THE OBESITY REVOLUTION A new generation of obesity drugs is transforming patients’ lives, dividing medical experts, and spurring the biggest business battle in years. Known as GLP-1-based drugs, this medication class could have the medical and societal impact of blockbuste…

https://www.statnews.com/category/the-obesity-revolution/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9UQ02Vdmn6qc85sOD1OAP7ngwMw3YxDr-pqnDv5P32wSoyWovTdZotFxdAzNc0-cpk1LWexoEbYy6iDWnBs8ycJWJfFg&_hsmi=307106714&utm_content=307106714&utm_source=hs_email Since GLP-1 drugs began revolutionizing the way we consider addressing obesity last year, academics have wondered if the injectable treatments could affect people’s cravings for substances. But drug companies have yet to get involved — until now. Novo Nordisk, which makes Ozempic and Wegovy, will test whether GLP-1 drugs can help people with alcohol-associated liver disease. The company will not test the drugs purely in relation to substance misuse. The primary outcome tested in the nine-month study will be changes in liver scarring, and one of the secondary outcomes is changes in alcohol consumption. The trial comes at a time when alcohol-associated liver disease has been surging among younger people and women, making it the leading cause for transplant in the U.S. Read more from my colleagues Isa Cueto and Elaine Chen. The new weight loss drugs are revolutionizing our understanding of desire. Food cravings could be just the beginning Megan Molteni By Megan Molteni https://www.statnews.com/2023/07/10/new-weight-loss-drugs-wegovy-food-cravings/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8j03E9NQeNhYihTgykm91sB-gNAb1e4iUKlhNBCT-D1I-vjiSCl-88o1hR3PgvF3Jn_2TJMp61w2B4ys4RHU2CT_roRg&_hsmi=307106714&utm_content=307106714&utm_source=hs_email Novo to test Wegovy and other obesity drugs against alcohol-related liver disease Isabella Cueto Elaine Chen By Isabella Cueto and Elaine Chen May 14, 2024 https://www.statnews.com/2024/05/14/wegovy-alcohol-related-liver-disease-novo-nordisk/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9gpD_qgUAhkXtpSE_NY4PB0PLfWqFK2O7Nh6uHZMRcbdmdXrv59oBOb4MsIPzDU9jfK8hawhxd1SMLDHZ1CBVf9m-Z6A&_hsmi=307106714&utm_content=307106714&utm_source=hs_email