Aporte a la rutina de la trinchera asistencial donde los conocimientos se funden con las demandas de los pacientes, sus necesidades y las esperanzas de permanecer en la gracia de la SALUD.
miércoles, 1 de abril de 2026
Using RNA to treat heart attacks
https://www.nih.gov/news-events/nih-research-matters/using-rna-treat-heart-attacks
Using RNA to treat heart attacks
At a Glance
An RNA-based lipid nanoparticle therapy helped the heart recover from a heart attack in animal studies.
The results suggest a new strategy for treating heart attacks and repairing damage to the heart.
Scientists identify proteins tied to food tolerance
https://www.nih.gov/news-events/nih-research-matters/scientists-identify-proteins-tied-food-tolerance
Scientists identify proteins tied to food tolerance
At a Glance
Scientists identified parts of proteins that interact with immune cells and allow mice to tolerate certain foods rather than have an allergic reaction.
The findings enhance our current understanding of food tolerance and may lead to new therapies for people with food allergies.
SuperAgers show unique cell signatures in the brain
https://www.nih.gov/news-events/nih-research-matters/superagers-show-unique-cell-signatures-brain
At a Glance
Researchers linked neuron creation to exceptional recall and memory in older adults.
Understanding how new neurons are created in adulthood could help lead to interventions that promote healthy aging.
April is Move More Month! Kick off April by celebrating National Walking Day on April 1!
https://www.heart.org/en/-/media/Healthy-Living-Files/Fitness/Move_More_Toolkit.pdf?sc_lang=en&utm_medium=email&utm_source=govdelivery
National Walking Day is April 1.
https://www.heart.org/en/healthy-living/fitness?utm_medium=email&utm_source=govdelivery
Want to Learn More about the Health Benefits of Physical Activity?
Explore the Physical Activity Guidelines for Americans!
https://odphp.health.gov/our-work/nutrition-physical-activity/physical-activity-guidelines/about-physical-activity-guidelines?utm_medium=email&utm_source=govdelivery
Physical activity is key to improving the health of the nation. Based on the latest science, the Physical Activity Guidelines for Americans is a flagship resource for health professionals and policymakers that provides recommendations on how everyone can improve their health through regular physical activity.
Learn ways to help people understand the benefits of physical activity and how to make it a part of their regular routine.
Adults need at least 150 minutes of moderate-intensity aerobic activity, like brisk walking or fast dancing, each week. Adults also need muscle-strengthening activity, like lifting weights or doing push-ups, at least 2 days each week.
Youth ages 6 through 17 need at least 60 minutes of moderate-to-vigorous activity to attain the most health benefits from physical activity. They also need activities that make their muscles and bones strong, like climbing on playground equipment, playing basketball, and jumping rope.
Move more and sit less. There is a strong relationship between increased sedentary behavior and increased risk of heart disease, high blood pressure, and all-cause mortality. All physical activity, especially moderate-to-vigorous activity, can help offset these risks.
Any amount of physical activity has some health benefits. Americans can benefit from small amounts of moderate-to-vigorous physical activity spaced throughout the day.
Activity can have immediate health benefits. For example, physical activity can reduce anxiety and blood pressure and improve quality of sleep and insulin sensitivity. It can also help manage conditions that Americans already have. For example, physical activity can decrease pain for those with osteoarthritis, reduce disease progression for hypertension and type 2 diabetes, reduce symptoms of anxiety and depression, and improve cognition for those with dementia, multiple sclerosis, ADHD, and Parkinson’s disease.
Check out resources to help Move Your Way!
https://odphp.health.gov/our-work/nutrition-physical-activity/move-your-way-community-resources?utm_medium=email&utm_source=govdelivery
World Health Assembly 2026 Seventy-ninth World Health Assembly 18–23 May 2026
https://www.who.int/about/governance/world-health-assembly
World Health Assembly. Geneva, Switzerland | 18-23 May 2026
Rare Diseases Forum 2026 21 April 2026
https://events.theparliamentmagazine.eu/event/rare-diseases-forum/
The Rare Diseases Forum 2026 comes at a crucial time for EU health policy. With over 30 million Europeans affected, momentum is growing for a more coordinated response. In 2025, the European Parliament called for a comprehensive EU Action Plan on Rare Diseases, urging stronger Member State commitment. Upcoming reforms to EU pharmaceutical law and the HTA regulation will reshape access to orphan drugs.
Meanwhile, initiatives like the European Health Data Space (EHDS), European Partnership on Rare Diseases (ERDERA), and Joint Action for Rare Diseases Research and Innovation (JARDIN) aim to drive progress in research, diagnosis, and care. As these efforts advance, key challenges remain – especially around access, innovation, and cross-border collaboration. What policy levers must the EU activate now to ensure no patient is left behind?
European Health Data Space Regulation (EHDS)
https://health.ec.europa.eu/ehealth-digital-health-and-care/european-health-data-space-regulation-ehds_en
One year after entering into force on 26 March 2025, the European Health Data Space (EHDS), part of the European Strategy for Data, has moved into its implementation phase. Work is underway to establish governance, technical standards and infrastructure for cross-border health data sharing, with the aim of enabling access to and use of primary and secondary health data across the EU.
For people living with rare diseases, the EHDS could be transformative by supporting earlier diagnosis and accelerating research and access to new therapies. While still at an early stage, initiatives such as HealthData@EU and EU-funded projects like TEHDAS2 are beginning to lay the foundations for more harmonised data use.
With key implementing acts expected by March 2027, the coming year will be critical for advancing the rollout of the EHDS. EURORDIS also looks forward to participating in a consultation session on 12 May with Commissioner for Health Olivér Várhelyi as part of the Commission’s Implementation Dialogue on the European Health Data Space.
https://tehdas.eu/
EURORDIS’ response to the Midterm Review of the European Strategy for the Rights of Persons with Disabilities 2021-2030 February 2026
EURORDIS’ response to the Midterm Review of the European Strategy for the Rights of Persons with Disabilities 2021-2030
February 2026
EURORDIS Response: The EU Strategy for the Rights of Persons with Disabilities 2021-2030. A contribution prepared by EURORDIS and the members of its Social Policy Action Group (SPAG)
EURORDIS, in collaboration with the members of its Social Policy Action Group (SPAG), has published its response to the European Commission’s midterm review of the European Strategy for the Rights of Persons with Disabilities 2021-2030.
https://www.eurordis.org/publications/midterm-review-of-european-strategy-rights-of-persons-with-disabilities-response/
Adéla Odrihocká, rare disease advocate and member of EURORDIS’ Social Policy Action Group (SPAG), met with the European Commissioner for Equality, Hadja Lahbib, on 20 March during a Youth Policy Dialogue, contributing to discussions shaping the future of the EU Strategy for the Rights of Persons with Disabilities. The exchange highlighted the importance of ensuring that the voices of people living with disabilities are reflected in EU policymaking.
https://www.linkedin.com/in/ad%C3%A9la-odrihock%C3%A1-855091198/
https://www.linkedin.com/in/hadja-lahbib/
Within a working group, Adéla highlighted key barriers to employment, including the lack of cross-border recognition of disability status, limited access to support services, and inaccessible recruitment processes. These priorities align with EURORDIS’ recent contribution, developed with the Social Policy Action Group, to the European Commission’s midterm review of the Strategy for the Rights of Persons with Disabilities. The contribution calls for improved disability assessment and recognition across Member States, stronger support for independent living, and a more effective EU Disability Card.
According to findings published last year from a EURORDIS’ Rare Barometer survey, eight in 10 people living with a rare disease also live with a disability.
https://www.eurordis.org/rare-barometer-findings-daily-life-survey/
REGULATION OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL
Proposal for a REGULATION OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL amending Regulations (EU) 2017/745 and (EU) 2017/746 as regards simplifying and reducing the burden of the rules on medical devices and in vitro diagnostic medical devices, and amending Regulation (EU) 2022/123 as regards the support of the European Medicines Agency for the expert panels on medical devices and Regulation (EU) 2024/1689 as regards the list of Union harmonisation legislation referred to in its Annex I
https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52025PC1023
The European Commission has finalised translations of its proposals to revise the EU’s Medical Devices Regulation (MDR) and In Vitro Diagnostic Medical Devices Regulation (IVDR), allowing formal discussions to begin in the European Parliament and the Council. These regulations set the rules for how medical devices – including diagnostic tests, implants and digital health tools – are assessed and approved for use in the EU.
Policymakers have signalled their intention to move quickly, although no clear timeline for agreement has been set. The Cypriot Presidency has emphasised the need to simplify the regulatory framework while maintaining safety and quality standards.
Changes to the IVDR could support the development and availability of specialised diagnostic tests, helping to shorten the diagnostic journey. Revisions to the MDR could also improve access to innovative assistive and therapeutic technologies, and orphan devices.
EURORDIS welcomes European Parliament draft report calling for a European Action Plan on Rare Diseases March 2026
https://www.eurordis.org/response-draft-proposal-for-action-plan/
EURORDIS welcomes European Parliament draft report calling for a European Action Plan on Rare Diseases
March 2026
5 March 2026, Brussels – EURORDIS–Rare Diseases Europe welcomes the draft report presented by MEP Nicolás González Casares, Member of the European Parliament Committee on Public Health (SANT), calling on the European Commission to propose legislation establishing a European Rare Disease Action Framework.
DRAFT REPORT with recommendations to the Commission on a European Union rare disease action plan (2025/2130(INL)) Committee on Public Health Rapporteur: Nicolás González Casares
https://www.europarl.europa.eu/doceo/document/SANT-PR-785192_EN.html
On 2 March, MEP Nicolás González Casares presented a draft own-initiative legislative report to the European Parliament’s Public Health (SANT) Committee, calling on the European Commission to propose legislation establishing a European framework for rare diseases. The report highlights that, among the 6,000 to 8,000 identified rare diseases affecting an estimated 27 to 36 million people in the EU, around 95% still lack an authorised treatment.
The report calls for a comprehensive approach addressing the full rare disease pathway, including improved coordination of research, faster and more equitable diagnosis, better access to therapies, strengthened support for patients and families, and enhanced data sharing, notably through the European Health Data Space. It also emphasises the need to reduce inequalities across Member States and reinforce the role of the European Reference Networks.
EURORDIS welcomed the report as an important step forward in the long-standing effort to establish an EU Action Plan for Rare Diseases. “We are very happy with this draft report, which reflects a growing recognition in Europe that rare diseases cannot be addressed through fragmented national policies alone. The scale of the challenge demands a coordinated European approach,” said Valentina Bottarelli, Head of Policy & Public Affairs at EURORDIS.
MEPs on the SANT Committee had until 26 March to submit amendments to the draft report. A vote in Committee is expected in June, followed by a plenary vote in the European Parliament, likely in September.
Olivér Várhelyi presents Biotech Act I to parliamentary committee
https://control.eup.glcloud.eu/content-manager/content-page/20260319-1100-COMMITTEE-SANT?audio=fr&lang=fr&logo=true&multicast=true
On 19 March, during a joint meeting of the SANT and ITRE committees, Commissioner for Health and Animal Welfare, Olivér Várhelyi, presented part one of the Biotech Act, followed by an exchange with Members. Published in December 2025, Biotech Act I aims to strengthen Europe’s biotechnology and biomanufacturing sectors by supporting innovation, simplifying regulatory frameworks and boosting investment.
The discussion highlighted growing concerns about Europe’s declining competitiveness in biotechnology, particularly in clinical trial activity. The EU’s global share has fallen from 18% to 9%, while China’s has risen to around 30%.
The proposed Act seeks to address these challenges by accelerating clinical trial approvals, especially for multi-country trials, streamlining regulatory procedures, and promoting the use of health data and artificial intelligence. It also aims to close the investment gap, with the European Investment Bank expected to mobilise up to €10 billion to support biotech scale-ups.
MEPs also stressed the decline in the share of orphan medicines developed by EU-based companies, reinforcing calls to strengthen Europe’s capacity to deliver innovative treatments more rapidly and equitably across Member States.
The next steps include committee reports (by both SANT and ITRE), that will shape the Parliament’s position, while the Council carries out its own parallel examination.
https://ec.europa.eu/info/law/better-regulation/have-your-say/initiatives/14627-Biotech-Act_en
Ending the diagnostic odyssey: How Europe can lead the way in rare disease diagnosis March 2026
Ending the diagnostic odyssey: How Europe can lead the way in rare disease diagnosis
March 2026
For many people living with rare diseases, the hardest part of their illness isn’t the treatment. It’s the wait for a diagnosis. Symptoms appear. Appointments follow. Tests are run. Specialists are consulted. And still, for what can be years, there are no answers.
https://www.eurordis.org/how-europe-can-lead-way-rare-disease-diagnosis/
EURORDIS supports EU Member States’ efforts to secure reintroduction of health NGOs’ operating grants March 2026
EURORDIS supports EU Member States’ efforts to secure reintroduction of health NGOs’ operating grants
March 2026
4 March 2026, Brussels – EURORDIS–Rare Diseases Europe, together with fellow members of the EU4Health Civil Society Alliance, reiterates its call for the European Commission to reinstate operating grants for health non-governmental organisations, as political momentum grows among EU Member States for their return from 2026 onwards.
https://www.eurordis.org/eurordis-supports-member-states-efforts-operating-grants-reintroduction/
martes, 31 de marzo de 2026
Quantum techniques offer a glimpse of next-generation medicine Quantum-informed AI could open up unexplored chemical space, speeding the design of safer, more effective drugs.
https://www.drugdiscoverynews.com/quantum-techniques-offer-a-glimpse-of-next-generation-medicine-16815?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_4ohn1Rh86Av1dDd0FclJngmb4vJcSCDvwFCGHTDv0t2qqa-Y_7B2H0XhFnA5e4EIZfpZ9XwBpgMuvndjA3peWoJcEIw&_hsmi=411298769&utm_content=411298769&utm_source=hs_email
Today, QSimulate, a biotech software company that develops quantum-informed simulation tools, announced a new round of financing that brings its total funding to over $11 million and simultaneously unveiled QUELO v2.3, the latest version of its quantum-enabled molecular simulation platform. The news signals that quantum mechanics is rapidly moving from a theoretical aspiration to a practical engine for pharmaceutical innovation.
How multi-omics is redefining proteomics and precision discovery
Transcriptomics, proteomics, and functional genomics are converging to create a new era of mechanism-aware drug discovery.
https://www.drugdiscoverynews.com/how-multi-omics-is-redefining-proteomics-and-precision-discovery-16791?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_CI5s9FiP73vK25wn3IYJ_J-amkWWuiEZQDxecuNV7ldcj_YyNbuNA6ccYhDhkcRDZQWEDBTt8SHJzMDV17FLPf0SM2Q&_hsmi=411298769&utm_content=411298769&utm_source=hs_email
After two decades dominated by genomics, the field’s attention has shifted toward understanding how genetic blueprints translate into functional, dynamic proteins — and how those proteins interact, fold, misfire, or evolve in the complex environment of living cells. Proteomics is now taking center stage and becoming the connective tissue that links the cell’s instructions to its outcomes.
The growing role of multi-omics within drug discovery Harnessing multi-omics and AI, researchers are transforming drug discovery by revealing disease mechanisms, pinpointing therapeutic targets, and speeding up development.
https://www.drugdiscoverynews.com/the-growing-role-of-multi-omics-within-drug-discovery-17097
Drug discovery has long been a high-risk, high-reward endeavor. Developing a new therapeutic from initial concept to market approval can take over a decade and cost more than $2 billion on average. Despite these staggering investments, the failure rate remains high, with many drugs faltering in late-stage clinical trials due to unforeseen toxicity, lack of efficacy, or poor patient stratification. Traditional approaches often focus on targeting a single molecule or pathway, an approach increasingly recognized as insufficient for tackling complex diseases such as cancer, neurodegeneration, and autoimmune disorders.
The future of gene therapy depends on mastering in vivo delivery At the Advanced Therapies conference, industry leaders showcased how in vivo CAR T cell and gene delivery innovations could transform accessibility and clinical outcomes.
https://www.drugdiscoverynews.com/the-future-of-gene-therapy-depends-on-mastering-in-vivo-delivery-17102
Over the past decade, chimeric antigen receptor (CAR) T cell therapy has emerged as one of the most transformative innovations in cancer treatment, harnessing the immune system’s power to target and eliminate malignant cells. By redirecting patient-derived T cells to recognize specific antigens, CAR T therapies have achieved remarkable success in hematologic malignancies, particularly in refractory disease.
Making it easier for patients living with rare diseases to find the right specialist
https://rarerevolutionmagazine.com/making-it-easier-for-patients-living-with-rare-diseases-to-find-the-right-specialist/
For people living with rare diseases, the longest and most difficult delays often happen before treatment ever begins.
Rare disease journeys are rarely linear. Patients and caregivers may spend years navigating uncertainty, misdiagnosis and fragmented care before they ever reach the right clinician. Research suggests that, on average, it can take five or more years1 to receive an accurate rare disease diagnosis, during which time they may see six physicians2 or more. Along the way, misdiagnosis and fragmented care are well documented, often contributing to worse outcomes and eroding trust in the healthcare system.
Editorial Barriers to accessing cataract surgery The Lancet Healthy Longevity +++ +...
The effects of daily low-dose aspirin on white matter hyperintensity lesions and retinal vascular calibre in healthy older adults: the ENVIS-ion exploratory neuroimaging substudy of the ASPREE randomised clinical trial
Walter P Abhayaratna, MBBS PhDa,b walter.p.abhayaratna@act.gov.au ∙ Prof Christopher M Reid, PhDb,d ∙ Katherine L Webb, MAb ∙ Prof Rory Wolfe, PhDb ∙ Ruth E Trevaks, PhDb ∙ Liubov Robman, MBBS PhDb,e ∙ et al.
https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(25)00134-5/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhl&utm_campaign=update-lanhl&utm_medium=email&_hsenc=p2ANqtz--zIz2SCHv_JS90wY-2JYIAs8iqp3y80XIm0VLktWi2SOQZN9I8FYx-c099OqzWDwWf582Ndo3NBVlbI8rZgbHh2wCTWg&_hsmi=411201548&utm_content=410953304&utm_source=hs_email
Responsible use of artificial intelligence in the provision of long-term care for older people: a care-centric approach
Caroline Emmer De Albuquerque Green, PhDa caroline.green@philosophy.ox.ac.uk ∙ Tyler Reinmund, MScb ∙ Prof Kate Hamblin, PhDc ∙ Prof Samir K Sinha, MD DPhil
https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(26)00001-2/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhl&utm_campaign=update-lanhl&utm_medium=email&_hsenc=p2ANqtz-_L4JYEd33RwlU_VUJyC5UMOP8p-3pgcNllNpZ1Eu5wnjuMkfn41-XvgbdUcJPUazvGwL83hhrFVtoYfyEz3sAskM7KvA&_hsmi=411201548&utm_content=410953304&utm_source=hs_email
The impact of exercise interventions on domains of quality of life in women diagnosed with breast cancers during chemotherapy treatment: a meta-analytic review
LaShae D Rolle, MPHa,b,c lashaerolle@miami.edu ∙ Soyeon Ahn, PhDd ∙ Elle M Mezzio, BSb,c ∙ Madalyn Wheeler, MSEdb,c,d ∙ Loren Yavelberg, PhDb,c ∙ Carmen J Calfa, MDb,c ∙ et al.
https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(26)00003-6/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhl&utm_campaign=update-lanhl&utm_medium=email&_hsenc=p2ANqtz--dhHUuFFT9ni9JYRTz5N2JLMMxV5WzNkRAJ2B3HrfBSC3mS3-JN88OGU3U0fHm-0JWeDinugppvOqJms3y27uU3OibzQ&_hsmi=411201548&utm_content=410953304&utm_source=hs_email
Editorial
Barriers to accessing cataract surgery
The Lancet Healthy Longevity
https://www.thelancet.com/journals/lanhl/issue/vol7no2/PIIS2666-7568(26)X2002-5
Winners of the Nutrition for OUR Immune System Health (NOURISH): Autoimmunity Challenge
https://orwh.od.nih.gov/in-the-spotlight/winners-of-nutrition-for-our-immune-system-health-nourish-autoimmunity-challenge
Led by the NIH Office of Autoimmune Disease Research (OADR), the Nutrition for OUR Immune System Health (NOURISH): Autoimmunity Challenge was a national crowdsourcing competition designed to generate innovative ideas that integrate diet and nutrition into autoimmune disease research.
Coronary revascularisation before TAVI Philippe Garot p.garot@angio-icps.com ∙ Mariama Akodad ++
Deferral of percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation (PRO-TAVI): an investigator-initiated, multicentre, open-label, non-inferiority, randomised controlled trial
Prof Ronak Delewi, MD PhDa,* r.delewi@amsterdamumc.nl ∙ Hugo M Aarts, MDa,b,* ∙ Gijs M Broeze, MSca ∙ Kimberley I Hemelrijk, MDa ∙ Dirk Jan van Ginkel, MDc ∙ Geert A A Versteeg, MDe ∙ et al. Free to access with registration until Apr 7, 2026
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00308-9/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_acc26&_hsenc=p2ANqtz-_3mlxlMg1UlBG4DuiH6LXi6Ch8HrrnXN570nvN5kAou7F6N3JjsfZwrQODYwA3iom_YXQlY9YBp9xV3rzdRgHw4bMZyQ&_hsmi=411295032&utm_content=411295032&utm_source=hs_email
Coronary revascularisation before TAVI
Philippe Garot p.garot@angio-icps.com ∙ Mariama Akodad Free to access with registration until Apr 7, 2026
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00597-0/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_acc26&_hsenc=p2ANqtz-_gc9tT5zjNUUmpNgwIxwnljq5srA8rHcAPWT4hcb9cQQ4vQfE8W6nNNhY47JBrpcyuy11qQM0IPjCkptpWeP1Stl0ltQ&_hsmi=411295032&utm_content=411295032&utm_source=hs_email
The promise of telesurgery in oncology The Lancet Oncology ++ ++...
Benmelstobart plus anlotinib versus pembrolizumab as first-line treatment for PD-L1-positive, advanced non-small-cell lung cancer (CAMPASS): a blinded, randomised, controlled, phase 3 trial
Hua Zhong, MDa,* ∙ Jing Wang, MMb,* ∙ Runxiang Yang, MMc,* ∙ Yongzhong Luo, BMd,* ∙ Wei Zuo, MMe,* ∙ Wei Zhang, MDa,* ∙ et al.
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(26)00049-5/abstract?dgcid=raven_jbs_etoc_feature_lanonc
A practical toolkit with recommendations for analysing and visualising patient-reported outcomes in early phase dose-finding oncology trials (OPTIMISE-AR)
Emily Alger, BSc MMathStata ∙ Antoine Regnault, PhDb ∙ Amylou C Dueck, PhDc ∙ Madeline Pe, PhDd ∙ Michael J Grayling, PhDe ∙ Melanie J Calvert, PhDf,g,h,i,j,k ∙ et al.
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(26)00018-5/abstract?dgcid=raven_jbs_etoc_feature_lanonc
The promise of telesurgery in oncology
The Lancet Oncology
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(26)00134-8/fulltext?dgcid=raven_jbs_etoc_email
Apr 2026
Volume 27Number 4p393-526, e170-e231
https://www.thelancet.com/journals/lanonc/issue/vol27no4/PIIS1470-2045(26)X2003-4
Editorial e475 Tuberculosis at a crossroads The Lancet Global Health +++ +... +...
Effects of climate change on physical inactivity: a panel data study across 156 countries from 2000 to 2022
Christian García-Witulski, PhDa,b,c christian_garcia@uca.edu.ar ∙ Mariano Rabassa, PhDa ∙ Oscar Melo, PhDd ∙ Juliana Helo Sarmiento, PhD
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(25)00472-3/fulltext?dgcid=hubspot_update_feature_updatealerts_langlo&utm_campaign=update-langlo&utm_medium=email&_hsenc=p2ANqtz--nrLnyfvFa9IrUOejpTRRLUmyrWlLMAuYg32VtLCtjGBy-cH0096ijK-0IG9_ma22OrURKmF7rrqfFq2f3dQIHJ8ZQBw&_hsmi=411358359&utm_content=410961029&utm_source=hs_email
Global climate justice and the future of air quality co-benefits in low-income and middle-income countries: an energy, climate, and health modelling study
Noah Scovronick, PhDa,* scovronick@emory.edu ∙ Jinyu Shiwang, MSb,c,d,* ∙ Maddalena Ferranna, PhDe,* ∙ Fabian Wagner, PhDf,* ∙ Frank Errickson, PhDg,* ∙ Dan Tong, PhDh ∙ et al.
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(26)00006-9/fulltext?dgcid=hubspot_update_feature_updatealerts_langlo&utm_campaign=update-langlo&utm_medium=email&_hsenc=p2ANqtz-_x-AX4M_Tn886taki0oK0D6NTrDf0zMtuDY734F3zcm3R-M2T1jnsT28fbii7BSxL1JlU79EAdcHjZXmZtL2anXasCyQ&_hsmi=411358359&utm_content=410961029&utm_source=hs_email
Prevalence estimates of small vulnerable newborns in China (2012–22): a modelling study
Yanxia Xie, MPHa,† ∙ Prof Juan Liang, MDa,b,† ∙ Yi Mu, PhDa,† ∙ Peiran Chen, PhDa ∙ Prof Yanping Wang, MDa,c ∙ Zheng Liu, MSa ∙ et al.
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(25)00498-X/fulltext?dgcid=hubspot_update_feature_updatealerts_langlo&utm_campaign=update-langlo&utm_medium=email&_hsenc=p2ANqtz-9Vh7IMoe320K2RP9L1ALbaffunWhCqIsAT7b1qZiG2Zb66rE_0h2eETCxbMspmxLpiEsFjnUNstN4LaoQDWXoC9wApTQ&_hsmi=411358359&utm_content=410961029&utm_source=hs_email
Energy and health in low-income and middle-income countries
https://www.thelancet.com/series-do/energy-health-2026?dgcid=hubspot_update_feature_langloenergyhealth26&utm_campaign=update-langlo&utm_medium=email&_hsenc=p2ANqtz-9KW474Xtnv224j6_iEH1ZUpb9NxM8Xe9m-qodLhZYF0v86JHqN6Pp1H1ZYKjY2gdQHkpvoL_BbSiwLXAKxovRPLC_UlQ&_hsmi=411358359&utm_content=410961029&utm_source=hs_email
Reliable and affordable clean energy is essential for modern living and powering economies. Access to clean energy has increased substantially in low-income and middle-income countries over the past three decades. However, millions still lack reliable and affordable access to electricity and clean cooking fuels. This new Series—an update to the Series published in The Lancet in 2007—outlines the burden of disease associated with energy production and consumption; the drivers of and barriers to clean energy adoption; and how reliable, affordable, sustainable, and equitable electricity access in health-care facilities is necessary for achieving universal health coverage.
Apr 2026
Volume 14Number 4e475-e667
https://www.thelancet.com/journals/langlo/issue/vol14no4/PIIS2214-109X(26)X2002-2
Education and health equity: diverse learning needs in the modern era The Lancet Regional Health – Western Pacific ++... +
Education and health equity: diverse learning needs in the modern era
The Lancet Regional Health – Western Pacific
https://www.thelancet.com/journals/lanwpc/article/PIIS2666-6065(26)00050-7/fulltext?dgcid=raven_jbs_etoc_feature_lanwpc
Mar 2026
Volume 68
https://www.thelancet.com/journals/lanwpc/issue/vol68nonull/PIIS2666-6065(26)X2001-6
Major risk factors of obesity in China and recommendations for future prevention and control efforts: a systematic review and meta-analysis
Jiajin Hua,b,c,u ∙ Jinchen Xied,e,u ∙ Borui Liua,b,u ∙ Wen Pengf ∙ Buyun Liug ∙ Yinkun Yanh ∙ et al.
https://www.thelancet.com/journals/lanwpc/article/PIIS2666-6065(26)00037-4/fulltext?dgcid=raven_jbs_etoc_feature_lanwpc
Surveillance or Surgery for Low-Risk Ductal Carcinoma in Situ Sara Freeman Medscape Europe March 31, 2026
Non-Risk-Based Lung Cancer Screening Tied to Better Survival Liam Davenport March 31, 2026
lunes, 30 de marzo de 2026
Plastic Detox documentary claims the microplastic in your brain can make a spoon. The latest science says that’s ridiculous Brian Buntz | R & D World | March 30, 2026
https://geneticliteracyproject.org/2026/03/30/plastic-detox-documentary-claims-the-microplastic-in-your-brain-can-make-a-spoon-the-latest-science-says-thats-ridiculous/
Last year, we wrote about how a decimal-point error and selective framing turned black plastic spatulas into a public-health scare. Now Netflix’s The Plastic Detox is amplifying another over-the-top claim: that the human brain may contain enough microplastic to make a plastic spoon. That line traces to a February 2025 Nature Medicine paper from researchers at the University of New Mexico. In postmortem frontal cortex samples collected in 2024, the authors reported a median microplastic concentration of 4,917 µg/g, or roughly 0.49% by weight. Scale that to an average brain and you get a visually irresistible metaphor.
Raw milk myth wake-up call Hayley Philip | March 30, 2026
https://geneticliteracyproject.org/2026/03/30/raw-milk-myth-wake-up-call/
Once again, raw milk is everywhere: in Instagram reels, wellness podcasts, farmer-to-consumer marketplaces, and even policy debates. It’s being framed as ancestral, clean, immune-boosting, and somehow more “real” than the milk most of us grew up drinking. With about 4.4% of U.S. adults, or about 11 million people, have reported drinking raw milk at least once a year, despite repeated safety warnings; that’s why we’re revisiting this topic now.
GLP-1 Drugs Gain Ground in Cardiovascular Prevention Brian Owens March 09, 2026
GLP-1 Drugs Gain Ground in Cardiovascular Prevention
Brian Owens
https://www.medscape.com/viewarticle/glp-1-drugs-gain-ground-cardiovascular-prevention-2026a1000759?ecd=mkm_ret_260329_mscpmrk_cardio_top-content_etid8221053&uac=148436CN&impID=8221053
March 09, 2026
TRENDING WITH ALLERGISTS +++ +++ +
TRENDING WITH ALLERGISTS
Early Risk Factors for Food Allergy Uncovered
Early Skin and Respiratory Allergies Predict Food Allergy, Study Finds
Lara Salahi
https://www.medscape.com/viewarticle/early-skin-and-respiratory-allergies-predict-food-allergy-2026a10007ae?ecd=mkm_ret_260330_mscpmrk_allergy_top-content_etid8218795&uac=148436CN&impID=8218795
March 10, 2026
GLP-1 Adverse Effects: Practical Tips for Clinicians
GLP-1 Adverse Effects: Practical Tips for Clinicians
Kevin Fernando, MBChB
https://www.medscape.com/viewarticle/1003255?ecd=mkm_ret_260330_mscpmrk_allergy_top-content_etid8218795&uac=148436CN&impID=8218795
March 18, 2026
Allergy Affects 1 in 4 With Immunodeficiency
Allergy Affects 1 in 4 With Common Variable Immunodeficiency
Edited by Archita Rai
https://www.medscape.com/viewarticle/allergy-affects-1-4-common-variable-immunodeficiency-2026a100090y?ecd=mkm_ret_260330_mscpmrk_allergy_top-content_etid8218795&uac=148436CN&impID=8218795
March 25, 2026
Panel Endorses Early Introduction of These Food Allergens
Expert Panel Endorses Early Introduction of Potential Food Allergens
Heidi Splete
https://www.medscape.com/viewarticle/expert-panel-endorses-early-introduction-potential-food-2026a100084j?ecd=mkm_ret_260330_mscpmrk_allergy_top-content_etid8218795&uac=148436CN&impID=8218795
March 17, 2026
Drug Approved for Allergic Fungal Rhinosinusitis
Dupilumab Approved for Allergic Fungal Rhinosinusitis
Mia Sims
https://www.medscape.com/viewarticle/dupilumab-approved-allergic-fungal-rhinosinusitis-2026a10005zi?ecd=mkm_ret_260330_mscpmrk_allergy_top-content_etid8218795&uac=148436CN&impID=8218795
February 25, 2026
JAK Inhibitor Safe for Kids’ Atopic Dermatitis: New Data
Data Support Ruxolitinib’s Safety for Kids’ Atopic Dermatitis
Heidi Splete
https://www.medscape.com/viewarticle/data-support-ruxolitinibs-safety-kids-atopic-dermatitis-2026a10008i4?ecd=mkm_ret_260330_mscpmrk_allergy_top-content_etid8218795&uac=148436CN&impID=8218795
March 20, 2026
SLIT Appears Safe and Effective for Dust Mite Allergy
Sublingual Immunotherapy Appears Safe and Effective for House Dust Mite-Induced Allergic Rhinoconjunctivitis
Edited by Mandeep Singh Rawat
https://www.medscape.com/viewarticle/sublingual-immunotherapy-appears-safe-and-effective-house-2026a10007m7?ecd=mkm_ret_260330_mscpmrk_allergy_top-content_etid8218795&uac=148436CN&impID=8218795
March 12, 2026
Bipolar Disorder: Assessment and Management Source: National Institute for Health and Care Excellence Published December 07, 2020 Updated September 11, 2025
https://reference.medscape.com/cc2/p10/bipolar-disorder-assessment-and-management-2022a10018nh?ecd=mkm_ret_260330_mscpmrk-OUS_ExcNews_etid8219594&uac=148436CN&impID=8219594
Bipolar Disorder Is Not a Mood Disorder
Stephen M. Strakowski, MD; Sheri L. Johnson, PhD
https://www.medscape.com/viewarticle/bipolar-disorder-not-mood-disorder-2025a10010ss?ecd=mkm_ret_260330_mscpmrk-OUS_ExcNews_etid8219594&uac=148436CN&impID=8219594
December 31, 2025
LAIs vs Oral Antipsychotics for Bipolar I Rehospitalization
Edited by Sneha Gupta
https://www.medscape.com/viewarticle/lais-vs-oral-antipsychotics-bipolar-i-rehospitalization-2026a100083g?ecd=mkm_ret_260330_mscpmrk-OUS_ExcNews_etid8219594&uac=148436CN&impID=8219594
March 17, 2026
Sex Differences May Affect Schizophrenia, Bipolar Outcomes
Edited by Anushree Chaphalkar
https://www.medscape.com/viewarticle/sex-differences-may-affect-schizophrenia-bipolar-outcomes-2025a1000ojh?ecd=mkm_ret_260330_mscpmrk-OUS_ExcNews_etid8219594&uac=148436CN&impID=8219594
September 17, 2025
Visuomotor processing in the superior colliculus Elí Lezama [1] , Mario Treviño* [1]
https://www.academia.edu/academia-neuroscience-and-brain-research/1/2/10.20935/AcadNeurosci8046
The superior colliculus (SC) is an evolutionarily conserved midbrain structure that maintains a consistent laminar organization across most mammalian species. This architecture reflects shared functional requirements for visual processing, attentional control, and motor coordination. Physiological studies confirm that the SC can process visual information independently of the primary visual cortex (V1), sustaining visuomotor behaviors through subcortical networks following V1 lesion or inactivation. This capacity illustrates how alternative neural pathways can maintain essential survival-related functions without cortical involvement. Comparative approaches reveal both conserved operational principles and species-specific adaptations. In rodents, SC activity guides attentional allocation, perceptual selection, and adaptive decision-making based on visual cues. In primates, its extensive connectivity with cortical and subcortical structures supports target selection, saccade generation, and sensorimotor integration. Collectively, these findings establish the SC as a fundamental substrate for adaptive signal processing that links perception with action across diverse behavioral contexts. This review synthesizes current understanding of the mammalian SC, focusing on its roles in visual processing, attention, and motor coordination. By synthesizing evidence across species, we describe how conserved neural architecture contributes to adaptive perception and behavior, and how the SC complements cortical pathways in shaping visually guided actions.
https://www.academia.edu/journals/academia-neuroscience-and-brain-research/articles?source=journal-top-nav
domingo, 29 de marzo de 2026
Allergens
https://www.niehs.nih.gov/health/topics/agents/allergens
Information on allergens, asthma, and pulmonary research performed at NIEHS | Additional resources for managing allergies
Blood test predicts start of Alzheimer’s disease symptoms
https://www.nih.gov/news-events/nih-research-matters/blood-test-predicts-start-alzheimers-disease-symptoms
At a Glance
Researchers developed an Alzheimer’s “clock” that uses a blood test to roughly predict the onset of Alzheimer’s disease symptoms.
The ability to predict symptom onset could aid in the selection of clinical trial participants and might one day enable improved decision-making for patients.
Editorial Action on infection needs grounding in the social sciences The Lancet Microbe +++ +...
Artesunate–pyronaridine–atovaquone–proguanil and artesunate–fosmidomycin–clindamycin compared with standard artesunate–pyronaridine for the treatment of uncomplicated malaria (MultiMal): a randomised, controlled, clinical, phase 2 trial in Gabon and Ghana
Jean Claude Dejon Agobé, MD PhDa,∗ ∙ Oumou Maïga-Ascofaré, MSc PhDb,c,d,∗ ∙ Prof Ayôla Akim Adegnika, MD PhDa,e,f ∙ Christoph Pfaffendorfg ∙ Joseph Marfo Boaheng, MPhil PhDb ∙ Jean Ronald Edoa, MDa ∙ et al
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00173-9/fulltext?dgcid=hubspot_update_feature_updatealerts_lanmic&utm_campaign=update-lanmic&utm_medium=email&_hsenc=p2ANqtz-8xsKpC86wMF1MhqB_tX-vzRPyvQ-ld6OR3EiCYocCVd3mgnd88parhqsOxZ8GaBu8urardl2hpoZ7_hC8EHqREvZbqng&_hsmi=410352390&utm_content=410106867&utm_source=hs_email
Spatiotemporal patterns of Rift Valley fever virus in Africa: a retrospective genomic epidemiology and phylodynamic modelling study
John Juma, PhDa,b ∙ Houriiyah Tegally, PhDc ∙ Samson L Konongoi, BVetMeda,d ∙ Kristina Roesel, PhDa ∙ Prof Rosemary Sang, PhDd ∙ Prof Tulio de Oliviera, PhDc ∙ et al.
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00179-X/fulltext?dgcid=hubspot_update_feature_updatealerts_lanmic&utm_campaign=update-lanmic&utm_medium=email&_hsenc=p2ANqtz-_g-N6Q_foVQkt0pwoha6oetqv6zkkE-k8tB0NOlesXViiBTHtPbeUTjdpdn1YDiSqPyLGddbQ6daPjwHftysMo_J9zRg&_hsmi=410352390&utm_content=410106867&utm_source=hs_email
Bedaquiline resistance in patients with Xpert MTB/RIF Ultra-tested rifampicin-resistant tuberculosis in the Western Cape, South Africa: a prospective study
Janré Steyn, MSca ∙ Jennifer Williams, MSca ∙ Fahd Naufal, MDb ∙ Jason Limberis, PhDb ∙ Melanie Grobbelaar, PhDa ∙ Nabila Ismail, PhDa ∙ et al.
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00221-6/fulltext?dgcid=hubspot_update_feature_updatealerts_lanmic&utm_campaign=update-lanmic&utm_medium=email&_hsenc=p2ANqtz--M8-jjZdiHwzVLBCX-lIM3JABqr07sHqiwdkwnthwAPsOm_HB3vxE0llcmCtXd75zVL-YWY3fxHXPBZAHaPNVGhD6Kng&_hsmi=410352390&utm_content=410106867&utm_source=hs_email
Editorial
Action on infection needs grounding in the social sciences
The Lancet Microbe
https://www.thelancet.com/journals/lanmic/issue/vol7no3/PIIS2666-5247(26)X2002-X
The risks of AI-generated health advice eClinicalMedicine ++ ++...
Development of an early prediction model for endometriosis risk: the simplified adolescent factors for endometriosis (SAFE) score
Gita D. Mishraa g.mishra@uq.edu.au ∙ Mohammad Reza Baneshia ∙ Sally Mortlocka ∙ Grant W. Montgomeryb ∙ Jenny Dousta ∙ Annette J. Dobsona ∙ et al.
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00053-2/fulltext?dgcid=raven_jbs_etoc_feature_eclinm
Dapiglutide, a dual GLP-1 and GLP-2 receptor agonist, for obesity: a randomised, double-blind, placebo-controlled parallel-group, proof-of-concept trial
Casper K. Nielsena ∙ Thorir G. Pálssona ∙ Julie L. Formanb ∙ Michaela Lukacovab ∙ Benjamin A.H. Jensenc ∙ David S. Mathiesena ∙ et al
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00048-9/fulltext?dgcid=raven_jbs_etoc_feature_eclinm
The risks of AI-generated health advice
eClinicalMedicine
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00098-2/fulltext?dgcid=raven_jbs_etoc_email
Mar 2026
Volume 93
https://www.thelancet.com/journals/eclinm/issue/vol93nonull/PIIS2589-5370(26)X2002-8
Intensive LDL cholesterol-lowering shows major benefits for heart disease patients
https://www.news-medical.net/news/20260328/Intensive-LDL-cholesterol-lowering-shows-major-benefits-for-heart-disease-patients.aspx
Using cholesterol-lowering medications more intensively to achieve a more aggressive target for low-density lipoprotein cholesterol (LDL-C) reduced the rate of major cardiovascular events by one-third among patients with atherosclerotic cardiovascular disease (ASCVD), according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).
Energy’s long game: thermogenic adipocytes and the metabolic diseases of modern life Silvia Corvera* [1] , Michael P. Czech [1]
https://www.academia.edu/2837-4010/4/1/10.20935/AcadBiol8131
The ability to generate, store, and mobilize energy is fundamental to life, and disruptions in these processes underlie metabolic disease. This review examines how these mechanisms evolved to rely profoundly on lipids, a large family of molecules that serve an unusually wide range of biological functions. From early evolutionary times, lipids have enabled chemiosmotic energy transduction, organized the endomembrane systems that synthesize and package neutral lipids, served as concentrated reservoirs of metabolic energy, and functioned as signaling molecules that coordinate cellular and systemic physiology. Adipocytes are specialized cells that can accumulate large amounts of lipid within specialized lipid droplet organelles. Over evolutionary time, mammals developed distinct adipocyte subtypes with tailored physiological roles. White adipocytes, characterized by a single large unilocular lipid droplet, coordinate energy storage and release in response to systemic cues. In contrast, the role of brown and beige adipocytes is to protect the organism from cold exposure by generating heat as a primary output of UCP1-mediated mitochondrial uncoupling. Crucially, this thermogenic process requires extensive systemic coordination: sympathetic neural input triggers lipolysis, vascular networks deliver fuel from multiple adipose depots, and hormonal signals integrate metabolic demand across organs. These requirements position thermogenic adipocytes as metabolic integration “nodes” that orchestrate whole-body fuel allocation and energy homeostasis. The presence of functional thermogenic adipocytes is strongly associated with improved cardiometabolic health, protecting against obesity, type 2 diabetes, and cardiovascular disease. Understanding how these specialized cells sense and respond to systemic signals offers a powerful entry point for developing strategies to counteract metabolic disease.
https://www.academia.edu/journals/academia-biology/articles?source=journal-top-nav
sábado, 28 de marzo de 2026
Guselkumab shows minor added benefit for specific Crohn's disease patients
https://www.news-medical.net/news/20260327/Guselkumab-shows-minor-added-benefit-for-specific-Crohns-disease-patients.aspx
The human monoclonal antibody guselkumab has been approved for certain adults with moderately to severely active ulcerative colitis since April 2025. In a benefit assessment, the German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined whether guselkumab offers an added benefit to these patients.
TENS therapy reduces movement pain and fatigue in fibromyalgia patients
https://www.news-medical.net/news/20260327/TENS-therapy-reduces-movement-pain-and-fatigue-in-fibromyalgia-patients.aspx
Adding TENS (transcutaneous electrical nerve stimulation) to outpatient physical therapy reduced movement-based pain and fatigue in patients with fibromyalgia, and the effects lasted for at least six months, according to a new study led by researchers at University of Iowa Health Care.
Study links diagnostic timing to ovarian cancer survival outcomes
https://www.news-medical.net/news/20260327/UStudy-links-diagnostic-timing-to-ovarian-cancer-survival-outcomes.aspx
The study "Diagnostic Timing and Ovarian Cancer Survival in North Carolina" has been published in the latest issue of JAMA Network Open. Led by a team of UNC-Chapel Hill researchers, this study explored the relationship between survival and how quickly patients are diagnosed with ovarian cancer.
New analysis reveals flaws in traditional BMI classification system
https://www.news-medical.net/news/20260327/New-analysis-reveals-flaws-in-traditional-BMI-classification-system.aspx
Research from Italy to be presented at this year's European Congress on Obesity (ECO 2026, Istanbul, Turkey, 12-15 May) and published in the journal Nutrients shows that when the gold standard technique of dual-energy X-ray absorptiometry (DXA) is used to measure body fat in the general population, it shows that the traditional WHO body mass index (BMI) classification system misidentifies significant numbers of people as having overweight or obesity.
Global meningitis deaths remain high despite progress since 1990
https://www.news-medical.net/news/20260327/Global-meningitis-deaths-remain-high-despite-progress-since-1990.aspx
In 2023, globally 259,000 people died from meningitis and 2.5 million people were infected with the disease, suggests a study published in The Lancet Neurology. Although death and infection rates have declined significantly since 1990, progress is insufficient to meet the WHO targets of a 50% reduction in infections and 70% reduction in deaths by 2030.
Dandelion leaves boost brain-protective compounds after digestion
https://www.news-medical.net/news/20260327/Dandelion-leaves-boost-brain-protective-compounds-after-digestion.aspx
A common wild plant may hold hidden brain benefits. Dandelion leaf polyphenols survive digestion and continue targeting pathways associated with Alzheimer’s disease.
Privacy Check: Who’s Tracking You Now? By Ivanhoe Broadcast News on March 24, 2026
https://www.ivanhoe.com/smart-living/privacy-check-whos-tracking-you-now/
Orlando, Fla. (Ivanhoe Newswire) — Smart devices are everywhere, in our pockets, in our living rooms, even in our cars! But as more of our lives go digital, experts warn the data these devices collect may be far more extensive and far more personal than many people realize. Privacy surveys show more than half of consumers don’t trust smart devices to protect their personal data, and nearly three-quarters worry their information is used without their permission.
Scratch Season: Hidden Health Risks For Pets This Spring By Ivanhoe Broadcast News on March 25, 2026
https://www.ivanhoe.com/smart-living/scratch-season-hidden-health-risks-for-pets-this-spring/
Orlando, Fla. (Ivanhoe Newswire) — Spring fever isn’t just hitting people, it’s hitting pets. New national forecasts show flea and tick season is starting earlier and lasting longer across much of the U.S. Veterinarians are also seeing a spike in dog allergies with symptoms many pet parents don’t realize are allergy related.
Gramping: Spring Break For Teens & Grandparents By Ivanhoe Broadcast News on March 26, 2026
https://www.ivanhoe.com/smart-living/gramping-spring-break-for-teens-grandparents/
Orlando, Fla. (Ivanhoe Newswire) — When you think of family Spring break vacations with your teen, you might think of beach trips or theme park getaways. Now, many families are opting for “gramping,” it’s when grandparents and grandchildren vacation together and leave the parents at home.
The Right Workout For Your Personality By Ivanhoe Broadcast News on March 27, 2026
https://www.ivanhoe.com/smart-living/the-right-workout-for-your-personality/
Orlando, Fla. (Ivanhoe Newswire) — March is a time when many people start to rethink their health, especially as we focus on heart and overall wellness. Experts say staying active is one of the most powerful ways to protect your health. But it turns out how you exercise may depend on who you are.
Screen Smarts: Family Media Diets By Ivanhoe Broadcast News on April 26, 2025
https://www.ivanhoe.com/positive-parenting/screen-smarts-family-media-diets/
SOUTH KINGSTON, R.I. (Ivanhoe Newswire) — In today’s digital world, it’s easy for kids to consume endless hours of screen time. But what are they watching? And how can parents make sure their teens and preteens are not consuming too much of the wrong type of media — especially when it comes to important but complex issues happening around the world like war, politics, violence, and natural disasters? One approach experts suggest is putting families on “media diets.”
Toxic Trio: Allergies, Heat & Lyme Disease By Ivanhoe Broadcast News on April 19, 2025
https://www.ivanhoe.com/positive-parenting/toxic-trio-allergies-heat-lyme-disease/
CHARLOTTESVILLE, Va. (Ivanhoe Newswire) — Our changing climate is creating new health risks for children — longer allergy seasons, extreme heat affecting young athletes, and Lyme disease spreading to new areas. As these threats grow, parents and pediatricians need to be proactive in protecting children’s health and well-being. Allergies
You Have Cancer! Living Decades After Diagnosis By Ivanhoe Broadcast News on April 3, 2026
https://www.ivanhoe.com/?p=36885&preview=1&_ppp=f44454a89c
RALEIGH, NC. (Ivanhoe Newswire) — A cancer diagnosis doesn’t always mean what it used to. New data from the American Cancer Society shows the U.S. cancer death rate has fallen significantly since 1991, preventing nearly five million deaths. More than 18 million Americans are now living after a cancer diagnosis, and that number is expected to surpass 22 million by 2030.
The Key to a Woman’s Body: Estrogen By Ivanhoe Broadcast News on April 2, 2026
https://www.ivanhoe.com/?p=36882&preview=1&_ppp=b14c466eae
ORLANDO, Fla. (Ivanhoe Newswire) — Estrogen is the main female hormone that is produced from birth through menopause. It is made up of estrone, estradiol, and estriol, which fluctuate throughout a woman’s life, starting low at birth, rising quickly during puberty, then dropping off after menopause. The levels also change during menstruation and pregnancy. This means there’s a delicate, ever-changing balance between what’s normal and abnormal.
New Lungs Save Sadie! By Ivanhoe Broadcast News on April 1, 2026
https://www.ivanhoe.com/?p=36879&preview=1&_ppp=82bea9b7ab
STANFORD, Calif. (Ivanhoe Newswire) — Every so often, doctors run into a condition so rare that it has them puzzled. With its non-specific symptoms, PVOD is one of them. Seven-year-old Sadie Jackson counts herself lucky to be doing well after receiving a delayed diagnosis for this deadly disease.
viernes, 27 de marzo de 2026
Politicisation of the US FDA: eroding integrity and trust The Lancet ++ +... +
Switch to single-tablet bictegravir–lenacapavir from a complex HIV regimen (ARTISTRY-1): a randomised, open-label, phase 3 clinical trial
Prof Chloe Orkin, MDa c.m.orkin@qmul.ac.uk ∙ Peter J Ruane, MDb ∙ Malcolm Hedgcock, MDc ∙ Cyril Gaultier, MDd ∙ Prof Marcelo H Losso, MDe,f ∙ Benoit Trottier, MDg ∙ et al.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00307-7/fulltext?dgcid=raven_jbs_etoc_feature_lancet
Politicisation of the US FDA: eroding integrity and trust
The Lancet
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00600-8/fulltext?dgcid=raven_jbs_etoc_email
Mar 28, 2026
Volume 407Number 10535p1209-1302, e7-e19
https://www.thelancet.com/journals/lancet/issue/vol407no10535/PIIS0140-6736(26)X2010-4
Sepsis
Prof Mervyn Singer, FRCPa m.singer@ucl.ac.uk ∙ Prof Derek C Angus, FRCPb ∙ Prof Djillali Annane, MDc,d ∙ Prof Michael Bauer, MDe ∙ Prof Andre C Kalil, MDf ∙ Prof Michael Klompas, MDg,h ∙ et al
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)02422-5/abstract?dgcid=raven_jbs_etoc_feature_lancet
Sepsis is defined as a dysregulated host response to infection that leads to life-threatening organ dysfunction. The infectious insult triggers a dysregulated immune response that variably activates and suppresses multiple body system functions. Susceptibility to either developing or succumbing to sepsis is influenced by pathogen load and virulence; site of infection; host factors, including genetics, biological variability, comorbidities, immunosuppression, and extremes of age; and a wide range of external influences, such as social deprivation and local environment. Increasing appreciation of the underlying pathobiology has identified differing biological signatures with variable temporal evolution. This variability highlights the requirement to individualise treatment with targeted interventions guided by rapidly accessible biomarkers. Although improved outcomes have been obtained with better prevention, early recognition, and treatment, sepsis is a major cause of global mortality and morbidity. All populations having the benefits currently enjoyed by a privileged few is imperative. This Seminar aims to unravel the complexity of the condition, describing epidemiology and pathophysiology, evolving fundamental shifts, patient management, current challenges, and future developments.
Adding Chemo to Osimertinib Doubles Progression-Free Survival in Advanced NSCLC Kerri Wachter March 27, 2026
Elinzanetant Reduces Vasomotor Symptoms in Breast Cancer Sara Freeman Medscape Europe March 27, 2026
Carboplatin De-Escalation Gains Ground in Early HER2+ Breast Cancer Megan Brooks March 27, 2026
Dignity and mental health in Latin America: Peruvian observations and perspectives Renato D. Alarcón* [1,2] , Luis Matos-Retamozo [2,3]
https://www.academia.edu/2997-9196/3/1/10.20935/MHealthWellB8170
Abstract
This is a concise literature-based delineation of dignity and its connections with important mental health issues in the Latin American continent. This review examines the relationship between dignity and mental health in Latin America, focusing mostly on Peruvian socio-cultural studies and clinical perspectives. Drawing on published literature, an introductory geographic description and a historical narrative supported by socio-demographic data and cultural realities of the region, the review explores how dignity is shaped by cultural identity and by the mestizaje process as a decisive ontological feature. A series of seven cases covering different aspects of the impact of clinical events on the dignity of the protagonists is presented. Dignity is explored from the perspective of native healers, mothers and human rights principles, as well as its fragility in the face of socio-political, racism-induced conflicts, and sectarian/religious deformations. The difficulties faced in overcoming reductionistic and alienating influences, as well as social inequalities affecting dignity, are discussed. The review emphasizes, in turn, its consideration as one of the central issues of psychotherapeutic approaches and much-needed investigation projects.
https://www.academia.edu/journals/academia-mental-health-and-well-being/articles?source=journal-top-nav
Osteoporosis: A Bare-Bones Guide to Diagnosis and Management Namrata Singh, MD; Steven N, Berney, MD March 17, 2026 ++++
Osteoporosis: A Bare-Bones Guide to Diagnosis and Management
Namrata Singh, MD; Steven N, Berney, MD
https://reference.medscape.com/p11/osteoporosis-bare-bones-guide-diagnosis-and-management-2026a10006zl?ecd=wnl_critimg_260327_mscpref_etid8216619&uac=148436CN&impID=8216619
March 17, 2026
Osteoporosis is a progressive systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. It is a chronic condition of multifactorial etiology that is usually clinically silent for many years.
AI Tool Could Help Identify Patients at Risk for Osteoporosis and Osteopenia
Meaghan Lee Callaghan
https://www.medscape.com/viewarticle/ai-tool-could-help-identify-patients-risk-osteoporosis-and-2026a10006ti?ecd=wnl_critimg_260327_mscpref_etid8216619&uac=148436CN&impID=8216619
March 05, 2026
Early Hormone Replacement Therapy Linked to Lower Osteoporosis Risk in Postmenopausal Women
Lara Salahi
https://www.medscape.com/viewarticle/early-hormone-replacement-therapy-linked-lower-osteoporosis-2026a10006oo?ecd=wnl_critimg_260327_mscpref_etid8216619&uac=148436CN&impID=8216619
March 04, 2026
Consensus: Bisphosphonates for Aromatase Inhibitor Bone Loss
Nancy A. Melville
https://www.medscape.com/viewarticle/consensus-bisphosphonates-aromatase-inhibitor-bone-loss-2025a1000rta?ecd=wnl_critimg_260327_mscpref_etid8216619&uac=148436CN&impID=8216619
October 15, 2025
jueves, 26 de marzo de 2026
CONSORT-Children and Adolescents (CONSORT-C) 2026 extension statement: enhancing the reporting and impact of paediatric randomised trials ++... ++
CONSORT-Children and Adolescents (CONSORT-C) 2026 extension statement: enhancing the reporting and impact of paediatric randomised trials
Ami Baba, MResa ∙ Maureen Smith, MEdb ∙ Prof Beth K Potter, PhDc ∙ Prof An-Wen Chan, MD DPhild ∙ Prof David Moher, PhDc,e ∙ Alene Toulany, MD MSca,f,g,h,i ∙ et al.
https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(26)00004-0/fulltext?dgcid=hubspot_update_feature_updatealerts_lanchi&utm_campaign=update-lanchi&utm_medium=email&_hsenc=p2ANqtz-9PpOxWoRN9nBxg82XCd0EXyBfOcsfE4VQ2l4VWRq_TGK64FHhP8iqASeU-PrDi3nlTDVrkutjd3X99l30ePDpL4-qJfA&_hsmi=410564769&utm_content=410486566&utm_source=hs_email
Editorial
p233
CONSORT-C: a shared responsibility for truth and quality
The Lancet Child & Adolescent Health
https://www.thelancet.com/journals/lanchi/issue/vol10no4/PIIS2352-4642(26)X2002-8
The association between academic pressure and adolescent depressive symptoms and self-harm: a longitudinal, prospective study in England
Xuchen Guo, MSca,* ∙ Marie A E Mueller, PhDa,* ∙ Jessica M Armitage, PhDb,c ∙ Prof Chris Bonell, PhDd ∙ Prof Tamsin J Ford, MD PhDe ∙ Prof Ann John, MD PhDf ∙ et al.
https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(25)00342-6/fulltext?dgcid=hubspot_update_feature_updatealerts_lanchi&utm_campaign=update-lanchi&utm_medium=email&_hsenc=p2ANqtz-82nXn0_UbzaSpnhY_FxFqCEjSeSYcjG4-j7YZfsdpnMXAqZG5ITHgxPtEnVVwZmlax4Q8K2kDNMyx-v3FE_qjiq3fL7Q&_hsmi=410564769&utm_content=410486566&utm_source=hs_email
Age distribution of respiratory syncytial virus disease in children younger than 5 years in low-income and middle-income countries: a systematic review and meta-analysis
Sarwat Mahmud, MPHa,* ∙ Kevin van Zandvoort, PhDa,* ∙ Ling Guo, MMedb ∙ Prof You Li, PhDb,c ∙ Prof Harish Nair, PhDc ∙ Daniel R Feikin, MDd ∙ Erin Sparrow, PhDd ∙ Fahmida Chowdhury, MDe ∙ Prof Cheryl Cohen, PhDf,g ∙ Prof Ghassan S Dbaibo, MDh ∙ Angela Gentile, MDi ∙ Christopher J Gill, MDj ∙ Prof Aubree Gordon, PhDk ∙ Katherine C Horton, PhDa ∙ Prof Qing Cao, MDl ∙ Kirill Stolyarov, MScm ∙ Prof Andrew D Clark, PhD
https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(25)00349-9/fulltext?dgcid=hubspot_update_feature_updatealerts_lanchi&utm_campaign=update-lanchi&utm_medium=email&_hsenc=p2ANqtz-_7ULmD4jdhIHDjF58EtpFqjmAjC4Y4cIz5zdOwkV5fy5O7QJY8LatEg71PEfSlAnPndLLc1gq5xpsAZg69ja0p14e_ew&_hsmi=410564769&utm_content=410486566&utm_source=hs_email
GoGoVax dispels hopes for gonorrhoea vaccination The Lancet Infectious Diseases +++ +...
GoGoVax dispels hopes for gonorrhoea vaccination
The Lancet Infectious Diseases
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00126-X/fulltext?dgcid=raven_jbs_etoc_email
Comparison of the performance and costs of testing algorithms using rapid diagnostic tests for detection and treatment of syphilis among pregnant individuals and men who have sex with men: a modelling study
Ying Zhang, MPHa,b Ying.zhang2@monash.edu ∙ Prof Eric P F Chow, PhDa,b,c ∙ Prof Lei Zhang, PhDa,b ∙ Prof Christopher K Fairley, PhDa,b ∙ Prof Jason J Ong, PhD
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00588-2/abstract?dgcid=raven_jbs_etoc_feature_laninf
Global burden of lower respiratory infections and aetiologies, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
GBD 2023 Lower Respiratory Infections and Antimicrobial Resistance Collaborators
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00689-9/abstract?dgcid=raven_jbs_etoc_feature_laninf
Apr 2026
Volume 26Number 4p329-438, e209-e269
https://www.thelancet.com/journals/laninf/issue/vol26no4/PIIS1473-3099(26)X2003-5
Can AI chatbots help brain tumor patients understand their care?
https://www.news-medical.net/news/20260326/Can-AI-chatbots-help-brain-tumor-patients-understand-their-care.aspx
AI tools could transform how brain tumor patients access and understand critical care information, but without careful oversight, the same technology may introduce new risks and uncertainties.
Can Genetics Guide Treatment Selection in Irritable Bowel Syndrome?
https://www.news-medical.net/life-sciences/Can-Genetics-Guide-Treatment-Selection-in-Irritable-Bowel-Syndrome.aspx
Although genetic and microbiome research is beginning to uncover biological drivers of treatment variability in IBS, current evidence highlights that most applications remain exploratory, with limited integration into everyday clinical practice.