An AI model decodes tumor mutations to predict treatment response Trained on more than 30,000 tumor genomes, MutationProjector offers drug developers a broader framework for connecting cancer genetics to therapy outcomes. Written byAndrea Corona

https://www.drugdiscoverynews.com/an-ai-model-decodes-tumor-mutations-to-predict-treatment-response-17197 Genetic sequencing has become a routine part of cancer care, but making clinical sense of the thousands of mutations found in a given tumor remains a stubborn challenge. A new AI model from researchers at University of California, San Diego (UC San Diego) is designed to close that gap — and it could have meaningful implications for how drug developers think about patient stratification and biomarker discovery.

Reminder: Informed Care in Psychiatric Medication Use and Withdrawal Webinar Wednesday, June 3, 2-3:30 p.m. ET

https://zoom.us/webinar/register/WN_A_RgmmwtTy2lY22iGnmvoA?utm_source=SAMHSA&utm_campaign=966130a5b6-EMAIL_CAMPAIGN_2026_05_11_01_40_COPY_01&utm_medium=email&utm_term=0_-a9ce11e3ce-167840245#/registration SAMHSA’s Office of the Chief Medical Officer will host a webinar titled “Informed Care in Psychiatric Medication Use and Withdrawal”. The event will feature Matthew Rudorfer, MD; Mark Horowitz, MD, PhD; and Laura Delano. The webinar will explore a range of psychiatric treatment options and strategies to support fully informed care, including understanding benefits, potential risks, dependence, and withdrawal considerations. Presenters will discuss emerging perspectives in the field, highlight current evidence, and examine approaches that promote collaborative decision-making between providers and patients. Following the presentations, attendees will have the opportunity to participate in a moderated question-and-answer segment. Questions will be addressed in the order received, with priority given to those submitted during registration. The webinar is open to all, but registration is required. Presenters: Matthew Rudorfer, M.D., is Chief of the Psychopharmacology, Somatic, and Integrated Treatments Research Program in the Treatment and Preventive Interventions Research Branch within the Division of Services and Intervention Research at the National Institute of Mental Health. Mark Horowitz, M.D., Ph.D., is an Associate Professor of Psychiatry at the University of Adelaide, a Visiting Lecturer in Psychopharmacology at King’s College London, and the lead of the National Psychotropic Deprescribing Clinic within the United Kingdom’s National Health Service. Laura Delano is an author, speaker, and consultant, and the founder of Inner Compass Initiative, a nonprofit organization that supports informed decision-making about psychiatric drugs and promotes non-medicalized approaches to human distress. In support of improving patient care, the Substance Abuse and Mental Health Services Administration is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide interprofessional collaborative continuing education (IPCE) activities for the healthcare team. IPCE activity credits are accepted as CME for medical practitioners, and CE for dieticians, nurses, pharmacists, physician associates/physician assistants, psychologists, and social workers. The activity was planned by and for the healthcare team. Please note: Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit. As a Jointly Accredited Organization, the Substance Abuse and Mental Health Services Administration is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit. Social workers completing this course receive 1.0 CEU continuing education credits. Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs. The views, opinions, and content expressed in this presentation do not necessarily reflect the views, opinions, or policies of the Substance Abuse and Mental Health Services Administration or the U.S. Department of Health and Human Services (HHS).

FDA approves pivekimab sunirine-pvzy for blastic plasmacytoid dendritic cell neoplasm, an ultra-rare hematologic malignancy

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-pivekimab-sunirine-pvzy-blastic-plasmacytoid-dendritic-cell-neoplasm-ultra-rare?utm_medium=email&utm_source=govdelivery

A Home for Every Child Innovation Challenge

The Administration for Children and Families (ACF) at the U.S. Department of Health and Human Services has announced a nationwide $7 million prize competition aimed at incentivizing states to improve their ratios of foster homes-to-children in foster care. This challenge supports ACF's "A Home for Every Child" initiative, which aims to right-size the ratio of available foster homes to the number of children in the foster care system nationwide. The objective is to recognize and reward states that demonstrate exceptional progress in increasing available foster homes relative to children in care, thereby advancing the goal of having homes waiting for children rather than children waiting for homes. These state performance-based bonuses reflect ACF’s commitment to achieving the goal of a 1:1 ratio of foster homes-to-children in foster care across the country. The Challenge Period is October 1, 2026 - September 30, 2027. https://acf.gov/home-every-child-innovation-challenge?utm_medium=email&utm_source=govdelivery

Understanding the Requirements for Sickle Cell Disease Comprehensive Systems of Care June 18, 2026: 2 - 3:30 PM ET / 1 - 2:30 PM CT

https://events.gcc.teams.microsoft.com/event/8433102f-32e8-479c-8970-466dea77048e@d58addea-5053-4a80-8499-ba4d944910df?utm_medium=email&utm_source=govdelivery Join the U.S. Department of Health & Human Services (HHS) Office of Minority Health (OMH) for Federal Resources and Efforts to Advance Sickle Cell Disease Comprehensive Systems of Care, part two of a roundtable series focused on advancing comprehensive systems of care for sickle cell disease (SCD). A comprehensive system of care for SCD offers multidisciplinary and specialized healthcare services to the SCD community throughout the lifespan. This webinar will provide information about available resources and specific efforts across HHS, and address challenges highlighted during Roundtable 1 in achieving sickle cell disease comprehensive systems of care.

Provisional Drug Overdose Death Counts +...

https://www.cdc.gov/nchs/nvss/vsrr/drug-overdose-data.htm?ACSTrackingID=DM155304&ACSTrackingLabel=Mental+Health%2C+Prevention%2C+and+the+Latest+Overdose+Data+&deliveryName=DM155304&utm_medium=email&utm_source=govdelivery The latest provisional data show 69,973 predicted overdose deaths for the 12-month period ending in December 2025 — about a 14% decrease compared with the same period ending in December 2024. Monthly provisional data suggest overdose deaths were relatively stable from September 2024 through July 2025, decreased in August and September 2025, and then leveled in October 2025. Most states saw decreases in predicted overdose deaths when comparing full-year 2025 with full-year 2024. However, several states — particularly in the Southwest and West — experienced increases during late 2024 and much of 2025.

HRSA Highlights Opportunities for Health Centers to Advance Nutrition-Focused Care to Prevent Chronic Disease U.S. Department of Health and Human Services Health Resources and Services Administration For Immediate Release May 13, 2026

https://www.hrsa.gov/about/news/press-releases/nutrition-care-prevent-chronic-disease?utm_medium=email&utm_source=govdelivery The Health Resources and Services Administration (HRSA) issued a Dear Colleague Letter encouraging more than 1,400 HRSA-funded health centers nationwide to expand efforts to promote proper nutrition as part of the Administration’s broader Make America Healthy Again (MAHA) initiative. Health centers are focused on addressing the root causes of illness and play a pivotal role in chronic disease prevention and treatment—assessing weight, providing nutrition counseling, and helping more than 32 million patients achieve better health outcomes, including control of their diabetes and hypertension.

Sickle Cell Disease - World Sickle Cell Day is June 19 +... +... +

https://minorityhealth.hhs.gov/sickle-cell-disease?utm_medium=email&utm_source=govdelivery World Sickle Cell Day is observed annually with the goal to increase public knowledge and an understanding of sickle cell disease, and the challenges experienced by patients and their families and caregivers. Sickle cell disease (SCD) is a complex group of inherited red blood cell disorders that can cause serious health complications such as pain crises, infections, and stroke. In individuals with SCD, the red blood cells become hard, sticky, and sickle (crescent) shaped, which can block blood flow in small blood vessels. SCD affects about 100,000 people in the United States, the majority of whom are black or African American. This year, the U.S. Department of Health and Human Services’ (HHS) call for a healthier Nation highlights the importance of chronic disease prevention and health promotion, emphasizing the need to address high rates of chronic illness through a range of solutions, including the critical role of food and nutrition. High quality nutrition is essential for individuals living with sickle cell disease (SCD) as it supports their immune system, overall health, and disease management. High-quality nutrition can make a meaningful difference in the lives of people living with SCD. https://minorityhealth.hhs.gov/news/promoting-good-nutrition-people-sickle-cell-disease?utm_medium=email&utm_source=govdelivery Learn about the importance of a healthy diet for those living with SCD and view easy to make nutrient-dense recipes. https://minorityhealth.hhs.gov/news/promoting-good-nutrition-people-sickle-cell-disease?utm_medium=email&utm_source=govdelivery#recipes

What is MyHealthfinder? Trusted information to help your family stay healthy. +... +...

https://odphp.health.gov/myhealthfinder?utm_medium=email&utm_source=govdelivery The Harms of Screen Use https://www.hhs.gov/surgeongeneral/reports-and-publications/screen-use-harms/index.html?utm_medium=email&utm_source=govdelivery Harmful screen use among children and adolescents has become a public health concern. With support from schools, communities, and governments, together we can shift the cultural norms around screens and help our children be healthier and happier nationwide.

Men's Health Week: June 14-21, 2026 +++...+...

https://odphp.health.gov/healthypeople/objectives-and-data/browse-objectives/men?utm_medium=email&utm_source=govdelivery Healthy People 2030 focuses on improving men's health. Men live an average of 5 years less than women, often dying from preventable or treatable chronic disease related outcomes such as heart disease, cancer, diabetes, and stroke. Men are at higher risk than women for many serious diseases, including heart disease, lung cancer, and HIV. Men also face unique health problems that don’t affect women, like prostate cancer. https://www.cdc.gov/chronic-disease/prevention/index.html?utm_medium=email&utm_source=govdelivery To improve men’s health, it’s important to raise awareness about preventive screenings and regular health care for men of all ages. Early detection and treatment, connection and support, and taking preventive steps now can improve health outcomes for men. Interventions to reduce smoking and drinking and promote healthy behaviors also can help prevent diseases and improve men’s health. https://menshealthmonth.org/?utm_medium=email&utm_source=govdelivery This year’s theme —“Partners in Care: For Better Lifespans Across the Lifespan” emphasizes that men’s health does not happen in isolation and highlights the role that families, communities, and care partners play in supporting healthier outcomes for men. Fostering men's health throughout the lifespan helps improve outcomes not only for men, but for their families and communities as well. This year, in honor of Men's Health month, consider wearing blue on Fridays in June to show support for men's mental and physical health and encourage the men in your life to seek preventive care. https://menshealthmonth.org/wp-content/uploads/2026/03/Mens-Health-Month-2026-toolkit-compress.pdf?utm_medium=email&utm_source=govdelivery