWvtogTwTWJ9qt3KGvc6ql9JJQ&utm_content=278988838&utm_source=hs_email

Neoadjuvant cemiplimab and surgery for stage II–IV cutaneous squamous-cell carcinoma: follow-up and survival outcomes of a single-arm, multicentre, phase 2 study

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00459-X/fulltext?dgcid=hubspot_email_conferencealerts_esmo23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278988838&_hsenc=p2ANqtz-_u2Yk8-AZ-WsGfoyShvBPKiXhkgwa5dL-dsEy32tjW49PqdL5lZ0kIxHrDzEpMgeLMe9z0ahAFjhKi4gN9QgWJXd6wJQ&utm_content=278988838&utm_source=hs_email

martes, 24 de octubre de 2023

SBRT Emerging as an Important Treatment for Early-Stage Kidney Cancer

https://www.cancer.gov/news-events/cancer-currents-blog/2023/kidney-cancer-localized-sbrt-radiation?cid=eb_govdel

SCARY TOXIC HALLOWEEN HAZARDS

Halloween Hazards: Scary Toxic By Ivanhoe Broadcast News on October 29, 2023 https://www.ivanhoe.com/?p=31551&preview=1&_ppp=c3a540abbb

CREEPY CRAWLEYS: HOW TO GET RID OF PESKY UNWANTED PESTS

Creepy Crawleys: How to Get Rid of Pesky Unwanted Pests By Ivanhoe Broadcast News on October 29, 2023 https://www.ivanhoe.com/?p=31548&preview=1&_ppp=d83ba757be

VITAMIN DEFICIENT? EAT YOUR WAY TO GOOD HEALTH

Vitamin Deficient? Eat Your Way to Good Health By Ivanhoe Broadcast News on October 28, 2023 https://www.ivanhoe.com/?p=31545&preview=1&_ppp=78c717e863

FIRST JOB FUNDAMENTALS: NAVIGATING DO’S AND DON’TS

First Job Fundamentals: Navigating Do’s and Don’ts By Ivanhoe Broadcast News on October 28, 2023 https://www.ivanhoe.com/?p=31542&preview=1&_ppp=9597534391

BLOOD CANCER: THE SILENT DISEASE

Blood Cancer: The Silent Disease By Ivanhoe Broadcast News on October 27, 2023 https://www.ivanhoe.com/?p=31595&preview=1&_ppp=de9d5eba78

IRREGULAR SLEEP DEADLY FOR THE HEART

Irregular Sleep Deadly for the Heart By Ivanhoe Broadcast News on October 26, 2023 https://www.ivanhoe.com/?p=31588&preview=1&_ppp=60ebf3463a

CARDIAC REHAB INCREASES BYPASS SURVIVAL

Cardiac Rehab Increases Bypass Survival By Ivanhoe Broadcast News on October 25, 2023 https://www.ivanhoe.com/?p=31582&preview=1&_ppp=649f407a6e

REDEFINING ALLERGY TREATMENT: MEDICINE’S NEXT BIG THING?

Redefining Allergy Treatment By Ivanhoe Broadcast News on October 24, 2023 https://www.ivanhoe.com/medical-breakthroughs/redefining-allergy-treatment/

SAVING HANNAH’S BRAIN: CORRECTING CHIARI MALFORMATION

Saving Hannah’s Brain: Correcting Chiari Malformation By Ivanhoe Broadcast News on October 23, 2023 https://www.ivanhoe.com/medical-breakthroughs/saving-hannahs-brain-correcting-chiari-malformation/

New insight into the immune response forges a path toward improved medical implants

New insight into the immune response forges a path toward improved medical implants

The Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative

https://braininitiative.nih.gov/

BRAIN Initiative Cell Census Network

https://braininitiative.nih.gov/research/tools-and-technologies-brain-cells-and-circuits/brain-initiative-cell-census-network

Brain Atlas Paves the Way for New Understanding of How the Brain Functions Posted on October 24th, 2023 by Lawrence Tabak, D.D.S., Ph.D.

https://directorsblog.nih.gov/2023/10/24/brain-atlas-paves-the-way-for-new-understanding-of-how-the-brain-functions/

FDA Calls for More Data on Dupilumab for Chronic Spontaneous Urticaria, Manufacturers Announce Marcia Frellick

https://www.medscape.com/viewarticle/997633?src=

Three Quarters of Menopausal Women Report Unexpected Symptoms Becky McCall October 23, 2023

https://www.medscape.com/viewarticle/997642?src=

Andexanet Improves Hemostasis in ICH Tied to Factor Xa Inhibitors Sue Hughes

https://www.medscape.com/viewarticle/997648?src=

COVID Coronary Plaque Infection Confirms CV Risk Sue Hughes and Allison Shelley

https://www.medscape.com/viewarticle/997638

Common Meds Link to Sudden Cardiac Arrest in Type 2 Diabetes Becky McCall

https://www.medscape.com/viewarticle/997629

lunes, 23 de octubre de 2023

Anxiety's impact: Young adults face cognitive and cardiovascular challenges

https://www.news-medical.net/news/20231022/Anxietys-impact-Young-adults-face-cognitive-and-cardiovascular-challenges.aspx

Does adding sugar to coffee and tea impact your lifespan? 32-year study reveals surprising results

https://www.news-medical.net/news/20231022/Does-adding-sugar-to-coffee-and-tea-impact-your-lifespan-32-year-study-reveals-surprising-results.aspx

Hormone levels tied to metabolic health in obesity

https://www.news-medical.net/news/20231022/Hormone-levels-tied-to-metabolic-health-in-obesity.aspx

Coffee and genetics: A complex blend impacting kidney health

https://www.news-medical.net/news/20231022/Coffee-and-genetics-A-complex-blend-impacting-kidney-health.aspx

COVID-19 tied to elevated risk of benign prostatic hyperplasia complications

https://www.news-medical.net/news/20231022/COVID-19-tied-to-elevated-risk-of-benign-prostatic-hyperplasia-complications.aspx

Novel GLP-1 receptor agonists offer hope for long-lasting diabetes treatment

https://www.news-medical.net/news/20231022/Novel-GLP-1-receptor-agonists-offer-hope-for-long-lasting-diabetes-treatment.aspx

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

https://www.news-medical.net/news/20231022/Everolimus-after-surgery-may-benefit-patients-with-very-high-risk-clear-cell-renal-cell-carcinoma.aspx

Ketamine's long-lasting antidepressant effects unveiled in new studyKetamine's long-lasting antidepressant effects unveiled in new study

https://www.news-medical.net/news/20231022/Ketamines-long-lasting-antidepressant-effects-unveiled-in-new-study.aspx

Short course of induction chemotherapy can reduce cervical cancer relapse and death by 35%

https://www.news-medical.net/news/20231022/Short-course-of-induction-chemotherapy-can-reduce-cervical-cancer-relapse-and-death-by-3525.aspx

Perioperative immunotherapy improves event-free survival in resectable early-stage lung cancer

https://www.news-medical.net/news/20231022/Perioperative-immunotherapy-improves-event-free-survival-in-resectable-early-stage-lung-cancer.aspx

Chemotherapy plus immunotherapy improves survival in patients with metastatic urothelial cancer

https://www.news-medical.net/news/20231022/Chemotherapy-plus-immunotherapy-improves-survival-in-patients-with-metastatic-urothelial-cancer.aspx

Metacognition and the pandemic: how our beliefs influence our choices

https://www.news-medical.net/news/20231023/Metacognition-and-the-pandemic-how-our-beliefs-influence-our-choices.aspx

Shedding light on the future of cognitive health in a graying world

https://www.news-medical.net/news/20231023/Shedding-light-on-the-future-of-cognitive-health-in-a-graying-world.aspx

New study reveals the impact of protein sources on health, environment, and economy

https://www.news-medical.net/news/20231023/New-study-reveals-the-impact-of-protein-sources-on-health-environment-and-economy.aspx

Director’s Innovation Speaker Series: Social Connection: An Eye to the Past, Present, and Future Date/Time: October 26, 2023, 2:00–3:00 p.m. ET

https://us06web.zoom.us/webinar/register/WN_KbVQHZsoTS-kMomtWQKW0A#/registration During this lecture, Julianne Holt-Lunstad, Ph.D., will discuss the health impacts of having or lacking social connection. The COVID-19 pandemic raised awareness about loneliness but also revealed gaps in our understanding of the individual and public health impacts of social connection. Dr. Holt-Lunstad will highlight the scope of the issue, evidence of health implications, and challenges and opportunities for translating this evidence into practical solutions and policy. https://www.nimh.nih.gov/about/connect-with-nimh

Glucagon-like peptide 1(GLP-1) receptor agonists in the management of the patient with type 2diabetes mellitus and chronic kidney disease: an approach for the nephrologist

https://www.sciencedirect.com/science/article/pii/S2013251423001475

The Effectiveness of Probiotics in Treating Food and Cow’s Milk Allergies among Pediatric Age Group: A Meta-analysis of Randomized Controlled Trials

https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3393

Effects of Early Diet on the Prevalence of Allergic Disease in Children: A Systematic Review and Meta-Analysis

https://www.sciencedirect.com/science/article/pii/S2161831323013893

The role of social capital in resilience among adolescents with adverse family environments

https://www.sciencedirect.com/science/article/pii/S1538544223000858

Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association

https://www.ahajournals.org/doi/10.1161/CIR.0000000000001184

domingo, 22 de octubre de 2023

Coffee consumption reduces risk of migraines, but not other neurological diseases

https://www.news-medical.net/news/20231020/Coffee-consumption-reduces-risk-of-migraines-but-not-other-neurological-diseases.aspx

Molecular Brain

https://molecularbrain.biomedcentral.com/

Liquid Biopsy at the Frontier of Early Detection, Prognosis and Cancer Treatments

https://molecular-cancer.biomedcentral.com/

Molecular mechanisms and therapeutic relevance of neuro-immune communication

https://molmed.biomedcentral.com/

Microbiome

https://microbiomejournal.biomedcentral.com/

Orphanet Journal of Rare Diseases

https://ojrd.biomedcentral.com/

Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial Kopczak et al.

https://www.thelancet.com/journals/laneur/home

Putting precursor haematological conditions centre stage The Lancet Haematology

https://www.thelancet.com/journals/lanhae/home

Antipsychotic dose reduction: unclear benefits but certain risks Stefan Leucht,Irene Bighelli,Spyridon Siafis,Johannes Schneider-Thoma,John M Davis Nov 2023 Volume 10Number 11p817-908, e28-e29

Antipsychotic dose reduction: unclear benefits but certain risks Stefan Leucht,Irene Bighelli,Spyridon Siafis,Johannes Schneider-Thoma,John M Davis Nov 2023 Volume 10Number 11p817-908, e28-e29 https://www.thelancet.com/journals/lanpsy/issue/current

Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00166-7/fulltext?dgcid=hubspot_email_conferencealerts_idweek23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278073229&_hsenc=p2ANqtz-9DFYQfpS45fTloCjfrX5vU_nN4SE0pz5LjBECvGQLilB5VgBIj8obMSqVv0qdY9QKEymuXQ6GlMdjhqFhJutg6LnYgdA&utm_content=278073229&utm_source=hs_email

COVID-19 Resource Centre

COVID-19 Resource Centre https://www.thelancet.com/coronavirus?dgcid=hubspot_email_conferencealerts_idweek23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278073229&_hsenc=p2ANqtz-9lzn4279Ar08jcGijz810tkwUdhPdEHAaWDuS1hiLqK6LHnmxG75dz24kFNdFU5CaVQsZncpGz8SgZNiiBAv0h4HKSeQ&utm_content=278073229&utm_source=hs_email Comparison of surveillance systems for monitoring COVID-19 in England: a retrospective observational study https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(23)00219-0/fulltext

sábado, 21 de octubre de 2023

Researchers aim to streamline brain surgery with a new soft robotic system

Researchers aim to streamline brain surgery with a new soft robotic system

Ophthalmology Research Seminar: Distinguished Speaker Series

https://ctvr.uci.edu/distinguished-speaker-series

Paths to excellence: nurturing talent through diversity

https://www.nei.nih.gov/about/news-and-events/news/paths-excellence-nurturing-talent-through-diversity

Stanford Medicine researchers build an eye ‘aging clock’ that could lead to treatments for ocular diseases

https://med.stanford.edu/news/all-news/2023/10/eye-aging-clock.html

FDA expands pediatric indication for entrectinib and approves new pellet formulation

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-expands-pediatric-indication-entrectinib-and-approves-new-pellet-formulation

Trial Results Confirm Effectiveness of Atezolizumab Against a Rare Sarcoma

https://www.cancer.gov/news-events/cancer-currents-blog/2023/atezolizumab-effective-alveolar-soft-part-sarcoma?cid=eb_govdel

Information for Your Patients: Know the Science of Complementary Health Approaches

https://www.nccih.nih.gov/health/providers/digest/know-the-science-of-complementary-health-approaches?nav=govdcd#information-for-your-patients

Know the Science of Complementary Health Approaches: What the Science Says

https://www.nccih.nih.gov/health/providers/digest/know-the-science-of-complementary-health-approaches-science?nav=govdcd

What Is Pneumonia? Fact Sheet

https://www.nhlbi.nih.gov/resources/what-pneumonia-fact-sheet

SBIR success story: diagnosing obstructive sleep apnea at home

https://www.nhlbi.nih.gov/news/2023/diagnosing-obstructive-sleep-apnea-home

Pregnant and Living with Sickle Cell Disease: A Push for Better Outcomes

https://www.nhlbi.nih.gov/news/2023/pregnant-and-living-sickle-cell-disease-push-better-outcomes

Childhood survivors of ARDS at risk for readmission

https://www.nhlbi.nih.gov/news/2023/childhood-survivors-ards-risk-readmission

Study finds higher alcohol intake increases fat deposits in heart, other body parts

https://www.nhlbi.nih.gov/news/2023/study-finds-higher-alcohol-intake-increases-fat-deposits-heart-other-body-parts

Look Out for Your Lungs: 5 Steps to Keep Your Lungs Healthy Infographic

https://www.nhlbi.nih.gov/resources/look-out-your-lungs-5-steps-keep-your-lungs-healthy-infographic

SARS-CoV-2 infects coronary arteries, increases plaque inflammation

https://www.nhlbi.nih.gov/news/2023/sars-cov-2-infects-coronary-arteries-increases-plaque-inflammation

Strategic Vision Refresh: Refreshing the NHLBI Strategic Vision

https://www.nhlbi.nih.gov/about/strategic-vision-refresh NHLBI is refreshing its Strategic Vision to address emerging scientific opportunities in accordance with new NIH strategic plan requirements. Help identify scientific priorities, make decisions, and allocate resources by sharing your input.

viernes, 20 de octubre de 2023

10th Annual Student Voice Competition

https://www.m4rd.org/ The Student Voice Prize is an international essay competition that raises the profile of rare diseases within the medical field, particularly among medical students, nurses and scientists. Beacon and Medics4RareDiseases host the competition and the winner will be published in The Orphanet Journal of Rare Diseases! https://www.rarebeacon.org/student-voice-prizes/the-student-voice-prize-2023/#:~:text=What%20is%20The%20Student%20Voice,rare%20diseases%20in%20their%20training.

Launch of HTx Patient Toolkit

https://www.htx-h2020.eu/for-patients/ As part of our work within the HTx Project, EURORDIS has developed the HTx Patient Toolkit - a series of resources and educational videos developed for advocates on health technology assessments (HTAs) and research conducted through the HTx project. François Houÿez, our Information & Access to Therapies Director, is among the instructors featured in the video series. https://www.htx-h2020.eu/

From Lab to Clinic: Translational Research for Rare Diseases

https://www.futurelearn.com/courses/introduction-to-translational-research-for-rare-diseases Welcome to EJP RD https://www.ejprarediseases.org/

European Rare Disease Research Coordination and Support Action consortium (ERICA)

https://download2.eurordis.org/Research%26Therapeutics/TherapeuticReportSummerEdition2023.pdf

Together4RD

https://together4rd.eu/ Along with our Together4RD project partners, Matt Bolz-Johnson, our Mental Health Lead and Healthcare Advisor, and Ines Hernando, our ERN and Healthcare Director, are among the co-authors who recently published a position statement calling for greater collaboration between European Reference Networks and industry.

Universal health coverage: expanding our ambition for health and well-being in a post-COVID world

https://download2.eurordis.org/publications/EURORDIS-RDI-Formal-Statement-for-HLM-on-UHC-2023.pdf

Gene therapies for rare diseases are under threat. Scientists hope to save them

https://www.nature.com/articles/d41586-023-03109-z

Mental Health & Wellbeing 28 Nov 2023 Brussels, Belgium

https://www.eurordis.org/mental-wellbeing/

Strategy, Advocacy & Partnering For The Global Orphan Drug Industry - 30 October 2023 | Pre-Congress Workshops (InterContinental Barcelona - next to Fira de Barcelona) 31 October - 2 November 2023 | Main Congress Days (Fira de Barcelona Montjuic)

https://www.terrapinn.com/conference/world-orphan-drug-congress/index.stm

Training for patient representatives and advocates on leadership and communication skills 26 October 2023 - 09:00 Gdańsk, Poland

https://www.ejprarediseases.org/event/training-for-patient-representatives-and-advocates-on-leadership-and-communication-skills-2/

Podcast: Rare on Air

https://www.eurordis.org/rare-on-air/ Should more diseases be screened for at birth? In our latest episode of Rare on Air, Julien Poulain talks to Iuliana Dumitriu, the mother of Victor, an eight-year-old boy living with Coffin-Lowry Syndrome in Romania. Iuliana, who is also the President of the Coffin-Lowry Syndrome Association shares with Julien her family’s story of the torturous, yet determined, seven-year journey toward receiving a diagnosis for Victor. Julien also explores the results of our recent Rare Barometer survey with our Social Research Director Jessie Dubief.

Gene Age Exhibition

https://geneage.asgent.org/o-projektu/ Gene Age Exhibition This month in Prague, the Association of Gene Therapy launched its Gene Age exhibition, accessible both in-person and online. The exhibition is aiming to heighten awareness and education regarding the impact of genes and their mutations in the development of human diseases, with a special focus on rare diseases. EURORDIS is a partner of the exhibition. https://asgent.org/

Take the EURORDIS Access Campaign Questionnaire

https://www.eurordis.org/access-campaign-questionnaire/ Treatment Access Have you completed the EURORDIS Access Campaign Questionnaire? We are inviting anybody living with a rare disease to share the difficulties they may be facing in accessing medicines, medical devices, surgeries, or medical consultations. The responses will help us uncover the hurdles to treatment that exist, toward the aim of improving access to treatments across Europe. Complete the questionnaire by 30 October.

Social Policy Action Group (SPAG)

https://www.eurordis.org/social-policy-action-group/ The Social Policy Action Group (SPAG) will support EURORDIS’ work to shape policies and practices that improve the access of people living with a rare disease and their families to holistic care, and the guarantee of their social and human rights.

SCREEN4CARE

https://www.eurordis.org/projects/screen4care/ Newborn Screening In Barcelona last week, Gulcin Gumus, our Senior Manager for Research & Policy, led a meeting of the Screen4Care Forum on Newborn Screening. With more than 40 rare disease experts and project partners in attendance, the meeting delved into various topics, including the challenges of newborn screening research versus implementing practices of screening at birth into national health systems.

Commission Communication on ‘A Comprehensive Approach to Mental Health’ Response from EURORDIS-Rare Diseases Europe On behalf of the 30 million people living with a rare disease in Europe

Mental Wellbeing On 28 November at the European Parliament in Brussels, EURORDIS and Mental Health Europe, as well as MEPs Sara Cerdas and Tilly Metz, will be hosting an event on the European Commission's recent Comprehensive Approach to Mental Health. The event will address how and why the Commission's Approach must support the mental health of individuals, including those with rare diseases, who face distinct challenges to their psychological wellbeing. https://download2.eurordis.org/publications/EURORDIS-Response-on-a-Comprehensive-Approach-to-Mental-Health.pdfv

Rare Disease Day Official Video 2023

The European Reference Networks: A vital, sensible, and successful investment

https://www.eurordis.org/erns-a-vital-sensible-and-successful-investment/

29 FEBRUARY is Rare Disease Day

https://www.rarediseaseday.org/

European Conference on Rare Diseases & Orphan Products (ECRD) 2024 will take place on 15-16 May 2024.

https://www.rare-diseases.eu/ The ECRD is recognised globally as the largest, patient-led rare disease policy event in which collaborative dialogue, learning and conversation takes place, forming the groundwork to shape goal-driven rare disease policies and allow for important and innovative discussions on a national and an international level to take place. Leading, inspiring and engaging all stakeholders to take action, the Conference is an unrivalled opportunity to network and exchange invaluable knowledge with over 1500 stakeholders in the rare disease community – patient advocates, policy makers, researchers, clinicians, healthcare professionals, healthcare industry representatives, academics, payers, regulators and Member State representatives. The next ECRD will take place as a fully hybrid conference on 15-16 May 2024, in Brussels and online!

New smartphone app quickly analyzes human motion to aid physical rehabilitation

https://www.nih.gov/news-events/news-releases/new-smartphone-app-quickly-analyzes-human-motion-aid-physical-rehabilitation

4 types of common anxiety disorders Anxiety affects millions of people in the United States alone. But not all types of anxiety or anxiety disorders are the same.

https://magazine.medlineplus.gov/pdf/Volume18Issue2-508.pdf

Anxiety: What you need to know Stressful or traumatic events and family history could increase your risk.

https://magazine.medlineplus.gov/article/anxiety-what-you-need-to-know

Olivia Culpo is speaking up for others with endometriosis

https://magazine.medlineplus.gov/article/olivia-culpo-is-speaking-up-for-others-with-endometriosis?utm_medium=email&utm_source=govdelivery When Olivia Culpo was on stage after winning both the Miss USA and Miss Universe pageants in 2012, she was in pain, but she didn’t know why. It wasn’t until years later that the model, actress, and fashion and beauty influencer found the cause of her pain and other symptoms. Endometriosis is an often painful disease where tissue that looks like the lining of the uterus grows in other places in

SCIENCE TRANSLATIONAL MEDICINE VOLUME 15|ISSUE 718|18 OCT 2023

https://www.science.org/toc/stm/15/718

Many potential pathways to future pandemic influenza

https://www.science.org/doi/full/10.1126/scitranslmed.adj2379?utm_campaign=+58108444&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

Scientists Discuss Prototype Pathogens for Pandemic Preparedness

https://www.niaid.nih.gov/news-events/scientists-discuss-prototype-pathogens-pandemic-preparedness?utm_campaign=+58110214&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

Moving Matters for My Health

https://www.cdc.gov/physicalactivity/activepeoplehealthynation/moving-matters.html?utm_medium=email&utm_source=govdelivery

jueves, 19 de octubre de 2023

Harmonisation of later-life cognitive function across national contexts: results from the Harmonized Cognitive Assessment Protocols

https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(23)00170-8/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhl&utm_campaign=update-lanhl&utm_medium=email&_hsmi=278876213&_hsenc=p2ANqtz-9t032gzXkV3XTA2C5YlOYsxXqfth5j2uuTUP3cmsiES27XQa5vhQ0qpr_i-OLH-hdqM60v-KHqXIcB73ccwH9SpX0xfw&utm_content=278511204&utm_source=hs_email

New pill helps COVID smell and taste loss fade quickly The antiviral drug ensitrelvir, which shortens sensory problems, is one of the few COVID-19 drugs available to people not at high risk of grave illness.

https://www.nature.com/articles/d41586-023-03244-7?utm_source=Live+Audience&utm_campaign=a0dbc783aa-briefing-dy-20231018&utm_medium=email&utm_term=0_b27a691814-a0dbc783aa-50432164

Variations in cardiovascular disease outcomes across Europe

https://www.thelancet.com/series/european-variations-CVD?dgcid=hubspot_update_feature_lanepecardiovasculardisease23&utm_campaign=update-lanepe&utm_medium=email&_hsmi=278887627&_hsenc=p2ANqtz-84IQ8aiJ9tgdDw2Dr5tUCah2zAXTvXfOAjPmJXA0JTav_r_QVm4Om73i441jwenbfnZfgrFP9vP6Lt9JF0OrEMKx5epA&utm_content=278511035&utm_source=hs_email

2022 High Throughput Imaging Characterization of Brain Cell Types and Co...

High Throughput Imaging Characterization of Brain Cell Types and Connectivity https://www.nimh.nih.gov/news/events/announcements/high-throughput-imaging-characterization-of-brain-cell-types-and-connectivity

Wellbeing Wednesdays: Episode 12 - Helping Students (and Adults) Address...

ENLACE Study Explores Colorectal Cancer in Hispanic and Latino People

https://www.cancer.gov/news-events/cancer-currents-blog/2023/colorectal-cancer-enlace-hispanic-latino?cid=eb_govdel The ENLACE study is the first to use cutting-edge technologies to describe the molecular features of colorectal tumors in Hispanic and Latino people. The study’s goals are to improve treatments and increase Hispanic/Latino engagement in cancer research.

A broad genetic test saved one newborn’s life. Research suggests it could help millions of others

https://apnews.com/article/genetic-testing-babies-newborns-whole-genome-cc27689e7f9deb88c9b0753d9cd0ba4b

The painful puzzle of diseases that have no name

https://www.bbc.com/future/article/20230807-undiagnosed-diseases-the-mysterious-syndromes-without-a-name

The Complete Human Y Chromosome Marks an Opportunity to Move Away from Stigma

https://www.scientificamerican.com/article/the-complete-human-y-chromosome-marks-an-opportunity-to-move-away-from-stigma/

For skeletal genomicist Carlos Ferreira, answers are in the bones

https://www.genome.gov/news/profile/for-skeletal-genomicist-carlos-ferreira-answers-are-in-the-bones

Cells Organize Themselves into ‘Neighborhoods’ That Could Shape Treatment “Cell atlases” offer an unprecedented look at how kidney cells be

https://www.scientificamerican.com/article/cells-organize-themselves-into-neighborhoods-that-could-shape-treatment/

The Clinical Geneticist Workforce: Challenges and Opportunities (Listeni...

Why Y took so long

20 Years After the Human Genome Project: G5 Leaders Reunite

NHGRI's Oral History Collection: Interview with Erich Jarvis

Human Gene Therapy VOLUME 34, ISSUE 17-18 / SEPTEMBER 2023

https://www.liebertpub.com/toc/hum/34/17-18?utm_campaign=HUM+FP+October+18%2C+2023+AD&utm_content=CTA-Button&utm_term=&utm_medium=email&utm_source=Adestra

6 Things To Know About Complementary Health Approaches for Rheumatoid Arthritis

https://www.nccih.nih.gov/health/tips/6-things-to-know-about-complementary-health-approaches-for-rheumatoid-arthritis?nav=govd

A Periodic Look at Elements BY RACHEL CROWLEY

https://biobeat.nigms.nih.gov/2023/10/a-periodic-look-at-elements/?utm_medium=email&utm_source=govdelivery Biomedical Beat Blog – National Institute of General Medical Sciences National Chemistry Week: Recent Interviews With NIGMS-Funded Chemists BY RACHEL CROWLEY https://biobeat.nigms.nih.gov/2022/10/national-chemistry-week-recent-interviews-with-nigms-funded-chemists/?utm_medium=email&utm_source=govdelivery

Pragmatic solutions to reduce the global burden of stroke

Anticoagulation in people with atrial fibrillation after intracranial haemorrhage

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00331-9/fulltext?dgcid=hubspot_email_conferencealerts_wsc23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278068144&_hsenc=p2ANqtz-_xKOys2xSH1TIEBtp_2McgwTqeRbaSo6qCOTxQpWEvmOdmfDqWUAJtFNqpEfFB5thxGzbDndz2PXP9_E7iDHgFmtBX9w&utm_content=278068144&utm_source=hs_email

Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00315-0/fulltext?dgcid=hubspot_email_conferencealerts_wsc23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278068144&_hsenc=p2ANqtz--Wj0_8GPPhOzRGbtLE-fliLPbmA4CyakYXv0QSNTZjsu3RbSxwGod5D6IMkcAITeOwLKVAz2WZn-JkSgkWi9VJiRhgow&utm_content=278068144&utm_source=hs_email

Thrombectomy for acute ischaemic stroke without advanced imaging

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02229-8/fulltext?dgcid=hubspot_email_conferencealerts_wsc23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278068144&_hsenc=p2ANqtz-_UaybgH8VcQtVT7RuzdTw2_qXmnzIhhkwJtRZwF4Clu0EjPUlH1fa15SU2O46QEeIGIvcNJzG8Xjkhk2-Fm3VugWlpQg&utm_content=278068144&utm_source=hs_email

Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02032-9/fulltext?dgcid=hubspot_email_conferencealerts_wsc23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278068144&_hsenc=p2ANqtz-_x1Aus-n5lz1fBh9_BHuaf3OBsUUlVsJdRLcCfi1G4soy9zLlhd6tg1vwXgpTAgNwUitnubmT8V-uk0p1sD4n3AFSvqA&utm_content=278068144&utm_source=hs_email

Pragmatic solutions to reduce the global burden of stroke: a World Stroke Organization–Lancet Neurology Commission

https://www.thelancet.com/commissions/global-burden-stroke?dgcid=hubspot_email_conferencealerts_laneurstroke23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278068144&_hsenc=p2ANqtz-_aIVU_wASKXCBvy9R6q83E0bUHASLLdy6wB0dfVa0DRCbH6S_msM1eCQcGP_9Mk5LdYIskZ_aIp3KKlW4NDKHMU4d99w&utm_content=278068144&utm_source=hs_email

miércoles, 18 de octubre de 2023

Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with cardiac arrest: a comparative meta-analysis and trial sequential analysis

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00137-6/fulltext?dgcid=hubspot_update_feature_updatealerts_lanres&utm_campaign=update-lanres&utm_medium=email&_hsmi=278714073&_hsenc=p2ANqtz-_Ycdrrzc6_RcjRKk34eeztv_3D98HR9__mK1fsHFqzVW7SqT979VeayWtTUlj5wk5yero4OEnwHnvqXtunzwv6D934hA&utm_content=278085462&utm_source=hs_email

Air pollution, climate change, and lung health in Europe The Lancet Respiratory Medicine

https://www.thelancet.com/journals/lanres/issue/vol11no10/PIIS2213-2600(23)X0010-1

Is low-risk status a surrogate outcome in pulmonary arterial hypertension? An analysis of three randomised trials

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00155-8/fulltext?dgcid=hubspot_update_feature_updatealerts_lanres&utm_campaign=update-lanres&utm_medium=email&_hsmi=278714073&_hsenc=p2ANqtz-8EgVgY-ZAzGR8G5Ie8X22G1wbEkR4PqdITl3hXrvBBDWgsQRtP_LNrXsO6cPm0HE5vDDXIfUdkhf0hDh0nulD0yjn52Q&utm_content=278085462&utm_source=hs_email

From profit to impact: lives saved and the future of RSV vaccine development

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00301-6/fulltext?dgcid=hubspot_update_feature_updatealerts_lanres&utm_campaign=update-lanres&utm_medium=email&_hsmi=278714073&_hsenc=p2ANqtz--us3Vtb9Y2HWjj8FR23uft9oCrUVPuhrGGyrgwXJpPuvMMHYzRRZQmt6wWGFXcfZAIQN4-Ov9IAxPmrRx7ipwmtjuMNw&utm_content=278085462&utm_source=hs_email

Pregnancy Registries

https://www.fda.gov/science-research/womens-health-research/pregnancy-registries?utm_medium=email&utm_source=govdelivery Pregnancy exposure registries are studies that collect health information on exposure to medical products such as drugs and vaccines during pregnancy.

FDA Takes Steps to Advance the Development of Novel Therapies for Stimulant Use Disorders

https://www.fda.gov/news-events/press-announcements/fda-takes-steps-advance-development-novel-therapies-stimulant-use-disorders?utm_medium=email&utm_source=govdelivery

Treating Migraines: Ways to Fight the Pain with Medication

https://www.fda.gov/consumers/consumer-updates/treating-migraines-ways-fight-pain-medication?utm_medium=email&utm_source=govdelivery

Breast Cancer Screening: Thermogram No Substitute for Mammogram

https://www.fda.gov/consumers/consumer-updates/breast-cancer-screening-thermogram-no-substitute-mammogram?utm_medium=email&utm_source=govdelivery

Pink Ribbon Guide - Mammography Matters

https://www.fda.gov/consumers/take-time-care-program/pink-ribbon-guide-mammography-matters?utm_medium=email&utm_source=govdelivery

OWH-Funded Research: Breast Cancer and Mammography

https://www.fda.gov/science-research/womens-health-research/owh-funded-research-breast-cancer-and-mammography?utm_medium=email&utm_source=govdelivery

Knowledge and News on Women: OWH Blog From the FDA Office of Women's Health

https://www.fda.gov/consumers/women/knowledge-and-news-women-owh-blog?utm_medium=email&utm_source=govdelivery

FDA OWH newsletter – October 2023: Spread the word about the importance of mammograms

https://www.fda.gov/consumers/women Bringing Clinical Research to Patients NOVEMBER 8, 2023 https://www.fda.gov/consumers/public-meetings-workshops-and-webinars/bringing-clinical-research-patients-11082023?utm_medium=email&utm_source=govdelivery

Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/kidney/hp/wilms-treatment-pdq?cid=eb_govdel#top

Childhood Soft Tissue Sarcoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/soft-tissue-sarcoma/hp/child-soft-tissue-treatment-pdq?cid=eb_govdel#top

Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/leukemia/hp/child-all-treatment-pdq?cid=eb_govdel#top

Research in Context: Obesity and metabolic health

The complexities of metabolism and body weight Losing weight and reversing obesity might seem straightforward: eat fewer calories than you burn. But that’s not as easy as it sounds. This special Research in Context feature explores the many factors that affect the body’s metabolism and weight, some of which are difficult to control. https://www.nih.gov/news-events/nih-research-matters/research-context-obesity-metabolic-health

martes, 17 de octubre de 2023

Possible tool discovered to diagnose common contributor to vascular dementia

https://keck.usc.edu/possible-tool-discovered-to-diagnose-common-contributor-to-vascular-dementia/

Combination immunotherapy in chemotherapy in gastric cancer Kazuhiro Shiraishi,Shun Yamamoto,Ken Kato

https://www.thelancet.com/journals/lanonc/issue/vol24no10/PIIS1470-2045(23)X0010-2

The Lancet Oncology in conversation with Wanda Cui on measuring ovarian toxicity

https://thelancetoncology.buzzsprout.com/1391338/13706364-wanda-cui-on-measuring-ovarian-toxicity?utm_campaign=update-lanonc&utm_medium=email&_hsmi=278524532&_hsenc=p2ANqtz--Hjh0s_nuTXFXmnaLhAvieSMdQ3_nmsl9LAD-whZciccZkX3sNM9_0HYhrzRYa4IIKsgrDnxpL1agmekHMPp5o2DAQkw&utm_content=278217911&utm_source=hs_email

Measuring ovarian toxicity in clinical trials: an American Society of Clinical Oncology research statement

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00390-X/fulltext?dgcid=hubspot_update_feature_updatealerts_lanonc&utm_campaign=update-lanonc&utm_medium=email&_hsmi=278524532&_hsenc=p2ANqtz-98jgJYHks4yvx62CCXVHjhhjKzkgXNpWVbVfOIVG5-AFss-gqMfnT1rW-v7ge6B_pQFuGL0bx38b8OwQnJf59gxLe9BQ&utm_content=278217911&utm_source=hs_email

Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy in patients with advanced ovarian cancer (OVHIPEC-1): final survival analysis of a randomised, controlled, phase 3 trial

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00396-0/fulltext?dgcid=hubspot_update_feature_updatealerts_lanonc&utm_campaign=update-lanonc&utm_medium=email&_hsmi=278524532&_hsenc=p2ANqtz-9zFhztbiHatbqfVdZMLvixbFg4frY-iMvGtWYYVHEewC3-nHdA-n6wc-lSR7FIClZytFeh2ORnT9oBT2q1nFHDFmkZnQ&utm_content=278217911&utm_source=hs_email

Can Bioprinted Skin Substitutes Replace Traditional Grafts for Treating Burn Injuries and Other Serious Skin Wounds? Posted on October 17th, 2023 by Lawrence Tabak, D.D.S., Ph.D.

https://directorsblog.nih.gov/2023/10/17/can-bioprinted-skin-substitutes-replace-traditional-grafts-for-treating-burn-injuries-and-other-serious-skin-wounds/

FDA Authorizes Updated Novavax COVID-19 Vaccine Formulated to Better Protect Against Currently Circulating Variants

https://www.fda.gov/news-events/press-announcements/fda-authorizes-updated-novavax-covid-19-vaccine-formulated-better-protect-against-currently?utm_medium=email&utm_source=govdelivery

The White House Gender Policy Council National Plan to End Gender-Based Violence: Strategies for Action

https://www.whitehouse.gov/wp-content/uploads/2023/05/National-Plan-to-End-GBV.pdf?utm_source=SAMHSA&utm_campaign=ad6eccb1bc-EMAIL_CAMPAIGN_2023_10_16_04_55&utm_medium=email&utm_term=0_-ad6eccb1bc-%5BLIST_EMAIL_ID%5D

Domestic Violence Awareness Month: SAMHSA’s Commitment to Raising Awareness and Hope for Survivors

https://www.samhsa.gov/blog/domestic-violence-awareness-month-samhsas-commitment-raising-awareness-hope-survivors?utm_source=SAMHSA&utm_campaign=ad6eccb1bc-EMAIL_CAMPAIGN_2023_10_16_04_55&utm_medium=email&utm_term=0_-ad6eccb1bc-%5BLIST_EMAIL_ID%5D

Gender-Based Violence and the Effects on Behavioral Health

https://www.samhsa.gov/gender-based-violence-behavioral-health?utm_source=SAMHSA&utm_campaign=ad6eccb1bc-EMAIL_CAMPAIGN_2023_10_16_04_55&utm_medium=email&utm_term=0_-ad6eccb1bc-%5BLIST_EMAIL_ID%5D

EASD 2023 – DiabetezZZ and Sleep: A Bidirectional Quandary

https://www.univadis.com/viewarticle/easd-2023-diabetezzz-and-sleep-bidirectional-quandary-2023a1000ory

Long-Term Graves' Disease Outcomes Suboptimal for Many

https://www.univadis.com/viewarticle/long-term-graves-disease-outcomes-suboptimal-many-2023a1000n9n?uac=148436CN&ecd=mkm_ret_231016_uni-OUS_SPECIAL_etid5210469&u=&utm_source=&utm_medium=email&utm_campaign=adhoc_ous_special-endo_20231016_ann-amer&utm_content=5210469&utm_term=&sso=true

Diagnosis Age Predicts Differentiated Thyroid Cancer Outcome

https://www.univadis.com/viewarticle/diagnosis-age-predicts-differentiated-thyroid-cancer-outcome-2023a1000org?uac=148436CN&ecd=mkm_ret_231016_uni-OUS_SPECIAL_etid5210469&u=&utm_source=&utm_medium=email&utm_campaign=adhoc_ous_special-endo_20231016_ann-amer&utm_content=5210469&utm_term=&sso=true

EASD 2023 – Is Metabolically Healthy Obesity a Thing?

https://www.univadis.com/viewarticle/easd-2023-metabolically-healthy-obesity-thing-2023a1000oz8?uac=148436CN&ecd=mkm_ret_231016_uni-OUS_SPECIAL_etid5210469&u=&utm_source=&utm_medium=email&utm_campaign=adhoc_ous_special-endo_20231016_ann-amer&utm_content=5210469&utm_term=&sso=true

EASD 2023 – Is Stringent Calorie Restriction the Answer for Long-Term Diabetes Remission?

https://www.univadis.com/viewarticle/easd-2023-stringent-calorie-restriction-answer-long-term-2023a1000oyc?uac=148436CN&ecd=mkm_ret_231016_uni-OUS_SPECIAL_etid5210469&u=&utm_source=&utm_medium=email&utm_campaign=adhoc_ous_special-endo_20231016_ann-amer&utm_content=5210469&utm_term=&sso=true

Insulin Sensitivity Fluctuates with Menstrual Cycle

https://www.univadis.com/viewarticle/insulin-sensitivityfluctuates-menstrual-cycle-2023a1000o2f?uac=148436CN&ecd=mkm_ret_231016_uni-OUS_SPECIAL_etid5210469&u=&utm_source=&utm_medium=email&utm_campaign=adhoc_ous_special-endo_20231016_ann-amer&utm_content=5210469&utm_term=&sso=true

SEPTEMBER 11, 2023 What Happens to Medicine in Your Body? BY RACHEL CROWLEY

https://biobeat.nigms.nih.gov/2023/09/what-happens-to-medicine-in-your-body/?utm_medium=email&utm_source=govdelivery

How Do Medicines Work? BY RACHEL CROWLEY

https://biobeat.nigms.nih.gov/2023/10/how-do-medicines-work/?utm_medium=email&utm_source=govdelivery

FDA approves neoadjuvant/ adjuvant pembrolizumab for resectable non-small cell lung cancer

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-neoadjuvant-adjuvant-pembrolizumab-resectable-non-small-cell-lung-cancer

lunes, 16 de octubre de 2023

Women, power, and cancer: a Lancet Commission Monday, November 13, 2023

https://event.on24.com/wcc/r/4254417/AB192BBF49789E49D22AF74ED0F8551F?partnerref=tlcom_lancetwebinarshub_lancetwomenpowercancer23 Women, power, and cancer: a Lancet Commission Nov 13, 2023 14:00 GMT / 9:00 EST Women, power, and cancer: a Lancet Commission was created to address urgent questions at the intersection of social inequality, cancer risk and outcomes, and the status of women in society. In this Lancet Webinar, authors of The Lancet Commission will summarise the key findings of the Commission, including cancer equity and gender transformative policies, cancer prevention in women, gender-responsive frameworks in the healthcare context, and the value of women in cancer economics.

Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00166-7/fulltext?dgcid=hubspot_email_conferencealerts_idweek23&utm_campaign=conferencealerts&utm_medium=email&_hsmi=278073512&_hsenc=p2ANqtz-9SjIsteKQckhBNN5pmk80V2aK_dHCvJ8COr1S9mxTV2nGSolsRguAJbVUBBh4C1TQmhnpfZ-GQ9hm93tDAh8cnwPixxw&utm_content=278073512&utm_source=hs_email

Directing vaccines to dendritic cells

Directing vaccines to dendritic cells Many cancer vaccines under investigation use mRNA to deliver key information to the immune system. But most of these trials do not effectively target dendritic cells, a key orchestrator of the immune response. Because dendritic cells display antigens on their surface, which activates other components of the immune system and sounds the alarm about a potential threat, they are an attractive target for cancer treatment strategies. With the ultimate goal of developing an improved vaccine strategy, a research team at Johns Hopkins University has designed a targeted, biodegradable nanoparticle that specifically delivers mRNA to dendritic cells. When evaluated in multiple mouse tumor models, treatment with the nanoparticles provided robust antitumor activity when combined with a type of therapy called immune checkpoint blockade. Their results were recently reported in the journal PNAS.

The Lancet Haematology in conversation with Meletios Dimopoulos on relapsed and refractory multiple myeloma

https://thelancethaematology.buzzsprout.com/1564352/13706562-meletios-dimopoulos-on-relapsed-and-refractory-multiple-myeloma?utm_campaign=update-lanhae&utm_medium=email&_hsmi=278408633&_hsenc=p2ANqtz--rVlgdFLgxerzq2nodtWXUfO79W4E3te_K-q4laEhIj-XTA_-TJrirAEXAClo3vf3mNZF7uWQzKlRWBo521qjVOFUi3Q&utm_content=278217566&utm_source=hs_email

Measuring chronic myeloid leukaemia TKI-related toxic effects in the real world: a systematic review and critical assessment of content validity of patient-reported outcome measures

https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00173-4/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhae&utm_campaign=update-lanhae&utm_medium=email&_hsmi=278408633&_hsenc=p2ANqtz-_oTkX24V86M68SBDgQuEoGIio9kPqr1DCKBPGW9KEdQQVoZMPvLrPNQNPLb8Q8hrRj9s6ltl9BNzl6dBMrVNUpcPyffQ&utm_content=278217566&utm_source=hs_email

Putting precursor haematological conditions centre stage

https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00282-X/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhae&utm_campaign=update-lanhae&utm_medium=email&_hsmi=278408633&_hsenc=p2ANqtz-_zP8huEWJhAnuCZfVR0u6HXAUC1R88kQ-Rix90OGVw-RrgPdfDv3SpThPqVD1mEJIWgVc0UVGzSME7W7cgoBLVUzCyAg&utm_content=278217566&utm_source=hs_email

Efficacy and safety of single-agent belantamab mafodotin versus pomalidomide plus low-dose dexamethasone in patients with relapsed or refractory multiple myeloma (DREAMM-3): a phase 3, open-label, randomised study

https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00243-0/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhae&utm_campaign=update-lanhae&utm_medium=email&_hsmi=278408633&_hsenc=p2ANqtz--x6omZF5yvaaI3YuX5CBcW014GS7CBvR_uF1gW3d1f3-VV_oXbgJ3PH-7yI9uBkoPxFzhwGCRFMfzl0p7LdLp9Vu_cSw&utm_content=278217566&utm_source=hs_email

FDA approves nivolumab for adjuvant treatment of Stage IIB/C melanoma

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-nivolumab-adjuvant-treatment-stage-iibc-melanoma?utm_medium=email&utm_source=govdelivery

Assessing Cardiac Contractility From Single Molecules to Whole Hearts

https://www.sciencedirect.com/science/article/pii/S2452302X23002966

Diabetes or obese pregnant women and their female offspring

https://www.sciencedirect.com/science/article/pii/S102845592300205X

Effects of fasciatherapy versus fascial manipulation on pain, range of motion and function in patients with chronic neck pain

https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-023-06769-0