Blinatumomab Outperforms Chemotherapy in High-Risk B-ALL Randy Dotinga June 17, 2026 ++++++

Blinatumomab Outperforms Chemotherapy in High-Risk B-ALL Randy Dotinga https://www.medscape.com/viewarticle/blinatumomab-outperforms-chemotherapy-high-risk-b-all-2026a1000kfo June 17, 2026 Replacing two blocks of chemotherapy with two blocks of the bispecific antibody blinatumomab significantly improved event-free survival in children with high-risk B-cell acute lymphoblastic leukemia (B-ALL), according to findings from the randomized, phase 3 AIEOP-BFM ALL 2017 trial. GLP-1s Tied to Lower Cancer Risk in Patients With Obesity Will Pass https://www.medscape.com/viewarticle/glp-1s-tied-lower-cancer-risk-patients-obesity-2026a1000kg6 June 17, 2026 Individuals with obesity without diabetes taking GLP-1 receptor agonists (RAs) may have a reduced risk for certain cancers, a new study suggests. Is There a Role for Stimulants in Beating Cancer Fatigue? Ernie Mundell https://www.medscape.com/viewarticle/there-role-stimulants-beating-cancer-fatigue-2026a1000ked June 17, 2026 Current guidelines on treating cancer fatigue suggest that stimulants like methylphenidate be used sparingly if at all. But a recent meta-analysis supports a bigger role for the medications, possibly as a bridge to nondrug therapies. Water Ablation Therapy Shows Early Promise for Prostate Cancer Edited by Madhurima Roy https://www.medscape.com/viewarticle/water-ablation-therapy-shows-early-promise-prostate-cancer-2026a1000kdi June 17, 2026 Transurethral ablation of Gleason grade group 2 (GG2) lesions using water vapor therapy cleared the area of prostate cancer in 75% of men and 91% had no GG2 or higher-grade cancer remaining at 6 months. Combination Treatment May Improve Multiple Myeloma Outcomes Cristina Ferrario https://www.medscape.com/viewarticle/combination-treatment-may-improve-multiple-myeloma-outcomes-2026a1000kda Medscape Europe logo June 17, 2026 STOCKHOLM — Patients with relapsed or refractory multiple myeloma (RRMM) benefit from teclistamab plus daratumumab (Tec-Dara), irrespective of cytogenetic and functional risk status, according to research presented at the European Hematology Association (EHA) 2026 Congress. Pre-Resection MRI May Incorrectly Stage Large Rectal Polyps Edited by Mandeep Singh Rawat https://www.medscape.com/viewarticle/pre-resection-mri-may-incorrectly-stage-large-rectal-polyps-2026a1000ke3 June 17, 2026 In 44 patients with large rectal polyps referred for endoscopic resection, pelvic MRI overstaged tumor depth (T-stage) and nodal status (N-stage) in 38.6% and 2.3% of cases, respectively, potentially leading to unnecessary surgery. Endoscopic resection provided definitive histologic staging and was an effective organ-sparing treatment approach, with no recurrences observed during follow-up.